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The map label for this gene is gcp [H]

Identifier: 161869418

GI number: 161869418

Start: 442660

End: 443475

Strand: Direct

Name: gcp [H]

Synonym: NMCC_0426

Alternate gene names: 161869418

Gene position: 442660-443475 (Clockwise)

Preceding gene: 161869417

Following gene: 161869420

Centisome position: 20.56

GC content: 56.74

Gene sequence:

>816_bases
TTGGGCGGTGCGTTGCTGGCGGGTTCGAGTTACGCCAATGCGCTGGCTTTAGCGTTGGACAAGCCTGTTATTCCCGTCCA
TCATTTGGAAGGACATCTGCTGTCGCCGCTGTTGGCGGAGGAAAAACCCGACTTTCCTTTTGTCGCGCTGTTGGTTTCGG
GCGGGCATACGCAGATTATGGCGGTCAGGGGCATAGGCGACTACGCGCTTTTGGGCGAGAGCGTCGATGATGCGGCGGGC
GAGGCATTCGACAAAACGGCGAAACTGCTGGGCTTGCCGTATCCGGGCGGTGCGAAACTGTCGGAACTTGCGGAATCGGG
CAGGCCCGAAGCGTTTGTTTTTCCGCGCCCGATGATTCATTCCGACGATTTGCAGATGAGTTTTTCAGGTTTGAAAACCG
CTGTTTTGACTGCCGTTGAAAAAGTGCGTGAGGCAAACGGTTCGGAAACCATTCCCGAGCAAACCCGCAACGATATTTGC
CGTGCGTTTCAAGATGCGGTAGTCGATGTGTTGGCGGCGAAAGTGAAAAAAGCCCTGTTGCAGACAGGGTTCAGAACCGT
AGTGGTCGCCGGCGGGGTCGGTGCAAACCGCAAACTCCGTGAAACTTTCGGCAATATGACGGTGCAAATCCCGACCCCAA
AAGGCAAGCCGAAACATCCGTCCGAAAAAGTCAGCGTGTTTTTCCCGCCGACGGCATACTGCACGGACAACGGTGCCATG
ATTGCCTTTGCCGGTGCGATGCACCTGGGCAAGGGCAGGGAGGTCGGTGCGTTCAATGTCCGTCCGCGCTGGCCGCTGTC
GGAAATCGTCAGATGA

Upstream 100 bases:

>100_bases
CCATATCCGCCGCCTTGTTCCGTTGACTGAAGGCTGTTTGGCGCAGGCGGGCGCATCGTATGGCGACATTGACGCGGTTG
CCTTTACGCAGGGGCCCGGT

Downstream 100 bases:

>100_bases
CAAAATGCCGTCTGAAATTGTTCAGACGGCATTTTTATTTTCGTTACGGCATTTTGTAGCGGTTGTACATAAACAGATAC
TGCGTCGGAAAACGGCGTAT

Product: O-sialoglycoprotein endopeptidase

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MGGALLAGSSYANALALALDKPVIPVHHLEGHLLSPLLAEEKPDFPFVALLVSGGHTQIMAVRGIGDYALLGESVDDAAG
EAFDKTAKLLGLPYPGGAKLSELAESGRPEAFVFPRPMIHSDDLQMSFSGLKTAVLTAVEKVREANGSETIPEQTRNDIC
RAFQDAVVDVLAAKVKKALLQTGFRTVVVAGGVGANRKLRETFGNMTVQIPTPKGKPKHPSEKVSVFFPPTAYCTDNGAM
IAFAGAMHLGKGREVGAFNVRPRWPLSEIVR

Sequences:

>Translated_271_residues
MGGALLAGSSYANALALALDKPVIPVHHLEGHLLSPLLAEEKPDFPFVALLVSGGHTQIMAVRGIGDYALLGESVDDAAG
EAFDKTAKLLGLPYPGGAKLSELAESGRPEAFVFPRPMIHSDDLQMSFSGLKTAVLTAVEKVREANGSETIPEQTRNDIC
RAFQDAVVDVLAAKVKKALLQTGFRTVVVAGGVGANRKLRETFGNMTVQIPTPKGKPKHPSEKVSVFFPPTAYCTDNGAM
IAFAGAMHLGKGREVGAFNVRPRWPLSEIVR
>Mature_270_residues
GGALLAGSSYANALALALDKPVIPVHHLEGHLLSPLLAEEKPDFPFVALLVSGGHTQIMAVRGIGDYALLGESVDDAAGE
AFDKTAKLLGLPYPGGAKLSELAESGRPEAFVFPRPMIHSDDLQMSFSGLKTAVLTAVEKVREANGSETIPEQTRNDICR
AFQDAVVDVLAAKVKKALLQTGFRTVVVAGGVGANRKLRETFGNMTVQIPTPKGKPKHPSEKVSVFFPPTAYCTDNGAMI
AFAGAMHLGKGREVGAFNVRPRWPLSEIVR

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=281, Percent_Identity=29.5373665480427, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI8923380, Length=250, Percent_Identity=29.6, Blast_Score=87, Evalue=1e-17,
Organism=Escherichia coli, GI1789445, Length=268, Percent_Identity=54.4776119402985, Blast_Score=272, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI71995670, Length=254, Percent_Identity=30.3149606299213, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17557464, Length=261, Percent_Identity=31.0344827586207, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6320099, Length=289, Percent_Identity=32.1799307958478, Blast_Score=132, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6322891, Length=271, Percent_Identity=26.1992619926199, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI20129063, Length=273, Percent_Identity=31.1355311355311, Blast_Score=121, Evalue=4e-28,
Organism=Drosophila melanogaster, GI21357207, Length=250, Percent_Identity=29.6, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 28782; Mature: 28650

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGALLAGSSYANALALALDKPVIPVHHLEGHLLSPLLAEEKPDFPFVALLVSGGHTQIM
CCCCEECCCHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHCCCCCCCEEEEEEECCCEEEE
AVRGIGDYALLGESVDDAAGEAFDKTAKLLGLPYPGGAKLSELAESGRPEAFVFPRPMIH
EEECCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCEEECCCCCCC
SDDLQMSFSGLKTAVLTAVEKVREANGSETIPEQTRNDICRAFQDAVVDVLAAKVKKALL
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTGFRTVVVAGGVGANRKLRETFGNMTVQIPTPKGKPKHPSEKVSVFFPPTAYCTDNGAM
HCCCEEEEEECCCCCCCHHHHHHCCEEEEEECCCCCCCCCCCCEEEEECCCEEECCCCCE
IAFAGAMHLGKGREVGAFNVRPRWPLSEIVR
EEEECCCCCCCCCCCCEECCCCCCCHHHHCC
>Mature Secondary Structure 
GGALLAGSSYANALALALDKPVIPVHHLEGHLLSPLLAEEKPDFPFVALLVSGGHTQIM
CCCEECCCHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHCCCCCCCEEEEEEECCCEEEE
AVRGIGDYALLGESVDDAAGEAFDKTAKLLGLPYPGGAKLSELAESGRPEAFVFPRPMIH
EEECCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCEEECCCCCCC
SDDLQMSFSGLKTAVLTAVEKVREANGSETIPEQTRNDICRAFQDAVVDVLAAKVKKALL
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTGFRTVVVAGGVGANRKLRETFGNMTVQIPTPKGKPKHPSEKVSVFFPPTAYCTDNGAM
HCCCEEEEEECCCCCCCHHHHHHCCEEEEEECCCCCCCCCCCCEEEEECCCEEECCCCCE
IAFAGAMHLGKGREVGAFNVRPRWPLSEIVR
EEEECCCCCCCCCCCCEECCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA