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The map label for this gene is dapA [H]

Identifier: 167040547

GI number: 167040547

Start: 1929727

End: 1930626

Strand: Reverse

Name: dapA [H]

Synonym: Teth514_1917

Alternate gene names: 167040547

Gene position: 1930626-1929727 (Counterclockwise)

Preceding gene: 167040548

Following gene: 167040546

Centisome position: 78.57

GC content: 33.0

Gene sequence:

>900_bases
ATGAGTATAAGAGAAAAACTTACAGGAGTATTTGCGCCACTTGTAACTCCTTTTGTTAATCAAGAAATTGATTATGAAAA
GTTGAAAGAGAATATTCAGAAATTAAATAGTTCTAAATTAAAAGGTTATTTATGCTTAGGAAGCAATGGCGAATTTAGAA
GTTTAACAGATGAAGAGGCAATTAAAGTTATAAAAACAGCTGCAAAGAGTAAATCAAAAGATAAAACTTTGCTTGCTGGT
ACAGGAAGAGAATCAGCATGGGCTACAATAGAATTTACTAAAAAAGTAGCAGATTTTGGAGTTGATTTTGCCAGTGTTCT
TACACCTCATTATTTTGCTAGTAAAATGACTGATGAAGCATTAATCAAATTTTATACTGAAGTTGCTGATAAATCTCCTA
TTCCGATAACAATTTATTGCATTCCCAGATCTGCAAATGGAGTATTAATTTCTCCTCGAGCAATTTCTGTACTTGCGCAA
CATCCTAATATAGTTGGCATAAAAGATTCTTCAAAAGAAGATATAGGAAATTATGTAAATGCTGTACCTAAGGGAGCAGA
GTTCTATGTACTTTCCGGCTCTATAAATAAATTTTTGGACGGTCTAAAAAAAGGAGCTATAGGCGGTGTTCTTTCAATGG
CAAATTACCTGCCTGACCTTTGCTGTGAAATTCAAGAATTATTTAATGAGGGCAAGTATCAAGAAGCAGAAGAACTAAGT
AACAGACTTTGTAAAATTAATGAAAAAATATCCGGCAAAGGTGGAGTAACAGCTGTTAAAGTAGCAATGAATTGGTTAGG
TTATTATGGAATGGAGCCAAGACTACCATTATTACCGTTAAATGAAAATGAAATTGAGGAAATTAGAAGAATTTTACAGG
AAGAAGGGCTACTTGCATGA

Upstream 100 bases:

>100_bases
TTACTGCTTAAAATAGAGGTTGAAATAGAAAACAAAACGAAAATAATGACTGTAAATTATTAAATGTAGTTTTAAACTAA
AAAAGGAGGATATTACTGTA

Downstream 100 bases:

>100_bases
AAAAAGTATTGCTTTCAGAGGAGATACATCCAGAGGGAAGAAAGTTATTAGAGGGAAAATTTGAAATTGTTACAGCACCT
GATACAAGTCAACAAACGCT

Product: dihydrodipicolinate synthetase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MSIREKLTGVFAPLVTPFVNQEIDYEKLKENIQKLNSSKLKGYLCLGSNGEFRSLTDEEAIKVIKTAAKSKSKDKTLLAG
TGRESAWATIEFTKKVADFGVDFASVLTPHYFASKMTDEALIKFYTEVADKSPIPITIYCIPRSANGVLISPRAISVLAQ
HPNIVGIKDSSKEDIGNYVNAVPKGAEFYVLSGSINKFLDGLKKGAIGGVLSMANYLPDLCCEIQELFNEGKYQEAEELS
NRLCKINEKISGKGGVTAVKVAMNWLGYYGMEPRLPLLPLNENEIEEIRRILQEEGLLA

Sequences:

>Translated_299_residues
MSIREKLTGVFAPLVTPFVNQEIDYEKLKENIQKLNSSKLKGYLCLGSNGEFRSLTDEEAIKVIKTAAKSKSKDKTLLAG
TGRESAWATIEFTKKVADFGVDFASVLTPHYFASKMTDEALIKFYTEVADKSPIPITIYCIPRSANGVLISPRAISVLAQ
HPNIVGIKDSSKEDIGNYVNAVPKGAEFYVLSGSINKFLDGLKKGAIGGVLSMANYLPDLCCEIQELFNEGKYQEAEELS
NRLCKINEKISGKGGVTAVKVAMNWLGYYGMEPRLPLLPLNENEIEEIRRILQEEGLLA
>Mature_298_residues
SIREKLTGVFAPLVTPFVNQEIDYEKLKENIQKLNSSKLKGYLCLGSNGEFRSLTDEEAIKVIKTAAKSKSKDKTLLAGT
GRESAWATIEFTKKVADFGVDFASVLTPHYFASKMTDEALIKFYTEVADKSPIPITIYCIPRSANGVLISPRAISVLAQH
PNIVGIKDSSKEDIGNYVNAVPKGAEFYVLSGSINKFLDGLKKGAIGGVLSMANYLPDLCCEIQELFNEGKYQEAEELSN
RLCKINEKISGKGGVTAVKVAMNWLGYYGMEPRLPLLPLNENEIEEIRRILQEEGLLA

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=295, Percent_Identity=38.9830508474576, Blast_Score=217, Evalue=1e-56,
Organism=Homo sapiens, GI197927274, Length=95, Percent_Identity=34.7368421052632, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1788823, Length=298, Percent_Identity=26.510067114094, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1786463, Length=248, Percent_Identity=27.8225806451613, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87082415, Length=304, Percent_Identity=23.3552631578947, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1789620, Length=300, Percent_Identity=25.3333333333333, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR002220
- InterPro:   IPR020625 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 32952; Mature: 32821

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIREKLTGVFAPLVTPFVNQEIDYEKLKENIQKLNSSKLKGYLCLGSNGEFRSLTDEEA
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHH
IKVIKTAAKSKSKDKTLLAGTGRESAWATIEFTKKVADFGVDFASVLTPHYFASKMTDEA
HHHHHHHHHCCCCCCEEEEECCCCCCEEEHHHHHHHHHHCCCHHHHHCHHHHHHHHHHHH
LIKFYTEVADKSPIPITIYCIPRSANGVLISPRAISVLAQHPNIVGIKDSSKEDIGNYVN
HHHHHHHHHCCCCCCEEEEEEECCCCCEEECCHHHHHHHCCCCEEEECCCCHHHHHHHHH
AVPKGAEFYVLSGSINKFLDGLKKGAIGGVLSMANYLPDLCCEIQELFNEGKYQEAEELS
HCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
NRLCKINEKISGKGGVTAVKVAMNWLGYYGMEPRLPLLPLNENEIEEIRRILQEEGLLA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCEECCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SIREKLTGVFAPLVTPFVNQEIDYEKLKENIQKLNSSKLKGYLCLGSNGEFRSLTDEEA
CHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHH
IKVIKTAAKSKSKDKTLLAGTGRESAWATIEFTKKVADFGVDFASVLTPHYFASKMTDEA
HHHHHHHHHCCCCCCEEEEECCCCCCEEEHHHHHHHHHHCCCHHHHHCHHHHHHHHHHHH
LIKFYTEVADKSPIPITIYCIPRSANGVLISPRAISVLAQHPNIVGIKDSSKEDIGNYVN
HHHHHHHHHCCCCCCEEEEEEECCCCCEEECCHHHHHHHCCCCEEEECCCCHHHHHHHHH
AVPKGAEFYVLSGSINKFLDGLKKGAIGGVLSMANYLPDLCCEIQELFNEGKYQEAEELS
HCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
NRLCKINEKISGKGGVTAVKVAMNWLGYYGMEPRLPLLPLNENEIEEIRRILQEEGLLA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCEECCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA