Click here to switch to the map view.

The map label for this gene is murG

Identifier: 167622395

GI number: 167622395

Start: 534249

End: 535346

Strand: Direct

Name: murG

Synonym: Shal_0455

Alternate gene names: 167622395

Gene position: 534249-535346 (Clockwise)

Preceding gene: 167622394

Following gene: 167622396

Centisome position: 10.22

GC content: 47.54

Gene sequence:

>1098_bases
ATGACTAACCAAGCTGAAGAAAAACGCATTTTAATCATGGCTGGCGGTACTGGCGGTCATGTATTTCCTGCGCTAGCGGT
TGCTAAATATTTGAGTCAGCAAGGCTGGAAAGTGCGTTGGTTAGGTACCGCCGAGCGAATGGAGGCGAGGTTAGTCCCTC
AACATGGCTTCGATATCGATTTTATTGATATTAAAGGTGTGCGCGGAAATGGCTTGATGCGAAAGCTCGCAGCACCGTTT
AAGATTATCCGCTCGGTGATGCAAGCTCGTGCAGTGATTAAAAAGTTTAAACCCCATGTGGTGATGGGGATGGGCGGCTT
TGCTAGCGGTCCGGGTGGCGTCGCTGCAAAACTGAGTGGTATCCCTTTGGTTCTGCATGAACAGAATGCGATTCCGGGAA
TGACCAATAGGTTGTTATCGCGTATTGCCTCAGAGGTATTATGCGCGTTTGACGGTACATTTACCGACATTAAAGCTGAA
ACCGTCGGTAACCCTATTCGTAAAGAGCTTATTGCCCTAGGCGAAAAGCGAAAGCCTGTTTGTGACGATGATTCGCTCAA
GGTACTTGTTGTCGGCGGTAGCTTGGGAGCAAAGATTTTTAATGATGTCATGCCAAGTGTATTAGAAGGGGTGAGCAAAA
CCCATTCAATGACGGTTTGGCATCAAGTTGGGCGTGACAACTTAGCGACCGTTAAAGCTGAATATCAGCGATTAGGTCAA
GATGGCAGTGTAAGCGTCGCCGAGTTTATTGATGATATGGAAGCGGCTTATCGCTGGGCGGATGTAGTGGTGTGCCGCTC
AGGAGCGTTAACCGTATCGGAGTTGGCCGCAGTCGGTTTACCGAGTCTGCTAGTGCCATATCCACATGCCGTAGATGATC
ATCAGACTAAAAATGCCAAAGTATTAGTCAACGCTGGGGCAGCATTTTTACTGCCACAGCCAATAGTCGATACCAGCAAG
TTAATGACTAAATTGTCGATGCTGGCATCTGATAAACAAGAATTATGCAATATGGGCCAGCGTGCTCGAGACGTAGCAAT
CTTAGATGCAACTCAAAGAGTTGCCAACGTCTGCATTCGTTTAGCTGAAAAGGGTTGA

Upstream 100 bases:

>100_bases
TGACGGCGGCAGCCATGCTGCTTATCCGGATTGATCATGAAAGACGATTAAGCGTTATTCAGGCCGTTGAAGGCCGGACA
AGTAAACAATGAGTGAATTA

Downstream 100 bases:

>100_bases
GATGAGTAACAAAGCAGAGAAGTATTCGCAGCTAAGATCCATGATCCCTGAAATGCGCAGGGTTAAGCACATCTATTTCG
TTGGAATAGGTGGTGCGGGC

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MTNQAEEKRILIMAGGTGGHVFPALAVAKYLSQQGWKVRWLGTAERMEARLVPQHGFDIDFIDIKGVRGNGLMRKLAAPF
KIIRSVMQARAVIKKFKPHVVMGMGGFASGPGGVAAKLSGIPLVLHEQNAIPGMTNRLLSRIASEVLCAFDGTFTDIKAE
TVGNPIRKELIALGEKRKPVCDDDSLKVLVVGGSLGAKIFNDVMPSVLEGVSKTHSMTVWHQVGRDNLATVKAEYQRLGQ
DGSVSVAEFIDDMEAAYRWADVVVCRSGALTVSELAAVGLPSLLVPYPHAVDDHQTKNAKVLVNAGAAFLLPQPIVDTSK
LMTKLSMLASDKQELCNMGQRARDVAILDATQRVANVCIRLAEKG

Sequences:

>Translated_365_residues
MTNQAEEKRILIMAGGTGGHVFPALAVAKYLSQQGWKVRWLGTAERMEARLVPQHGFDIDFIDIKGVRGNGLMRKLAAPF
KIIRSVMQARAVIKKFKPHVVMGMGGFASGPGGVAAKLSGIPLVLHEQNAIPGMTNRLLSRIASEVLCAFDGTFTDIKAE
TVGNPIRKELIALGEKRKPVCDDDSLKVLVVGGSLGAKIFNDVMPSVLEGVSKTHSMTVWHQVGRDNLATVKAEYQRLGQ
DGSVSVAEFIDDMEAAYRWADVVVCRSGALTVSELAAVGLPSLLVPYPHAVDDHQTKNAKVLVNAGAAFLLPQPIVDTSK
LMTKLSMLASDKQELCNMGQRARDVAILDATQRVANVCIRLAEKG
>Mature_364_residues
TNQAEEKRILIMAGGTGGHVFPALAVAKYLSQQGWKVRWLGTAERMEARLVPQHGFDIDFIDIKGVRGNGLMRKLAAPFK
IIRSVMQARAVIKKFKPHVVMGMGGFASGPGGVAAKLSGIPLVLHEQNAIPGMTNRLLSRIASEVLCAFDGTFTDIKAET
VGNPIRKELIALGEKRKPVCDDDSLKVLVVGGSLGAKIFNDVMPSVLEGVSKTHSMTVWHQVGRDNLATVKAEYQRLGQD
GSVSVAEFIDDMEAAYRWADVVVCRSGALTVSELAAVGLPSLLVPYPHAVDDHQTKNAKVLVNAGAAFLLPQPIVDTSKL
MTKLSMLASDKQELCNMGQRARDVAILDATQRVANVCIRLAEKG

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=356, Percent_Identity=52.247191011236, Blast_Score=355, Evalue=2e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_SHEHH (B0TQN7)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001672689.1
- ProteinModelPortal:   B0TQN7
- SMR:   B0TQN7
- GeneID:   5906795
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_0455
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- ProtClustDB:   PRK00726
- BioCyc:   SHAL458817:SHAL_0455-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 39332; Mature: 39201

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNQAEEKRILIMAGGTGGHVFPALAVAKYLSQQGWKVRWLGTAERMEARLVPQHGFDID
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHCCCCCCCCEE
FIDIKGVRGNGLMRKLAAPFKIIRSVMQARAVIKKFKPHVVMGMGGFASGPGGVAAKLSG
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEECC
IPLVLHEQNAIPGMTNRLLSRIASEVLCAFDGTFTDIKAETVGNPIRKELIALGEKRKPV
CEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEHHHCCCHHHHHHHHHCCCCCCC
CDDDSLKVLVVGGSLGAKIFNDVMPSVLEGVSKTHSMTVWHQVGRDNLATVKAEYQRLGQ
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
DGSVSVAEFIDDMEAAYRWADVVVCRSGALTVSELAAVGLPSLLVPYPHAVDDHQTKNAK
CCCEEHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHCCCHHHCCCCCCCCCCCCCCCE
VLVNAGAAFLLPQPIVDTSKLMTKLSMLASDKQELCNMGQRARDVAILDATQRVANVCIR
EEEECCCCEECCCCCCCHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LAEKG
HHCCC
>Mature Secondary Structure 
TNQAEEKRILIMAGGTGGHVFPALAVAKYLSQQGWKVRWLGTAERMEARLVPQHGFDID
CCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHCCCCCCCCEE
FIDIKGVRGNGLMRKLAAPFKIIRSVMQARAVIKKFKPHVVMGMGGFASGPGGVAAKLSG
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEECC
IPLVLHEQNAIPGMTNRLLSRIASEVLCAFDGTFTDIKAETVGNPIRKELIALGEKRKPV
CEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEHHHCCCHHHHHHHHHCCCCCCC
CDDDSLKVLVVGGSLGAKIFNDVMPSVLEGVSKTHSMTVWHQVGRDNLATVKAEYQRLGQ
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
DGSVSVAEFIDDMEAAYRWADVVVCRSGALTVSELAAVGLPSLLVPYPHAVDDHQTKNAK
CCCEEHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHCCCHHHCCCCCCCCCCCCCCCE
VLVNAGAAFLLPQPIVDTSKLMTKLSMLASDKQELCNMGQRARDVAILDATQRVANVCIR
EEEECCCCEECCCCCCCHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LAEKG
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA