Click here to switch to the map view.

The map label for this gene is tctD [H]

Identifier: 161523829

GI number: 161523829

Start: 713220

End: 713978

Strand: Reverse

Name: tctD [H]

Synonym: Bmul_0649

Alternate gene names: 161523829

Gene position: 713978-713220 (Counterclockwise)

Preceding gene: 161523838

Following gene: 161523828

Centisome position: 20.7

GC content: 69.43

Gene sequence:

>759_bases
ATGCGAATTCTCATCGCCGAAGACGACAGCATACTCGCGGACGGCCTCACCCGGTCACTCCGCCAATCGGGCTATGCGGT
CGACCACGTGAAGAGCGGCGTCGAGGCCGATACCGCGCTGTCGATGCAGACTTTCGACCTGCTGATCCTCGATCTCGGCC
TGCCCAAAATGTCCGGGCTCGACGTGCTGAAGCGCCTGCGCGCGCGCAATTCCAATCTCCCGGTCCTGATCCTGACCGCC
GCCGACAGCGTCGACGAGCGCGTGAAAGGGCTCGATCTCGGCGCCGACGACTACATGGCCAAGCCGTTCGCGCTGAACGA
GCTCGAGGCGCGCGTGCGCGCGCTGACGCGGCGCGGCGCCGGCGGCGGCCCGACCGTCGTGCGGCACGGCTCGCTCGCGT
TCGACCAGGTCGGCCGGATCGCCTATGCGAACGACCGCGTGCTCGATTTGTCCGCACGCGAACTCGGGCTGCTCGAAGTG
CTGCTGCAGCGGATCGGGCGCCTCGTGTCGAAGGAGCAGCTCGTCGACCATCTGTGCGAATGGGGCGAGGAAGTCAGCAA
CAACGCGATCGAAGTGTACGTGCACCGGCTGCGCAAGAAGATCGAGCCGAGCGGCGTGCGGATCGCGACCGTGCGCGGCC
TCGGCTACTGCCTCGAGAAGGTCGTGCCGGCCGCGCCCGCCGACGCGCCCGCGCCGCCGCCCGCGGCGGCCGATCCGGCT
TCGGCGAAGCCCGCGACAGCCGGCACGCCGCTGCGCTGA

Upstream 100 bases:

>100_bases
ACAGTGTTTTGTGCAAGCCCGCAATCAGGCTGCGTTGTACACGAATATTCGGAGACAGCCGTGCCGGCGCCAACGCGCTG
CCGGTCACCGGTCACGCACT

Downstream 100 bases:

>100_bases
CGCCCGGCCGTCGCCGCGATGGCCACGCCGGCCCCTTCCCGCCACCCGACCGGCGAGCCGTCGTCGGCCGCCGACGCCGC
GCGCGACGCGCGCTACGCGA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MRILIAEDDSILADGLTRSLRQSGYAVDHVKSGVEADTALSMQTFDLLILDLGLPKMSGLDVLKRLRARNSNLPVLILTA
ADSVDERVKGLDLGADDYMAKPFALNELEARVRALTRRGAGGGPTVVRHGSLAFDQVGRIAYANDRVLDLSARELGLLEV
LLQRIGRLVSKEQLVDHLCEWGEEVSNNAIEVYVHRLRKKIEPSGVRIATVRGLGYCLEKVVPAAPADAPAPPPAAADPA
SAKPATAGTPLR

Sequences:

>Translated_252_residues
MRILIAEDDSILADGLTRSLRQSGYAVDHVKSGVEADTALSMQTFDLLILDLGLPKMSGLDVLKRLRARNSNLPVLILTA
ADSVDERVKGLDLGADDYMAKPFALNELEARVRALTRRGAGGGPTVVRHGSLAFDQVGRIAYANDRVLDLSARELGLLEV
LLQRIGRLVSKEQLVDHLCEWGEEVSNNAIEVYVHRLRKKIEPSGVRIATVRGLGYCLEKVVPAAPADAPAPPPAAADPA
SAKPATAGTPLR
>Mature_252_residues
MRILIAEDDSILADGLTRSLRQSGYAVDHVKSGVEADTALSMQTFDLLILDLGLPKMSGLDVLKRLRARNSNLPVLILTA
ADSVDERVKGLDLGADDYMAKPFALNELEARVRALTRRGAGGGPTVVRHGSLAFDQVGRIAYANDRVLDLSARELGLLEV
LLQRIGRLVSKEQLVDHLCEWGEEVSNNAIEVYVHRLRKKIEPSGVRIATVRGLGYCLEKVVPAAPADAPAPPPAAADPA
SAKPATAGTPLR

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=44.954128440367, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=42.6605504587156, Blast_Score=169, Evalue=1e-43,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=38.7387387387387, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=38.8392857142857, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=36.6515837104072, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=35.2678571428571, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1786599, Length=222, Percent_Identity=33.7837837837838, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=34.061135371179, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1788394, Length=230, Percent_Identity=31.304347826087, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1786911, Length=221, Percent_Identity=31.6742081447964, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=33.3333333333333, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788713, Length=115, Percent_Identity=40, Blast_Score=80, Evalue=9e-17,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=28.3185840707965, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=29.2035398230088, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790299, Length=144, Percent_Identity=32.6388888888889, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790437, Length=108, Percent_Identity=38.8888888888889, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=27.2340425531915, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=31.7757009345794, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787487, Length=114, Percent_Identity=34.2105263157895, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27070; Mature: 27070

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILIAEDDSILADGLTRSLRQSGYAVDHVKSGVEADTALSMQTFDLLILDLGLPKMSGL
CEEEEECCCCHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHEECCCCCCCHH
DVLKRLRARNSNLPVLILTAADSVDERVKGLDLGADDYMAKPFALNELEARVRALTRRGA
HHHHHHHHCCCCCCEEEEECCCCHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHCCC
GGGPTVVRHGSLAFDQVGRIAYANDRVLDLSARELGLLEVLLQRIGRLVSKEQLVDHLCE
CCCCCEEECCCCCHHHHCCEEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WGEEVSNNAIEVYVHRLRKKIEPSGVRIATVRGLGYCLEKVVPAAPADAPAPPPAAADPA
HHHHHCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
SAKPATAGTPLR
CCCCCCCCCCCC
>Mature Secondary Structure
MRILIAEDDSILADGLTRSLRQSGYAVDHVKSGVEADTALSMQTFDLLILDLGLPKMSGL
CEEEEECCCCHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHEECCCCCCCHH
DVLKRLRARNSNLPVLILTAADSVDERVKGLDLGADDYMAKPFALNELEARVRALTRRGA
HHHHHHHHCCCCCCEEEEECCCCHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHCCC
GGGPTVVRHGSLAFDQVGRIAYANDRVLDLSARELGLLEVLLQRIGRLVSKEQLVDHLCE
CCCCCEEECCCCCHHHHCCEEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WGEEVSNNAIEVYVHRLRKKIEPSGVRIATVRGLGYCLEKVVPAAPADAPAPPPAAADPA
HHHHHCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
SAKPATAGTPLR
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]