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The map label for this gene is fba [H]

Identifier: 167040548

GI number: 167040548

Start: 1930899

End: 1931825

Strand: Reverse

Name: fba [H]

Synonym: Teth514_1918

Alternate gene names: 167040548

Gene position: 1931825-1930899 (Counterclockwise)

Preceding gene: 167040549

Following gene: 167040547

Centisome position: 78.62

GC content: 34.84

Gene sequence:

>927_bases
ATGCCACTTGTAACAAGTAAGGAAATGCTTATTTATGCAAGAGAGAATGGATTTGCAGTAGGAGCTTTCAATGCTTATAA
CATGGAAGTGGTTCAAGCTATAATCGAGGCAGCTGAAGAGGAAAATGCTCCTGTGATAATTCAGATAAGTGAAGGAGCAA
TAGCATATGGGGGTGAGAAATCATTTGCGGCTCTAATTAAAGTATTAGCTGAGGAAGCTACAGTACCTGTAGTATGCCAT
TTGGACCATGGAGTAAACTTTTCTACAGTTATAAAAGCATTAAAAGCAGGATTTACATCACTTATGTTTGATGGGTCGTC
TCTTACGTTTGAAGAGAATATAAAAAAAACAAAAAAATTAGTTGAAATAGCACATGCTGCAGGAATTCCTTTAGAAGGGG
AAATTGGGAAAATACCTGATGCAGCTAAGGGGCCCCTTTCTCCAGAGGAAGTAAAAAAATATCTTACGACTCCAGAAGAA
GCTCTAGAATTTTATGAAAAGACAGGAGTAGATTCACTGGCAATTTCAGTGGGAAGCGCTCACAGAATGAAAGTTCAATC
TGTGCAATTAGATATTGAAAGAATAGCACGAATAAAAGACAAGGTAAAAATACCATTAGTACTTCATGGTGCTTCTGGAG
TAATGGATGACTCTGTTATTCAAGCAGTAAAAGCTGGGATTTCAAAAGTTAATTTTGCTACAGAATTAAATAAGGCTTTT
ACCAATGCTTTAAGGGAAAAATTATCAAATAACCCGGATTTAGTTGATGTTAGAAAATATGGTGCCGTAGCAAGAGAAAA
TGTAAAAAAGACTGTAAAAGAAAAAATACAACTATTGAATGCTACTAATAAAGCACCAGAGATATTAAAACTTATTAATA
AAAGAAGTTTTGCAATGGGAAATAAAGATGTGGAAGCTATAGAATAA

Upstream 100 bases:

>100_bases
AAAAAAGGAGTATCTAACCCAAGACATTTAGGTGAAGCAGGAGTTACATTACAGGAATTTAATTTCATAAAAGAATATCT
AATATAAAGGAGCTGATATA

Downstream 100 bases:

>100_bases
CAATAACTTTAGTTTGCAAATGAGGTAATGATAGACTGTCTGTGAGCATTGCATTTGTGCATTGAAATAAAAAATAAATG
GCAAATTTGCATTAACGATT

Product: ketose-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MPLVTSKEMLIYARENGFAVGAFNAYNMEVVQAIIEAAEEENAPVIIQISEGAIAYGGEKSFAALIKVLAEEATVPVVCH
LDHGVNFSTVIKALKAGFTSLMFDGSSLTFEENIKKTKKLVEIAHAAGIPLEGEIGKIPDAAKGPLSPEEVKKYLTTPEE
ALEFYEKTGVDSLAISVGSAHRMKVQSVQLDIERIARIKDKVKIPLVLHGASGVMDDSVIQAVKAGISKVNFATELNKAF
TNALREKLSNNPDLVDVRKYGAVARENVKKTVKEKIQLLNATNKAPEILKLINKRSFAMGNKDVEAIE

Sequences:

>Translated_308_residues
MPLVTSKEMLIYARENGFAVGAFNAYNMEVVQAIIEAAEEENAPVIIQISEGAIAYGGEKSFAALIKVLAEEATVPVVCH
LDHGVNFSTVIKALKAGFTSLMFDGSSLTFEENIKKTKKLVEIAHAAGIPLEGEIGKIPDAAKGPLSPEEVKKYLTTPEE
ALEFYEKTGVDSLAISVGSAHRMKVQSVQLDIERIARIKDKVKIPLVLHGASGVMDDSVIQAVKAGISKVNFATELNKAF
TNALREKLSNNPDLVDVRKYGAVARENVKKTVKEKIQLLNATNKAPEILKLINKRSFAMGNKDVEAIE
>Mature_307_residues
PLVTSKEMLIYARENGFAVGAFNAYNMEVVQAIIEAAEEENAPVIIQISEGAIAYGGEKSFAALIKVLAEEATVPVVCHL
DHGVNFSTVIKALKAGFTSLMFDGSSLTFEENIKKTKKLVEIAHAAGIPLEGEIGKIPDAAKGPLSPEEVKKYLTTPEEA
LEFYEKTGVDSLAISVGSAHRMKVQSVQLDIERIARIKDKVKIPLVLHGASGVMDDSVIQAVKAGISKVNFATELNKAFT
NALREKLSNNPDLVDVRKYGAVARENVKKTVKEKIQLLNATNKAPEILKLINKRSFAMGNKDVEAIE

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI87082041, Length=276, Percent_Identity=36.5942028985507, Blast_Score=203, Evalue=9e-54,
Organism=Escherichia coli, GI1789526, Length=284, Percent_Identity=35.9154929577465, Blast_Score=197, Evalue=6e-52,
Organism=Escherichia coli, GI1788072, Length=269, Percent_Identity=38.2899628252788, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1789293, Length=271, Percent_Identity=26.5682656826568, Blast_Score=65, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6322790, Length=291, Percent_Identity=26.8041237113402, Blast_Score=79, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011289
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 33390; Mature: 33259

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLVTSKEMLIYARENGFAVGAFNAYNMEVVQAIIEAAEEENAPVIIQISEGAIAYGGEK
CCCCCCCCEEEEECCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEECCCEEEECCCH
SFAALIKVLAEEATVPVVCHLDHGVNFSTVIKALKAGFTSLMFDGSSLTFEENIKKTKKL
HHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCHHHEEECCCCCCHHHHHHHHHHH
VEIAHAAGIPLEGEIGKIPDAAKGPLSPEEVKKYLTTPEEALEFYEKTGVDSLAISVGSA
HHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHCCCCCEEEECCCC
HRMKVQSVQLDIERIARIKDKVKIPLVLHGASGVMDDSVIQAVKAGISKVNFATELNKAF
HHEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TNALREKLSNNPDLVDVRKYGAVARENVKKTVKEKIQLLNATNKAPEILKLINKRSFAMG
HHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
NKDVEAIE
CCCHHHCC
>Mature Secondary Structure 
PLVTSKEMLIYARENGFAVGAFNAYNMEVVQAIIEAAEEENAPVIIQISEGAIAYGGEK
CCCCCCCEEEEECCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEECCCEEEECCCH
SFAALIKVLAEEATVPVVCHLDHGVNFSTVIKALKAGFTSLMFDGSSLTFEENIKKTKKL
HHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCHHHEEECCCCCCHHHHHHHHHHH
VEIAHAAGIPLEGEIGKIPDAAKGPLSPEEVKKYLTTPEEALEFYEKTGVDSLAISVGSA
HHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHCCCCCEEEECCCC
HRMKVQSVQLDIERIARIKDKVKIPLVLHGASGVMDDSVIQAVKAGISKVNFATELNKAF
HHEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TNALREKLSNNPDLVDVRKYGAVARENVKKTVKEKIQLLNATNKAPEILKLINKRSFAMG
HHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
NKDVEAIE
CCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA