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The map label for this gene is yaeL [C]

Identifier: 161870880

GI number: 161870880

Start: 2019663

End: 2021087

Strand: Direct

Name: yaeL [C]

Synonym: NMCC_1969

Alternate gene names: 161870880

Gene position: 2019663-2021087 (Clockwise)

Preceding gene: 161870879

Following gene: 161870881

Centisome position: 93.79

GC content: 58.39

Gene sequence:

>1425_bases
ATGCCCGGACACGCGCACAAGCGCGGGCATTTATCGGCACACTGCGCTGATGCCGTCCGAACACCGTTATCAAAGGAAAA
CCATTTGCACACCCTTCTAGCTTTTATCTTCGCCATCCTGATTTTGGTCAGCCTGCACGAGTTCGGACACTACATCGTTG
CCAGATTGTGCGGCGTCAAAGTCGTACGCTTTTCCGTCGGCTTCGGCAAACCGTTTTTCACCCGAAAGCGCGGCGACACC
GAATGGTGCCTCGCCCCGATTCCGTTGGGCGGTTACGTCAAAATGGTCGATACGCGCGAAGGCGAAGTATCAGAAGCCGA
TTTACCCTACGCTTTTGACAAACAACACCCCGCCAAGCGCATCGCCATCGTCGCCGCCGGCCCACTGACCAACCTCGCAC
TGGCGGTTTTGCTGTACGGACTGAGCTTTTCCTTCGGCGTAACCGAACTGCGCCCCTACGTCGGCACAGTCGAACCCGAC
ACCATTGCCGCCCGCGCCGGCTTCCAAAGCGGCGACAAAATACAATCCGTCAACGGCACACCCGTTGCAGATTGGGGCAG
CGCGCAAACTGAAATCGTCCTCAACCTCGAAGCCGGCAAAGTCGCCGTCGGCGTTCAGACGGCATCGGGCGCGCAAACCG
TCCGCACCATCGATGCCGCAAGCACGCCGGAAGCCGGTAAAATCGCAAAAAACCAAGGCTACATCGGACTGATGCCCTTT
AAAATCACAACCGTTGCTGGCGGCGTGGAAAAAGGCAGCCCCGCCGAAAAAGCAGGCCTGAAACCGGGCGACAGGCTGAC
TGCCGCCGACGGCAAACCCATTACCTCATGGCAAGAATGGGCAAACCTGACCCGTCAAAGCCCGGGCAGGAAAATTGCCT
TAACCTACGAACGCGCCGGACAAACCCATACCGCCGACATCCGCCCCGATACTGTCGAACAGTCCGACCACACCCTGATC
GGGCGCGTCGGCCTCCGTCCGCAGCCGGACAGGGCGTGGGACGCGCAAATCCGCCGCAGCTACCGTCCGTCTGTTGTCCG
CGCATTCGGCATGGGCTGGGAAAAAACCGTTTCCCACTCGTGGACAACCCTCAAATTTTTCGGCAAACTAATCAGCGGCA
ACGCCTCCGTCAGCCATATTTCCGGACCGCTGACCATTGCCGACATTGCCGGACAGTCCGCCGAACTCGGCTTGCAAAGT
TATTTGGAATTTTTGGCACTGGTCAGCATCAGCCTCGGCGTGCTGAACCTGCTGCCCGTCCCCGTTTTGGACGGCGGCCA
CCTCGTGTTTTATACTGCCGAATGGATACGCGGCAAACCTTTGGGCGAACGCGTCCAAAACATCGGTTTGCGCTTCGGGC
TTGCCCTCATGATGCTGATGATGGCAATCGCTTTTTTCAACGACATTACCCGCCTGCTTGGCTGA

Upstream 100 bases:

>100_bases
GGGCAGATTAAGTTTACCGACATTGCCAAAACCGTCGCCCATTGTCTCGCACAAGACTTTTCAGACGGCATAGGCGACAT
AGGGGGGCTCTTGGCGCAAG

Downstream 100 bases:

>100_bases
ATTTCACGTTTCGTTATGCCGTCTGAAAGCATAACGCACCACAAGGAACTTATGATGAAACTGAAACAGATTGCTTCCGC
ACTGATGGTCTTGGGCATAT

Product: integral membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 473

Protein sequence:

>474_residues
MPGHAHKRGHLSAHCADAVRTPLSKENHLHTLLAFIFAILILVSLHEFGHYIVARLCGVKVVRFSVGFGKPFFTRKRGDT
EWCLAPIPLGGYVKMVDTREGEVSEADLPYAFDKQHPAKRIAIVAAGPLTNLALAVLLYGLSFSFGVTELRPYVGTVEPD
TIAARAGFQSGDKIQSVNGTPVADWGSAQTEIVLNLEAGKVAVGVQTASGAQTVRTIDAASTPEAGKIAKNQGYIGLMPF
KITTVAGGVEKGSPAEKAGLKPGDRLTAADGKPITSWQEWANLTRQSPGRKIALTYERAGQTHTADIRPDTVEQSDHTLI
GRVGLRPQPDRAWDAQIRRSYRPSVVRAFGMGWEKTVSHSWTTLKFFGKLISGNASVSHISGPLTIADIAGQSAELGLQS
YLEFLALVSISLGVLNLLPVPVLDGGHLVFYTAEWIRGKPLGERVQNIGLRFGLALMMLMMAIAFFNDITRLLG

Sequences:

>Translated_474_residues
MPGHAHKRGHLSAHCADAVRTPLSKENHLHTLLAFIFAILILVSLHEFGHYIVARLCGVKVVRFSVGFGKPFFTRKRGDT
EWCLAPIPLGGYVKMVDTREGEVSEADLPYAFDKQHPAKRIAIVAAGPLTNLALAVLLYGLSFSFGVTELRPYVGTVEPD
TIAARAGFQSGDKIQSVNGTPVADWGSAQTEIVLNLEAGKVAVGVQTASGAQTVRTIDAASTPEAGKIAKNQGYIGLMPF
KITTVAGGVEKGSPAEKAGLKPGDRLTAADGKPITSWQEWANLTRQSPGRKIALTYERAGQTHTADIRPDTVEQSDHTLI
GRVGLRPQPDRAWDAQIRRSYRPSVVRAFGMGWEKTVSHSWTTLKFFGKLISGNASVSHISGPLTIADIAGQSAELGLQS
YLEFLALVSISLGVLNLLPVPVLDGGHLVFYTAEWIRGKPLGERVQNIGLRFGLALMMLMMAIAFFNDITRLLG
>Mature_473_residues
PGHAHKRGHLSAHCADAVRTPLSKENHLHTLLAFIFAILILVSLHEFGHYIVARLCGVKVVRFSVGFGKPFFTRKRGDTE
WCLAPIPLGGYVKMVDTREGEVSEADLPYAFDKQHPAKRIAIVAAGPLTNLALAVLLYGLSFSFGVTELRPYVGTVEPDT
IAARAGFQSGDKIQSVNGTPVADWGSAQTEIVLNLEAGKVAVGVQTASGAQTVRTIDAASTPEAGKIAKNQGYIGLMPFK
ITTVAGGVEKGSPAEKAGLKPGDRLTAADGKPITSWQEWANLTRQSPGRKIALTYERAGQTHTADIRPDTVEQSDHTLIG
RVGLRPQPDRAWDAQIRRSYRPSVVRAFGMGWEKTVSHSWTTLKFFGKLISGNASVSHISGPLTIADIAGQSAELGLQSY
LEFLALVSISLGVLNLLPVPVLDGGHLVFYTAEWIRGKPLGERVQNIGLRFGLALMMLMMAIAFFNDITRLLG

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=457, Percent_Identity=38.2932166301969, Blast_Score=285, Evalue=7e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 51121; Mature: 50989

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS50106 PDZ ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGHAHKRGHLSAHCADAVRTPLSKENHLHTLLAFIFAILILVSLHEFGHYIVARLCGVK
CCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
VVRFSVGFGKPFFTRKRGDTEWCLAPIPLGGYVKMVDTREGEVSEADLPYAFDKQHPAKR
EEEEEECCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCE
IAIVAAGPLTNLALAVLLYGLSFSFGVTELRPYVGTVEPDTIAARAGFQSGDKIQSVNGT
EEEEECCCHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCHHHHHCCCCCCCCEECCCCC
PVADWGSAQTEIVLNLEAGKVAVGVQTASGAQTVRTIDAASTPEAGKIAKNQGYIGLMPF
CCCCCCCCCEEEEEEECCCEEEEEEEECCCCCCEEEECCCCCCCCCCEECCCCCEEEECE
KITTVAGGVEKGSPAEKAGLKPGDRLTAADGKPITSWQEWANLTRQSPGRKIALTYERAG
EEEEEECCCCCCCCHHHCCCCCCCCEECCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCC
QTHTADIRPDTVEQSDHTLIGRVGLRPQPDRAWDAQIRRSYRPSVVRAFGMGWEKTVSHS
CEEECCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCHHHHHHCCCHHHHHCCC
WTTLKFFGKLISGNASVSHISGPLTIADIAGQSAELGLQSYLEFLALVSISLGVLNLLPV
CHHHHHHHHHHCCCCCEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
PVLDGGHLVFYTAEWIRGKPLGERVQNIGLRFGLALMMLMMAIAFFNDITRLLG
CEECCCEEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
PGHAHKRGHLSAHCADAVRTPLSKENHLHTLLAFIFAILILVSLHEFGHYIVARLCGVK
CCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
VVRFSVGFGKPFFTRKRGDTEWCLAPIPLGGYVKMVDTREGEVSEADLPYAFDKQHPAKR
EEEEEECCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCE
IAIVAAGPLTNLALAVLLYGLSFSFGVTELRPYVGTVEPDTIAARAGFQSGDKIQSVNGT
EEEEECCCHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCHHHHHCCCCCCCCEECCCCC
PVADWGSAQTEIVLNLEAGKVAVGVQTASGAQTVRTIDAASTPEAGKIAKNQGYIGLMPF
CCCCCCCCCEEEEEEECCCEEEEEEEECCCCCCEEEECCCCCCCCCCEECCCCCEEEECE
KITTVAGGVEKGSPAEKAGLKPGDRLTAADGKPITSWQEWANLTRQSPGRKIALTYERAG
EEEEEECCCCCCCCHHHCCCCCCCCEECCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCC
QTHTADIRPDTVEQSDHTLIGRVGLRPQPDRAWDAQIRRSYRPSVVRAFGMGWEKTVSHS
CEEECCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCHHHHHHCCCHHHHHCCC
WTTLKFFGKLISGNASVSHISGPLTIADIAGQSAELGLQSYLEFLALVSISLGVLNLLPV
CHHHHHHHHHHCCCCCEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
PVLDGGHLVFYTAEWIRGKPLGERVQNIGLRFGLALMMLMMAIAFFNDITRLLG
CEECCCEEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]