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The map label for this gene is pckG [H]

Identifier: 169629647

GI number: 169629647

Start: 2605977

End: 2607842

Strand: Reverse

Name: pckG [H]

Synonym: MAB_2561c

Alternate gene names: 169629647

Gene position: 2607842-2605977 (Counterclockwise)

Preceding gene: 169629648

Following gene: 169629645

Centisome position: 51.47

GC content: 63.24

Gene sequence:

>1866_bases
GTGGCAAGTTCGGTGGAAATGACCGGTGCGGCACAGGCAGTGCCAGGATTGGCGCCCGCGCCAACCACCCACGCCGGGGT
GTTGTTGTGGGTGGCCGAGATGGCCGAACTATTGGAACCGGACAAGGTGGTGTGGTGCGACGGATCGCGCGCTGAATGGG
ATCGGTTGACCAAGCAGCTCGTCGCCAAGGGCACCTTTGTGCCGCTGACAGGCAAGCCGAATTCGTTTTGGGCCGTTTCT
GACCCGGCGGATGTGGCACGGGTAGAAGACCGCACGTTCATCTGCTCCGACGACGCGTCCGATGCTGGGCCGACCAACAA
CTGGATGGACCCGGTCGACATGACCACGATCATGACCGAGGAATATCGCGGTGCGATGGCAGGCCGCACGATGTACGTGA
TCGCGTTCTGCATGGGCCCGCTGGGTTCAGATGACCCGAAATTCGGGGTACAGATTACTGATTCGGAGTACGTGGCCGTC
TCGATGCAGATCATGACGCGCTCCGGCTCGCACGTCTGGGACCGTCTCGGGCTGCGCGGCCGGTTCGTCAAATGCGTGCA
CTCGGTGGGTGCTCCGCTTGCGCCGGGACAATCTGATGTGCCCTGGCCGTGTGATGCAACCAAGTACATTTCGCATTTCC
CCTCCACCCGCACCATCTGGAGTTATGGGTCCGGATACGGCGGGAATGCCTTGTTGGGCAAGAAGTGTTTCGCCCTGCGC
ATCGCATCGGTGATGGCGCGCGATGAGGGCTGGCTCGCCGAGCACATGCTGATCCTCAAGCTCACCTCCCCCGAGGGTGC
CGCGAAGTACGTGGCCGCAGCATTTCCGTCCTCGTGCGGCAAGACCAACATGGCGATGCTGCAACCCGCGCTACCGGGCT
GGACGGCCGAAACGATCGGCGACGACATCGCCTGGATACGTTTCGGGGCCGATGGGCGCCTGTACGCGGTCAACCCAGAA
GCCGGGTTCTTCGGGGTGGCGCCGGGCACCGGAAAGAGCACCAACCCGAACGCCATGGACACCATCGAGCTCGGCAACTC
GATCTTCACCAACACCGCGCTGACCGATGATGGGGACGTGTGGTGGGAAGGAATGACCAAGACACCGCCGGAACATCTGA
TCGACTGGCAAGGCCGGCAGTGGACTCCGGAGTCGACTGAGCCTGCGGCACATCCGAATTCACGGTACTGCACACCCATT
GCGCAGTGCCCGACCGTCGCACCCGAGTGGGATGACCCCACCGGGGTACCCATCTCGGCGATCTTCTTCGGCGGCCGCCG
CGCCTCCACGGTGCCGCTGATCACCGAAGCCTTGAGCTGGCGTCACGGAGTGTTCTTGGCTTCCACCTTGTCCTCGGAAA
CCACCGCGGCCGCCGCGGGCGAAGTCGGGGTACTGCGCCGCGATCCCATGGCGATGCGCCCCTTCCTCGGATACCACGTG
GGTGACTACTTTCAGCACTGGCTCAATATCGGTACCCGCTCCGATCCAGACCTACTTCCGAAGATCTTCTACGTCAACTG
GTTTCGCCGCGATTCCGGCGGCAAGTTCTTGTGGCCCGGGTTCGGGGAGAACGCGCGCGTACTCAAATGGGCGCTTGATC
GCCTCGATGCCGCCACGGACGCGGTCGCTACCCCGATCGGCTTTGTGCCCACCTGCGACGCCCTGGACCGGACCGGCCTA
GATATCAGTGATCAGGATCTACACGCGGCGCTGGCCGTCAACATCGACGAATGGGTCACCGAAGCTGAATCGATCGACTA
CTGGTATGCCAGCATCGGCGGCAATCGGCTACCCGACGAACTGCGGGTCGAACTCGGTGCGCTACGAATGCGGCTGGCCG
AGGCACGGCAGACGAGCCGGCTATAG

Upstream 100 bases:

>100_bases
GTGTTGGGGCATCTCCGGCTAGCGCCCTCTAATTGCTTGTTTTCTTAATTAGCACGCTTTATTGGTAGTCGAGGTCCGTG
ATGAACGGTGAGGAGCAGTT

Downstream 100 bases:

>100_bases
GCCGGAGGGCACGACCTTGCCGTTGACCGTGACCGCTACCTCGCCGCTCTTCGCGTTGTACTCGATCTTGCCGTGCTCAA
AGGTCGACACGAGCTGATCA

Product: phosphoenolpyruvate carboxykinase

Products: NA

Alternate protein names: PEP carboxykinase; PEPCK; Phosphoenolpyruvate carboxylase [H]

Number of amino acids: Translated: 621; Mature: 620

Protein sequence:

>621_residues
MASSVEMTGAAQAVPGLAPAPTTHAGVLLWVAEMAELLEPDKVVWCDGSRAEWDRLTKQLVAKGTFVPLTGKPNSFWAVS
DPADVARVEDRTFICSDDASDAGPTNNWMDPVDMTTIMTEEYRGAMAGRTMYVIAFCMGPLGSDDPKFGVQITDSEYVAV
SMQIMTRSGSHVWDRLGLRGRFVKCVHSVGAPLAPGQSDVPWPCDATKYISHFPSTRTIWSYGSGYGGNALLGKKCFALR
IASVMARDEGWLAEHMLILKLTSPEGAAKYVAAAFPSSCGKTNMAMLQPALPGWTAETIGDDIAWIRFGADGRLYAVNPE
AGFFGVAPGTGKSTNPNAMDTIELGNSIFTNTALTDDGDVWWEGMTKTPPEHLIDWQGRQWTPESTEPAAHPNSRYCTPI
AQCPTVAPEWDDPTGVPISAIFFGGRRASTVPLITEALSWRHGVFLASTLSSETTAAAAGEVGVLRRDPMAMRPFLGYHV
GDYFQHWLNIGTRSDPDLLPKIFYVNWFRRDSGGKFLWPGFGENARVLKWALDRLDAATDAVATPIGFVPTCDALDRTGL
DISDQDLHAALAVNIDEWVTEAESIDYWYASIGGNRLPDELRVELGALRMRLAEARQTSRL

Sequences:

>Translated_621_residues
MASSVEMTGAAQAVPGLAPAPTTHAGVLLWVAEMAELLEPDKVVWCDGSRAEWDRLTKQLVAKGTFVPLTGKPNSFWAVS
DPADVARVEDRTFICSDDASDAGPTNNWMDPVDMTTIMTEEYRGAMAGRTMYVIAFCMGPLGSDDPKFGVQITDSEYVAV
SMQIMTRSGSHVWDRLGLRGRFVKCVHSVGAPLAPGQSDVPWPCDATKYISHFPSTRTIWSYGSGYGGNALLGKKCFALR
IASVMARDEGWLAEHMLILKLTSPEGAAKYVAAAFPSSCGKTNMAMLQPALPGWTAETIGDDIAWIRFGADGRLYAVNPE
AGFFGVAPGTGKSTNPNAMDTIELGNSIFTNTALTDDGDVWWEGMTKTPPEHLIDWQGRQWTPESTEPAAHPNSRYCTPI
AQCPTVAPEWDDPTGVPISAIFFGGRRASTVPLITEALSWRHGVFLASTLSSETTAAAAGEVGVLRRDPMAMRPFLGYHV
GDYFQHWLNIGTRSDPDLLPKIFYVNWFRRDSGGKFLWPGFGENARVLKWALDRLDAATDAVATPIGFVPTCDALDRTGL
DISDQDLHAALAVNIDEWVTEAESIDYWYASIGGNRLPDELRVELGALRMRLAEARQTSRL
>Mature_620_residues
ASSVEMTGAAQAVPGLAPAPTTHAGVLLWVAEMAELLEPDKVVWCDGSRAEWDRLTKQLVAKGTFVPLTGKPNSFWAVSD
PADVARVEDRTFICSDDASDAGPTNNWMDPVDMTTIMTEEYRGAMAGRTMYVIAFCMGPLGSDDPKFGVQITDSEYVAVS
MQIMTRSGSHVWDRLGLRGRFVKCVHSVGAPLAPGQSDVPWPCDATKYISHFPSTRTIWSYGSGYGGNALLGKKCFALRI
ASVMARDEGWLAEHMLILKLTSPEGAAKYVAAAFPSSCGKTNMAMLQPALPGWTAETIGDDIAWIRFGADGRLYAVNPEA
GFFGVAPGTGKSTNPNAMDTIELGNSIFTNTALTDDGDVWWEGMTKTPPEHLIDWQGRQWTPESTEPAAHPNSRYCTPIA
QCPTVAPEWDDPTGVPISAIFFGGRRASTVPLITEALSWRHGVFLASTLSSETTAAAAGEVGVLRRDPMAMRPFLGYHVG
DYFQHWLNIGTRSDPDLLPKIFYVNWFRRDSGGKFLWPGFGENARVLKWALDRLDAATDAVATPIGFVPTCDALDRTGLD
ISDQDLHAALAVNIDEWVTEAESIDYWYASIGGNRLPDELRVELGALRMRLAEARQTSRL

Specific function: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle [H]

COG id: COG1274

COG function: function code C; Phosphoenolpyruvate carboxykinase (GTP)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family [H]

Homologues:

Organism=Homo sapiens, GI66346721, Length=602, Percent_Identity=51.4950166112957, Blast_Score=594, Evalue=1e-170,
Organism=Homo sapiens, GI187281517, Length=593, Percent_Identity=49.5784148397976, Blast_Score=591, Evalue=1e-169,
Organism=Homo sapiens, GI66346723, Length=371, Percent_Identity=53.099730458221, Blast_Score=372, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI71989645, Length=603, Percent_Identity=48.7562189054726, Blast_Score=578, Evalue=1e-165,
Organism=Caenorhabditis elegans, GI71989658, Length=603, Percent_Identity=48.7562189054726, Blast_Score=577, Evalue=1e-165,
Organism=Caenorhabditis elegans, GI71989653, Length=590, Percent_Identity=48.6440677966102, Blast_Score=565, Evalue=1e-161,
Organism=Caenorhabditis elegans, GI17555492, Length=612, Percent_Identity=46.4052287581699, Blast_Score=553, Evalue=1e-157,
Organism=Caenorhabditis elegans, GI32564411, Length=550, Percent_Identity=48.3636363636364, Blast_Score=536, Evalue=1e-152,
Organism=Caenorhabditis elegans, GI32564407, Length=523, Percent_Identity=48.3747609942639, Blast_Score=498, Evalue=1e-141,
Organism=Caenorhabditis elegans, GI71989649, Length=504, Percent_Identity=50.1984126984127, Blast_Score=497, Evalue=1e-141,
Organism=Caenorhabditis elegans, GI32564409, Length=369, Percent_Identity=47.1544715447154, Blast_Score=344, Evalue=7e-95,
Organism=Caenorhabditis elegans, GI17540956, Length=524, Percent_Identity=25.763358778626, Blast_Score=162, Evalue=6e-40,
Organism=Drosophila melanogaster, GI24655085, Length=600, Percent_Identity=50.1666666666667, Blast_Score=593, Evalue=1e-170,
Organism=Drosophila melanogaster, GI24655082, Length=601, Percent_Identity=50.0831946755408, Blast_Score=593, Evalue=1e-169,
Organism=Drosophila melanogaster, GI161077226, Length=568, Percent_Identity=51.056338028169, Blast_Score=572, Evalue=1e-163,
Organism=Drosophila melanogaster, GI24655088, Length=503, Percent_Identity=51.4910536779324, Blast_Score=523, Evalue=1e-148,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018091
- InterPro:   IPR013035
- InterPro:   IPR008209
- InterPro:   IPR008210 [H]

Pfam domain/function: PF00821 PEPCK [H]

EC number: =4.1.1.32 [H]

Molecular weight: Translated: 67643; Mature: 67512

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASSVEMTGAAQAVPGLAPAPTTHAGVLLWVAEMAELLEPDKVVWCDGSRAEWDRLTKQL
CCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHH
VAKGTFVPLTGKPNSFWAVSDPADVARVEDRTFICSDDASDAGPTNNWMDPVDMTTIMTE
HHCCCEEEECCCCCCEEEECCCHHHHEECCCEEEECCCCCCCCCCCCCCCCCHHHHHHHH
EYRGAMAGRTMYVIAFCMGPLGSDDPKFGVQITDSEYVAVSMQIMTRSGSHVWDRLGLRG
HHHHHHCCCHHEEEEEHHCCCCCCCCCCCEEECCCCEEEEEEEEEECCCCHHHHHHCCCH
RFVKCVHSVGAPLAPGQSDVPWPCDATKYISHFPSTRTIWSYGSGYGGNALLGKKCFALR
HHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEECCCCCCCCCCHHHHHHHHHH
IASVMARDEGWLAEHMLILKLTSPEGAAKYVAAAFPSSCGKTNMAMLQPALPGWTAETIG
HHHHHHCCCCCCEEEEEEEEEECCCCHHHHHHHHCCCCCCCCCHHHCCCCCCCCCHHHCC
DDIAWIRFGADGRLYAVNPEAGFFGVAPGTGKSTNPNAMDTIELGNSIFTNTALTDDGDV
CCEEEEEECCCCEEEEECCCCCEEECCCCCCCCCCCCCCCHHHCCCCEEECCCCCCCCCE
WWEGMTKTPPEHLIDWQGRQWTPESTEPAAHPNSRYCTPIAQCPTVAPEWDDPTGVPISA
EECCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCEEEE
IFFGGRRASTVPLITEALSWRHGVFLASTLSSETTAAAAGEVGVLRRDPMAMRPFLGYHV
EEECCCCCCCCHHHHHHHHHHCCEEEEECCCCCHHHHHCCCCCEEECCCCHHHHHHHHHH
GDYFQHWLNIGTRSDPDLLPKIFYVNWFRRDSGGKFLWPGFGENARVLKWALDRLDAATD
HHHHHHHHHCCCCCCHHHHHHEEEEEEEEECCCCCEECCCCCCCHHHHHHHHHHHHHHHH
AVATPIGFVPTCDALDRTGLDISDQDLHAALAVNIDEWVTEAESIDYWYASIGGNRLPDE
HHHCCCCCCCCCCHHHCCCCCCCCCCCEEEEEEEHHHHHHHHHHCCEEEEECCCCCCCHH
LRVELGALRMRLAEARQTSRL
HHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ASSVEMTGAAQAVPGLAPAPTTHAGVLLWVAEMAELLEPDKVVWCDGSRAEWDRLTKQL
CCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHH
VAKGTFVPLTGKPNSFWAVSDPADVARVEDRTFICSDDASDAGPTNNWMDPVDMTTIMTE
HHCCCEEEECCCCCCEEEECCCHHHHEECCCEEEECCCCCCCCCCCCCCCCCHHHHHHHH
EYRGAMAGRTMYVIAFCMGPLGSDDPKFGVQITDSEYVAVSMQIMTRSGSHVWDRLGLRG
HHHHHHCCCHHEEEEEHHCCCCCCCCCCCEEECCCCEEEEEEEEEECCCCHHHHHHCCCH
RFVKCVHSVGAPLAPGQSDVPWPCDATKYISHFPSTRTIWSYGSGYGGNALLGKKCFALR
HHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEECCCCCCCCCCHHHHHHHHHH
IASVMARDEGWLAEHMLILKLTSPEGAAKYVAAAFPSSCGKTNMAMLQPALPGWTAETIG
HHHHHHCCCCCCEEEEEEEEEECCCCHHHHHHHHCCCCCCCCCHHHCCCCCCCCCHHHCC
DDIAWIRFGADGRLYAVNPEAGFFGVAPGTGKSTNPNAMDTIELGNSIFTNTALTDDGDV
CCEEEEEECCCCEEEEECCCCCEEECCCCCCCCCCCCCCCHHHCCCCEEECCCCCCCCCE
WWEGMTKTPPEHLIDWQGRQWTPESTEPAAHPNSRYCTPIAQCPTVAPEWDDPTGVPISA
EECCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCEEEE
IFFGGRRASTVPLITEALSWRHGVFLASTLSSETTAAAAGEVGVLRRDPMAMRPFLGYHV
EEECCCCCCCCHHHHHHHHHHCCEEEEECCCCCHHHHHCCCCCEEECCCCHHHHHHHHHH
GDYFQHWLNIGTRSDPDLLPKIFYVNWFRRDSGGKFLWPGFGENARVLKWALDRLDAATD
HHHHHHHHHCCCCCCHHHHHHEEEEEEEEECCCCCEECCCCCCCHHHHHHHHHHHHHHHH
AVATPIGFVPTCDALDRTGLDISDQDLHAALAVNIDEWVTEAESIDYWYASIGGNRLPDE
HHHCCCCCCCCCCHHHCCCCCCCCCCCEEEEEEEHHHHHHHHHHCCEEEEECCCCCCCHH
LRVELGALRMRLAEARQTSRL
HHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA