Click here to switch to the map view.

The map label for this gene is exoX [C]

Identifier: 170746460

GI number: 170746460

Start: 10586

End: 11455

Strand: Reverse

Name: exoX [C]

Synonym: Mrad2831_0010

Alternate gene names: 170746460

Gene position: 11455-10586 (Counterclockwise)

Preceding gene: 170746461

Following gene: 170746457

Centisome position: 0.19

GC content: 75.06

Gene sequence:

>870_bases
ATGACGGTCCTGGCCCTCGACTTCGAGACGGCCAACGAGCGGCGTGACAGCGCCTGCGCGGTGGGGCTCGCCTGGATCGC
GGATGGCCGGGTCGTGCGCCGCGAGAGCCACCTGATCCGGCCCCCCGAGATGCGCTTCGCACCGGGCAACATTCGCGTCC
ACGGCATCCTGCCGGCCGACGTCGCCGACAAGCCCGACTTCGCCGCCGTCATGGCGCCCTATCTCGGCGATCTCGCGCGC
GGGCTGATCCTGGCGCACAACGCGAGCTTCGATATCGGCGTCCTGCGCGCCGGCCTGACCCGGGCAGGCCTGCCGGTGCC
CGATCTCGCCTATCTCTGCACGGTCCAGGTGTCTCGCCGGGTCTTCCCGGCGCCGGAGGGCTGCGGGCTCGGCAAGGTCG
CGCGGCGCCTCGGCATCCGCTTCGAGCACCACGATGCCGGCGAGGACGCCTATGCGTGCGCGGAGATCGCGCTGGCCGCG
ATGCGCGAGCGGGCGGTCGCGGACATGCACGCCCTCGCGGCCGCGCTCGGCCTCCCGGTCACGCGGGCGGTCGGCGGTCC
CGCCGTGCCGCGCCGCGCGCCGGGAGCGATCAGCGGCCGGGCCCTGGCGGCCTTCCCCGAGGAGCCGGCGGCCCTGCGCT
TCGCCATGCGCGGGTCGACCGGCAACCGCTACCACGTCAGCCTCGAGGAGCGGCCGGGCGGCCCGGAGCTGCGCTGCACC
TGCACGGCGGGCCGCTACGGCATGCGCTGCCGCCACGTGAAGGCGCTGGAGGTCGGCGACATCACCGACCTGCTCTCGGA
CAATGCCGGCGACGTCGTGCTCCTCGCCCGGATGCTCGGCGCGAAGACCCGGGTCGCGGGCGCGGCCTGA

Upstream 100 bases:

>100_bases
TTGGCTGGCGATGGTGGCGCAGGGTTGAAGCCCGAGTCCGGCCGGCCTAGACCTCTCGGGGAACACCCCGAGAACTTCCA
CCCGGTATGGTTGAACCGCG

Downstream 100 bases:

>100_bases
CCGGTCAGGCCGCGTCGAGGCAGGCGCGGAAGGCCGCGACAGCGCGATCGACGTCGGCCGGCGCGATGTGCCGGTGCGTG
ACGAGCCGAAGCCGCCGCGC

Product: exonuclease RNase T and DNA polymerase III

Products: diphosphate; DNAn+1

Alternate protein names: Exonuclease RNAse T And DNA Polymerase III; DNA Polymerase III Epsilon Subunit; DNA Polymerase III Subunit Epsilon; 3-5' Exonuclease; DNA-Directed DNA Polymerase III Epsilon Chain; DNA-Directed DNA Polymerase III Epsilon Subunit; Exonuclease DNA Polymerase III Epsilon Subunit Family; DNA Polymerase III Alpha Subunit; Exonuclease Family Protein; DNA Polymerase III Alpha Chain; Transposase; DNAQ Family Exonuclease/DinG Family Helicase; Exonuclease With A BRCT Domain; DNA Polymerase Subunit III; Type III DNA Polymerase PolC; Exonuclease Superfamily; DNA Polymerase III Epsilon-Like Protein; DNA Polymerase Subunit III Alpha; DNA Polymerase III PolC-Type; Exonuclease Family; DNA Polymerase III Epsilon Subunit-Like 3-5 Exonuclease; DNA-Directed DNA Polymerase III Subunit Epsilon

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MTVLALDFETANERRDSACAVGLAWIADGRVVRRESHLIRPPEMRFAPGNIRVHGILPADVADKPDFAAVMAPYLGDLAR
GLILAHNASFDIGVLRAGLTRAGLPVPDLAYLCTVQVSRRVFPAPEGCGLGKVARRLGIRFEHHDAGEDAYACAEIALAA
MRERAVADMHALAAALGLPVTRAVGGPAVPRRAPGAISGRALAAFPEEPAALRFAMRGSTGNRYHVSLEERPGGPELRCT
CTAGRYGMRCRHVKALEVGDITDLLSDNAGDVVLLARMLGAKTRVAGAA

Sequences:

>Translated_289_residues
MTVLALDFETANERRDSACAVGLAWIADGRVVRRESHLIRPPEMRFAPGNIRVHGILPADVADKPDFAAVMAPYLGDLAR
GLILAHNASFDIGVLRAGLTRAGLPVPDLAYLCTVQVSRRVFPAPEGCGLGKVARRLGIRFEHHDAGEDAYACAEIALAA
MRERAVADMHALAAALGLPVTRAVGGPAVPRRAPGAISGRALAAFPEEPAALRFAMRGSTGNRYHVSLEERPGGPELRCT
CTAGRYGMRCRHVKALEVGDITDLLSDNAGDVVLLARMLGAKTRVAGAA
>Mature_288_residues
TVLALDFETANERRDSACAVGLAWIADGRVVRRESHLIRPPEMRFAPGNIRVHGILPADVADKPDFAAVMAPYLGDLARG
LILAHNASFDIGVLRAGLTRAGLPVPDLAYLCTVQVSRRVFPAPEGCGLGKVARRLGIRFEHHDAGEDAYACAEIALAAM
RERAVADMHALAAALGLPVTRAVGGPAVPRRAPGAISGRALAAFPEEPAALRFAMRGSTGNRYHVSLEERPGGPELRCTC
TAGRYGMRCRHVKALEVGDITDLLSDNAGDVVLLARMLGAKTRVAGAA

Specific function: Capable Of Degrading Both Single-Strand And Double- Strand DNA With 3' To 5' Polarity. Has Higher Affinity For ssDNA Ends Than For dsDNA. May Facilitate Recombinational Repair By Pre- Synaptic And/Or Post-Synaptic DNA Degradation. [C]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.7.7

Molecular weight: Translated: 30596; Mature: 30465

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: PS00022 EGF_1 ; PS50966 ZF_SWIM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLALDFETANERRDSACAVGLAWIADGRVVRRESHLIRPPEMRFAPGNIRVHGILPAD
CEEEEEECCCCCCCCCCHHHEEEEEECCCEEEECCCCCCCCCCCEECCCCEEEEEEECCC
VADKPDFAAVMAPYLGDLARGLILAHNASFDIGVLRAGLTRAGLPVPDLAYLCTVQVSRR
CCCCCCHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHCHHHCCCCCCCHHHHHHHHHHHC
VFPAPEGCGLGKVARRLGIRFEHHDAGEDAYACAEIALAAMRERAVADMHALAAALGLPV
CCCCCCCCCHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
TRAVGGPAVPRRAPGAISGRALAAFPEEPAALRFAMRGSTGNRYHVSLEERPGGPELRCT
HHHCCCCCCCCCCCCCCCCCEEEECCCCCCEEEEEEECCCCCEEEEEEECCCCCCCEEEE
CTAGRYGMRCRHVKALEVGDITDLLSDNAGDVVLLARMLGAKTRVAGAA
ECCCCCCCEEEEEEEEECCCHHHHHCCCCCCHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TVLALDFETANERRDSACAVGLAWIADGRVVRRESHLIRPPEMRFAPGNIRVHGILPAD
EEEEEECCCCCCCCCCHHHEEEEEECCCEEEECCCCCCCCCCCEECCCCEEEEEEECCC
VADKPDFAAVMAPYLGDLARGLILAHNASFDIGVLRAGLTRAGLPVPDLAYLCTVQVSRR
CCCCCCHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHCHHHCCCCCCCHHHHHHHHHHHC
VFPAPEGCGLGKVARRLGIRFEHHDAGEDAYACAEIALAAMRERAVADMHALAAALGLPV
CCCCCCCCCHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
TRAVGGPAVPRRAPGAISGRALAAFPEEPAALRFAMRGSTGNRYHVSLEERPGGPELRCT
HHHCCCCCCCCCCCCCCCCCEEEECCCCCCEEEEEEECCCCCEEEEEEECCCCCCCEEEE
CTAGRYGMRCRHVKALEVGDITDLLSDNAGDVVLLARMLGAKTRVAGAA
ECCCCCCCEEEEEEEEECCCHHHHHCCCCCCHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: deoxynucleoside triphosphate; DNAn

Specific reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA