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The map label for this gene is can [H]

Identifier: 161523558

GI number: 161523558

Start: 415358

End: 416143

Strand: Reverse

Name: can [H]

Synonym: Bmul_0378

Alternate gene names: 161523558

Gene position: 416143-415358 (Counterclockwise)

Preceding gene: 161523559

Following gene: 161523557

Centisome position: 12.07

GC content: 67.05

Gene sequence:

>786_bases
ATGACGGACACCACCACGATGAATACCCAAGATCACCCGCTTTCCCACCTGTTCGACAACAACGACGCCTGGGTCAAGCG
CCAGCTCGCCGAAGACCCGCAGTTCTTCGCGCGCCTCGCCGACCAGCAGGCGCCGGAATACCTGTGGATCGGCTGTTCCG
ACTCGCGCGTGCCGGCGAACCAGATCATCGGCCTGCCGCCGGGCGAAGTGTTCGTCCACCGCAACATCGCGAACGTCGTC
GTCCACACCGATCTGAACTGCCTGTCGGTGATCCAGTTCGCGGTCGACATCCTGCGCGTGAAGCACATCATGGTGGTCGG
CCACTACGGCTGCTCCGGCGTGAACGCGGCGCTGCACAACCGCCGCGTCGGCCTCGCCGACAACTGGCTGCACCACGTGC
AGGACGTGCGCGAGCGCCACGCGGCGCTGCTCGACGAATGGCCGGTCGGCGAAGCACGCTATCGCCGCCTGATCGAGCTG
AACGCGATCGAGCAGGTCGTCAACGTCTGCCGCACGACGATCGTCAACGACGCATGGGCGCGCGGCCAGTCGCTGACCGT
CCACGCACTCGTGTACGGCGTGCACGACGGCCGGATGCGCAACCTCGGGATGGCCGTGTCGAACTTCGATTCGCTCGAGG
AGACGTATCGGCGCTGCGTCGCGTCGCTGACCGCGCGCGGCGAACACGCGCCGGACAACGACATCATCGCGGCCGACGCC
GCGCGGCTCGATGCGGTCGCGCAGTCGGTCGCCGATACGCTGAAGCACGGCGACGGCAACTGCTGA

Upstream 100 bases:

>100_bases
TCCGGAGCGCTTTCGCGCGACGGACGAGCGTGCGCCGGCGCGCGGCGCGCAGCGTGCGGCCTGATGTGTTTCACCCGAAC
CCGATATCGAACGATTCACG

Downstream 100 bases:

>100_bases
GCGCCGAACGCGCGCGTCGCGATGCACCCATCGCGTCGCGCGCCGCGATCGTCCCGCGACGCGCCGGCATCGCACCGTAC
AAGGAGCGGCGAACATGAAA

Product: carbonate dehydratase

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MTDTTTMNTQDHPLSHLFDNNDAWVKRQLAEDPQFFARLADQQAPEYLWIGCSDSRVPANQIIGLPPGEVFVHRNIANVV
VHTDLNCLSVIQFAVDILRVKHIMVVGHYGCSGVNAALHNRRVGLADNWLHHVQDVRERHAALLDEWPVGEARYRRLIEL
NAIEQVVNVCRTTIVNDAWARGQSLTVHALVYGVHDGRMRNLGMAVSNFDSLEETYRRCVASLTARGEHAPDNDIIAADA
ARLDAVAQSVADTLKHGDGNC

Sequences:

>Translated_261_residues
MTDTTTMNTQDHPLSHLFDNNDAWVKRQLAEDPQFFARLADQQAPEYLWIGCSDSRVPANQIIGLPPGEVFVHRNIANVV
VHTDLNCLSVIQFAVDILRVKHIMVVGHYGCSGVNAALHNRRVGLADNWLHHVQDVRERHAALLDEWPVGEARYRRLIEL
NAIEQVVNVCRTTIVNDAWARGQSLTVHALVYGVHDGRMRNLGMAVSNFDSLEETYRRCVASLTARGEHAPDNDIIAADA
ARLDAVAQSVADTLKHGDGNC
>Mature_260_residues
TDTTTMNTQDHPLSHLFDNNDAWVKRQLAEDPQFFARLADQQAPEYLWIGCSDSRVPANQIIGLPPGEVFVHRNIANVVV
HTDLNCLSVIQFAVDILRVKHIMVVGHYGCSGVNAALHNRRVGLADNWLHHVQDVRERHAALLDEWPVGEARYRRLIELN
AIEQVVNVCRTTIVNDAWARGQSLTVHALVYGVHDGRMRNLGMAVSNFDSLEETYRRCVASLTARGEHAPDNDIIAADAA
RLDAVAQSVADTLKHGDGNC

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=210, Percent_Identity=52.3809523809524, Blast_Score=245, Evalue=2e-66,
Organism=Escherichia coli, GI1786534, Length=212, Percent_Identity=27.3584905660377, Blast_Score=70, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324292, Length=212, Percent_Identity=27.3584905660377, Blast_Score=85, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 29052; Mature: 28921

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTTTMNTQDHPLSHLFDNNDAWVKRQLAEDPQFFARLADQQAPEYLWIGCSDSRVPAN
CCCCCCCCCCCCCHHHHHCCCHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCCCCHH
QIIGLPPGEVFVHRNIANVVVHTDLNCLSVIQFAVDILRVKHIMVVGHYGCSGVNAALHN
HEECCCCCCEEEECCHHHEEEECCCHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHC
RRVGLADNWLHHVQDVRERHAALLDEWPVGEARYRRLIELNAIEQVVNVCRTTIVNDAWA
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGQSLTVHALVYGVHDGRMRNLGMAVSNFDSLEETYRRCVASLTARGEHAPDNDIIAADA
CCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHH
ARLDAVAQSVADTLKHGDGNC
HHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TDTTTMNTQDHPLSHLFDNNDAWVKRQLAEDPQFFARLADQQAPEYLWIGCSDSRVPAN
CCCCCCCCCCCCHHHHHCCCHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCCCCHH
QIIGLPPGEVFVHRNIANVVVHTDLNCLSVIQFAVDILRVKHIMVVGHYGCSGVNAALHN
HEECCCCCCEEEECCHHHEEEECCCHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHC
RRVGLADNWLHHVQDVRERHAALLDEWPVGEARYRRLIELNAIEQVVNVCRTTIVNDAWA
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGQSLTVHALVYGVHDGRMRNLGMAVSNFDSLEETYRRCVASLTARGEHAPDNDIIAADA
CCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHH
ARLDAVAQSVADTLKHGDGNC
HHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10493123 [H]