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The map label for this gene is qseC [H]

Identifier: 161523828

GI number: 161523828

Start: 711654

End: 713201

Strand: Reverse

Name: qseC [H]

Synonym: Bmul_0648

Alternate gene names: 161523828

Gene position: 713201-711654 (Counterclockwise)

Preceding gene: 161523829

Following gene: 161523827

Centisome position: 20.68

GC content: 71.64

Gene sequence:

>1548_bases
ATGGCCACGCCGGCCCCTTCCCGCCACCCGACCGGCGAGCCGTCGTCGGCCGCCGACGCCGCGCGCGACGCGCGCTACGC
GAACCCGTTCGCCCCGCCCGACGAAACCGACGCGCCCGAAGCCGCGCGCCCGCGCTCGCTGTTCGGCGAGATCCTCGACT
GGATGCTCGCGCCGCTGCTGCTGCTCTGGCCGATGAGCATCGCCGTCACCTACCTCGTCGCGAAGACGATCGCGAACGGC
CCGTTCGACCGCTCGCTCGAAACCAATGCGTACGTGCTCGCGCGGCAGATCCATCCGGTCAACGGCGTGGCCGAGCTGAC
GCTGCCGCAGCAGACGCGCGACTTCCTGCGCGCGGACAACATCGACAGCGTCTATTTCCAGGTGCTCGGCACGCGCGGCG
AGCTGGTGGCGGGCGAAGCCGACATGCCGCTGCCGCGCGACGAGGATCGCCCGCCGCCGGGCGTCGTCGTGTTCCGCGAC
GACCTGCTGCGCGGCAACGACGTGCGGGTCGCCTATACGACCGTCTCGCTGCCGCAGACGAGCGGCTCGCAACTCGTGCT
GGTGCAGGTCGGCGAGACGCTCGACAAGCGCAACGCGCTCGCCAACGACATCATCAAGGGCGTGATCCTGCCGCAATTCG
TGATCCTGCCGCTCGCGATCCTGCTCGTGTGGTTCGGGCTGTCGCGCGGGCTCGCGCCGCTCAACGCGCTGCAGGCGCAC
ATCCGAGCGCGGCGGCCCGACGATCTCTCGCCCGTCGAGGCGCAGCGCGCGCCGCCCGAGATCGAGCCGCTCGTCACGTC
GTTCAACGACCTGCTCGCGCGGCTCGAACAGAACATGGCGCTGCAAAAGCGCTTCATCGCCGACGCCGCCCACCAGATGA
AGACGCCGCTGGCAGGGCTGCGCACGCAGGCCGAATTCGCGCTGCGCCACCCGGTGCCGCCCGACGTGCAGCGCTCGCTC
GAACAGATCGCGACCAGTTCCGAGCAGGCCGCGCGGCTCGTCACGCAGCTGCTCGCGCTCGCGCGCGCCGAGAACCGCGC
GAGCGGGCTGACGTTCGAGCCCGTCGAGATCGCGTCGCTCGCGCGGCGCGCGGTGCGCGACTGGGTGCAGGCCGCGCTCG
CGAAGCAGATGGATCTCGGCTACGAAGGCCCGCCCGACGACGCACCGATCGACGTCGACGGCAATCCGGTGATGCTGCGC
GAAATGCTCGGCAACCTGATCGACAACGCGATCCGCTACACGCCCGAAGGCGGCCGCATCACCGTGCGCGTGCACGCCGA
CCGCACCGCGCGGCTCGCGCATCTCGAAGTCGAGGACACGGGGCCCGGCATTCCGGCCGCCGAGCGCGGCCGCGTCGTCG
AGCGCTTCTACCGGATCCTCGGCCGCGAAGGCGACGGCAGCGGGCTCGGGCTCGCGATCGTGCGCGAGATCGCCACGCAG
CACGGCGGCACGCTGACGATCGACGATCACGTCTACCAGACGGCGCCGCGCCTTGCCGGCACGCTCGTGCGCGTCAGCCT
GCCGCTGTCGGTCGCGGCCCCGGATTAA

Upstream 100 bases:

>100_bases
CGCCGACGCGCCCGCGCCGCCGCCCGCGGCGGCCGATCCGGCTTCGGCGAAGCCCGCGACAGCCGGCACGCCGCTGCGCT
GACGCCCGGCCGTCGCCGCG

Downstream 100 bases:

>100_bases
CCCTGAGGCGCGGCCGGACGCGCCGCCGTCGCGGCGTCGGAATCGGCGCTTTACCGTCCGTTCGCGACACGATCGGCGCG
CAAAGCGCGCGATTCGGCGC

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 515; Mature: 514

Protein sequence:

>515_residues
MATPAPSRHPTGEPSSAADAARDARYANPFAPPDETDAPEAARPRSLFGEILDWMLAPLLLLWPMSIAVTYLVAKTIANG
PFDRSLETNAYVLARQIHPVNGVAELTLPQQTRDFLRADNIDSVYFQVLGTRGELVAGEADMPLPRDEDRPPPGVVVFRD
DLLRGNDVRVAYTTVSLPQTSGSQLVLVQVGETLDKRNALANDIIKGVILPQFVILPLAILLVWFGLSRGLAPLNALQAH
IRARRPDDLSPVEAQRAPPEIEPLVTSFNDLLARLEQNMALQKRFIADAAHQMKTPLAGLRTQAEFALRHPVPPDVQRSL
EQIATSSEQAARLVTQLLALARAENRASGLTFEPVEIASLARRAVRDWVQAALAKQMDLGYEGPPDDAPIDVDGNPVMLR
EMLGNLIDNAIRYTPEGGRITVRVHADRTARLAHLEVEDTGPGIPAAERGRVVERFYRILGREGDGSGLGLAIVREIATQ
HGGTLTIDDHVYQTAPRLAGTLVRVSLPLSVAAPD

Sequences:

>Translated_515_residues
MATPAPSRHPTGEPSSAADAARDARYANPFAPPDETDAPEAARPRSLFGEILDWMLAPLLLLWPMSIAVTYLVAKTIANG
PFDRSLETNAYVLARQIHPVNGVAELTLPQQTRDFLRADNIDSVYFQVLGTRGELVAGEADMPLPRDEDRPPPGVVVFRD
DLLRGNDVRVAYTTVSLPQTSGSQLVLVQVGETLDKRNALANDIIKGVILPQFVILPLAILLVWFGLSRGLAPLNALQAH
IRARRPDDLSPVEAQRAPPEIEPLVTSFNDLLARLEQNMALQKRFIADAAHQMKTPLAGLRTQAEFALRHPVPPDVQRSL
EQIATSSEQAARLVTQLLALARAENRASGLTFEPVEIASLARRAVRDWVQAALAKQMDLGYEGPPDDAPIDVDGNPVMLR
EMLGNLIDNAIRYTPEGGRITVRVHADRTARLAHLEVEDTGPGIPAAERGRVVERFYRILGREGDGSGLGLAIVREIATQ
HGGTLTIDDHVYQTAPRLAGTLVRVSLPLSVAAPD
>Mature_514_residues
ATPAPSRHPTGEPSSAADAARDARYANPFAPPDETDAPEAARPRSLFGEILDWMLAPLLLLWPMSIAVTYLVAKTIANGP
FDRSLETNAYVLARQIHPVNGVAELTLPQQTRDFLRADNIDSVYFQVLGTRGELVAGEADMPLPRDEDRPPPGVVVFRDD
LLRGNDVRVAYTTVSLPQTSGSQLVLVQVGETLDKRNALANDIIKGVILPQFVILPLAILLVWFGLSRGLAPLNALQAHI
RARRPDDLSPVEAQRAPPEIEPLVTSFNDLLARLEQNMALQKRFIADAAHQMKTPLAGLRTQAEFALRHPVPPDVQRSLE
QIATSSEQAARLVTQLLALARAENRASGLTFEPVEIASLARRAVRDWVQAALAKQMDLGYEGPPDDAPIDVDGNPVMLRE
MLGNLIDNAIRYTPEGGRITVRVHADRTARLAHLEVEDTGPGIPAAERGRVVERFYRILGREGDGSGLGLAIVREIATQH
GGTLTIDDHVYQTAPRLAGTLVRVSLPLSVAAPD

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=437, Percent_Identity=29.7482837528604, Blast_Score=165, Evalue=6e-42,
Organism=Escherichia coli, GI1786783, Length=318, Percent_Identity=32.7044025157233, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI1790551, Length=289, Percent_Identity=34.6020761245675, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1790861, Length=324, Percent_Identity=30.5555555555556, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1786600, Length=224, Percent_Identity=33.0357142857143, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1788393, Length=254, Percent_Identity=29.5275590551181, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788279, Length=291, Percent_Identity=26.1168384879725, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI145693157, Length=227, Percent_Identity=27.3127753303965, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI48994928, Length=208, Percent_Identity=29.8076923076923, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790346, Length=262, Percent_Identity=29.7709923664122, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1789149, Length=224, Percent_Identity=26.7857142857143, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87082128, Length=262, Percent_Identity=29.0076335877863, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1788713, Length=260, Percent_Identity=23.8461538461538, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI87081816, Length=266, Percent_Identity=27.8195488721804, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790436, Length=249, Percent_Identity=25.3012048192771, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787374, Length=288, Percent_Identity=27.7777777777778, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787894, Length=266, Percent_Identity=28.1954887218045, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1786912, Length=238, Percent_Identity=29.4117647058824, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1789808, Length=257, Percent_Identity=27.6264591439689, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790300, Length=250, Percent_Identity=29.6, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1788549, Length=228, Percent_Identity=22.3684210526316, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 56037; Mature: 55905

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPAPSRHPTGEPSSAADAARDARYANPFAPPDETDAPEAARPRSLFGEILDWMLAPLL
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LLWPMSIAVTYLVAKTIANGPFDRSLETNAYVLARQIHPVNGVAELTLPQQTRDFLRADN
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCEEECCCHHHHHHHHHCC
IDSVYFQVLGTRGELVAGEADMPLPRDEDRPPPGVVVFRDDLLRGNDVRVAYTTVSLPQT
CHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEEEECCCC
SGSQLVLVQVGETLDKRNALANDIIKGVILPQFVILPLAILLVWFGLSRGLAPLNALQAH
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
IRARRPDDLSPVEAQRAPPEIEPLVTSFNDLLARLEQNMALQKRFIADAAHQMKTPLAGL
HHCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
RTQAEFALRHPVPPDVQRSLEQIATSSEQAARLVTQLLALARAENRASGLTFEPVEIASL
HHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
ARRAVRDWVQAALAKQMDLGYEGPPDDAPIDVDGNPVMLREMLGNLIDNAIRYTPEGGRI
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCEE
TVRVHADRTARLAHLEVEDTGPGIPAAERGRVVERFYRILGREGDGSGLGLAIVREIATQ
EEEEECCCCEEEEEEEECCCCCCCCCHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
HGGTLTIDDHVYQTAPRLAGTLVRVSLPLSVAAPD
CCCEEEECCHHHHHHHHHHHEEEEEECCEEECCCC
>Mature Secondary Structure 
ATPAPSRHPTGEPSSAADAARDARYANPFAPPDETDAPEAARPRSLFGEILDWMLAPLL
CCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LLWPMSIAVTYLVAKTIANGPFDRSLETNAYVLARQIHPVNGVAELTLPQQTRDFLRADN
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCEEECCCHHHHHHHHHCC
IDSVYFQVLGTRGELVAGEADMPLPRDEDRPPPGVVVFRDDLLRGNDVRVAYTTVSLPQT
CHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEEEECCCC
SGSQLVLVQVGETLDKRNALANDIIKGVILPQFVILPLAILLVWFGLSRGLAPLNALQAH
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
IRARRPDDLSPVEAQRAPPEIEPLVTSFNDLLARLEQNMALQKRFIADAAHQMKTPLAGL
HHCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
RTQAEFALRHPVPPDVQRSLEQIATSSEQAARLVTQLLALARAENRASGLTFEPVEIASL
HHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
ARRAVRDWVQAALAKQMDLGYEGPPDDAPIDVDGNPVMLREMLGNLIDNAIRYTPEGGRI
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCEE
TVRVHADRTARLAHLEVEDTGPGIPAAERGRVVERFYRILGREGDGSGLGLAIVREIATQ
EEEEECCCCEEEEEEEECCCCCCCCCHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
HGGTLTIDDHVYQTAPRLAGTLVRVSLPLSVAAPD
CCCEEEECCHHHHHHHHHHHEEEEEECCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]