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The map label for this gene is lepB [H]

Identifier: 169824205

GI number: 169824205

Start: 574319

End: 574846

Strand: Direct

Name: lepB [H]

Synonym: FMG_0508

Alternate gene names: 169824205

Gene position: 574319-574846 (Clockwise)

Preceding gene: 169824204

Following gene: 169824207

Centisome position: 31.95

GC content: 30.68

Gene sequence:

>528_bases
ATGACAGAAAAAGCAAAATCTTTTTTTGAGTGGTTATTTGTAATAGGAATTGCGATTGTATTGGCATTACTGCTTAGAAA
TTTTGTTATTAGTACAACTCATGTTGAGGGAAATAGCATGAATCCTACAATTGAACAAGGAGATAGAATTTTCGTCAACA
GAATGGGAATTTTCAAAAACAAATTAAAAAGAGGTAATATTATAGAACTTCACGCACCGGATAAGTCTGGTCGCGATTAT
ATCAAAAGAATTGTAGCATTACCTGGAGATACTGTTGAATTAAAAAACAATAAAGTGTACGTTAATAATGAACAATTGAA
TGAAAATTATACTAGTAGTCAGACTACTCTTGTTTCTGGAGATAAAACAAAATGGGAATTAGGTGAAGATGAATATTTTG
TATTGGGGGATAATAGACTTCCTCGAGAATCAAATGATAGCAGAATATTCGGACCGATAAACAAGAAAGACATAGTAGGA
AGAGCTTTTTTGAGATATTTTCCATTTAATAAATTTGGTGTATTATAA

Upstream 100 bases:

>100_bases
TTACAAGAAATTTTATAATACTACAACAAATTATAGACCTTTACACATTTATTGATTCGTATTATAATCAAATTAGTAAA
AATTAGAAAGGATCGTTAAT

Downstream 100 bases:

>100_bases
GAAAAACTAATCTTGGACTTTCCAAGATTAGTTTTTTTAAATTTCTATTAATTTGAATTTTGTTGAATTGTTCCGCTTCT
ATATGCATCGATTAAACTTT

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MTEKAKSFFEWLFVIGIAIVLALLLRNFVISTTHVEGNSMNPTIEQGDRIFVNRMGIFKNKLKRGNIIELHAPDKSGRDY
IKRIVALPGDTVELKNNKVYVNNEQLNENYTSSQTTLVSGDKTKWELGEDEYFVLGDNRLPRESNDSRIFGPINKKDIVG
RAFLRYFPFNKFGVL

Sequences:

>Translated_175_residues
MTEKAKSFFEWLFVIGIAIVLALLLRNFVISTTHVEGNSMNPTIEQGDRIFVNRMGIFKNKLKRGNIIELHAPDKSGRDY
IKRIVALPGDTVELKNNKVYVNNEQLNENYTSSQTTLVSGDKTKWELGEDEYFVLGDNRLPRESNDSRIFGPINKKDIVG
RAFLRYFPFNKFGVL
>Mature_174_residues
TEKAKSFFEWLFVIGIAIVLALLLRNFVISTTHVEGNSMNPTIEQGDRIFVNRMGIFKNKLKRGNIIELHAPDKSGRDYI
KRIVALPGDTVELKNNKVYVNNEQLNENYTSSQTTLVSGDKTKWELGEDEYFVLGDNRLPRESNDSRIFGPINKKDIVGR
AFLRYFPFNKFGVL

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 20076; Mature: 19945

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS00760 SPASE_I_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEKAKSFFEWLFVIGIAIVLALLLRNFVISTTHVEGNSMNPTIEQGDRIFVNRMGIFKN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHCCCEEEEEHHHHHHH
KLKRGNIIELHAPDKSGRDYIKRIVALPGDTVELKNNKVYVNNEQLNENYTSSQTTLVSG
HHCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEEECCEEEEECCCCCCCCCCCCEEEEEC
DKTKWELGEDEYFVLGDNRLPRESNDSRIFGPINKKDIVGRAFLRYFPFNKFGVL
CCCEEECCCCCEEEECCCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCHHHCCC
>Mature Secondary Structure 
TEKAKSFFEWLFVIGIAIVLALLLRNFVISTTHVEGNSMNPTIEQGDRIFVNRMGIFKN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHCCCEEEEEHHHHHHH
KLKRGNIIELHAPDKSGRDYIKRIVALPGDTVELKNNKVYVNNEQLNENYTSSQTTLVSG
HHCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEEECCEEEEECCCCCCCCCCCCEEEEEC
DKTKWELGEDEYFVLGDNRLPRESNDSRIFGPINKKDIVGRAFLRYFPFNKFGVL
CCCEEECCCCCEEEECCCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA