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The map label for this gene is sapD [H]

Identifier: 170024128

GI number: 170024128

Start: 2095581

End: 2096573

Strand: Reverse

Name: sapD [H]

Synonym: YPK_1889

Alternate gene names: 170024128

Gene position: 2096573-2095581 (Counterclockwise)

Preceding gene: 170024129

Following gene: 170024127

Centisome position: 44.71

GC content: 49.24

Gene sequence:

>993_bases
ATGCCATTACTTGATATTCGCAACCTTACCATCGAATTTATGACGTCAGAAGGGCCAGTAAAAGCCGTTGACCGCATCAG
CATGACCTTAACTGAGGGCGAAGTTCGTGGCTTAGTCGGTGAGTCTGGGTCCGGTAAAAGTTTGATAGCCAAAGCTATCT
GCGGTGTCAGCAAGGATAACTGGCGCATTACTGCTGACCGCTTTCGCTTTAACGACATTGATTTACTCCAACTGACTCCC
CGTCAGCGGCGTAAGGTGATCGGCCATAATATTTCTATGATTTTTCAGGAGCCGCAATCTTGCCTCGATCCATCAGAAAG
TATTGGCCTGCAACTGATACAAGCGATCCCTGGCTGGACATATAAAGGCCGCTGGTGGCAGCGTTTTCATTGGCGTAAAC
GGCGGGCAATCGAGTTATTGCATCGGGTTGGTATCAAAGATCACAAAGACATTATGCACAGTTACCCCTACGAGCTAACC
GAAGGTGAGTGTCAAAAGGTGATGATTGCTATCGCGCTGGCAAATCAGCCACGGTTGCTGATCGCCGATGAACCCACCAA
TGCGATGGAACCCACGACACAAGCACAGATTTTTCGCCTGTTGGCCCGGTTAAATCAGAATAACAACACCACGATTTTGT
TGATCAGTCACGATTTACAGATGATGAGTAAATGGGCAACCCGGGTTAACGTACTCTATTGTGGTCAGACGGTAGAAAGC
GCCGTCTGTGAAGACTTACTGTCTACCCCACATCACCCTTATACCCAAGCACTGATTCGTGCAATGCCTGATTTTGGCCG
ATCCCTGCCCCATAAAAGTCGCCTGAATACGTTGCCGGGTGCTATCCCATCGCTGGAACATTTACCGGTCGGTTGCCGTC
TTGGCCCACGTTGCCCTTACGCTCAGAAAACCTGTATTGAAACACCGCGCTTGCGGCTGGTGAAAAACCACGCCTTTGCC
TGTCATTTTCCCTTAAATCTGGAGGAGCAATAA

Upstream 100 bases:

>100_bases
GGACCGTGATGCTGCCAGGCGGCGCAATTTTGGTTAGTGTACTGTTGGTTAATCTGCTGGGTGATGGTATGCGCCGTGCC
ATTAATGCGGGGGTGGAATA

Downstream 100 bases:

>100_bases
TGGCCGAGACGTTGCTCGAAGTCCGTAATCTGAGCAAAACTTTCCGCTATCGTACCGGGCTGTTTCGCCGTCAACATGTT
GAGGCGGTAAAATCGGTGAG

Product: oligopeptide/dipeptide ABC transporter ATPase subunit

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MPLLDIRNLTIEFMTSEGPVKAVDRISMTLTEGEVRGLVGESGSGKSLIAKAICGVSKDNWRITADRFRFNDIDLLQLTP
RQRRKVIGHNISMIFQEPQSCLDPSESIGLQLIQAIPGWTYKGRWWQRFHWRKRRAIELLHRVGIKDHKDIMHSYPYELT
EGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLARLNQNNNTTILLISHDLQMMSKWATRVNVLYCGQTVES
AVCEDLLSTPHHPYTQALIRAMPDFGRSLPHKSRLNTLPGAIPSLEHLPVGCRLGPRCPYAQKTCIETPRLRLVKNHAFA
CHFPLNLEEQ

Sequences:

>Translated_330_residues
MPLLDIRNLTIEFMTSEGPVKAVDRISMTLTEGEVRGLVGESGSGKSLIAKAICGVSKDNWRITADRFRFNDIDLLQLTP
RQRRKVIGHNISMIFQEPQSCLDPSESIGLQLIQAIPGWTYKGRWWQRFHWRKRRAIELLHRVGIKDHKDIMHSYPYELT
EGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLARLNQNNNTTILLISHDLQMMSKWATRVNVLYCGQTVES
AVCEDLLSTPHHPYTQALIRAMPDFGRSLPHKSRLNTLPGAIPSLEHLPVGCRLGPRCPYAQKTCIETPRLRLVKNHAFA
CHFPLNLEEQ
>Mature_329_residues
PLLDIRNLTIEFMTSEGPVKAVDRISMTLTEGEVRGLVGESGSGKSLIAKAICGVSKDNWRITADRFRFNDIDLLQLTPR
QRRKVIGHNISMIFQEPQSCLDPSESIGLQLIQAIPGWTYKGRWWQRFHWRKRRAIELLHRVGIKDHKDIMHSYPYELTE
GECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLARLNQNNNTTILLISHDLQMMSKWATRVNVLYCGQTVESA
VCEDLLSTPHHPYTQALIRAMPDFGRSLPHKSRLNTLPGAIPSLEHLPVGCRLGPRCPYAQKTCIETPRLRLVKNHAFAC
HFPLNLEEQ

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4170

COG function: function code V; ABC-type antimicrobial peptide transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787548, Length=330, Percent_Identity=81.2121212121212, Blast_Score=581, Evalue=1e-167,
Organism=Escherichia coli, GI1789963, Length=328, Percent_Identity=42.3780487804878, Blast_Score=277, Evalue=6e-76,
Organism=Escherichia coli, GI1787759, Length=328, Percent_Identity=37.8048780487805, Blast_Score=213, Evalue=1e-56,
Organism=Escherichia coli, GI48994883, Length=309, Percent_Identity=37.8640776699029, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI145693107, Length=338, Percent_Identity=34.3195266272189, Blast_Score=175, Evalue=3e-45,
Organism=Escherichia coli, GI1787500, Length=329, Percent_Identity=35.258358662614, Blast_Score=174, Evalue=6e-45,
Organism=Escherichia coli, GI1788506, Length=264, Percent_Identity=37.8787878787879, Blast_Score=161, Evalue=6e-41,
Organism=Escherichia coli, GI1789962, Length=313, Percent_Identity=31.3099041533546, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1787758, Length=313, Percent_Identity=31.9488817891374, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1787547, Length=276, Percent_Identity=29.3478260869565, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1789890, Length=258, Percent_Identity=29.8449612403101, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI48994997, Length=265, Percent_Identity=29.4339622641509, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1786398, Length=278, Percent_Identity=28.0575539568345, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1789891, Length=231, Percent_Identity=30.7359307359307, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1789032, Length=247, Percent_Identity=26.3157894736842, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787029, Length=249, Percent_Identity=26.5060240963855, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87081834, Length=231, Percent_Identity=29.4372294372294, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789873, Length=225, Percent_Identity=30.2222222222222, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI87081791, Length=268, Percent_Identity=24.6268656716418, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788450, Length=252, Percent_Identity=28.1746031746032, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790162, Length=260, Percent_Identity=23.8461538461538, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787089, Length=231, Percent_Identity=29.004329004329, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787712, Length=242, Percent_Identity=26.8595041322314, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787105, Length=239, Percent_Identity=27.6150627615063, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788225, Length=260, Percent_Identity=25.3846153846154, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789672, Length=243, Percent_Identity=27.9835390946502, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1790544, Length=224, Percent_Identity=27.6785714285714, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786872, Length=214, Percent_Identity=29.4392523364486, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786253, Length=227, Percent_Identity=28.1938325991189, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788644, Length=129, Percent_Identity=30.2325581395349, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1790525, Length=283, Percent_Identity=26.8551236749117, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789864, Length=256, Percent_Identity=25, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI48995001, Length=228, Percent_Identity=26.7543859649123, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787370, Length=253, Percent_Identity=20.5533596837945, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787112, Length=250, Percent_Identity=25.6, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593
- InterPro:   IPR010066
- InterPro:   IPR013563 [H]

Pfam domain/function: PF00005 ABC_tran; PF08352 oligo_HPY [H]

EC number: NA

Molecular weight: Translated: 37571; Mature: 37440

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLDIRNLTIEFMTSEGPVKAVDRISMTLTEGEVRGLVGESGSGKSLIAKAICGVSKDN
CCCCCCCCCEEEEEECCCCHHHHHHEEEEEECCHHHHCCCCCCCCHHHHHHHHHCCCCCC
WRITADRFRFNDIDLLQLTPRQRRKVIGHNISMIFQEPQSCLDPSESIGLQLIQAIPGWT
EEEEECCEECCCCEEEEECCHHHHHHHCCCHHHEEECCHHHCCCCHHHHHHHHHHCCCCC
YKGRWWQRFHWRKRRAIELLHRVGIKDHKDIMHSYPYELTEGECQKVMIAIALANQPRLL
CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHEEEEEEEECCCCEEE
IADEPTNAMEPTTQAQIFRLLARLNQNNNTTILLISHDLQMMSKWATRVNVLYCGQTVES
EEECCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHEEEEEECCHHHH
AVCEDLLSTPHHPYTQALIRAMPDFGRSLPHKSRLNTLPGAIPSLEHLPVGCRLGPRCPY
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCHHCCCCCCCCCCCCCC
AQKTCIETPRLRLVKNHAFACHFPLNLEEQ
CHHHHCCCCHHEEEECCEEEEEECCCCCCC
>Mature Secondary Structure 
PLLDIRNLTIEFMTSEGPVKAVDRISMTLTEGEVRGLVGESGSGKSLIAKAICGVSKDN
CCCCCCCCEEEEEECCCCHHHHHHEEEEEECCHHHHCCCCCCCCHHHHHHHHHCCCCCC
WRITADRFRFNDIDLLQLTPRQRRKVIGHNISMIFQEPQSCLDPSESIGLQLIQAIPGWT
EEEEECCEECCCCEEEEECCHHHHHHHCCCHHHEEECCHHHCCCCHHHHHHHHHHCCCCC
YKGRWWQRFHWRKRRAIELLHRVGIKDHKDIMHSYPYELTEGECQKVMIAIALANQPRLL
CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHEEEEEEEECCCCEEE
IADEPTNAMEPTTQAQIFRLLARLNQNNNTTILLISHDLQMMSKWATRVNVLYCGQTVES
EEECCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHEEEEEECCHHHH
AVCEDLLSTPHHPYTQALIRAMPDFGRSLPHKSRLNTLPGAIPSLEHLPVGCRLGPRCPY
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCHHCCCCCCCCCCCCCC
AQKTCIETPRLRLVKNHAFACHFPLNLEEQ
CHHHHCCCCHHEEEECCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]