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The map label for this gene is coaE [H]

Identifier: 169824041

GI number: 169824041

Start: 400519

End: 401142

Strand: Direct

Name: coaE [H]

Synonym: FMG_0344

Alternate gene names: 169824041

Gene position: 400519-401142 (Clockwise)

Preceding gene: 169824040

Following gene: 169824042

Centisome position: 22.28

GC content: 29.81

Gene sequence:

>624_bases
GTGCAGATAATTGGTATGATGCAAAATAAAAAAATCATCGTAGTTTGTGGAAATATCGCAAGCGGGAAAAGTACGGTGTG
CAGAAGAATTAGAGAAAAAGGCTTTGTTGTAATAGATTTGGATGAGATTACTCACCAAATCTATGAGCAAGGTACAGATC
TTTATTACAAGCTTATTGATGAGTTTGGAAAAGAAATTTTAGACGAAAATTCTGACATAGATAGAAAAAAACTTTCCAAA
CTTGTATTTAATTCAAAAACATTATTAAAAAAGCTTGAAGAATTGACACATACTGATATAATATTAAGAGTAGTAAAAAG
AATTAAGAAGGAAAAGTCTGATTTGATTTTTCTAGAAATTTCTATGTATTTGGAAAGCAAAAATTTGGTTGACAAATATA
TCAACGTCGATGAAGATTGGGTAGTTGTAGCTGATAGGGACATTAGAATTCAAAGAATAATCGATAGAAACAACTTTGAT
TACGATACTGCGGTTACAAGAATTAATTCTCAGCTAGATTATGAGAAAAAAATTAGCGAATTTGACGAAGTTATTGTAAA
CAACACGACTGAATCAGATTTAATACTCAAAGTTGACGAACTAATAGATAGGGAAAAATTATGA

Upstream 100 bases:

>100_bases
GATTGTCCAAAAGACGAACGAGAAAAAGTTCTTGAAATAATGAAAGATGTCATGACACATGCTGTTGATTTGAAAGTCGA
TATGAAGATTGATGTAAACA

Downstream 100 bases:

>100_bases
AATTTATTAAAAGATTTTTAATCACGATTATTTCAATTATTGTGATTGTGTTTTTAGTTGGATTTGGCGTGAGTGCTTAT
TCTACTATGACAAGACCAGT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MQIIGMMQNKKIIVVCGNIASGKSTVCRRIREKGFVVIDLDEITHQIYEQGTDLYYKLIDEFGKEILDENSDIDRKKLSK
LVFNSKTLLKKLEELTHTDIILRVVKRIKKEKSDLIFLEISMYLESKNLVDKYINVDEDWVVVADRDIRIQRIIDRNNFD
YDTAVTRINSQLDYEKKISEFDEVIVNNTTESDLILKVDELIDREKL

Sequences:

>Translated_207_residues
MQIIGMMQNKKIIVVCGNIASGKSTVCRRIREKGFVVIDLDEITHQIYEQGTDLYYKLIDEFGKEILDENSDIDRKKLSK
LVFNSKTLLKKLEELTHTDIILRVVKRIKKEKSDLIFLEISMYLESKNLVDKYINVDEDWVVVADRDIRIQRIIDRNNFD
YDTAVTRINSQLDYEKKISEFDEVIVNNTTESDLILKVDELIDREKL
>Mature_207_residues
MQIIGMMQNKKIIVVCGNIASGKSTVCRRIREKGFVVIDLDEITHQIYEQGTDLYYKLIDEFGKEILDENSDIDRKKLSK
LVFNSKTLLKKLEELTHTDIILRVVKRIKKEKSDLIFLEISMYLESKNLVDKYINVDEDWVVVADRDIRIQRIIDRNNFD
YDTAVTRINSQLDYEKKISEFDEVIVNNTTESDLILKVDELIDREKL

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=183, Percent_Identity=31.6939890710383, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI191252795, Length=183, Percent_Identity=31.6939890710383, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI110227607, Length=193, Percent_Identity=27.4611398963731, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI205277394, Length=193, Percent_Identity=27.4611398963731, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI110227605, Length=193, Percent_Identity=27.4611398963731, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI110227603, Length=193, Percent_Identity=27.4611398963731, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI110227601, Length=193, Percent_Identity=27.4611398963731, Blast_Score=82, Evalue=3e-16,
Organism=Escherichia coli, GI1786292, Length=182, Percent_Identity=23.6263736263736, Blast_Score=61, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17554944, Length=196, Percent_Identity=31.1224489795918, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI25143409, Length=168, Percent_Identity=29.7619047619048, Blast_Score=81, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6320402, Length=201, Percent_Identity=27.8606965174129, Blast_Score=80, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24644728, Length=182, Percent_Identity=31.3186813186813, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24658602, Length=167, Percent_Identity=31.7365269461078, Blast_Score=89, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 24337; Mature: 24337

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIIGMMQNKKIIVVCGNIASGKSTVCRRIREKGFVVIDLDEITHQIYEQGTDLYYKLID
CCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCEEEEEHHHHHHHHHHCCHHHHHHHHH
EFGKEILDENSDIDRKKLSKLVFNSKTLLKKLEELTHTDIILRVVKRIKKEKSDLIFLEI
HHHHHHHCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
SMYLESKNLVDKYINVDEDWVVVADRDIRIQRIIDRNNFDYDTAVTRINSQLDYEKKISE
EEHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHH
FDEVIVNNTTESDLILKVDELIDREKL
HHHHHHCCCCCCHHEEEHHHHHCCCCC
>Mature Secondary Structure
MQIIGMMQNKKIIVVCGNIASGKSTVCRRIREKGFVVIDLDEITHQIYEQGTDLYYKLID
CCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCEEEEEHHHHHHHHHHCCHHHHHHHHH
EFGKEILDENSDIDRKKLSKLVFNSKTLLKKLEELTHTDIILRVVKRIKKEKSDLIFLEI
HHHHHHHCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
SMYLESKNLVDKYINVDEDWVVVADRDIRIQRIIDRNNFDYDTAVTRINSQLDYEKKISE
EEHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHH
FDEVIVNNTTESDLILKVDELIDREKL
HHHHHHCCCCCCHHEEEHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA