Click here to switch to the map view.

The map label for this gene is fklB [C]

Identifier: 169629645

GI number: 169629645

Start: 2604599

End: 2605189

Strand: Reverse

Name: fklB [C]

Synonym: MAB_2559c

Alternate gene names: 169629645

Gene position: 2605189-2604599 (Counterclockwise)

Preceding gene: 169629647

Following gene: 169629643

Centisome position: 51.41

GC content: 68.87

Gene sequence:

>591_bases
GTGAACCTCTTCCGCGTCTCACCGTCCGCCACACTTGCGGCCTGTACAGCCTCATTCGTCATGGCACTCGCGGCGTGCGG
ATCCGACACGGAGGCAAACTCGGCGCCAGCCGACCCGCCGAGCACAGCCAGCGGGTGCCCCACCGCGGCCCCGCAAGCCG
GCGGTACGCCCGAGTGGACGCTGGCGGGGGCCACCGGCAGCGTTGCTGTCACTGGATCCACGGACGCGGCGGCGCCCGCG
ATCACCGTGACCGCGCCGTTCAGTGTGGCCGAGACCCAGGTACATACGTTGCAGGCCGGCTCGGGACCGATCGTCGGCGA
CCTGGCCACGGTCTCGGTCTGCTACATGGGTGTCAATGGACGCGATGGCTCCGTGTTCGACAGCAGCTACACACGCGGTA
CGCCCGCGCAGTTCCCGCTCGGCGGCGTCGTACCCGGCTTCAAGAAGGCCATCGCCGGACAACGGGTCGGGTCGACCGTC
GCTGTGGCAATGACCTCCGCCGACGGCTATCCCGCAGGTCAGCCCAGCGCTGGGATCCGTGCCGGCGACACCCTTGTCTT
CGCGATCAAGGTCCTCAACGCCACGAACTGA

Upstream 100 bases:

>100_bases
GTCTGAGCACTTCGCGAAGGCTGGCGGTCATCGAGAGAAGCAGCGTTCCCAGGTGTCACTGCAGGAATGACCACACACCG
CAGCTGTTAGCGTAACGACC

Downstream 100 bases:

>100_bases
TCCGCTGGGGCGGATTTCAGCACGCGGTTGACTAACCCGGATTGTTCTAGTCCTAGTTGAAATCTGTTGTTGCTGTTGCT
ATTTCAGAGATCACGTCCTT

Product: peptidyl-prolyl cis-trans isomerase

Products: peptidylproline (Omega=0) [C]

Alternate protein names: Peptidyl-Prolyl Cis-Trans Isomerase; Secreted Peptidyl-Prolyl Cis-Trans Isomerase; Peptidyl-Prolyl Cis-Trans Isomerase FKBP-Type; FKBP-Type Peptidyl-Prolyl Cis-Trans Isomerase; Peptidylprolyl Isomerase; FKBP-Type Peptidylprolyl Isomerase; Peptidylprolyl Isomerase FKBP Family Protein

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MNLFRVSPSATLAACTASFVMALAACGSDTEANSAPADPPSTASGCPTAAPQAGGTPEWTLAGATGSVAVTGSTDAAAPA
ITVTAPFSVAETQVHTLQAGSGPIVGDLATVSVCYMGVNGRDGSVFDSSYTRGTPAQFPLGGVVPGFKKAIAGQRVGSTV
AVAMTSADGYPAGQPSAGIRAGDTLVFAIKVLNATN

Sequences:

>Translated_196_residues
MNLFRVSPSATLAACTASFVMALAACGSDTEANSAPADPPSTASGCPTAAPQAGGTPEWTLAGATGSVAVTGSTDAAAPA
ITVTAPFSVAETQVHTLQAGSGPIVGDLATVSVCYMGVNGRDGSVFDSSYTRGTPAQFPLGGVVPGFKKAIAGQRVGSTV
AVAMTSADGYPAGQPSAGIRAGDTLVFAIKVLNATN
>Mature_196_residues
MNLFRVSPSATLAACTASFVMALAACGSDTEANSAPADPPSTASGCPTAAPQAGGTPEWTLAGATGSVAVTGSTDAAAPA
ITVTAPFSVAETQVHTLQAGSGPIVGDLATVSVCYMGVNGRDGSVFDSSYTRGTPAQFPLGGVVPGFKKAIAGQRVGSTV
AVAMTSADGYPAGQPSAGIRAGDTLVFAIKVLNATN

Specific function: Ppiases Accelerate The Folding Of Proteins. It Catalyzes The Cis-Trans Isomerization Of Proline Imidic Peptide Bonds In Oligopeptides. [C]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Cytoplasm And Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 5.2.1.8 [C]

Molecular weight: Translated: 19097; Mature: 19097

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLFRVSPSATLAACTASFVMALAACGSDTEANSAPADPPSTASGCPTAAPQAGGTPEWT
CCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
LAGATGSVAVTGSTDAAAPAITVTAPFSVAETQVHTLQAGSGPIVGDLATVSVCYMGVNG
EECCCCCEEEECCCCCCCCEEEEECCCCCCHHEEEEEECCCCCEEEHHHEEEEEEECCCC
RDGSVFDSSYTRGTPAQFPLGGVVPGFKKAIAGQRVGSTVAVAMTSADGYPAGQPSAGIR
CCCCEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCC
AGDTLVFAIKVLNATN
CCCEEEEEEEEECCCC
>Mature Secondary Structure
MNLFRVSPSATLAACTASFVMALAACGSDTEANSAPADPPSTASGCPTAAPQAGGTPEWT
CCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
LAGATGSVAVTGSTDAAAPAITVTAPFSVAETQVHTLQAGSGPIVGDLATVSVCYMGVNG
EECCCCCEEEECCCCCCCCEEEEECCCCCCHHEEEEEECCCCCEEEHHHEEEEEEECCCC
RDGSVFDSSYTRGTPAQFPLGGVVPGFKKAIAGQRVGSTVAVAMTSADGYPAGQPSAGIR
CCCCEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCC
AGDTLVFAIKVLNATN
CCCEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Peptidoproline (Omega=180) [C]

Specific reaction: Peptidoproline (Omega=180) = peptidylproline (omega=0) [C]

General reaction: Rotation (Single bond) [C]

Inhibitor: cyclosporins [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA