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The map label for this gene is hpcR [H]

Identifier: 170024687

GI number: 170024687

Start: 2695107

End: 2695574

Strand: Direct

Name: hpcR [H]

Synonym: YPK_2462

Alternate gene names: 170024687

Gene position: 2695107-2695574 (Clockwise)

Preceding gene: 170024676

Following gene: 170024689

Centisome position: 57.47

GC content: 45.3

Gene sequence:

>468_bases
ATGCATGAATCACTGACCATCGCATTATTGCAGGCTCGTGAAGCCGCTATGGCTTTTTTTCGGCCTATCTTGAAAGCCAA
TCATCTGACTGAGCAGCAATGGCGGATCATTCGAGTGCTCGCGGATAATCGCTCAATTGATTTTCATGGGCTGGCCCGCC
AAACCTGTATTTTACGTCCAAGCCTAACGGGGATTTTGACGCGAATGGAGCGTAACAATTTGATTTTTCGCCTCAAACCC
GTCAACGATCAGCGCAAACTTTATGTCTCCTTAACTCAGGAGGGACAAAATTTGTATGACAACGCTCGGCCACAGGTTGA
AGAAGGTTACAGGCTAATTGAGGCAGCATTTTCACCAGATAAAATGGCGCAACTCTCTTTACTGCTGGATGAATTCATTA
CCGTGGGTAATAAACATCGGCAAGCGAATGAGATGTCAGAAAATGAGATGTTAGAAGATGAAGAGTGA

Upstream 100 bases:

>100_bases
TAAGGAATCGCTGGTGTCTGGCCCATCTGTCCGTATACTAAAAACAGCAGAGCCTCCCTCTAGGAGAGGATAAATTACTA
ACGTCGAGTCGTTGTTACTT

Downstream 100 bases:

>100_bases
TGGGTTTACGGCGTCTTTGCGTTCTGTCTGTTACCTCCGTCGCGGGTACGTTGTCAATAACCTCAGGGGAGCCGAAGCGC
CCCTGAGGTTCCACTCTCTG

Product: MarR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MHESLTIALLQAREAAMAFFRPILKANHLTEQQWRIIRVLADNRSIDFHGLARQTCILRPSLTGILTRMERNNLIFRLKP
VNDQRKLYVSLTQEGQNLYDNARPQVEEGYRLIEAAFSPDKMAQLSLLLDEFITVGNKHRQANEMSENEMLEDEE

Sequences:

>Translated_155_residues
MHESLTIALLQAREAAMAFFRPILKANHLTEQQWRIIRVLADNRSIDFHGLARQTCILRPSLTGILTRMERNNLIFRLKP
VNDQRKLYVSLTQEGQNLYDNARPQVEEGYRLIEAAFSPDKMAQLSLLLDEFITVGNKHRQANEMSENEMLEDEE
>Mature_155_residues
MHESLTIALLQAREAAMAFFRPILKANHLTEQQWRIIRVLADNRSIDFHGLARQTCILRPSLTGILTRMERNNLIFRLKP
VNDQRKLYVSLTQEGQNLYDNARPQVEEGYRLIEAAFSPDKMAQLSLLLDEFITVGNKHRQANEMSENEMLEDEE

Specific function: Repressor for the homoprotocatechuate catabolic pathway hpc operon [H]

COG id: COG1846

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012712
- InterPro:   IPR000835
- InterPro:   IPR023187
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 18024; Mature: 18024

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHESLTIALLQAREAAMAFFRPILKANHLTEQQWRIIRVLADNRSIDFHGLARQTCILRP
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHEEEEEECCCCCCCCCHHHHHEEECC
SLTGILTRMERNNLIFRLKPVNDQRKLYVSLTQEGQNLYDNARPQVEEGYRLIEAAFSPD
HHHHHHHHHHCCCEEEEEECCCCCCEEEEEEECCCCHHHCCCCCCHHHHHHHHHHHCCCH
KMAQLSLLLDEFITVGNKHRQANEMSENEMLEDEE
HHHHHHHHHHHHHHCCCCHHHHHHCCHHCCCCCCC
>Mature Secondary Structure
MHESLTIALLQAREAAMAFFRPILKANHLTEQQWRIIRVLADNRSIDFHGLARQTCILRP
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHEEEEEECCCCCCCCCHHHHHEEECC
SLTGILTRMERNNLIFRLKPVNDQRKLYVSLTQEGQNLYDNARPQVEEGYRLIEAAFSPD
HHHHHHHHHHCCCEEEEEECCCCCCEEEEEEECCCCHHHCCCCCCHHHHHHHHHHHCCCH
KMAQLSLLLDEFITVGNKHRQANEMSENEMLEDEE
HHHHHHHHHHHHHHCCCCHHHHHHCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8384293; 8550403 [H]