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The map label for this gene is ydjN [C]

Identifier: 169824204

GI number: 169824204

Start: 572929

End: 574215

Strand: Direct

Name: ydjN [C]

Synonym: FMG_0507

Alternate gene names: 169824204

Gene position: 572929-574215 (Clockwise)

Preceding gene: 169824203

Following gene: 169824205

Centisome position: 31.87

GC content: 34.42

Gene sequence:

>1287_bases
ATGAAATTCGTAGCATTAGCAGTTACTTTAGTATTGTTTGCTTTATTGATGTTCATGGCTAAGAAGAAAATGAATTTTGG
TACAAGAACAATTGTAGCTGCAATTTTAGGTATAATAGTAGGATTTATTTTTAAAGGAAACACAGAATATGTAAAAGTAT
TTGGATCTATCTATGCAAATTTATTATTTGCAATAGTAATTCCATTATTATTTACATCAATAGTTAGCACTGTAGTTTCT
TTGGAAAGTATAGAAAAAATGAAAAAAATTGGAACAAAAACAATCGGTATATTGAGTTTACACAATGTCTTAGGTTCACT
TGTAGGTTTGATTTTAGGGGTAGCATTCAAAATTGGACAAGGAAGTTCATTGACTTTGGCAGCTGATGCAAAAGCTAAGG
AAGTTCCAACTTTTGCAGAAACTTTTGTAAATTTCTTCCCAGATAATGTTTTAGGAAATGCAGCAGAAGCAAAAGTTGTT
CCTATAATTATTTTCTCTGTTCTTTTGGGATTGGCGATTTTACAATTAGAAGAAAGAGGAGAAGGAGAAAGAGCAAAACC
ATTTTTAAGTTTTATCGATTCAGCTGCGGCAGTGATTTTTAGATTTACCGGAATGATTATAGATTTTACTCCATACGCAG
TATTGGCTTTGATGGCAAACGCGGTTAGTAGAACTGATATGGCTAGTATGATGCCATTGATAGTTGTGTTGATATTAACT
TATGTTGCATCTATTTTCCACTCTTATATTACAACTAGTGCTCTTTTGGCGATATTTGCAAAAGTAAATCCAGTAAAATT
CTTCAAAAAATTCTGGCCAGTTCAATTGATTGCATTCTCAACACAATCATCAGTTGGATGTATTCCAGCAAATACTGAAA
ATTTAAGAGACAAATTGGGTGTTTCTGAAAAGATAGCAACTTTTGTTGCTTCGACCGGTTCAACTGTTGGTATGCCAGGT
TGTGCAGGATTCTGGCCTGTATTGTCAGCTATTTTGACAATTAATGTTATGGGAATTCATTATTCATTTGGACAATATGT
GATGCTTGTATTAGTAGCATTAGCAGTGTCATTGGGTACTGTTGGAGTTCCAGGAACTGCAACAATTACTACTACAGCAG
TATTCGCAGCAATGGGACTTCCCGTTGAAATGGTTGTATTGATGAGCCCTATTTCAATGCTTGCAGATATGGGTAGAACT
GCTACAAATGTTACAGCAGCAGGTTCTTCAGCAGTTATAGTTGCAGCAAGCGAAGGCGAATTAGACAGGGAAGTTTTTAA
TTCATAA

Upstream 100 bases:

>100_bases
CATAGTGAATTAAATAAAATTTACAAAAGTTAAAATTAAATTTGAAAATTGTGCTCAATATACTATAATATATAACTATA
AAATAAAAAGAGGTGTTTAG

Downstream 100 bases:

>100_bases
TTTTTACAAGAAATTTTATAATACTACAACAAATTATAGACCTTTACACATTTATTGATTCGTATTATAATCAAATTAGT
AAAAATTAGAAAGGATCGTT

Product: proton/sodium-glutamate symporter

Products: NA

Alternate protein names: Transporter of cystine tcyP [H]

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MKFVALAVTLVLFALLMFMAKKKMNFGTRTIVAAILGIIVGFIFKGNTEYVKVFGSIYANLLFAIVIPLLFTSIVSTVVS
LESIEKMKKIGTKTIGILSLHNVLGSLVGLILGVAFKIGQGSSLTLAADAKAKEVPTFAETFVNFFPDNVLGNAAEAKVV
PIIIFSVLLGLAILQLEERGEGERAKPFLSFIDSAAAVIFRFTGMIIDFTPYAVLALMANAVSRTDMASMMPLIVVLILT
YVASIFHSYITTSALLAIFAKVNPVKFFKKFWPVQLIAFSTQSSVGCIPANTENLRDKLGVSEKIATFVASTGSTVGMPG
CAGFWPVLSAILTINVMGIHYSFGQYVMLVLVALAVSLGTVGVPGTATITTTAVFAAMGLPVEMVVLMSPISMLADMGRT
ATNVTAAGSSAVIVAASEGELDREVFNS

Sequences:

>Translated_428_residues
MKFVALAVTLVLFALLMFMAKKKMNFGTRTIVAAILGIIVGFIFKGNTEYVKVFGSIYANLLFAIVIPLLFTSIVSTVVS
LESIEKMKKIGTKTIGILSLHNVLGSLVGLILGVAFKIGQGSSLTLAADAKAKEVPTFAETFVNFFPDNVLGNAAEAKVV
PIIIFSVLLGLAILQLEERGEGERAKPFLSFIDSAAAVIFRFTGMIIDFTPYAVLALMANAVSRTDMASMMPLIVVLILT
YVASIFHSYITTSALLAIFAKVNPVKFFKKFWPVQLIAFSTQSSVGCIPANTENLRDKLGVSEKIATFVASTGSTVGMPG
CAGFWPVLSAILTINVMGIHYSFGQYVMLVLVALAVSLGTVGVPGTATITTTAVFAAMGLPVEMVVLMSPISMLADMGRT
ATNVTAAGSSAVIVAASEGELDREVFNS
>Mature_428_residues
MKFVALAVTLVLFALLMFMAKKKMNFGTRTIVAAILGIIVGFIFKGNTEYVKVFGSIYANLLFAIVIPLLFTSIVSTVVS
LESIEKMKKIGTKTIGILSLHNVLGSLVGLILGVAFKIGQGSSLTLAADAKAKEVPTFAETFVNFFPDNVLGNAAEAKVV
PIIIFSVLLGLAILQLEERGEGERAKPFLSFIDSAAAVIFRFTGMIIDFTPYAVLALMANAVSRTDMASMMPLIVVLILT
YVASIFHSYITTSALLAIFAKVNPVKFFKKFWPVQLIAFSTQSSVGCIPANTENLRDKLGVSEKIATFVASTGSTVGMPG
CAGFWPVLSAILTINVMGIHYSFGQYVMLVLVALAVSLGTVGVPGTATITTTAVFAAMGLPVEMVVLMSPISMLADMGRT
ATNVTAAGSSAVIVAASEGELDREVFNS

Specific function: Mediates uptake of L-cystine, the oxidized form of L- cysteine [H]

COG id: COG1301

COG function: function code C; Na+/H+-dicarboxylate symporters

Gene ontology:

Cell location: Membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI169790839, Length=467, Percent_Identity=25.0535331905782, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI4827012, Length=293, Percent_Identity=29.6928327645051, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI40254478, Length=439, Percent_Identity=21.8678815489749, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI21314632, Length=401, Percent_Identity=22.9426433915212, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI66773030, Length=270, Percent_Identity=24.8148148148148, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI194239697, Length=266, Percent_Identity=24.4360902255639, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI262359914, Length=382, Percent_Identity=23.2984293193717, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI223468564, Length=245, Percent_Identity=22.8571428571429, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI5032093, Length=374, Percent_Identity=21.9251336898396, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI223468566, Length=245, Percent_Identity=22.8571428571429, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1788024, Length=403, Percent_Identity=31.7617866004963, Blast_Score=172, Evalue=5e-44,
Organism=Escherichia coli, GI1790514, Length=428, Percent_Identity=25, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1789947, Length=417, Percent_Identity=23.021582733813, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71983106, Length=450, Percent_Identity=23.5555555555556, Blast_Score=117, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI71983099, Length=450, Percent_Identity=23.5555555555556, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71996953, Length=458, Percent_Identity=22.4890829694323, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI193206505, Length=432, Percent_Identity=23.3796296296296, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17537407, Length=418, Percent_Identity=23.9234449760766, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI193206654, Length=402, Percent_Identity=20.3980099502488, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17541374, Length=403, Percent_Identity=22.0843672456576, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24583025, Length=431, Percent_Identity=23.2018561484919, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI17137668, Length=431, Percent_Identity=23.2018561484919, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24583023, Length=431, Percent_Identity=23.2018561484919, Blast_Score=101, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 45349; Mature: 45349

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFVALAVTLVLFALLMFMAKKKMNFGTRTIVAAILGIIVGFIFKGNTEYVKVFGSIYAN
CHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LLFAIVIPLLFTSIVSTVVSLESIEKMKKIGTKTIGILSLHNVLGSLVGLILGVAFKIGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GSSLTLAADAKAKEVPTFAETFVNFFPDNVLGNAAEAKVVPIIIFSVLLGLAILQLEERG
CCCEEEEECCCHHCCCHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
EGERAKPFLSFIDSAAAVIFRFTGMIIDFTPYAVLALMANAVSRTDMASMMPLIVVLILT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YVASIFHSYITTSALLAIFAKVNPVKFFKKFWPVQLIAFSTQSSVGCIPANTENLRDKLG
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHEEEEECCCCCCCCCCCHHHHHHHHC
VSEKIATFVASTGSTVGMPGCAGFWPVLSAILTINVMGIHYSFGQYVMLVLVALAVSLGT
CHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHCC
VGVPGTATITTTAVFAAMGLPVEMVVLMSPISMLADMGRTATNVTAAGSSAVIVAASEGE
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCEEEEEECCCC
LDREVFNS
HHHHHHCC
>Mature Secondary Structure
MKFVALAVTLVLFALLMFMAKKKMNFGTRTIVAAILGIIVGFIFKGNTEYVKVFGSIYAN
CHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LLFAIVIPLLFTSIVSTVVSLESIEKMKKIGTKTIGILSLHNVLGSLVGLILGVAFKIGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GSSLTLAADAKAKEVPTFAETFVNFFPDNVLGNAAEAKVVPIIIFSVLLGLAILQLEERG
CCCEEEEECCCHHCCCHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
EGERAKPFLSFIDSAAAVIFRFTGMIIDFTPYAVLALMANAVSRTDMASMMPLIVVLILT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YVASIFHSYITTSALLAIFAKVNPVKFFKKFWPVQLIAFSTQSSVGCIPANTENLRDKLG
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHEEEEECCCCCCCCCCCHHHHHHHHC
VSEKIATFVASTGSTVGMPGCAGFWPVLSAILTINVMGIHYSFGQYVMLVLVALAVSLGT
CHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHCC
VGVPGTATITTTAVFAAMGLPVEMVVLMSPISMLADMGRTATNVTAAGSSAVIVAASEGE
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCEEEEEECCCC
LDREVFNS
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA