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The map label for this gene is sapC [H]

Identifier: 170024129

GI number: 170024129

Start: 2096573

End: 2097463

Strand: Reverse

Name: sapC [H]

Synonym: YPK_1890

Alternate gene names: 170024129

Gene position: 2097463-2096573 (Counterclockwise)

Preceding gene: 170024130

Following gene: 170024128

Centisome position: 44.73

GC content: 51.63

Gene sequence:

>891_bases
ATGCCCTTCGATAATGTCTACCGCGAAAAGAAAATGCCCAGCCCATTGCTGTATACCTGGCGTCTTTTCTCTTCTGATGG
CCTGGCGATGGTGGGTTTCTACGGCGTCTTGGGTTTATTATTGCTGTGTCTGTTGGGGAGCACGCTTGCGCCTTATACTC
TCGATCAACAGTTTTTAGGCTATCAGCTATTGCCACCTTCTTGGTCACGTTATGGCAATGTTTCCTTCTTCCTAGGGACC
GATGACCTCGGTCGTGATGTATTGAGCCGCTTACTGACAGGTACCGCGTCTACTTATGGTTCAGCGCTCCTGGTCACCGT
AGCTGCGGCGTTGTGTGCCATTGTTCTCGGTGTATTTGCCGGTATCACCCGTGGTTTGCGGTCCGCGATCCTTAATCATG
TGCTGGATACACTGCTCTCAATACCTTCACTGCTGTTAGCCATCATCGTGGTCGCCTTTGTCGGGCCAAGTTTGGAACAT
GCGATGTTTGCCGTTTGGCTGGCGCTGTTACCACGAATGGTGCGAACCATTTATAGCGCAGTGCATGATGAGCTTGATAA
AGAATATGTGATTGCAGCCCGTCTGGACGGCGCATCAACACCGCACATTCTGGCCTATGCCATCTTGCCGAATATCGCCT
CAGTCCTGGTCACTGAGTTTACCCGAGCGTTATCAATGGCGATCCTGGATATTGCCGCATTAGGTTTCCTTGACCTCGGC
GCACAATTACCCTCTCCCGAATGGGGAGCAATGCTCGGTGATTCGCTGGATTTGGTTTATGTCGCACCATGGACCGTGAT
GCTGCCAGGCGGCGCAATTTTGGTTAGTGTACTGTTGGTTAATCTGCTGGGTGATGGTATGCGCCGTGCCATTAATGCGG
GGGTGGAATAA

Upstream 100 bases:

>100_bases
TCTGCGGGGGTGATGGTCGTGGGTTCGTTAGTGATCGTTATTAATGTGCTGTCGGATATTCTGGGTGCCATGATGACCCC
GTTAAAGCATAAGGAATGGT

Downstream 100 bases:

>100_bases
TGCCATTACTTGATATTCGCAACCTTACCATCGAATTTATGACGTCAGAAGGGCCAGTAAAAGCCGTTGACCGCATCAGC
ATGACCTTAACTGAGGGCGA

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MPFDNVYREKKMPSPLLYTWRLFSSDGLAMVGFYGVLGLLLLCLLGSTLAPYTLDQQFLGYQLLPPSWSRYGNVSFFLGT
DDLGRDVLSRLLTGTASTYGSALLVTVAAALCAIVLGVFAGITRGLRSAILNHVLDTLLSIPSLLLAIIVVAFVGPSLEH
AMFAVWLALLPRMVRTIYSAVHDELDKEYVIAARLDGASTPHILAYAILPNIASVLVTEFTRALSMAILDIAALGFLDLG
AQLPSPEWGAMLGDSLDLVYVAPWTVMLPGGAILVSVLLVNLLGDGMRRAINAGVE

Sequences:

>Translated_296_residues
MPFDNVYREKKMPSPLLYTWRLFSSDGLAMVGFYGVLGLLLLCLLGSTLAPYTLDQQFLGYQLLPPSWSRYGNVSFFLGT
DDLGRDVLSRLLTGTASTYGSALLVTVAAALCAIVLGVFAGITRGLRSAILNHVLDTLLSIPSLLLAIIVVAFVGPSLEH
AMFAVWLALLPRMVRTIYSAVHDELDKEYVIAARLDGASTPHILAYAILPNIASVLVTEFTRALSMAILDIAALGFLDLG
AQLPSPEWGAMLGDSLDLVYVAPWTVMLPGGAILVSVLLVNLLGDGMRRAINAGVE
>Mature_295_residues
PFDNVYREKKMPSPLLYTWRLFSSDGLAMVGFYGVLGLLLLCLLGSTLAPYTLDQQFLGYQLLPPSWSRYGNVSFFLGTD
DLGRDVLSRLLTGTASTYGSALLVTVAAALCAIVLGVFAGITRGLRSAILNHVLDTLLSIPSLLLAIIVVAFVGPSLEHA
MFAVWLALLPRMVRTIYSAVHDELDKEYVIAARLDGASTPHILAYAILPNIASVLVTEFTRALSMAILDIAALGFLDLGA
QLPSPEWGAMLGDSLDLVYVAPWTVMLPGGAILVSVLLVNLLGDGMRRAINAGVE

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4171

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787549, Length=296, Percent_Identity=77.027027027027, Blast_Score=457, Evalue=1e-130,
Organism=Escherichia coli, GI1789964, Length=283, Percent_Identity=40.9893992932862, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1787760, Length=250, Percent_Identity=36.4, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1787054, Length=289, Percent_Identity=31.1418685121107, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1789889, Length=246, Percent_Identity=29.6747967479675, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1787498, Length=216, Percent_Identity=29.1666666666667, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31769; Mature: 31638

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFDNVYREKKMPSPLLYTWRLFSSDGLAMVGFYGVLGLLLLCLLGSTLAPYTLDQQFLG
CCCHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCC
YQLLPPSWSRYGNVSFFLGTDDLGRDVLSRLLTGTASTYGSALLVTVAAALCAIVLGVFA
CCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GITRGLRSAILNHVLDTLLSIPSLLLAIIVVAFVGPSLEHAMFAVWLALLPRMVRTIYSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
VHDELDKEYVIAARLDGASTPHILAYAILPNIASVLVTEFTRALSMAILDIAALGFLDLG
HHHHHCHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AQLPSPEWGAMLGDSLDLVYVAPWTVMLPGGAILVSVLLVNLLGDGMRRAINAGVE
CCCCCCCHHHHHCCCCCEEEECCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PFDNVYREKKMPSPLLYTWRLFSSDGLAMVGFYGVLGLLLLCLLGSTLAPYTLDQQFLG
CCHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCC
YQLLPPSWSRYGNVSFFLGTDDLGRDVLSRLLTGTASTYGSALLVTVAAALCAIVLGVFA
CCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GITRGLRSAILNHVLDTLLSIPSLLLAIIVVAFVGPSLEHAMFAVWLALLPRMVRTIYSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
VHDELDKEYVIAARLDGASTPHILAYAILPNIASVLVTEFTRALSMAILDIAALGFLDLG
HHHHHCHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AQLPSPEWGAMLGDSLDLVYVAPWTVMLPGGAILVSVLLVNLLGDGMRRAINAGVE
CCCCCCCHHHHHCCCCCEEEECCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]