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The map label for this gene is cysW [H]

Identifier: 169628744

GI number: 169628744

Start: 1683476

End: 1684288

Strand: Direct

Name: cysW [H]

Synonym: MAB_1654

Alternate gene names: 169628744

Gene position: 1683476-1684288 (Clockwise)

Preceding gene: 169628743

Following gene: 169628745

Centisome position: 33.22

GC content: 62.98

Gene sequence:

>813_bases
ATGACGCTCTCTCCCGCGGTCAAGTACGCGCTGCGCATACTGGCGCTGCTCTACGTCGCCGTGCTGCTGATCGTGCCCCT
GGGACTCATCCTGTGGCGTGCCTTCGCGCCGGGCCTGGTCCAGTTCTGGGAGTACATCTCCACCCCGGCTGCGATTTCCG
CGTTCAACCTCTCCCTGCTGGTGGTCGCGATTGTGGTGCCGCTCAACGTGATCTTCGGGGTGCCGACGGCGTTGGTGCTG
GCCCGCAACAAGTTCCGTGGCAAGGGCGTTCTTCAGGCCATCATCGACCTGCCATTCGCGGTGTCGCCGGTCATCGTAGG
TGTGGCCCTGATCGTGCTGTGGGGCTCGGCGGGCCTGCTGGGATTCGTGGAGAACGACTGGAAGTTCAAGATCATCTTCG
GACTGCCGGGCATCGTGCTGGCGAGCATCTTCGTCACGCTGCCGTTCGTGATCCGTGAGGTCGAGCCGGTGTTGCATGAG
ATCGGCGACGATCAAGAACAGGCAGCCGCGACGCTGGGTGCCAATCCGTGGCAGACGTTCTGGCGCATCACCCTGCCGTC
CATTCGGTGGGGTCTCACCTACGGCATCGTGCTGACCGTCGCCCGCACCCTGGGTGAGTACGGTGCGGTGATCATGGTGT
CCTCCGGCCTGCCGGGTAAGTCGCAAACGTTGACGCTATTGGTTTCCGATCGTCACCTGCGAGGTGACGAATACGGGGCG
TACGCGCTGTCTGTCGTGCTGATGGCGGTGGCTCTCATCGTCCTCGTCGTGCAGGTGGTTCTCGATCGCAACCGTGCCAA
GACCTCGAAATAG

Upstream 100 bases:

>100_bases
CGGCCGCCATCTCCATTGTGTTGCTCGCCATTTCGTTTGTGGTGTTGTTCATCCTGCGCGGCCTGGGTTCACGCGCGGCC
AAGCGAGAGGAACTTGATCG

Downstream 100 bases:

>100_bases
CCTGAGCTACCAAGGAGCTTCCTCATGACCGCTGAAAACACCATCACCGTTCGCGGTGCCAACAAGCATTACGGCGACTT
CGCCGCCCTGGACAATATCG

Product: sulfate ABC transporter, permease protein CysW

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MTLSPAVKYALRILALLYVAVLLIVPLGLILWRAFAPGLVQFWEYISTPAAISAFNLSLLVVAIVVPLNVIFGVPTALVL
ARNKFRGKGVLQAIIDLPFAVSPVIVGVALIVLWGSAGLLGFVENDWKFKIIFGLPGIVLASIFVTLPFVIREVEPVLHE
IGDDQEQAAATLGANPWQTFWRITLPSIRWGLTYGIVLTVARTLGEYGAVIMVSSGLPGKSQTLTLLVSDRHLRGDEYGA
YALSVVLMAVALIVLVVQVVLDRNRAKTSK

Sequences:

>Translated_270_residues
MTLSPAVKYALRILALLYVAVLLIVPLGLILWRAFAPGLVQFWEYISTPAAISAFNLSLLVVAIVVPLNVIFGVPTALVL
ARNKFRGKGVLQAIIDLPFAVSPVIVGVALIVLWGSAGLLGFVENDWKFKIIFGLPGIVLASIFVTLPFVIREVEPVLHE
IGDDQEQAAATLGANPWQTFWRITLPSIRWGLTYGIVLTVARTLGEYGAVIMVSSGLPGKSQTLTLLVSDRHLRGDEYGA
YALSVVLMAVALIVLVVQVVLDRNRAKTSK
>Mature_269_residues
TLSPAVKYALRILALLYVAVLLIVPLGLILWRAFAPGLVQFWEYISTPAAISAFNLSLLVVAIVVPLNVIFGVPTALVLA
RNKFRGKGVLQAIIDLPFAVSPVIVGVALIVLWGSAGLLGFVENDWKFKIIFGLPGIVLASIFVTLPFVIREVEPVLHEI
GDDQEQAAATLGANPWQTFWRITLPSIRWGLTYGIVLTVARTLGEYGAVIMVSSGLPGKSQTLTLLVSDRHLRGDEYGAY
ALSVVLMAVALIVLVVQVVLDRNRAKTSK

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4208

COG function: function code P; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082099, Length=266, Percent_Identity=37.218045112782, Blast_Score=179, Evalue=1e-46,
Organism=Escherichia coli, GI1788764, Length=207, Percent_Identity=35.2657004830918, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1786980, Length=218, Percent_Identity=36.2385321100917, Blast_Score=101, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011866
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29209; Mature: 29078

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSPAVKYALRILALLYVAVLLIVPLGLILWRAFAPGLVQFWEYISTPAAISAFNLSLL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHHH
VVAIVVPLNVIFGVPTALVLARNKFRGKGVLQAIIDLPFAVSPVIVGVALIVLWGSAGLL
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCE
GFVENDWKFKIIFGLPGIVLASIFVTLPFVIREVEPVLHEIGDDQEQAAATLGANPWQTF
EEEECCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHH
WRITLPSIRWGLTYGIVLTVARTLGEYGAVIMVSSGLPGKSQTLTLLVSDRHLRGDEYGA
HHEECCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEEEECCCCCCCCHHH
YALSVVLMAVALIVLVVQVVLDRNRAKTSK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TLSPAVKYALRILALLYVAVLLIVPLGLILWRAFAPGLVQFWEYISTPAAISAFNLSLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHHH
VVAIVVPLNVIFGVPTALVLARNKFRGKGVLQAIIDLPFAVSPVIVGVALIVLWGSAGLL
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCE
GFVENDWKFKIIFGLPGIVLASIFVTLPFVIREVEPVLHEIGDDQEQAAATLGANPWQTF
EEEECCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHH
WRITLPSIRWGLTYGIVLTVARTLGEYGAVIMVSSGLPGKSQTLTLLVSDRHLRGDEYGA
HHEECCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEEEECCCCCCCCHHH
YALSVVLMAVALIVLVVQVVLDRNRAKTSK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1708375 [H]