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The map label for this gene is dinB [H]

Identifier: 167038865

GI number: 167038865

Start: 196112

End: 197281

Strand: Direct

Name: dinB [H]

Synonym: Teth514_0195

Alternate gene names: 167038865

Gene position: 196112-197281 (Clockwise)

Preceding gene: 167038864

Following gene: 167038866

Centisome position: 7.98

GC content: 34.62

Gene sequence:

>1170_bases
ATGAAACGAAAGATTATTCATGTTGATATGGATGCTTTTTTTGCATCTGTAGAACAACATGATAATCCGGAATACAAAGG
GAAACCTGTTATTGTAGGAGGTCTGTCGGGAAGAGGGGTAGTTTCAACTTGCTCCTATGAGGCAAGAAAGTACGGAATAC
ATTCTGCAATGCCGATGTACATGGCAAGGAAGCTATGTCCACACGGTATTTTTCTTTCTGTAAGGAGAAAAAGATATGAA
GAGGTTTCAGCTCAAATTTTTGATATCCTGTACAGTATAACTCCTTTAGTGGAACCTGTTTCTATAGATGAAGCCTATCT
TGATGTTACAGATATTGACAAAAATCCAGAGATTATTGCCCTGGAAATAAAAAAGAAAGTGAAGGAAACGACAGGACTTA
CTATTTCTGCAGGAGTTTCCTATAATAAATTTCTTGCAAAACTTGCCTCAGATTGGAATAAGCCAGACGGATTTATGGTC
ATAACAGAAGACATGATTCCCGACATTTTAAAACCACTTCCCGTTTCCAAAGTTTATGGTATAGGGCAAAAATCCGAAGA
AAGACTTAAATCTATGGGAATAAATACAATAGGTGACCTTTTAAAACTGTCACAGGAGAATCTTGTTGAAATTTTTGGTA
AAGTAGGTGTGGAGATATATTTAAGAATCCGTGGCATTGATGAGAGGCCTGTTGAAACTATGAGGGAGATTAAGTCTATA
GGAAAGGAAAAAACATTGGAAAAAGATACAAAAGATAAAAAACTTTTGCTTCGCTATGCGAAATTATTTTCCGACATAAT
ATCGGAAGAATTGTTTAGAGAGAGGCTTTATGCCAGAACAGTTACTGTTAAGATAAAAACATCAGATTTTACAGTTCACA
CCAAAAGCAAAACTTTAAATAAATATATACGATTAGGTGAGGACATATACGATGTAGCCTACGAAATTATTGAAAGTCTA
AAATTAGACCAATATATAAGGCTTATTGGTCTATCTGTTTCTAACTTGAGTGCAGTAAAATATGAGCAATTGTCCTTTTT
GGATAAAAGGGTTATTAAATTTATTAAAGCAGAAAATGTAGTTAGAGAAATAAATAAAAAGATGGGGCAGGAAGTAGTGA
AAAAGGCAAGTGAACTTTTAAAAGAGGAAACGAAGCAACGGAGGGATTAA

Upstream 100 bases:

>100_bases
AAGGTCTTTAAATTTGTCCAACTCTGTAGCTATAGTACTGTATGAGGCCTTGAGACAACTGGGTTTTCCTAATATGAAAT
AAAAAAATTGAGGGATGATT

Downstream 100 bases:

>100_bases
ATTGGAAGCAAAAGAGAGGCATAAGCGCAATGTTGCTAAAGAAATTATAGAATTGGCTTGGCCTTCTATAACAGAACAAA
TGCTTATAATGACAGTTGGA

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MKRKIIHVDMDAFFASVEQHDNPEYKGKPVIVGGLSGRGVVSTCSYEARKYGIHSAMPMYMARKLCPHGIFLSVRRKRYE
EVSAQIFDILYSITPLVEPVSIDEAYLDVTDIDKNPEIIALEIKKKVKETTGLTISAGVSYNKFLAKLASDWNKPDGFMV
ITEDMIPDILKPLPVSKVYGIGQKSEERLKSMGINTIGDLLKLSQENLVEIFGKVGVEIYLRIRGIDERPVETMREIKSI
GKEKTLEKDTKDKKLLLRYAKLFSDIISEELFRERLYARTVTVKIKTSDFTVHTKSKTLNKYIRLGEDIYDVAYEIIESL
KLDQYIRLIGLSVSNLSAVKYEQLSFLDKRVIKFIKAENVVREINKKMGQEVVKKASELLKEETKQRRD

Sequences:

>Translated_389_residues
MKRKIIHVDMDAFFASVEQHDNPEYKGKPVIVGGLSGRGVVSTCSYEARKYGIHSAMPMYMARKLCPHGIFLSVRRKRYE
EVSAQIFDILYSITPLVEPVSIDEAYLDVTDIDKNPEIIALEIKKKVKETTGLTISAGVSYNKFLAKLASDWNKPDGFMV
ITEDMIPDILKPLPVSKVYGIGQKSEERLKSMGINTIGDLLKLSQENLVEIFGKVGVEIYLRIRGIDERPVETMREIKSI
GKEKTLEKDTKDKKLLLRYAKLFSDIISEELFRERLYARTVTVKIKTSDFTVHTKSKTLNKYIRLGEDIYDVAYEIIESL
KLDQYIRLIGLSVSNLSAVKYEQLSFLDKRVIKFIKAENVVREINKKMGQEVVKKASELLKEETKQRRD
>Mature_389_residues
MKRKIIHVDMDAFFASVEQHDNPEYKGKPVIVGGLSGRGVVSTCSYEARKYGIHSAMPMYMARKLCPHGIFLSVRRKRYE
EVSAQIFDILYSITPLVEPVSIDEAYLDVTDIDKNPEIIALEIKKKVKETTGLTISAGVSYNKFLAKLASDWNKPDGFMV
ITEDMIPDILKPLPVSKVYGIGQKSEERLKSMGINTIGDLLKLSQENLVEIFGKVGVEIYLRIRGIDERPVETMREIKSI
GKEKTLEKDTKDKKLLLRYAKLFSDIISEELFRERLYARTVTVKIKTSDFTVHTKSKTLNKYIRLGEDIYDVAYEIIESL
KLDQYIRLIGLSVSNLSAVKYEQLSFLDKRVIKFIKAENVVREINKKMGQEVVKKASELLKEETKQRRD

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=296, Percent_Identity=30.7432432432432, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI7706681, Length=297, Percent_Identity=30.6397306397306, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI154350220, Length=405, Percent_Identity=25.1851851851852, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI5729982, Length=324, Percent_Identity=27.7777777777778, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI7705344, Length=110, Percent_Identity=42.7272727272727, Blast_Score=106, Evalue=3e-23,
Organism=Escherichia coli, GI1786425, Length=359, Percent_Identity=40.6685236768802, Blast_Score=231, Evalue=9e-62,
Organism=Escherichia coli, GI1787432, Length=408, Percent_Identity=24.5098039215686, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI193205700, Length=265, Percent_Identity=35.0943396226415, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI193205702, Length=265, Percent_Identity=35.0943396226415, Blast_Score=114, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17537959, Length=344, Percent_Identity=27.906976744186, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI115534089, Length=124, Percent_Identity=37.0967741935484, Blast_Score=79, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6324921, Length=295, Percent_Identity=25.7627118644068, Blast_Score=90, Evalue=5e-19,
Organism=Drosophila melanogaster, GI19923006, Length=440, Percent_Identity=24.7727272727273, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI21355641, Length=286, Percent_Identity=29.3706293706294, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24644984, Length=286, Percent_Identity=29.3706293706294, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24668444, Length=119, Percent_Identity=34.453781512605, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 44546; Mature: 44546

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRKIIHVDMDAFFASVEQHDNPEYKGKPVIVGGLSGRGVVSTCSYEARKYGIHSAMPMY
CCCEEEEEEHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCHHHCCHHHHHHCCHHHHHHH
MARKLCPHGIFLSVRRKRYEEVSAQIFDILYSITPLVEPVSIDEAYLDVTDIDKNPEIIA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEHCCCCCCCCEEE
LEIKKKVKETTGLTISAGVSYNKFLAKLASDWNKPDGFMVITEDMIPDILKPLPVSKVYG
EHHHHHHHHHCCCEEECCCCHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHCCCCCHHHHC
IGQKSEERLKSMGINTIGDLLKLSQENLVEIFGKVGVEIYLRIRGIDERPVETMREIKSI
CCCHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHHH
GKEKTLEKDTKDKKLLLRYAKLFSDIISEELFRERLYARTVTVKIKTSDFTVHTKSKTLN
CHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCEEEEEHHHHHH
KYIRLGEDIYDVAYEIIESLKLDQYIRLIGLSVSNLSAVKYEQLSFLDKRVIKFIKAENV
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VREINKKMGQEVVKKASELLKEETKQRRD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKRKIIHVDMDAFFASVEQHDNPEYKGKPVIVGGLSGRGVVSTCSYEARKYGIHSAMPMY
CCCEEEEEEHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCHHHCCHHHHHHCCHHHHHHH
MARKLCPHGIFLSVRRKRYEEVSAQIFDILYSITPLVEPVSIDEAYLDVTDIDKNPEIIA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEHCCCCCCCCEEE
LEIKKKVKETTGLTISAGVSYNKFLAKLASDWNKPDGFMVITEDMIPDILKPLPVSKVYG
EHHHHHHHHHCCCEEECCCCHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHCCCCCHHHHC
IGQKSEERLKSMGINTIGDLLKLSQENLVEIFGKVGVEIYLRIRGIDERPVETMREIKSI
CCCHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHHH
GKEKTLEKDTKDKKLLLRYAKLFSDIISEELFRERLYARTVTVKIKTSDFTVHTKSKTLN
CHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCEEEEEHHHHHH
KYIRLGEDIYDVAYEIIESLKLDQYIRLIGLSVSNLSAVKYEQLSFLDKRVIKFIKAENV
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VREINKKMGQEVVKKASELLKEETKQRRD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]