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The map label for this gene is mtbA [H]

Identifier: 169824009

GI number: 169824009

Start: 359996

End: 361111

Strand: Direct

Name: mtbA [H]

Synonym: FMG_0312

Alternate gene names: 169824009

Gene position: 359996-361111 (Clockwise)

Preceding gene: 169824008

Following gene: 169824010

Centisome position: 20.03

GC content: 32.08

Gene sequence:

>1116_bases
ATGAAAAAAAAGTATTTTTCGTTTGTAGATGAAGGATTAATCAAGATGACTTACACAGAAAGATTGAAGTCATATTTAGA
TGGTAATGTCGTGGATGTTGTTCCATTTGATCTTTTCGATGTAGAAACACCTTTGGCAACAAATATGGGATACACAAAAA
TAGATTTGATAAATGATTTTTCGTTGTATACTGATATGGTTCATCTCAAAAAATCTTTATATGGAATAGATTACATGTAT
ATTGGTATGGATCAAAAAGGAATTGGAAGCATTCTAGGTAGCGAAACTAGAATGACAGAAAATGGTGATTTTTTGACATC
TCATTATGCTATTGATGAATATGAATCAATGGCTAATTTGGGAAATATAGATGTAAGTAACAGTGAAACTGTGTGCAATT
TTATTGAAAAAGCAAAAAAGACGAAATCATCAATGGATGGAATCACAATATTCGGCGCAGTTACAGGTCCATTTACTACA
GCTTCTGGAGTCAGACCTGTTGAAAAACTTCTTCGCGATACGAGAAAAAATAAGGAAAATTTGCACGAATTATTAGATTT
GTGTACAAATTATACCATTGATTTTGTGAGAACTTTTACCGACGAAATAGGTGGATGTTTCTTCAAAATTGCTGATCCTG
TTGCATCGATGACAGTAATTAGTAAGAAACAATTTGAAGAATTTGCACAGCCTCATTTGACAAAATTGACAGATGCAATT
TATGAAATTACTGGAATCAAACCAATGGTTCATATTTGCGGTAAAACTGACAAAGTTTGGGAAAATTTCAAAGATACTAA
TTTCTCAAGATTTTCACTTGATAACATAGAAGATATGGGAGAATTCAAAAACATTCTTGGAAATTCTATGATAATCGAAG
GAAATATTGCGCCTATGGATATACTTTTGAATTCAGACCCACAAACTGTTAGAAACGAAGTAAAAAATATTTTGCAAAAA
GCTTCAGACAGTCCAAAAGGTTTCATATTAAATTCAGGATGTACCGTATGTGACCACACTCCAATAGAAAACATCGAAAG
CTACATTAAAGCAGTATGCGATTTTGGAAAAGATGCTTCGATTGGAAAATTACCAAAAGGATTATCCGACATATAA

Upstream 100 bases:

>100_bases
AATATTACAAAAAATAGATCCAAAAGCAAAACAATGTGGAGTTTGCAAAAAAACAGAAACTTCTGTAAAGATTAATTTAA
AATAATTTAGTGAGGATTTT

Downstream 100 bases:

>100_bases
ATTTATTAAATCAACAACCATTTATTTTTCGAAATTAAATGGTTGTTTTTGAATTAAAAAATGTATCCAAATATCGTAAT
ATCAAGACTTGAATATACTT

Product: putative metyhltransferase

Products: NA

Alternate protein names: MT2-A; Methylcobamide:CoM methyltransferase II isozyme A [H]

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MKKKYFSFVDEGLIKMTYTERLKSYLDGNVVDVVPFDLFDVETPLATNMGYTKIDLINDFSLYTDMVHLKKSLYGIDYMY
IGMDQKGIGSILGSETRMTENGDFLTSHYAIDEYESMANLGNIDVSNSETVCNFIEKAKKTKSSMDGITIFGAVTGPFTT
ASGVRPVEKLLRDTRKNKENLHELLDLCTNYTIDFVRTFTDEIGGCFFKIADPVASMTVISKKQFEEFAQPHLTKLTDAI
YEITGIKPMVHICGKTDKVWENFKDTNFSRFSLDNIEDMGEFKNILGNSMIIEGNIAPMDILLNSDPQTVRNEVKNILQK
ASDSPKGFILNSGCTVCDHTPIENIESYIKAVCDFGKDASIGKLPKGLSDI

Sequences:

>Translated_371_residues
MKKKYFSFVDEGLIKMTYTERLKSYLDGNVVDVVPFDLFDVETPLATNMGYTKIDLINDFSLYTDMVHLKKSLYGIDYMY
IGMDQKGIGSILGSETRMTENGDFLTSHYAIDEYESMANLGNIDVSNSETVCNFIEKAKKTKSSMDGITIFGAVTGPFTT
ASGVRPVEKLLRDTRKNKENLHELLDLCTNYTIDFVRTFTDEIGGCFFKIADPVASMTVISKKQFEEFAQPHLTKLTDAI
YEITGIKPMVHICGKTDKVWENFKDTNFSRFSLDNIEDMGEFKNILGNSMIIEGNIAPMDILLNSDPQTVRNEVKNILQK
ASDSPKGFILNSGCTVCDHTPIENIESYIKAVCDFGKDASIGKLPKGLSDI
>Mature_371_residues
MKKKYFSFVDEGLIKMTYTERLKSYLDGNVVDVVPFDLFDVETPLATNMGYTKIDLINDFSLYTDMVHLKKSLYGIDYMY
IGMDQKGIGSILGSETRMTENGDFLTSHYAIDEYESMANLGNIDVSNSETVCNFIEKAKKTKSSMDGITIFGAVTGPFTT
ASGVRPVEKLLRDTRKNKENLHELLDLCTNYTIDFVRTFTDEIGGCFFKIADPVASMTVISKKQFEEFAQPHLTKLTDAI
YEITGIKPMVHICGKTDKVWENFKDTNFSRFSLDNIEDMGEFKNILGNSMIIEGNIAPMDILLNSDPQTVRNEVKNILQK
ASDSPKGFILNSGCTVCDHTPIENIESYIKAVCDFGKDASIGKLPKGLSDI

Specific function: Catalyzes the transfer of the methyl group from the methylated corrinoid cofactor of mtmC, mtbC and mttC to coenzyme M [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uroporphyrinogen decarboxylase family. MtbA/mtaA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006360
- InterPro:   IPR000257 [H]

Pfam domain/function: PF01208 URO-D [H]

EC number: NA

Molecular weight: Translated: 41575; Mature: 41575

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKYFSFVDEGLIKMTYTERLKSYLDGNVVDVVPFDLFDVETPLATNMGYTKIDLINDF
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHCCCCCCCCCCCCEEEEEEHHH
SLYTDMVHLKKSLYGIDYMYIGMDQKGIGSILGSETRMTENGDFLTSHYAIDEYESMANL
HHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHC
GNIDVSNSETVCNFIEKAKKTKSSMDGITIFGAVTGPFTTASGVRPVEKLLRDTRKNKEN
CCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCHHH
LHELLDLCTNYTIDFVRTFTDEIGGCFFKIADPVASMTVISKKQFEEFAQPHLTKLTDAI
HHHHHHHHHCCHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
YEITGIKPMVHICGKTDKVWENFKDTNFSRFSLDNIEDMGEFKNILGNSMIIEGNIAPMD
HHHHCCCHHHHHCCCCHHHHHHHCCCCCCEEECCCHHHHHHHHHHHCCCEEEECCCCCEE
ILLNSDPQTVRNEVKNILQKASDSPKGFILNSGCTVCDHTPIENIESYIKAVCDFGKDAS
EEECCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCC
IGKLPKGLSDI
CCCCCCCCCCC
>Mature Secondary Structure
MKKKYFSFVDEGLIKMTYTERLKSYLDGNVVDVVPFDLFDVETPLATNMGYTKIDLINDF
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHCCCCCCCCCCCCEEEEEEHHH
SLYTDMVHLKKSLYGIDYMYIGMDQKGIGSILGSETRMTENGDFLTSHYAIDEYESMANL
HHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHC
GNIDVSNSETVCNFIEKAKKTKSSMDGITIFGAVTGPFTTASGVRPVEKLLRDTRKNKEN
CCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCHHH
LHELLDLCTNYTIDFVRTFTDEIGGCFFKIADPVASMTVISKKQFEEFAQPHLTKLTDAI
HHHHHHHHHCCHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
YEITGIKPMVHICGKTDKVWENFKDTNFSRFSLDNIEDMGEFKNILGNSMIIEGNIAPMD
HHHHCCCHHHHHCCCCHHHHHHHCCCCCCEEECCCHHHHHHHHHHHCCCEEEECCCCCEE
ILLNSDPQTVRNEVKNILQKASDSPKGFILNSGCTVCDHTPIENIESYIKAVCDFGKDAS
EEECCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCC
IGKLPKGLSDI
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]