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The map label for this gene is cdsA [H]

Identifier: 161870878

GI number: 161870878

Start: 2017675

End: 2018472

Strand: Direct

Name: cdsA [H]

Synonym: NMCC_1967

Alternate gene names: 161870878

Gene position: 2017675-2018472 (Clockwise)

Preceding gene: 161870877

Following gene: 161870879

Centisome position: 93.7

GC content: 56.27

Gene sequence:

>798_bases
ATGCTGAAACAACGGGTAATAACCGCCATGTGGCTGCTGCCGCTGATGCTGGGCATGCTGTTTTACGCGCCGCAATGGTT
GTGGGCTGCATTTTGCGGACTGATTGCCCTGATTGCCTTGTGGGAATATGCCCGTATGGGCGGTTTGTGCAAAATTAAAA
CCAACCATTACCTCGCCGCAACCTTGGTTTTCGGCGTGGTTGCCTATGCGGGCGGCTGGATGCTGCCTAATTTGGTTTGG
TATGTTGTTTTGGCATTTTGGCTCGCCGTTATGCCTTTATGGTTGAGATTCAAATGGAGGCTCAACGGCGGTTGGCAGGT
TTATGCCGTCGGCTGGCTTCTGGTCATGCCGTTTTGGTTCGCGCTCGTATCCCTGCGCCCGCATCCCGATGATGCCCTGC
CGCTGCTCGCCGTGATGGGTTTGGTGTGGGTTGCCGATATTTGCGCGTATTTCAGCGGCAAGGCGTTCGGCAAACACAAA
ATCGCACCGGCAATCAGCCCCGGCAAAAGCTGGGAAGGTGCAATCGGCGGCGCGGTTTGCGTGGCAGTGTACATGACCGC
CGTACGAAGTGCCGGCTGGCTGGCATTCGATACAGGCTGGTTCGATACCGTGTTAATCGGTTTGGTGCTGACCGTTGTCA
GCGTATGCGGCGACCTGTTGGAAAGCTGGCTCAAGCGCGCGGCGGGCATTAAAGACAGCAGCAACCTGCTGTCCGGACAC
GGCGGCGTGTTCGACCGTACCGACAGCCTGATTGCCGTTATCAGCGTCTATGCGGCGATGATGTCGGTTTTAAATTGA

Upstream 100 bases:

>100_bases
GCAAGGCTTTGGACGATGCCGTCGCTTCGTTCCAAAAACGCGAACGGCGGTTCGGACGCACCTCCGAGCAACTGCCTATC
GAACAGCAAAGGAACTGAAT

Downstream 100 bases:

>100_bases
TTCTATGCCGTCTGAAAACGCTTCAGACGGCATCCGGTATAAAGTTATCCCCATTATGACACCACAAGTCCTGACCATAT
TAGGCAGTACCGGCAGCATA

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MLKQRVITAMWLLPLMLGMLFYAPQWLWAAFCGLIALIALWEYARMGGLCKIKTNHYLAATLVFGVVAYAGGWMLPNLVW
YVVLAFWLAVMPLWLRFKWRLNGGWQVYAVGWLLVMPFWFALVSLRPHPDDALPLLAVMGLVWVADICAYFSGKAFGKHK
IAPAISPGKSWEGAIGGAVCVAVYMTAVRSAGWLAFDTGWFDTVLIGLVLTVVSVCGDLLESWLKRAAGIKDSSNLLSGH
GGVFDRTDSLIAVISVYAAMMSVLN

Sequences:

>Translated_265_residues
MLKQRVITAMWLLPLMLGMLFYAPQWLWAAFCGLIALIALWEYARMGGLCKIKTNHYLAATLVFGVVAYAGGWMLPNLVW
YVVLAFWLAVMPLWLRFKWRLNGGWQVYAVGWLLVMPFWFALVSLRPHPDDALPLLAVMGLVWVADICAYFSGKAFGKHK
IAPAISPGKSWEGAIGGAVCVAVYMTAVRSAGWLAFDTGWFDTVLIGLVLTVVSVCGDLLESWLKRAAGIKDSSNLLSGH
GGVFDRTDSLIAVISVYAAMMSVLN
>Mature_265_residues
MLKQRVITAMWLLPLMLGMLFYAPQWLWAAFCGLIALIALWEYARMGGLCKIKTNHYLAATLVFGVVAYAGGWMLPNLVW
YVVLAFWLAVMPLWLRFKWRLNGGWQVYAVGWLLVMPFWFALVSLRPHPDDALPLLAVMGLVWVADICAYFSGKAFGKHK
IAPAISPGKSWEGAIGGAVCVAVYMTAVRSAGWLAFDTGWFDTVLIGLVLTVVSVCGDLLESWLKRAAGIKDSSNLLSGH
GGVFDRTDSLIAVISVYAAMMSVLN

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=281, Percent_Identity=34.5195729537367, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI1787677, Length=112, Percent_Identity=41.0714285714286, Blast_Score=88, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 29197; Mature: 29197

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure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CCCCCCHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8654980; 10984043 [H]