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The map label for this gene is cysU [H]

Identifier: 169628743

GI number: 169628743

Start: 1682589

End: 1683479

Strand: Direct

Name: cysU [H]

Synonym: MAB_1653

Alternate gene names: 169628743

Gene position: 1682589-1683479 (Clockwise)

Preceding gene: 169628742

Following gene: 169628744

Centisome position: 33.21

GC content: 63.52

Gene sequence:

>891_bases
ATGAGTACCGTGATCGAAAATCCCACCTCACAGGACAATCCGGAGGACAAGGTGCCACCGACGGGAGAGTCCGGCACGGC
CGTGGGCCGTTCGCGTAAGCGCTTCAGCGATGACCCGTTGCGCATCGGTGTGGCCAGCATCTGGTTGTCGGTGATCGTGC
TGCTGCCGTTGGCGGCCATTGTGTGGCAGTCCGCCGAGGGTGGGTGGGGCGCGTTCGTCAGCGCCGTCACCTCCAACTCG
GCACTGGCCTCGTTCAAGGTGACACTGCTGATCTCCATCGCGGTGGCAGTGCTCAATGGTCTGTTCGGGCTGTTGGTGGC
CTGGGTGCTGGTCCGGGACAATTTCCCGGGCAAGCGGATTGTGGACACGTTGATCGATCTGCCGTTCGCCCTGCCCACGA
TCGTGGCCAGTATCGTGCTGCTTGCCCTGTACGGTCCGAGCAGCCCGATCAATGTGCACTTGCAGCACACCAAGTGGGGC
GTCGGGATAGCTCTGCTGTTCGTGACGCTGCCGTTTGTGGTGCGGGCCGTGCAGCCGGTGCTGCTTGAGCTCGAACGAGA
GGTGGAAGAGGCCGCGGCCTCGCTGGGTGCCAGCAACCCGGTGATCTTCAGCAAGGTGATCCTGCCTGCGTTGCTGCCCT
CACTGCTGTCCGGTGTCGGGCTCGCATTCTCCAGGGCCATCGGTGAATTCGGTTCCGTGGTGCTGATCGGTGGCGCGGTG
CCGGGGGAGACCGAGGTGTCCTCGCAGTGGATCCGGACCCTCATCGAGAACGACGACCGGACCGGCGCGGCCGCCATCTC
CATTGTGTTGCTCGCCATTTCGTTTGTGGTGTTGTTCATCCTGCGCGGCCTGGGTTCACGCGCGGCCAAGCGAGAGGAAC
TTGATCGATGA

Upstream 100 bases:

>100_bases
TGTGGACCATCAAGGATTTGGGCGGATGGAAGAGCGTCGACAAGGAATTGTTCGACAAAAACGACGGATCCATCACCAAG
ATCTACAAAGAGGCGACCGG

Downstream 100 bases:

>100_bases
CGCTCTCTCCCGCGGTCAAGTACGCGCTGCGCATACTGGCGCTGCTCTACGTCGCCGTGCTGCTGATCGTGCCCCTGGGA
CTCATCCTGTGGCGTGCCTT

Product: sulfate ABC transporter, permease protein CysT

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MSTVIENPTSQDNPEDKVPPTGESGTAVGRSRKRFSDDPLRIGVASIWLSVIVLLPLAAIVWQSAEGGWGAFVSAVTSNS
ALASFKVTLLISIAVAVLNGLFGLLVAWVLVRDNFPGKRIVDTLIDLPFALPTIVASIVLLALYGPSSPINVHLQHTKWG
VGIALLFVTLPFVVRAVQPVLLELEREVEEAAASLGASNPVIFSKVILPALLPSLLSGVGLAFSRAIGEFGSVVLIGGAV
PGETEVSSQWIRTLIENDDRTGAAAISIVLLAISFVVLFILRGLGSRAAKREELDR

Sequences:

>Translated_296_residues
MSTVIENPTSQDNPEDKVPPTGESGTAVGRSRKRFSDDPLRIGVASIWLSVIVLLPLAAIVWQSAEGGWGAFVSAVTSNS
ALASFKVTLLISIAVAVLNGLFGLLVAWVLVRDNFPGKRIVDTLIDLPFALPTIVASIVLLALYGPSSPINVHLQHTKWG
VGIALLFVTLPFVVRAVQPVLLELEREVEEAAASLGASNPVIFSKVILPALLPSLLSGVGLAFSRAIGEFGSVVLIGGAV
PGETEVSSQWIRTLIENDDRTGAAAISIVLLAISFVVLFILRGLGSRAAKREELDR
>Mature_295_residues
STVIENPTSQDNPEDKVPPTGESGTAVGRSRKRFSDDPLRIGVASIWLSVIVLLPLAAIVWQSAEGGWGAFVSAVTSNSA
LASFKVTLLISIAVAVLNGLFGLLVAWVLVRDNFPGKRIVDTLIDLPFALPTIVASIVLLALYGPSSPINVHLQHTKWGV
GIALLFVTLPFVVRAVQPVLLELEREVEEAAASLGASNPVIFSKVILPALLPSLLSGVGLAFSRAIGEFGSVVLIGGAVP
GETEVSSQWIRTLIENDDRTGAAAISIVLLAISFVVLFILRGLGSRAAKREELDR

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0555

COG function: function code O; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788764, Length=238, Percent_Identity=42.436974789916, Blast_Score=180, Evalue=1e-46,
Organism=Escherichia coli, GI87082099, Length=274, Percent_Identity=32.1167883211679, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1786980, Length=212, Percent_Identity=33.9622641509434, Blast_Score=89, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011865
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31286; Mature: 31155

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVIENPTSQDNPEDKVPPTGESGTAVGRSRKRFSDDPLRIGVASIWLSVIVLLPLAAI
CCCCCCCCCCCCCCCCCCCCCCCCCCHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
VWQSAEGGWGAFVSAVTSNSALASFKVTLLISIAVAVLNGLFGLLVAWVLVRDNFPGKRI
HHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VDTLIDLPFALPTIVASIVLLALYGPSSPINVHLQHTKWGVGIALLFVTLPFVVRAVQPV
HHHHHHCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
LLELEREVEEAAASLGASNPVIFSKVILPALLPSLLSGVGLAFSRAIGEFGSVVLIGGAV
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
PGETEVSSQWIRTLIENDDRTGAAAISIVLLAISFVVLFILRGLGSRAAKREELDR
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCC
>Mature Secondary Structure 
STVIENPTSQDNPEDKVPPTGESGTAVGRSRKRFSDDPLRIGVASIWLSVIVLLPLAAI
CCCCCCCCCCCCCCCCCCCCCCCCCHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
VWQSAEGGWGAFVSAVTSNSALASFKVTLLISIAVAVLNGLFGLLVAWVLVRDNFPGKRI
HHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VDTLIDLPFALPTIVASIVLLALYGPSSPINVHLQHTKWGVGIALLFVTLPFVVRAVQPV
HHHHHHCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
LLELEREVEEAAASLGASNPVIFSKVILPALLPSLLSGVGLAFSRAIGEFGSVVLIGGAV
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
PGETEVSSQWIRTLIENDDRTGAAAISIVLLAISFVVLFILRGLGSRAAKREELDR
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2188958; 9205837; 9278503; 2188959 [H]