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The map label for this gene is pgl [H]

Identifier: 160902595

GI number: 160902595

Start: 1214857

End: 1215555

Strand: Direct

Name: pgl [H]

Synonym: Pmob_1134

Alternate gene names: 160902595

Gene position: 1214857-1215555 (Clockwise)

Preceding gene: 160902594

Following gene: 160902601

Centisome position: 56.0

GC content: 32.19

Gene sequence:

>699_bases
ATGAAAGCAAAATTTTTTGATGATCCCGAAACGTTTCACAATGAAGCTGTAAATTTAATTTATAAGCTATATGAAGAGAG
CATAGAAAAAAATAAACTATTCACCTTAATGCTCTCAGGCGGAAGAACACCACTTCCAATTTACGAAAAATTGGCATCTG
AGTACAAAGATAAAATAAATTGGGAGAAGGTCCACATTTTTTGGGGAGACGAAAGATACGTCGATCAAAAAAGTGAAGAC
AGTAATTACAAATGGGCACACGATTTGCTAATAAGCAAAATTAATATTCCAACAAATAATGTACATAGGATAAAAACAGA
ACTACCTATAGAAAAAGCATCACAAGAGTGCGAAAAAGAGATAATCAATTTTTTTGGAGAACAAAATCCCCTTTTTGATC
TGATATTACTAGGCATAGGAGAAGATGGCCACACGGTATCTTTGTTCCCTTCAAGTGACACTTTAAAAGAAAACAAAAAG
CTATTCACAGTCACACCACCTTCTGGAACACCTAAAGTACCAAGAATTACCGCCACTTACAAATTGTTGAACAATGCAAG
AAATATTCTTTTTCTAAGTTCATACAAAAGAAAAGAGCAGGTAATAGATGAAATCCTAAACAACCCAAAGATAGCAGAAG
AAAAATATCCTGCTGCAAAAATAAAAGTTAAAAATACTTATTTTTTTATAAAAATATAG

Upstream 100 bases:

>100_bases
TTATACAAAGCTGGTACCTGGGGACCAAAAGAATCTTTTGAACTATTATCAAAAGACAACAGAAGTTGGCGTAACTTAGA
CTTTGAAAGCGAGAATCTGT

Downstream 100 bases:

>100_bases
GGACTGTTTTACAGTCCCTATTAATTTAATAATTATCAAAAGCAAAGATCTCTTTGTATATGTAGAAGGGAGAGACTAGC
TAAAATTCTGCAACCATTGA

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MKAKFFDDPETFHNEAVNLIYKLYEESIEKNKLFTLMLSGGRTPLPIYEKLASEYKDKINWEKVHIFWGDERYVDQKSED
SNYKWAHDLLISKINIPTNNVHRIKTELPIEKASQECEKEIINFFGEQNPLFDLILLGIGEDGHTVSLFPSSDTLKENKK
LFTVTPPSGTPKVPRITATYKLLNNARNILFLSSYKRKEQVIDEILNNPKIAEEKYPAAKIKVKNTYFFIKI

Sequences:

>Translated_232_residues
MKAKFFDDPETFHNEAVNLIYKLYEESIEKNKLFTLMLSGGRTPLPIYEKLASEYKDKINWEKVHIFWGDERYVDQKSED
SNYKWAHDLLISKINIPTNNVHRIKTELPIEKASQECEKEIINFFGEQNPLFDLILLGIGEDGHTVSLFPSSDTLKENKK
LFTVTPPSGTPKVPRITATYKLLNNARNILFLSSYKRKEQVIDEILNNPKIAEEKYPAAKIKVKNTYFFIKI
>Mature_232_residues
MKAKFFDDPETFHNEAVNLIYKLYEESIEKNKLFTLMLSGGRTPLPIYEKLASEYKDKINWEKVHIFWGDERYVDQKSED
SNYKWAHDLLISKINIPTNNVHRIKTELPIEKASQECEKEIINFFGEQNPLFDLILLGIGEDGHTVSLFPSSDTLKENKK
LFTVTPPSGTPKVPRITATYKLLNNARNILFLSSYKRKEQVIDEILNNPKIAEEKYPAAKIKVKNTYFFIKI

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI6912586, Length=198, Percent_Identity=34.8484848484849, Blast_Score=104, Evalue=7e-23,
Organism=Homo sapiens, GI52145310, Length=236, Percent_Identity=26.6949152542373, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI115533060, Length=205, Percent_Identity=29.2682926829268, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI115533058, Length=205, Percent_Identity=29.2682926829268, Blast_Score=87, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6321957, Length=209, Percent_Identity=28.7081339712919, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6319918, Length=193, Percent_Identity=32.6424870466321, Blast_Score=78, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6324362, Length=191, Percent_Identity=32.4607329842932, Blast_Score=75, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6321687, Length=220, Percent_Identity=26.8181818181818, Blast_Score=69, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24641119, Length=206, Percent_Identity=33.0097087378641, Blast_Score=93, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900
- InterPro:   IPR006148 [H]

Pfam domain/function: PF01182 Glucosamine_iso [H]

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 27005; Mature: 27005

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAKFFDDPETFHNEAVNLIYKLYEESIEKNKLFTLMLSGGRTPLPIYEKLASEYKDKIN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCC
WEKVHIFWGDERYVDQKSEDSNYKWAHDLLISKINIPTNNVHRIKTELPIEKASQECEKE
EEEEEEEECCCCCCCCCCCCCCCHHHHHHHHEEECCCCCCCEEEEECCCHHHHHHHHHHH
IINFFGEQNPLFDLILLGIGEDGHTVSLFPSSDTLKENKKLFTVTPPSGTPKVPRITATY
HHHHHCCCCCCEEEEEEEECCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCCCHHHHH
KLLNNARNILFLSSYKRKEQVIDEILNNPKIAEEKYPAAKIKVKNTYFFIKI
HHHHCCCCEEEEECHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECEEEEEEC
>Mature Secondary Structure
MKAKFFDDPETFHNEAVNLIYKLYEESIEKNKLFTLMLSGGRTPLPIYEKLASEYKDKIN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCC
WEKVHIFWGDERYVDQKSEDSNYKWAHDLLISKINIPTNNVHRIKTELPIEKASQECEKE
EEEEEEEECCCCCCCCCCCCCCCHHHHHHHHEEECCCCCCCEEEEECCCHHHHHHHHHHH
IINFFGEQNPLFDLILLGIGEDGHTVSLFPSSDTLKENKKLFTVTPPSGTPKVPRITATY
HHHHHCCCCCCEEEEEEEECCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCCCHHHHH
KLLNNARNILFLSSYKRKEQVIDEILNNPKIAEEKYPAAKIKVKNTYFFIKI
HHHHCCCCEEEEECHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]