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The map label for this gene is sdaA [H]

Identifier: 170024676

GI number: 170024676

Start: 2683683

End: 2685047

Strand: Direct

Name: sdaA [H]

Synonym: YPK_2451

Alternate gene names: 170024676

Gene position: 2683683-2685047 (Clockwise)

Preceding gene: 170024675

Following gene: 170024687

Centisome position: 57.23

GC content: 51.28

Gene sequence:

>1365_bases
GTGATTAGCGTTTTTGACATGTTTAAGATTGGTATCGGTCCGTCCAGCTCTCATACCGTTGGGCCAATGAAAGCGGGTAA
GCAATTTGTCGATTTGCTGATAACCGAAGGATTGATGCCGTCTATCACGCGTGTTGCCGTCGATGTTTACGGCTCACTGT
CGCTGACCGGGAAAGGCCATCACACCGATATCGCCATTATTATGGGTCTGGCAGGTAACCTGCCTGATACCGTTGATATC
GACAGCATCCCCGCGTTTATCCGCGATGTTGAATTACGCCAAAAACTGATGTTGGCAAATGGCCTGCATGAAGTCGATTT
CCCCCGTGAAGGCGGGATGGTCTTCCGCAGCGATAATCTGCCACTGCATGAGAATGGCATGCAAATTCATGCTTTTGCTG
GCGATGAAAAAGTCCTCAGCAAAACATACTACTCCATCGGCGGTGGTTTTATCGTTGATGAAGAGAATTTTGGCAAAGCC
AGCGTGAATGACGTTAGCGTCCCCTACCCGTTTAACTCTGCTGCCGAAATATTAGCCAACTGCGAGCAAACTGGCCTGTC
TATCTCCGGTATGGTGATGCAGAATGAACTGGCGATGCACAGTAAAGAAGAGATTGAGTCCTATTTCACCGCCATCTGGC
AGACCATGCGCGCCTGTATCGATCGCGGTTTGAATACCGAGGGTGTGCTGCCTGGGCCACTGCGTGTACCACGTCGTGCA
TCGGCATTACGCCGCCTGCTGGTCTCTTCCGATAAGCTGTCCAGTGACCCCATGATTGTCATTGACTGGGTCAATATGTT
CGCACTGGCCGTGAATGAAGAAAATGCGGCAGGTGGACGTGTCGTGACGGCACCCACTAACGGGGCTTGCGGTATCGTTC
CGGCGGTTCTGGCCTATTACGATCACTTTATCGAACCGGTGACACCTGAAATCTTTATTCGTTATTTCCTCGCATCTGGT
GCCATCGGGATTTTGTATAAGATGAATGCTTCTATTTCTGGTGCAGAGGTGGGTTGTCAGGGCGAAGTGGGCGTTGCCTG
TTCAATGGCGGCCGCTGGTCTTGCTGAATTGCTGGGTGCTAGCCCGATCCAAGTCTGTATCGCAGCCGAGATTGGCATGG
AACACAACTTAGGTCTGACCTGCGACCCGGTTGCGGGTCAGGTACAGGTACCGTGTATTGAACGCAATGCGATTGCATCG
GTAAAAGCGATCAACTCCGCACGGATGGCGATACGCCGTACCAGTGAACCGCGCGTCTCCCTCGATAAAGTTATCGAAAC
GATGTTTGAAACAGGTAAAGATATGAATGCCAAATACCGCGAAACATCGCGTGGTGGCCTGGCGATTAAAGTGCAGTGTA
CTTGA

Upstream 100 bases:

>100_bases
CCGCGTCTAGCCACAAAGTTTTATACTTAATACAAATGTTCTCAAGCCCTATCAATCAGGCGCTGAGTATAATAATAGGT
TTTTGTGAAGGAGCTTTAGC

Downstream 100 bases:

>100_bases
TTTTTTTCGCTGACAGCTATCTTGAAACAACCCAAAGGGGAGCCAATGTATGACCGGTTTATACACAAAGCGCCCTTCGG
ACGGCTGACAAACCCCGATG

Product: L-serine dehydratase 1

Products: NA

Alternate protein names: SDH 1; L-serine deaminase 1; L-SD1 [H]

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MISVFDMFKIGIGPSSSHTVGPMKAGKQFVDLLITEGLMPSITRVAVDVYGSLSLTGKGHHTDIAIIMGLAGNLPDTVDI
DSIPAFIRDVELRQKLMLANGLHEVDFPREGGMVFRSDNLPLHENGMQIHAFAGDEKVLSKTYYSIGGGFIVDEENFGKA
SVNDVSVPYPFNSAAEILANCEQTGLSISGMVMQNELAMHSKEEIESYFTAIWQTMRACIDRGLNTEGVLPGPLRVPRRA
SALRRLLVSSDKLSSDPMIVIDWVNMFALAVNEENAAGGRVVTAPTNGACGIVPAVLAYYDHFIEPVTPEIFIRYFLASG
AIGILYKMNASISGAEVGCQGEVGVACSMAAAGLAELLGASPIQVCIAAEIGMEHNLGLTCDPVAGQVQVPCIERNAIAS
VKAINSARMAIRRTSEPRVSLDKVIETMFETGKDMNAKYRETSRGGLAIKVQCT

Sequences:

>Translated_454_residues
MISVFDMFKIGIGPSSSHTVGPMKAGKQFVDLLITEGLMPSITRVAVDVYGSLSLTGKGHHTDIAIIMGLAGNLPDTVDI
DSIPAFIRDVELRQKLMLANGLHEVDFPREGGMVFRSDNLPLHENGMQIHAFAGDEKVLSKTYYSIGGGFIVDEENFGKA
SVNDVSVPYPFNSAAEILANCEQTGLSISGMVMQNELAMHSKEEIESYFTAIWQTMRACIDRGLNTEGVLPGPLRVPRRA
SALRRLLVSSDKLSSDPMIVIDWVNMFALAVNEENAAGGRVVTAPTNGACGIVPAVLAYYDHFIEPVTPEIFIRYFLASG
AIGILYKMNASISGAEVGCQGEVGVACSMAAAGLAELLGASPIQVCIAAEIGMEHNLGLTCDPVAGQVQVPCIERNAIAS
VKAINSARMAIRRTSEPRVSLDKVIETMFETGKDMNAKYRETSRGGLAIKVQCT
>Mature_454_residues
MISVFDMFKIGIGPSSSHTVGPMKAGKQFVDLLITEGLMPSITRVAVDVYGSLSLTGKGHHTDIAIIMGLAGNLPDTVDI
DSIPAFIRDVELRQKLMLANGLHEVDFPREGGMVFRSDNLPLHENGMQIHAFAGDEKVLSKTYYSIGGGFIVDEENFGKA
SVNDVSVPYPFNSAAEILANCEQTGLSISGMVMQNELAMHSKEEIESYFTAIWQTMRACIDRGLNTEGVLPGPLRVPRRA
SALRRLLVSSDKLSSDPMIVIDWVNMFALAVNEENAAGGRVVTAPTNGACGIVPAVLAYYDHFIEPVTPEIFIRYFLASG
AIGILYKMNASISGAEVGCQGEVGVACSMAAAGLAELLGASPIQVCIAAEIGMEHNLGLTCDPVAGQVQVPCIERNAIAS
VKAINSARMAIRRTSEPRVSLDKVIETMFETGKDMNAKYRETSRGGLAIKVQCT

Specific function: Deaminates also threonine, particularly when it is present in high concentration [H]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1788116, Length=453, Percent_Identity=84.326710816777, Blast_Score=807, Evalue=0.0,
Organism=Escherichia coli, GI1789161, Length=451, Percent_Identity=76.4966740576497, Blast_Score=729, Evalue=0.0,
Organism=Escherichia coli, GI48994925, Length=453, Percent_Identity=71.523178807947, Blast_Score=665, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 48678; Mature: 48678

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISVFDMFKIGIGPSSSHTVGPMKAGKQFVDLLITEGLMPSITRVAVDVYGSLSLTGKGH
CCCCEEEHEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEECCCCC
HTDIAIIMGLAGNLPDTVDIDSIPAFIRDVELRQKLMLANGLHEVDFPREGGMVFRSDNL
CCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCC
PLHENGMQIHAFAGDEKVLSKTYYSIGGGFIVDEENFGKASVNDVSVPYPFNSAAEILAN
CCCCCCCEEEEECCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHH
CEQTGLSISGMVMQNELAMHSKEEIESYFTAIWQTMRACIDRGLNTEGVLPGPLRVPRRA
HHHHCCEEEEEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHH
SALRRLLVSSDKLSSDPMIVIDWVNMFALAVNEENAAGGRVVTAPTNGACGIVPAVLAYY
HHHHHHHHCCCCCCCCCEEEEEECCEEEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHH
DHFIEPVTPEIFIRYFLASGAIGILYKMNASISGAEVGCQGEVGVACSMAAAGLAELLGA
HHHHCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
SPIQVCIAAEIGMEHNLGLTCDPVAGQVQVPCIERNAIASVKAINSARMAIRRTSEPRVS
CHHHEEEEEECCCCCCCCEEECCCCCCEECCEECCCHHHHHHHHHHHHHHHCCCCCCCHH
LDKVIETMFETGKDMNAKYRETSRGGLAIKVQCT
HHHHHHHHHHCCCCCCCCHHCCCCCCEEEEEEEC
>Mature Secondary Structure
MISVFDMFKIGIGPSSSHTVGPMKAGKQFVDLLITEGLMPSITRVAVDVYGSLSLTGKGH
CCCCEEEHEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEECCCCC
HTDIAIIMGLAGNLPDTVDIDSIPAFIRDVELRQKLMLANGLHEVDFPREGGMVFRSDNL
CCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCC
PLHENGMQIHAFAGDEKVLSKTYYSIGGGFIVDEENFGKASVNDVSVPYPFNSAAEILAN
CCCCCCCEEEEECCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHH
CEQTGLSISGMVMQNELAMHSKEEIESYFTAIWQTMRACIDRGLNTEGVLPGPLRVPRRA
HHHHCCEEEEEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHH
SALRRLLVSSDKLSSDPMIVIDWVNMFALAVNEENAAGGRVVTAPTNGACGIVPAVLAYY
HHHHHHHHCCCCCCCCCEEEEEECCEEEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHH
DHFIEPVTPEIFIRYFLASGAIGILYKMNASISGAEVGCQGEVGVACSMAAAGLAELLGA
HHHHCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
SPIQVCIAAEIGMEHNLGLTCDPVAGQVQVPCIERNAIASVKAINSARMAIRRTSEPRVS
CHHHEEEEEECCCCCCCCEEECCCCCCEECCEECCCHHHHHHHHHHHHHHHCCCCCCCHH
LDKVIETMFETGKDMNAKYRETSRGGLAIKVQCT
HHHHHHHHHHCCCCCCCCHHCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2504697; 8436113; 9097040; 9278503 [H]