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The map label for this gene is htpG

Identifier: 167623527

GI number: 167623527

Start: 1913688

End: 1915607

Strand: Direct

Name: htpG

Synonym: Shal_1596

Alternate gene names: 167623527

Gene position: 1913688-1915607 (Clockwise)

Preceding gene: 167623526

Following gene: 167623528

Centisome position: 36.61

GC content: 46.04

Gene sequence:

>1920_bases
ATGTCACAACAAGAGACGCACGGCTTTCAAACTGAAGTCAAACAGCTACTACATTTAATGATCCACTCTTTGTACTCAAA
CAAAGAGATCTTTTTGCGTGAGTTAGTATCTAACGCAGCCGATGCAGCCGATAAGCTACGCTATGAAGCCCTAACGAATG
ATGCTCTTTATGAGGGTGACGGTGAGTTACGTGTTCGCATTAGTGCCGATAAAGAGAAAGGTACCGTAACAATTGAAGAC
AACGGTATCGGTATGACTCGCGATGGTGTGATTGAGCACCTAGGTACAATCGCAAAGTCTGGTACTGCTGAATTTTTTAA
GAACATGTCTGGTGACGAGTCAAAAGACTCACAGTTAATTGGTCAGTTCGGTGTCGGTTTCTACTCTTCATTTATTGTTG
CAGACCGAGTGACAGTGCGTACCCGCGCTGCCGGCCATAGCGCTGATGAAGCGGTACTGTGGGAGTCTGCCGGTGAAGGT
GACTTCACGGTTGAAACCATCACTAAGCAGAGCCGTGGTACTGAAATTACTCTACATCTTCGCGATGACGAAAAAGAGTT
TGCAGACGACTATCGTCTACGCTCAATTATTACTAAGTACTCAGATCATATCTCTGTTCCAGTAGAGATGTATGAAGAAG
GCACGCCTGCGGTTGAAGCGACAGAAGAGGGCGGTGAAGCGATTCCTGCTACTGAAGGTCACTGGAAGCTAATGAACAAG
GCGACAGCACTTTGGACTCGCAACAAGAGTGATGTGTCTGACGAAGAGTATCAAGAATTTTATAAGTATATCTCTCATGA
CTTTACCGACCCACTATTGTGGAGCCACAACCGCGTGGAAGGTAAGCAAGAGTACACCAGCTTACTGTATATCCCAGCGA
AAGCGCCTTGGGATATGTGGAACCGCGACCGTAAGCACGGTCTAAAGTTATTCGTTCAGCGTGTATTCGTTATGGATGAT
GCAGAGCAGTTTATGCCGAGTTACCTGCGTTTTGTACAAGGTTTGATTGACTCGAACGATCTGCCACTAAACGTATCACG
TGAAATCTTGCAAGATAACAAGGTAACCACAGCGCTTCGTACCGCAGTGACTAAGCGTGTACTTGGCATGCTAGAAAAGC
TTGCTAAGAATGACGCTGAAAAGTATCAGTCTTTCTGGACCGAGTTTGGCCAAGTACTAAAAGAAGGTCCCGCTGAGGAT
TTTGCTAATAAAGAGCGTGTAGCGGGTCTGCTGCGTTTCGCATCGACTCACACAGGCGAAGCAACAGCCAATGTATCGTT
GGCTGATTATGTTGAACGCATGAAAGAAGGTCAGTCTAAGATCTATTTCATTGTCGCTGATAGCTATGAAGCTGCCGCAA
ATAGCCCGCATCTTGAATTGCTACGTAAGAAGGGCATTGAAGTCTTATTAATGTCAGAGCGTATCGATGAGTGGTTGATT
AATCACTTAACTGAATTTGACGGTAAAAAGTTACACTCAGTGACACGTGGCGACCTTGAGCTAGGTGAGCTAGAAGATGC
TAGCGAAAAAGAGGCGCAAGAGAAGCTAGAAACTGAATCTGAAGGCCTAGTTAAGCGCGTTAAAGACAGCCTAGGCGATA
AAGTGTCAGCGGTTAAAGTGACGACACGTCTAACCGATACCCCTGCATGTGTGGTTGCTGGTGAGGGCGAGATGTCAACC
CAGATGATTAAGTTGATGCAAGCTGCTGGACAAGACGTGCCTGAATCTAAGCCTACATTTGAGCTAAACCCTGAGCATCC
GCTAGTTGCGCGTTTAAATGACGAGCAGGACGAGCAGCGATTTGCTCAGTGGTCAGAGCTACTATTGCAGCAGGCATTGT
TGTCAGAAAAAGGCAGCCTTGCAGATCCATCGGCATTTATTAAGCTAATGAACCAAATGCTATTAGCTAGCGTTAAGTAA

Upstream 100 bases:

>100_bases
GCAATTGAAGACAATGCCAGATTTATCCCTTGAAAAGTCATTTTATAGCCCCATCTTATTTGTAAGCTTTATTTAAACTG
ATTTTTAAAGGGAACATTTC

Downstream 100 bases:

>100_bases
TTAGCAGCTATGATTAAAGGGGCAGTTACACTGCCTCTTTTTTATGGTCCAGATAAGTTCAGGCGAAAGCGAAAGGAAAG
TTATGGAATCGATTCTAGAA

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 639; Mature: 638

Protein sequence:

>639_residues
MSQQETHGFQTEVKQLLHLMIHSLYSNKEIFLRELVSNAADAADKLRYEALTNDALYEGDGELRVRISADKEKGTVTIED
NGIGMTRDGVIEHLGTIAKSGTAEFFKNMSGDESKDSQLIGQFGVGFYSSFIVADRVTVRTRAAGHSADEAVLWESAGEG
DFTVETITKQSRGTEITLHLRDDEKEFADDYRLRSIITKYSDHISVPVEMYEEGTPAVEATEEGGEAIPATEGHWKLMNK
ATALWTRNKSDVSDEEYQEFYKYISHDFTDPLLWSHNRVEGKQEYTSLLYIPAKAPWDMWNRDRKHGLKLFVQRVFVMDD
AEQFMPSYLRFVQGLIDSNDLPLNVSREILQDNKVTTALRTAVTKRVLGMLEKLAKNDAEKYQSFWTEFGQVLKEGPAED
FANKERVAGLLRFASTHTGEATANVSLADYVERMKEGQSKIYFIVADSYEAAANSPHLELLRKKGIEVLLMSERIDEWLI
NHLTEFDGKKLHSVTRGDLELGELEDASEKEAQEKLETESEGLVKRVKDSLGDKVSAVKVTTRLTDTPACVVAGEGEMST
QMIKLMQAAGQDVPESKPTFELNPEHPLVARLNDEQDEQRFAQWSELLLQQALLSEKGSLADPSAFIKLMNQMLLASVK

Sequences:

>Translated_639_residues
MSQQETHGFQTEVKQLLHLMIHSLYSNKEIFLRELVSNAADAADKLRYEALTNDALYEGDGELRVRISADKEKGTVTIED
NGIGMTRDGVIEHLGTIAKSGTAEFFKNMSGDESKDSQLIGQFGVGFYSSFIVADRVTVRTRAAGHSADEAVLWESAGEG
DFTVETITKQSRGTEITLHLRDDEKEFADDYRLRSIITKYSDHISVPVEMYEEGTPAVEATEEGGEAIPATEGHWKLMNK
ATALWTRNKSDVSDEEYQEFYKYISHDFTDPLLWSHNRVEGKQEYTSLLYIPAKAPWDMWNRDRKHGLKLFVQRVFVMDD
AEQFMPSYLRFVQGLIDSNDLPLNVSREILQDNKVTTALRTAVTKRVLGMLEKLAKNDAEKYQSFWTEFGQVLKEGPAED
FANKERVAGLLRFASTHTGEATANVSLADYVERMKEGQSKIYFIVADSYEAAANSPHLELLRKKGIEVLLMSERIDEWLI
NHLTEFDGKKLHSVTRGDLELGELEDASEKEAQEKLETESEGLVKRVKDSLGDKVSAVKVTTRLTDTPACVVAGEGEMST
QMIKLMQAAGQDVPESKPTFELNPEHPLVARLNDEQDEQRFAQWSELLLQQALLSEKGSLADPSAFIKLMNQMLLASVK
>Mature_638_residues
SQQETHGFQTEVKQLLHLMIHSLYSNKEIFLRELVSNAADAADKLRYEALTNDALYEGDGELRVRISADKEKGTVTIEDN
GIGMTRDGVIEHLGTIAKSGTAEFFKNMSGDESKDSQLIGQFGVGFYSSFIVADRVTVRTRAAGHSADEAVLWESAGEGD
FTVETITKQSRGTEITLHLRDDEKEFADDYRLRSIITKYSDHISVPVEMYEEGTPAVEATEEGGEAIPATEGHWKLMNKA
TALWTRNKSDVSDEEYQEFYKYISHDFTDPLLWSHNRVEGKQEYTSLLYIPAKAPWDMWNRDRKHGLKLFVQRVFVMDDA
EQFMPSYLRFVQGLIDSNDLPLNVSREILQDNKVTTALRTAVTKRVLGMLEKLAKNDAEKYQSFWTEFGQVLKEGPAEDF
ANKERVAGLLRFASTHTGEATANVSLADYVERMKEGQSKIYFIVADSYEAAANSPHLELLRKKGIEVLLMSERIDEWLIN
HLTEFDGKKLHSVTRGDLELGELEDASEKEAQEKLETESEGLVKRVKDSLGDKVSAVKVTTRLTDTPACVVAGEGEMSTQ
MIKLMQAAGQDVPESKPTFELNPEHPLVARLNDEQDEQRFAQWSELLLQQALLSEKGSLADPSAFIKLMNQMLLASVK

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI4507677, Length=686, Percent_Identity=38.0466472303207, Blast_Score=437, Evalue=1e-122,
Organism=Homo sapiens, GI20149594, Length=678, Percent_Identity=36.5781710914454, Blast_Score=388, Evalue=1e-108,
Organism=Homo sapiens, GI155722983, Length=648, Percent_Identity=34.8765432098765, Blast_Score=376, Evalue=1e-104,
Organism=Homo sapiens, GI154146191, Length=408, Percent_Identity=38.4803921568627, Blast_Score=278, Evalue=1e-74,
Organism=Homo sapiens, GI153792590, Length=408, Percent_Identity=38.4803921568627, Blast_Score=275, Evalue=9e-74,
Organism=Escherichia coli, GI1786679, Length=636, Percent_Identity=67.9245283018868, Blast_Score=892, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=668, Percent_Identity=37.4251497005988, Blast_Score=446, Evalue=1e-125,
Organism=Caenorhabditis elegans, GI17542208, Length=679, Percent_Identity=37.5552282768778, Blast_Score=409, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI115535205, Length=655, Percent_Identity=32.9770992366412, Blast_Score=323, Evalue=2e-88,
Organism=Caenorhabditis elegans, GI115535167, Length=444, Percent_Identity=35.8108108108108, Blast_Score=267, Evalue=2e-71,
Organism=Saccharomyces cerevisiae, GI6323840, Length=684, Percent_Identity=37.8654970760234, Blast_Score=454, Evalue=1e-128,
Organism=Saccharomyces cerevisiae, GI6325016, Length=680, Percent_Identity=37.7941176470588, Blast_Score=442, Evalue=1e-125,
Organism=Drosophila melanogaster, GI17647529, Length=684, Percent_Identity=37.5730994152047, Blast_Score=467, Evalue=1e-132,
Organism=Drosophila melanogaster, GI21357739, Length=678, Percent_Identity=38.7905604719764, Blast_Score=424, Evalue=1e-118,
Organism=Drosophila melanogaster, GI24586016, Length=648, Percent_Identity=34.4135802469136, Blast_Score=369, Evalue=1e-102,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_SHEHH (B0TP05)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001673821.1
- ProteinModelPortal:   B0TP05
- SMR:   B0TP05
- GeneID:   5906428
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_1596
- HOGENOM:   HBG631012
- OMA:   KYIANAY
- ProtClustDB:   PRK05218
- BioCyc:   SHAL458817:SHAL_1596-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 71936; Mature: 71804

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQQETHGFQTEVKQLLHLMIHSLYSNKEIFLRELVSNAADAADKLRYEALTNDALYEGD
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECC
GELRVRISADKEKGTVTIEDNGIGMTRDGVIEHLGTIAKSGTAEFFKNMSGDESKDSQLI
CCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHH
GQFGVGFYSSFIVADRVTVRTRAAGHSADEAVLWESAGEGDFTVETITKQSRGTEITLHL
HHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEECCCCCCCEEHHHHHHCCCCCEEEEEE
RDDEKEFADDYRLRSIITKYSDHISVPVEMYEEGTPAVEATEEGGEAIPATEGHWKLMNK
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCEEECCCCCCCCCCCCCHHHHHHH
ATALWTRNKSDVSDEEYQEFYKYISHDFTDPLLWSHNRVEGKQEYTSLLYIPAKAPWDMW
HHHHEECCCCCCCHHHHHHHHHHHHHCCCCCHHCCCCCCCCHHHHCEEEEEECCCCHHHH
NRDRKHGLKLFVQRVFVMDDAEQFMPSYLRFVQGLIDSNDLPLNVSREILQDNKVTTALR
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHH
TAVTKRVLGMLEKLAKNDAEKYQSFWTEFGQVLKEGPAEDFANKERVAGLLRFASTHTGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHCCCCC
ATANVSLADYVERMKEGQSKIYFIVADSYEAAANSPHLELLRKKGIEVLLMSERIDEWLI
CCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCEEEEHHHHHHHHHH
NHLTEFDGKKLHSVTRGDLELGELEDASEKEAQEKLETESEGLVKRVKDSLGDKVSAVKV
HHHHHCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
TTRLTDTPACVVAGEGEMSTQMIKLMQAAGQDVPESKPTFELNPEHPLVARLNDEQDEQR
EEEECCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCEEECCCCCEEEECCCCHHHHH
FAQWSELLLQQALLSEKGSLADPSAFIKLMNQMLLASVK
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQQETHGFQTEVKQLLHLMIHSLYSNKEIFLRELVSNAADAADKLRYEALTNDALYEGD
CCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECC
GELRVRISADKEKGTVTIEDNGIGMTRDGVIEHLGTIAKSGTAEFFKNMSGDESKDSQLI
CCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHH
GQFGVGFYSSFIVADRVTVRTRAAGHSADEAVLWESAGEGDFTVETITKQSRGTEITLHL
HHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEECCCCCCCEEHHHHHHCCCCCEEEEEE
RDDEKEFADDYRLRSIITKYSDHISVPVEMYEEGTPAVEATEEGGEAIPATEGHWKLMNK
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCEEECCCCCCCCCCCCCHHHHHHH
ATALWTRNKSDVSDEEYQEFYKYISHDFTDPLLWSHNRVEGKQEYTSLLYIPAKAPWDMW
HHHHEECCCCCCCHHHHHHHHHHHHHCCCCCHHCCCCCCCCHHHHCEEEEEECCCCHHHH
NRDRKHGLKLFVQRVFVMDDAEQFMPSYLRFVQGLIDSNDLPLNVSREILQDNKVTTALR
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHH
TAVTKRVLGMLEKLAKNDAEKYQSFWTEFGQVLKEGPAEDFANKERVAGLLRFASTHTGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHCCCCC
ATANVSLADYVERMKEGQSKIYFIVADSYEAAANSPHLELLRKKGIEVLLMSERIDEWLI
CCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCEEEEHHHHHHHHHH
NHLTEFDGKKLHSVTRGDLELGELEDASEKEAQEKLETESEGLVKRVKDSLGDKVSAVKV
HHHHHCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
TTRLTDTPACVVAGEGEMSTQMIKLMQAAGQDVPESKPTFELNPEHPLVARLNDEQDEQR
EEEECCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCEEECCCCCEEEECCCCHHHHH
FAQWSELLLQQALLSEKGSLADPSAFIKLMNQMLLASVK
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA