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The map label for this gene is ubiA

Identifier: 182680616

GI number: 182680616

Start: 60725

End: 61624

Strand: Reverse

Name: ubiA

Synonym: XfasM23_0044

Alternate gene names: 182680616

Gene position: 61624-60725 (Counterclockwise)

Preceding gene: 182680618

Following gene: 182680612

Centisome position: 2.43

GC content: 53.78

Gene sequence:

>900_bases
ATGGCTTACGAACGCTTCACATCGGCGATCACACTACTACTGCATTGGCGCAACCGCCTTGATCCGTATTGGAAGCTGGC
ACGCGGCGACCGCCCTGTTGGCTTTTTGCTTCTGCTATGGCCCACCTGGTGGGCACTATGGTTAGCCGCCGACGGTGTAC
CACCATGGTGGACCCTCTGTGTCTTCACTACTGGCATCTGGCTGACACGCTCAGCCGGATGCGTCATCAACGACTACACC
GACAGATGGCTTGATCCACACGTCGAACGCACCTGCACACGCCCCTTGGTCACCGGGACCGTTTCACCACGCAACGCCCT
ACTGATGTTCGGCACATTGATGCTAATCGCCTTCGGCCTCGTGCTCACGATGAATCGGCTTACCGTATTACTTAGCGTGG
CGGGGCTATTTCTGGCTATGACCTATCCATATTTAAAGCGCTATACCCACCTACCCCAAGTTTACTTAGGCATAGCCTTT
GGCTGGGGTATTCCGATGGCCTTCGCTGCCATACAGGGGAAAGTACCAACGCTGGCTTGGTTACTATACGTTGCAAACAT
CCTATGGACCACGGCCTATGACACTTGGTATGCGATGGTTGATCGCGACGACGACATCAAAATGGGGGCTAAATCCACCG
CGATTTTGTTCGCTGACCTGGATCTAGTAGTACAAGGAGTGCTATACACACTCATGCTATTAACATTGTGTTTGGTCGGC
CTACGCGCCACGCTCTCCCACACCTACTGGATTAGTTTAATCTCAGCCGTAGCGCTCATCGGATACCAATTCATCATCGC
TCGACGTCGCGAACCCACCGCCTGTTTTCGCGCATTCATGCATAACAACTGGGTCGGCATGACGATCTTCGCTGGCATTG
CCCTTGCCACAACACACTGA

Upstream 100 bases:

>100_bases
TGATACTAAACCAAGAGCATGAACACATCCAGGTTTACAATCACCATATAAACAGCCCCCAATTTCCCCATAATCCTTCA
TCCGATAACTCACCGTGAGT

Downstream 100 bases:

>100_bases
CCCTCACTGACACGAATTGAATAAACAACGTGAACAAGCAACTCTATCAACATCATTCCAATCACCCGCCCAACCTAAAA
CCAATGGGGAAGACTACTTG

Product: 4-hydroxybenzoate octaprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MAYERFTSAITLLLHWRNRLDPYWKLARGDRPVGFLLLLWPTWWALWLAADGVPPWWTLCVFTTGIWLTRSAGCVINDYT
DRWLDPHVERTCTRPLVTGTVSPRNALLMFGTLMLIAFGLVLTMNRLTVLLSVAGLFLAMTYPYLKRYTHLPQVYLGIAF
GWGIPMAFAAIQGKVPTLAWLLYVANILWTTAYDTWYAMVDRDDDIKMGAKSTAILFADLDLVVQGVLYTLMLLTLCLVG
LRATLSHTYWISLISAVALIGYQFIIARRREPTACFRAFMHNNWVGMTIFAGIALATTH

Sequences:

>Translated_299_residues
MAYERFTSAITLLLHWRNRLDPYWKLARGDRPVGFLLLLWPTWWALWLAADGVPPWWTLCVFTTGIWLTRSAGCVINDYT
DRWLDPHVERTCTRPLVTGTVSPRNALLMFGTLMLIAFGLVLTMNRLTVLLSVAGLFLAMTYPYLKRYTHLPQVYLGIAF
GWGIPMAFAAIQGKVPTLAWLLYVANILWTTAYDTWYAMVDRDDDIKMGAKSTAILFADLDLVVQGVLYTLMLLTLCLVG
LRATLSHTYWISLISAVALIGYQFIIARRREPTACFRAFMHNNWVGMTIFAGIALATTH
>Mature_298_residues
AYERFTSAITLLLHWRNRLDPYWKLARGDRPVGFLLLLWPTWWALWLAADGVPPWWTLCVFTTGIWLTRSAGCVINDYTD
RWLDPHVERTCTRPLVTGTVSPRNALLMFGTLMLIAFGLVLTMNRLTVLLSVAGLFLAMTYPYLKRYTHLPQVYLGIAFG
WGIPMAFAAIQGKVPTLAWLLYVANILWTTAYDTWYAMVDRDDDIKMGAKSTAILFADLDLVVQGVLYTLMLLTLCLVGL
RATLSHTYWISLISAVALIGYQFIIARRREPTACFRAFMHNNWVGMTIFAGIALATTH

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family

Homologues:

Organism=Homo sapiens, GI260656052, Length=281, Percent_Identity=35.2313167259786, Blast_Score=174, Evalue=1e-43,
Organism=Escherichia coli, GI1790473, Length=283, Percent_Identity=53.7102473498233, Blast_Score=293, Evalue=7e-81,
Organism=Caenorhabditis elegans, GI17553718, Length=296, Percent_Identity=35.472972972973, Blast_Score=159, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI32565247, Length=297, Percent_Identity=35.016835016835, Blast_Score=148, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17553720, Length=355, Percent_Identity=29.8591549295775, Blast_Score=118, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI32565245, Length=152, Percent_Identity=36.8421052631579, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI32565243, Length=151, Percent_Identity=36.4238410596026, Blast_Score=91, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6324370, Length=279, Percent_Identity=31.8996415770609, Blast_Score=128, Evalue=1e-30,
Organism=Drosophila melanogaster, GI21355567, Length=279, Percent_Identity=36.5591397849462, Blast_Score=170, Evalue=8e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIA_XYLF2 (B2I675)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001828776.1
- GeneID:   6202069
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_0044
- HOGENOM:   HBG324383
- OMA:   YHYTLIR
- ProtClustDB:   PRK12848
- HAMAP:   MF_01635
- InterPro:   IPR006370
- InterPro:   IPR000537
- TIGRFAMs:   TIGR01474

Pfam domain/function: PF01040 UbiA

EC number: 2.5.1.-

Molecular weight: Translated: 33966; Mature: 33834

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1193adf8)-; HASH(0x13045f38)-; HASH(0x129d63f8)-; HASH(0x123bea20)-; HASH(0x12998acc)-; HASH(0x11be246c)-; HASH(0x12b53f88)-; HASH(0x12998910)-;

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYERFTSAITLLLHWRNRLDPYWKLARGDRPVGFLLLLWPTWWALWLAADGVPPWWTLC
CCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHH
VFTTGIWLTRSAGCVINDYTDRWLDPHVERTCTRPLVTGTVSPRNALLMFGTLMLIAFGL
HHHHHHHHCCCCCCEEECCHHHHCCCHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHH
VLTMNRLTVLLSVAGLFLAMTYPYLKRYTHLPQVYLGIAFGWGIPMAFAAIQGKVPTLAW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
LLYVANILWTTAYDTWYAMVDRDDDIKMGAKSTAILFADLDLVVQGVLYTLMLLTLCLVG
HHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
LRATLSHTYWISLISAVALIGYQFIIARRREPTACFRAFMHNNWVGMTIFAGIALATTH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCH
>Mature Secondary Structure 
AYERFTSAITLLLHWRNRLDPYWKLARGDRPVGFLLLLWPTWWALWLAADGVPPWWTLC
CHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHH
VFTTGIWLTRSAGCVINDYTDRWLDPHVERTCTRPLVTGTVSPRNALLMFGTLMLIAFGL
HHHHHHHHCCCCCCEEECCHHHHCCCHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHH
VLTMNRLTVLLSVAGLFLAMTYPYLKRYTHLPQVYLGIAFGWGIPMAFAAIQGKVPTLAW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
LLYVANILWTTAYDTWYAMVDRDDDIKMGAKSTAILFADLDLVVQGVLYTLMLLTLCLVG
HHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
LRATLSHTYWISLISAVALIGYQFIIARRREPTACFRAFMHNNWVGMTIFAGIALATTH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA