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The map label for this gene is ftsW [H]

Identifier: 167622394

GI number: 167622394

Start: 533020

End: 534240

Strand: Direct

Name: ftsW [H]

Synonym: Shal_0454

Alternate gene names: 167622394

Gene position: 533020-534240 (Clockwise)

Preceding gene: 167622393

Following gene: 167622395

Centisome position: 10.2

GC content: 47.01

Gene sequence:

>1221_bases
ATGGCGAGTAGTGAGAAGCAGTTAAGCCTATTTAGCAACCGCTTTAAGTGGTCGTTGCCGAATTTGTTTAATGATAACTC
TGCTCCAGGGATGCAGCTGTACGATAGAGCATTGTTATTTGCTGTTTTGTCGTTGATCTGTTTTGGCTTTGTGATGGTGA
TGTCAGCCTCTATGCCTGAGGCACAAACGTTAACGGGTAACCCGTTTCATTTTGTGTGGCGTCATGGTGCTTATTTAATC
GGTTGCGTAATTATTGCCGCGGTAGTGTTGCAAATAGAGATGCGTCATTGGCAACACTTTAGCCCATGGTTGCTGGTTGT
GGTTGGCATCATGCTGGTAGCGGTACTGTTTGTGGGCACAACCGTTAACGGGGCAACGCGTTGGTTATCGATTGGGCCTA
TCCGTATTCAGGTAGCCGAGGTTGCTAAGTTTGCCTTTGCCATATACATGGCAGGCTACTTGGTACGTCGTCACCAAGAG
ATTAGAGAAAACGCCAAAGGCTTCTATAAGCCTATTGCTGTTTTTGCCGTGTATGCTTTTCTGATTTTGATGCAACCTGA
TTTAGGCACCGTGGTCGTACTGTTTGTGGGTACCGTCGGTTTACTGTTTTTAGCGGGCGCGAGATTACTGGATTTCTTCG
CGCTGATCTTAACCGGGATATTGGCATTTGTGGCCTTAGTATTACTTGAGCCCTACCGAATGCGACGTGTGACTTCGTTC
CTCGATCCTTGGCAAGATCCGTTTGGTAGCGGTTATCAGCTGACTCAGTCACTGATGGCTTATGGACGCGGTGATTGGTT
TGGCCAGGGCTTAGGCAACAGTATTCAGAAGTTAGAGTATCTGCCGGAGGCACATACCGACTTTATCTTTGCCGTGATTG
GTGAAGAGTTAGGATTTATCGGCATTATCGCCGTATTAGCTGTGTTGCTATTTGTCGCACTTAGAGCGATTAAGCTAGGC
AGTATGTGTTTAGCACTTGAGCGAGCATTTGAAGGTTATCTTGCCTATGGCATCGGGATCTGGATCTGCTTCCAAACCGT
GGTCAACGTTGGCGCCAGTATTGGTATGTTGCCAACCAAAGGATTAACTCTGCCATTTATTAGCTATGGCGGTAGTAGTT
TATGGGTCATGACGGCGGCAGCCATGCTGCTTATCCGGATTGATCATGAAAGACGATTAAGCGTTATTCAGGCCGTTGAA
GGCCGGACAAGTAAACAATGA

Upstream 100 bases:

>100_bases
GGTGATATTGTTATTTTATCACCCGCTTGCTCTAGCTTAGATATGTATCCTAATTTTATGGCGCGTGGCGATGAATTTCG
CAGCTTGGTAGAAGCGCTTC

Downstream 100 bases:

>100_bases
GTGAATTAATGACTAACCAAGCTGAAGAAAAACGCATTTTAATCATGGCTGGCGGTACTGGCGGTCATGTATTTCCTGCG
CTAGCGGTTGCTAAATATTT

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MASSEKQLSLFSNRFKWSLPNLFNDNSAPGMQLYDRALLFAVLSLICFGFVMVMSASMPEAQTLTGNPFHFVWRHGAYLI
GCVIIAAVVLQIEMRHWQHFSPWLLVVVGIMLVAVLFVGTTVNGATRWLSIGPIRIQVAEVAKFAFAIYMAGYLVRRHQE
IRENAKGFYKPIAVFAVYAFLILMQPDLGTVVVLFVGTVGLLFLAGARLLDFFALILTGILAFVALVLLEPYRMRRVTSF
LDPWQDPFGSGYQLTQSLMAYGRGDWFGQGLGNSIQKLEYLPEAHTDFIFAVIGEELGFIGIIAVLAVLLFVALRAIKLG
SMCLALERAFEGYLAYGIGIWICFQTVVNVGASIGMLPTKGLTLPFISYGGSSLWVMTAAAMLLIRIDHERRLSVIQAVE
GRTSKQ

Sequences:

>Translated_406_residues
MASSEKQLSLFSNRFKWSLPNLFNDNSAPGMQLYDRALLFAVLSLICFGFVMVMSASMPEAQTLTGNPFHFVWRHGAYLI
GCVIIAAVVLQIEMRHWQHFSPWLLVVVGIMLVAVLFVGTTVNGATRWLSIGPIRIQVAEVAKFAFAIYMAGYLVRRHQE
IRENAKGFYKPIAVFAVYAFLILMQPDLGTVVVLFVGTVGLLFLAGARLLDFFALILTGILAFVALVLLEPYRMRRVTSF
LDPWQDPFGSGYQLTQSLMAYGRGDWFGQGLGNSIQKLEYLPEAHTDFIFAVIGEELGFIGIIAVLAVLLFVALRAIKLG
SMCLALERAFEGYLAYGIGIWICFQTVVNVGASIGMLPTKGLTLPFISYGGSSLWVMTAAAMLLIRIDHERRLSVIQAVE
GRTSKQ
>Mature_405_residues
ASSEKQLSLFSNRFKWSLPNLFNDNSAPGMQLYDRALLFAVLSLICFGFVMVMSASMPEAQTLTGNPFHFVWRHGAYLIG
CVIIAAVVLQIEMRHWQHFSPWLLVVVGIMLVAVLFVGTTVNGATRWLSIGPIRIQVAEVAKFAFAIYMAGYLVRRHQEI
RENAKGFYKPIAVFAVYAFLILMQPDLGTVVVLFVGTVGLLFLAGARLLDFFALILTGILAFVALVLLEPYRMRRVTSFL
DPWQDPFGSGYQLTQSLMAYGRGDWFGQGLGNSIQKLEYLPEAHTDFIFAVIGEELGFIGIIAVLAVLLFVALRAIKLGS
MCLALERAFEGYLAYGIGIWICFQTVVNVGASIGMLPTKGLTLPFISYGGSSLWVMTAAAMLLIRIDHERRLSVIQAVEG
RTSKQ

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=375, Percent_Identity=56.5333333333333, Blast_Score=421, Evalue=1e-119,
Organism=Escherichia coli, GI1786853, Length=316, Percent_Identity=33.8607594936709, Blast_Score=151, Evalue=8e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 44975; Mature: 44844

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ASSEKQLSLFSNRFKWSLPNLFNDNSAPGMQLYDRALLFAVLSLICFGFVMVMSASMPE
CCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC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CCCCCHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]