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The map label for this gene is csgA [H]

Identifier: 161523557

GI number: 161523557

Start: 414586

End: 415263

Strand: Reverse

Name: csgA [H]

Synonym: Bmul_0377

Alternate gene names: 161523557

Gene position: 415263-414586 (Counterclockwise)

Preceding gene: 161523558

Following gene: 161523556

Centisome position: 12.04

GC content: 69.76

Gene sequence:

>678_bases
ATGAAAACCGTACTGATCGTCGGCGCATCGCGCGGCCTCGGCCGCGAGTTCGTCCGGCAATACCAGCGCGACGGCTGGAA
CGTGATCGCGACCGCACGCGACGACGCGTCGCTCGCAGCGCTGCGCGCGCTCGGCGCACACGCGCATGCGCTCGACATCA
CGCAGCCCGAGCAGATCGCCGCGCTCGGCTGGAAGCTCGACGGCGAACGGCTCGACGTGGCCGTCGTCGTATCGGGCGTG
TACGGGCCGCGCACCGAAGGCGTCGAAACGATCGCCTCCGACGATTTCGACACCGTCATGCATACGAACGTGCGCGGGCC
GATGCAGTTGCTGCCGATCCTGCTGCCGCTCGTCGAAGACGCGCGCGGCGTGCTCGCCGTCGTGTCGAGCCGGATGGGCA
GCATCTCGGAGGCGACCGGCACGACGGGGTGGCTCTATCGCGCGAGCAAGGCCGCACTGAACGACGTCCTGCGCATCGCG
TCGCTGCAGACGCGCCATGCCGCCTGCATTTCGCTGCACCCGGGCTGGGTGCGCACCGACATGGGCGGCGCGCAGGCCGC
GCTCGATCCCGCGACGAGCGTGACCGGCATGCGCCGCGTCATTGCCGAGGCCGGCGCCGACGTCTCGCAGTCGAACGGCC
GATTCTTCCAGTACGACGGCGTAGAGCTGAGCTGGTGA

Upstream 100 bases:

>100_bases
TGCTGAGCGCCGAACGCGCGCGTCGCGATGCACCCATCGCGTCGCGCGCCGCGATCGTCCCGCGACGCGCCGGCATCGCA
CCGTACAAGGAGCGGCGAAC

Downstream 100 bases:

>100_bases
TCGCCATTCACAACGCCTCGTCGTTAATTCCTGTTACGCATGATTCCGAACCCACCTGATACCTGCCCGTGCGGCGGCGC
GTCCCCTGCAGCGGCCGGCA

Product: short chain dehydrogenase

Products: NA

Alternate protein names: C signal [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MKTVLIVGASRGLGREFVRQYQRDGWNVIATARDDASLAALRALGAHAHALDITQPEQIAALGWKLDGERLDVAVVVSGV
YGPRTEGVETIASDDFDTVMHTNVRGPMQLLPILLPLVEDARGVLAVVSSRMGSISEATGTTGWLYRASKAALNDVLRIA
SLQTRHAACISLHPGWVRTDMGGAQAALDPATSVTGMRRVIAEAGADVSQSNGRFFQYDGVELSW

Sequences:

>Translated_225_residues
MKTVLIVGASRGLGREFVRQYQRDGWNVIATARDDASLAALRALGAHAHALDITQPEQIAALGWKLDGERLDVAVVVSGV
YGPRTEGVETIASDDFDTVMHTNVRGPMQLLPILLPLVEDARGVLAVVSSRMGSISEATGTTGWLYRASKAALNDVLRIA
SLQTRHAACISLHPGWVRTDMGGAQAALDPATSVTGMRRVIAEAGADVSQSNGRFFQYDGVELSW
>Mature_225_residues
MKTVLIVGASRGLGREFVRQYQRDGWNVIATARDDASLAALRALGAHAHALDITQPEQIAALGWKLDGERLDVAVVVSGV
YGPRTEGVETIASDDFDTVMHTNVRGPMQLLPILLPLVEDARGVLAVVSSRMGSISEATGTTGWLYRASKAALNDVLRIA
SLQTRHAACISLHPGWVRTDMGGAQAALDPATSVTGMRRVIAEAGADVSQSNGRFFQYDGVELSW

Specific function: Cell-cell signaling protein required for fruiting body morphogenesis. Necessary for cellular aggregation, for spore differentiation, and for gene expression that is initiated after 6 hour of starvation [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To yeast YKL071W [H]

Homologues:

Organism=Caenorhabditis elegans, GI17558994, Length=242, Percent_Identity=28.9256198347107, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17559962, Length=218, Percent_Identity=30.2752293577982, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI193207563, Length=212, Percent_Identity=29.7169811320755, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17532177, Length=242, Percent_Identity=28.9256198347107, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17558990, Length=244, Percent_Identity=27.8688524590164, Blast_Score=68, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322779, Length=248, Percent_Identity=27.0161290322581, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24640547, Length=251, Percent_Identity=29.4820717131474, Blast_Score=98, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 24052; Mature: 24052

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTVLIVGASRGLGREFVRQYQRDGWNVIATARDDASLAALRALGAHAHALDITQPEQIA
CCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCEEECCCCCHHHH
ALGWKLDGERLDVAVVVSGVYGPRTEGVETIASDDFDTVMHTNVRGPMQLLPILLPLVED
HCCEEECCCEEEEEEEEECCCCCCCCCHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHH
ARGVLAVVSSRMGSISEATGTTGWLYRASKAALNDVLRIASLQTRHAACISLHPGWVRTD
HHHHHHHHHHHCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEC
MGGAQAALDPATSVTGMRRVIAEAGADVSQSNGRFFQYDGVELSW
CCCCCHHCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCEEECC
>Mature Secondary Structure
MKTVLIVGASRGLGREFVRQYQRDGWNVIATARDDASLAALRALGAHAHALDITQPEQIA
CCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCEEECCCCCHHHH
ALGWKLDGERLDVAVVVSGVYGPRTEGVETIASDDFDTVMHTNVRGPMQLLPILLPLVED
HCCEEECCCEEEEEEEEECCCCCCCCCHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHH
ARGVLAVVSSRMGSISEATGTTGWLYRASKAALNDVLRIASLQTRHAACISLHPGWVRTD
HHHHHHHHHHHCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEC
MGGAQAALDPATSVTGMRRVIAEAGADVSQSNGRFFQYDGVELSW
CCCCCHHCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2152896; 2107980; 2118510; 1372277 [H]