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The map label for this gene is ykpA [H]

Identifier: 169824010

GI number: 169824010

Start: 361247

End: 362842

Strand: Direct

Name: ykpA [H]

Synonym: FMG_0313

Alternate gene names: 169824010

Gene position: 361247-362842 (Clockwise)

Preceding gene: 169824009

Following gene: 169824011

Centisome position: 20.1

GC content: 34.84

Gene sequence:

>1596_bases
ATGTTAACAGTTAACAATTTAAGTGTCATATTCCCCGATAAAAAATTATTTGAGGATGTTAACCTAATTTTTAATCCAGG
TAACTGTTACGGAGTTATTGGTGCGAATGGTGCTGGTAAATCAACGTTCCTCAAAATTTTATCCGGAGAAAAAGAGCCTA
CAAAAGGCAATGTCACGATAGATAAGAACACAAGATTATCAAAACTAAACCAAGATCACTACGCTTTTGAAGAAAACAGC
GTAATGGAAACAGTTTTGATGGGAAATAAGAAACTTTACGATATCCAAAAAGAAAAAGATGAGATATACATGAAGCCTGA
TTTCAGCGATGAAGACGGAATGAGAGCAGCGGAATTGGAAGCGGAATTCCAAGAACTTGGAGGATATGAAGCAGAAGCGG
AAAGTTCATCTTTGTTACAAGGTTTGGGAATTACAACAGAACAACATTATATGCTTATGAAAGATTTGAAAGAATCTGAC
AAGGTAAAAGTTTTGTTAGCGCAAGCTTTGTTCGGTAATCCAGGAATATTGCTACTAGACGAACCTACAAATGGTTTGGA
TTTGAAGGCAATATTGTGGCTTGAAGGCTTTCTAATGGATTTTCCAGGAATTGTAATCATAGTATCTCACGATAGATATT
TCTTGAATGAAGTGTGCACTCACATGGTGGATGTGGACTACGGAAAGATTAATATGTTTGTTGGTAACTACGATTTCTGG
TACGAATCAAGTCAACTTGCACTTAGAATGCAAAAAGAACAAAACAAGAAAAAAGAAGACAAAATTAAAGAATTACAAGA
ATTTATCCAAAGATTCTCCGCCAACAAATCAAAATCCAAGCAAGCTACAAGTAGAAAAAAACTTCTCGATAAAATCACGT
TGGATGACATTAAACCATCTAGTAGACGTTATCCATTTGTTGGATTTGAACTTTCGAGAGAAGTTGGCAACGAAATTCTA
AATGTAGACAACTTGACTGTAGAACAAAATGGCAGCAAACTAATCGACAATTTGACTTTCAGGGTCAACAAAGGAGATAA
GATTGGATTTATCGGAAACGAAATCGCCATCACGAAATTTTTCGAAATAATCAACGGAAACGATGATAATTATTCTGGAG
AATACAAGTGGGGACAAACTATTACTAATACGTATTTTCCAAAGGATAATACAAAATATTTCGAAGATTGCGATTTGAAT
TTGATTGATTGGTTGAGACAATTCAGCGAAGAAAAATCAGAAATTCACATCAGAGGATTCTTGGGCAAGATGCTATTTTC
AGGAGACGAAGCATTGAAGAAATCCAACGTTCTAAGCGGTGGTGAAAAAGTTAGAATGATGTTTTCAAAAATGATGGTAA
CACCTGCGAATGTTTTGGTGTTCGACCAACCTACAAACCATTTGGATTTGGAAAGTATCGAGGCCGTAAACAATGGGCTA
ATCGCATTCAAATCAAACATTTTGTTCACATCACTAGATCACCAATTTGTATCTTCTGTGGCAAATAGAATTATTGAAAT
ATTTGATGACGGAACTTATCGTGACGTATCAATGAATTACGAAGACTATATAGAAAAATATTTAACTAATAATTAG

Upstream 100 bases:

>100_bases
TAAATGGTTGTTTTTGAATTAAAAAATGTATCCAAATATCGTAATATCAAGACTTGAATATACTTTTATGGTATAATATG
TGAGTATTGGAGGGATTTAG

Downstream 100 bases:

>100_bases
GAGTAGAAATGAAACATCAATTAGTTATTGTAGTAGATTTTGGAGGACAATATAATCAACTAATCGCTCGTCGTGTCAGA
GATTTGAACGTGTACTGCGA

Product: macrolide ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 531; Mature: 531

Protein sequence:

>531_residues
MLTVNNLSVIFPDKKLFEDVNLIFNPGNCYGVIGANGAGKSTFLKILSGEKEPTKGNVTIDKNTRLSKLNQDHYAFEENS
VMETVLMGNKKLYDIQKEKDEIYMKPDFSDEDGMRAAELEAEFQELGGYEAEAESSSLLQGLGITTEQHYMLMKDLKESD
KVKVLLAQALFGNPGILLLDEPTNGLDLKAILWLEGFLMDFPGIVIIVSHDRYFLNEVCTHMVDVDYGKINMFVGNYDFW
YESSQLALRMQKEQNKKKEDKIKELQEFIQRFSANKSKSKQATSRKKLLDKITLDDIKPSSRRYPFVGFELSREVGNEIL
NVDNLTVEQNGSKLIDNLTFRVNKGDKIGFIGNEIAITKFFEIINGNDDNYSGEYKWGQTITNTYFPKDNTKYFEDCDLN
LIDWLRQFSEEKSEIHIRGFLGKMLFSGDEALKKSNVLSGGEKVRMMFSKMMVTPANVLVFDQPTNHLDLESIEAVNNGL
IAFKSNILFTSLDHQFVSSVANRIIEIFDDGTYRDVSMNYEDYIEKYLTNN

Sequences:

>Translated_531_residues
MLTVNNLSVIFPDKKLFEDVNLIFNPGNCYGVIGANGAGKSTFLKILSGEKEPTKGNVTIDKNTRLSKLNQDHYAFEENS
VMETVLMGNKKLYDIQKEKDEIYMKPDFSDEDGMRAAELEAEFQELGGYEAEAESSSLLQGLGITTEQHYMLMKDLKESD
KVKVLLAQALFGNPGILLLDEPTNGLDLKAILWLEGFLMDFPGIVIIVSHDRYFLNEVCTHMVDVDYGKINMFVGNYDFW
YESSQLALRMQKEQNKKKEDKIKELQEFIQRFSANKSKSKQATSRKKLLDKITLDDIKPSSRRYPFVGFELSREVGNEIL
NVDNLTVEQNGSKLIDNLTFRVNKGDKIGFIGNEIAITKFFEIINGNDDNYSGEYKWGQTITNTYFPKDNTKYFEDCDLN
LIDWLRQFSEEKSEIHIRGFLGKMLFSGDEALKKSNVLSGGEKVRMMFSKMMVTPANVLVFDQPTNHLDLESIEAVNNGL
IAFKSNILFTSLDHQFVSSVANRIIEIFDDGTYRDVSMNYEDYIEKYLTNN
>Mature_531_residues
MLTVNNLSVIFPDKKLFEDVNLIFNPGNCYGVIGANGAGKSTFLKILSGEKEPTKGNVTIDKNTRLSKLNQDHYAFEENS
VMETVLMGNKKLYDIQKEKDEIYMKPDFSDEDGMRAAELEAEFQELGGYEAEAESSSLLQGLGITTEQHYMLMKDLKESD
KVKVLLAQALFGNPGILLLDEPTNGLDLKAILWLEGFLMDFPGIVIIVSHDRYFLNEVCTHMVDVDYGKINMFVGNYDFW
YESSQLALRMQKEQNKKKEDKIKELQEFIQRFSANKSKSKQATSRKKLLDKITLDDIKPSSRRYPFVGFELSREVGNEIL
NVDNLTVEQNGSKLIDNLTFRVNKGDKIGFIGNEIAITKFFEIINGNDDNYSGEYKWGQTITNTYFPKDNTKYFEDCDLN
LIDWLRQFSEEKSEIHIRGFLGKMLFSGDEALKKSNVLSGGEKVRMMFSKMMVTPANVLVFDQPTNHLDLESIEAVNNGL
IAFKSNILFTSLDHQFVSSVANRIIEIFDDGTYRDVSMNYEDYIEKYLTNN

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=536, Percent_Identity=28.544776119403, Blast_Score=222, Evalue=8e-58,
Organism=Homo sapiens, GI10947137, Length=531, Percent_Identity=26.9303201506591, Blast_Score=193, Evalue=4e-49,
Organism=Homo sapiens, GI27881506, Length=531, Percent_Identity=26.9303201506591, Blast_Score=192, Evalue=5e-49,
Organism=Homo sapiens, GI69354671, Length=559, Percent_Identity=25.0447227191413, Blast_Score=156, Evalue=5e-38,
Organism=Homo sapiens, GI10947135, Length=559, Percent_Identity=25.0447227191413, Blast_Score=156, Evalue=6e-38,
Organism=Homo sapiens, GI105990541, Length=232, Percent_Identity=26.2931034482759, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI1787041, Length=526, Percent_Identity=45.8174904942966, Blast_Score=476, Evalue=1e-135,
Organism=Escherichia coli, GI1789751, Length=518, Percent_Identity=28.1853281853282, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI2367384, Length=529, Percent_Identity=29.1115311909263, Blast_Score=219, Evalue=4e-58,
Organism=Escherichia coli, GI1787182, Length=543, Percent_Identity=27.4401473296501, Blast_Score=199, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI17553372, Length=505, Percent_Identity=29.5049504950495, Blast_Score=211, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17555318, Length=523, Percent_Identity=23.3269598470363, Blast_Score=176, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI17559834, Length=542, Percent_Identity=23.9852398523985, Blast_Score=159, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6320874, Length=523, Percent_Identity=28.4894837476099, Blast_Score=196, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6321121, Length=534, Percent_Identity=26.2172284644195, Blast_Score=181, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6325030, Length=238, Percent_Identity=28.1512605042017, Blast_Score=85, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6323278, Length=258, Percent_Identity=25.968992248062, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324314, Length=371, Percent_Identity=22.911051212938, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24666836, Length=530, Percent_Identity=25.8490566037736, Blast_Score=204, Evalue=2e-52,
Organism=Drosophila melanogaster, GI24642252, Length=538, Percent_Identity=25.2788104089219, Blast_Score=195, Evalue=5e-50,
Organism=Drosophila melanogaster, GI18859989, Length=538, Percent_Identity=25.2788104089219, Blast_Score=195, Evalue=5e-50,
Organism=Drosophila melanogaster, GI24641342, Length=544, Percent_Identity=25, Blast_Score=174, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 60667; Mature: 60667

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTVNNLSVIFPDKKLFEDVNLIFNPGNCYGVIGANGAGKSTFLKILSGEKEPTKGNVTI
CEEECCEEEEECCHHHHCCCCEEECCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCEEE
DKNTRLSKLNQDHYAFEENSVMETVLMGNKKLYDIQKEKDEIYMKPDFSDEDGMRAAELE
CCCCCHHHCCCCCCCCCCCHHHHHHHHCCCEEEECCCCCCCEEECCCCCCCCCCCHHHHH
AEFQELGGYEAEAESSSLLQGLGITTEQHYMLMKDLKESDKVKVLLAQALFGNPGILLLD
HHHHHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHHCCCCCHHEEEEEHHHCCCCCEEEEE
EPTNGLDLKAILWLEGFLMDFPGIVIIVSHDRYFLNEVCTHMVDVDYGKINMFVGNYDFW
CCCCCCCEEHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCEEEE
YESSQLALRMQKEQNKKKEDKIKELQEFIQRFSANKSKSKQATSRKKLLDKITLDDIKPS
ECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCC
SRRYPFVGFELSREVGNEILNVDNLTVEQNGSKLIDNLTFRVNKGDKIGFIGNEIAITKF
CCCCCEEEEEHHHHHHHHHCCCCCEEEECCCCEEECCEEEEECCCCEEEECCCHHHHHHH
FEIINGNDDNYSGEYKWGQTITNTYFPKDNTKYFEDCDLNLIDWLRQFSEEKSEIHIRGF
HHHHCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEHHH
LGKMLFSGDEALKKSNVLSGGEKVRMMFSKMMVTPANVLVFDQPTNHLDLESIEAVNNGL
HHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHCCCE
IAFKSNILFTSLDHQFVSSVANRIIEIFDDGTYRDVSMNYEDYIEKYLTNN
EEEECCEEEEECCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHCCC
>Mature Secondary Structure
MLTVNNLSVIFPDKKLFEDVNLIFNPGNCYGVIGANGAGKSTFLKILSGEKEPTKGNVTI
CEEECCEEEEECCHHHHCCCCEEECCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCEEE
DKNTRLSKLNQDHYAFEENSVMETVLMGNKKLYDIQKEKDEIYMKPDFSDEDGMRAAELE
CCCCCHHHCCCCCCCCCCCHHHHHHHHCCCEEEECCCCCCCEEECCCCCCCCCCCHHHHH
AEFQELGGYEAEAESSSLLQGLGITTEQHYMLMKDLKESDKVKVLLAQALFGNPGILLLD
HHHHHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHHCCCCCHHEEEEEHHHCCCCCEEEEE
EPTNGLDLKAILWLEGFLMDFPGIVIIVSHDRYFLNEVCTHMVDVDYGKINMFVGNYDFW
CCCCCCCEEHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCEEEE
YESSQLALRMQKEQNKKKEDKIKELQEFIQRFSANKSKSKQATSRKKLLDKITLDDIKPS
ECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCC
SRRYPFVGFELSREVGNEILNVDNLTVEQNGSKLIDNLTFRVNKGDKIGFIGNEIAITKF
CCCCCEEEEEHHHHHHHHHCCCCCEEEECCCCEEECCEEEEECCCCEEEECCCHHHHHHH
FEIINGNDDNYSGEYKWGQTITNTYFPKDNTKYFEDCDLNLIDWLRQFSEEKSEIHIRGF
HHHHCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEHHH
LGKMLFSGDEALKKSNVLSGGEKVRMMFSKMMVTPANVLVFDQPTNHLDLESIEAVNNGL
HHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHCCCE
IAFKSNILFTSLDHQFVSSVANRIIEIFDDGTYRDVSMNYEDYIEKYLTNN
EEEECCEEEEECCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]