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The map label for this gene is rnr [H]

Identifier: 160902437

GI number: 160902437

Start: 1032767

End: 1034980

Strand: Direct

Name: rnr [H]

Synonym: Pmob_0973

Alternate gene names: 160902437

Gene position: 1032767-1034980 (Clockwise)

Preceding gene: 160902436

Following gene: 160902442

Centisome position: 47.6

GC content: 34.28

Gene sequence:

>2214_bases
ATGAATGAAGACAACTTAGAAAAACAAATATTAGAAATAATAGACAAAAATCCTACGATACAAAAAGAACTATATGAAAG
CCTAAATGCACTTGAAAAATCGGAAAAGGCTCAAATTAGAAAAATACTAAATAAACTCCTAAGTGAAGGGAAAATAATTA
AAGATTCACAAAACCAATACAGAAAATTAGATGAAAACATGGCTGTCGGAACTATCGAATTCACCAAAAGTGGAAATATG
GCTTTTGTTCAATGCTCTGATGGAAGCGAAATTGCTGTAAAGGTTGAAAATTCTGGAATCAGTTTACATAAAGATTTAGT
TTTGGTTGAAATAATAGGGAAATGGCGTGATTTAAAAGAAGGTAGGGTAGTTAGAATATTAAAAAGAGAGTTAAAATATG
TAGTGGGTGAGTTCGTAAGAAAAGGAATTTTTGGATTCGTTATACCCATTGATGCAAAAATAAATACAGATTTTTACGTA
GCCCCAGAAGGTATAGGAAAGGCTAAAAATGGTCAAATAGTGAAAGCAAAAATAACAAAATATCAATCTCCCACGAAAAA
GCCAGAGGTCGAGATAGTCGATGTCCTTGGGGACAAAGATGACCCTTCCATTGATTTGCCAATAGTGATCTTCAAACATG
GTTTACCTGAACCTGGTTATTTTCCTCCAAAGGTGTTACAAGAGGCTAAAGAACTTCCAAAAAAACTTTCTGAAAATGAA
ATTAATGGCAGAAAAGATTTTAGAAAAGAAACCATATTTACTATCGATGGTGATACAGCAAAAGATTTTGATGATGCCGT
TGGTATAAAAAAGTTAGATAACGGCAATTATTTACTTGGGGTGCATATAGCAGATGTATCTCATTATGTGAAAAGCAACA
GTGCTCTTGATAGAGAAGCATACAAACGAGGTACAAGCGTTTATTTAATCGACACGGTTATTCCAATGCTTCCATTTGAG
TTATCCAACTGGATATGTTCTTTGGTTGAAGGTGAAGATAGATTGACAATGTCTCTCCTGATGGAAATTGACCCTTATGG
GAACTTGGTAAACTCAAAAATATACAACGGAGTAATAAGAAGTGCCAAGAGGTTGACCTATAGAAAAGTTAATGAACTCC
TATCTGACAATTGTAGTGAAGAAGTAAAAAAAGAGATAGAGTTTTTAAAACCAGAGCTTGAGATGATGAGAGAATTAATG
GAATTACTTTCTGAAAAGAGAAAAGAAAGAGGTTCAATAATCGACATAGAAAGCAATGAAGTACACTTTGAATTCGATGA
AAAGGGATATGTAAAAGATATCATCCCTGTGGAAAGAGGCCTATCAGAAAAAATGATTGAAGAGTTCATGGTCCTGGCCA
ACGAAACAGTTGCTTCATACTTTGATGTTCAAGGTTTGCCTTTTATCTATAGAATCCACGAAAATCCGGATCCTGATGTA
TTGCTTCAGTTACGAAATTATCTGGACATGTTGGGAATAAATGTAAAATTTCCTCAAAATATTCATCCGAAGGTCCTACA
GGAAATATTGGAAAAAACAAAGAACCATCCTTTAAGTAAAAATATTCAGATGATGCTTGTTAGATCTATGAAAAGGGCGT
TGTACTCCGAGGAAAACGTAGGGCATTTTGGTCTTGCTTCATCATCCTATACACATTTCACATCACCAATAAGAAGATAT
CCTGACTTAGTGGTTCATAGATTGTTGAAAGAGTTCATCAAATATAAAGGAACCCTTTCAAAAAAAGAAATAAAGAAGTA
TTCCGAAATGCTTCCTGAAATAGCTAAAAATTCTTCTGAAATGGAAAGAGTCGCAGACCAAGCCGAGTGGGATCTAATAG
ATATGAAAAAAGTTGAATACATTTCAAGACATATAGGAGAAGTCTTTTGGGTGTACATAACAGGCGTCACAAGGTTTGGC
TTATTCGTAGAAATCCCCCAAAAGATGATAAGTGGATTGATACATATATCAGAGTTGAGCGATGATTATTATATCTACGA
TGAACGTGACAATACGTTGAAAGGTGAAAGAACCGGCAACGTTTATAGGATCGGAGACAAGTTACAAGCCAAAGTGGTAA
GAGCGGATAAAATCGGAACTGAAGTAGATTTTATCCCATATACGGAAGATGATTTTGAAAAATTGAAAAGGGAACATCCC
CATGCCAAAATAAAAGTTAACAAAAAAAATAAGAAAAAAAGGAAAAAATCGTAA

Upstream 100 bases:

>100_bases
TAAGTTTAGAAACAAGATTTTGATTTAAAAGGGTTACAGGGGTGCTGAAATAAGTTTTAGCTTTTTTAAAAAGTATAATT
ACATTGAAAGGGGGTAAAAT

Downstream 100 bases:

>100_bases
TTCACTTCCAAATCTCTGGTTCAACCTGTAGATCAACATTGTATTTGTCTTTTACAATACGTTTCACATACTCAATTAAT
GAAATCACATCCTTGAAAGT

Product: ribonuclease R

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 737; Mature: 737

Protein sequence:

>737_residues
MNEDNLEKQILEIIDKNPTIQKELYESLNALEKSEKAQIRKILNKLLSEGKIIKDSQNQYRKLDENMAVGTIEFTKSGNM
AFVQCSDGSEIAVKVENSGISLHKDLVLVEIIGKWRDLKEGRVVRILKRELKYVVGEFVRKGIFGFVIPIDAKINTDFYV
APEGIGKAKNGQIVKAKITKYQSPTKKPEVEIVDVLGDKDDPSIDLPIVIFKHGLPEPGYFPPKVLQEAKELPKKLSENE
INGRKDFRKETIFTIDGDTAKDFDDAVGIKKLDNGNYLLGVHIADVSHYVKSNSALDREAYKRGTSVYLIDTVIPMLPFE
LSNWICSLVEGEDRLTMSLLMEIDPYGNLVNSKIYNGVIRSAKRLTYRKVNELLSDNCSEEVKKEIEFLKPELEMMRELM
ELLSEKRKERGSIIDIESNEVHFEFDEKGYVKDIIPVERGLSEKMIEEFMVLANETVASYFDVQGLPFIYRIHENPDPDV
LLQLRNYLDMLGINVKFPQNIHPKVLQEILEKTKNHPLSKNIQMMLVRSMKRALYSEENVGHFGLASSSYTHFTSPIRRY
PDLVVHRLLKEFIKYKGTLSKKEIKKYSEMLPEIAKNSSEMERVADQAEWDLIDMKKVEYISRHIGEVFWVYITGVTRFG
LFVEIPQKMISGLIHISELSDDYYIYDERDNTLKGERTGNVYRIGDKLQAKVVRADKIGTEVDFIPYTEDDFEKLKREHP
HAKIKVNKKNKKKRKKS

Sequences:

>Translated_737_residues
MNEDNLEKQILEIIDKNPTIQKELYESLNALEKSEKAQIRKILNKLLSEGKIIKDSQNQYRKLDENMAVGTIEFTKSGNM
AFVQCSDGSEIAVKVENSGISLHKDLVLVEIIGKWRDLKEGRVVRILKRELKYVVGEFVRKGIFGFVIPIDAKINTDFYV
APEGIGKAKNGQIVKAKITKYQSPTKKPEVEIVDVLGDKDDPSIDLPIVIFKHGLPEPGYFPPKVLQEAKELPKKLSENE
INGRKDFRKETIFTIDGDTAKDFDDAVGIKKLDNGNYLLGVHIADVSHYVKSNSALDREAYKRGTSVYLIDTVIPMLPFE
LSNWICSLVEGEDRLTMSLLMEIDPYGNLVNSKIYNGVIRSAKRLTYRKVNELLSDNCSEEVKKEIEFLKPELEMMRELM
ELLSEKRKERGSIIDIESNEVHFEFDEKGYVKDIIPVERGLSEKMIEEFMVLANETVASYFDVQGLPFIYRIHENPDPDV
LLQLRNYLDMLGINVKFPQNIHPKVLQEILEKTKNHPLSKNIQMMLVRSMKRALYSEENVGHFGLASSSYTHFTSPIRRY
PDLVVHRLLKEFIKYKGTLSKKEIKKYSEMLPEIAKNSSEMERVADQAEWDLIDMKKVEYISRHIGEVFWVYITGVTRFG
LFVEIPQKMISGLIHISELSDDYYIYDERDNTLKGERTGNVYRIGDKLQAKVVRADKIGTEVDFIPYTEDDFEKLKREHP
HAKIKVNKKNKKKRKKS
>Mature_737_residues
MNEDNLEKQILEIIDKNPTIQKELYESLNALEKSEKAQIRKILNKLLSEGKIIKDSQNQYRKLDENMAVGTIEFTKSGNM
AFVQCSDGSEIAVKVENSGISLHKDLVLVEIIGKWRDLKEGRVVRILKRELKYVVGEFVRKGIFGFVIPIDAKINTDFYV
APEGIGKAKNGQIVKAKITKYQSPTKKPEVEIVDVLGDKDDPSIDLPIVIFKHGLPEPGYFPPKVLQEAKELPKKLSENE
INGRKDFRKETIFTIDGDTAKDFDDAVGIKKLDNGNYLLGVHIADVSHYVKSNSALDREAYKRGTSVYLIDTVIPMLPFE
LSNWICSLVEGEDRLTMSLLMEIDPYGNLVNSKIYNGVIRSAKRLTYRKVNELLSDNCSEEVKKEIEFLKPELEMMRELM
ELLSEKRKERGSIIDIESNEVHFEFDEKGYVKDIIPVERGLSEKMIEEFMVLANETVASYFDVQGLPFIYRIHENPDPDV
LLQLRNYLDMLGINVKFPQNIHPKVLQEILEKTKNHPLSKNIQMMLVRSMKRALYSEENVGHFGLASSSYTHFTSPIRRY
PDLVVHRLLKEFIKYKGTLSKKEIKKYSEMLPEIAKNSSEMERVADQAEWDLIDMKKVEYISRHIGEVFWVYITGVTRFG
LFVEIPQKMISGLIHISELSDDYYIYDERDNTLKGERTGNVYRIGDKLQAKVVRADKIGTEVDFIPYTEDDFEKLKREHP
HAKIKVNKKNKKKRKKS

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014623, Length=593, Percent_Identity=29.0050590219224, Blast_Score=199, Evalue=6e-51,
Organism=Homo sapiens, GI190014625, Length=593, Percent_Identity=29.0050590219224, Blast_Score=199, Evalue=8e-51,
Organism=Homo sapiens, GI134288890, Length=373, Percent_Identity=33.7801608579088, Blast_Score=189, Evalue=1e-47,
Organism=Homo sapiens, GI19115966, Length=539, Percent_Identity=30.4267161410019, Blast_Score=189, Evalue=1e-47,
Organism=Homo sapiens, GI219521928, Length=539, Percent_Identity=30.4267161410019, Blast_Score=188, Evalue=2e-47,
Organism=Homo sapiens, GI156105695, Length=136, Percent_Identity=31.6176470588235, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI156105693, Length=133, Percent_Identity=32.3308270676692, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI87082383, Length=709, Percent_Identity=34.8377997179126, Blast_Score=395, Evalue=1e-111,
Organism=Escherichia coli, GI1787542, Length=412, Percent_Identity=28.1553398058252, Blast_Score=130, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI212645896, Length=505, Percent_Identity=29.3069306930693, Blast_Score=171, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17553506, Length=460, Percent_Identity=28.9130434782609, Blast_Score=161, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6324552, Length=463, Percent_Identity=32.3974082073434, Blast_Score=186, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6320499, Length=411, Percent_Identity=23.8442822384428, Blast_Score=94, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6323943, Length=436, Percent_Identity=25.2293577981651, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24649634, Length=588, Percent_Identity=28.2312925170068, Blast_Score=209, Evalue=5e-54,
Organism=Drosophila melanogaster, GI19922976, Length=544, Percent_Identity=29.7794117647059, Blast_Score=178, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24654597, Length=544, Percent_Identity=29.7794117647059, Blast_Score=178, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24654592, Length=544, Percent_Identity=29.7794117647059, Blast_Score=178, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805 [H]

Pfam domain/function: PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 84962; Mature: 84962

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEDNLEKQILEIIDKNPTIQKELYESLNALEKSEKAQIRKILNKLLSEGKIIKDSQNQY
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHH
RKLDENMAVGTIEFTKSGNMAFVQCSDGSEIAVKVENSGISLHKDLVLVEIIGKWRDLKE
HHHHCCCEEEEEEEECCCCEEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCC
GRVVRILKRELKYVVGEFVRKGIFGFVIPIDAKINTDFYVAPEGIGKAKNGQIVKAKITK
CHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEECCCEEECCCCCCCCCCCCEEEEEEHH
YQSPTKKPEVEIVDVLGDKDDPSIDLPIVIFKHGLPEPGYFPPKVLQEAKELPKKLSENE
CCCCCCCCCEEEEEEECCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCC
INGRKDFRKETIFTIDGDTAKDFDDAVGIKKLDNGNYLLGVHIADVSHYVKSNSALDREA
CCCHHHHHHCEEEEECCCCCCCHHHHCCCEEECCCCEEEEEEEHHHHHHHHCCCCCCHHH
YKRGTSVYLIDTVIPMLPFELSNWICSLVEGEDRLTMSLLMEIDPYGNLVNSKIYNGVIR
HHCCCEEEEHHHHHHHCCHHHHHHHHHHHCCCCHHEEHHHHHCCCCCCHHHHHHHHHHHH
SAKRLTYRKVNELLSDNCSEEVKKEIEFLKPELEMMRELMELLSEKRKERGSIIDIESNE
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCEEEEECCE
VHFEFDEKGYVKDIIPVERGLSEKMIEEFMVLANETVASYFDVQGLPFIYRIHENPDPDV
EEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHH
LLQLRNYLDMLGINVKFPQNIHPKVLQEILEKTKNHPLSKNIQMMLVRSMKRALYSEENV
HHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCC
GHFGLASSSYTHFTSPIRRYPDLVVHRLLKEFIKYKGTLSKKEIKKYSEMLPEIAKNSSE
CCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHH
MERVADQAEWDLIDMKKVEYISRHIGEVFWVYITGVTRFGLFVEIPQKMISGLIHISELS
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHEECC
DDYYIYDERDNTLKGERTGNVYRIGDKLQAKVVRADKIGTEVDFIPYTEDDFEKLKREHP
CCEEEEECCCCCCCCCCCCCEEEECCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCC
HAKIKVNKKNKKKRKKS
CCEEEECCCHHHHCCCC
>Mature Secondary Structure
MNEDNLEKQILEIIDKNPTIQKELYESLNALEKSEKAQIRKILNKLLSEGKIIKDSQNQY
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHH
RKLDENMAVGTIEFTKSGNMAFVQCSDGSEIAVKVENSGISLHKDLVLVEIIGKWRDLKE
HHHHCCCEEEEEEEECCCCEEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCC
GRVVRILKRELKYVVGEFVRKGIFGFVIPIDAKINTDFYVAPEGIGKAKNGQIVKAKITK
CHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEECCCEEECCCCCCCCCCCCEEEEEEHH
YQSPTKKPEVEIVDVLGDKDDPSIDLPIVIFKHGLPEPGYFPPKVLQEAKELPKKLSENE
CCCCCCCCCEEEEEEECCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCC
INGRKDFRKETIFTIDGDTAKDFDDAVGIKKLDNGNYLLGVHIADVSHYVKSNSALDREA
CCCHHHHHHCEEEEECCCCCCCHHHHCCCEEECCCCEEEEEEEHHHHHHHHCCCCCCHHH
YKRGTSVYLIDTVIPMLPFELSNWICSLVEGEDRLTMSLLMEIDPYGNLVNSKIYNGVIR
HHCCCEEEEHHHHHHHCCHHHHHHHHHHHCCCCHHEEHHHHHCCCCCCHHHHHHHHHHHH
SAKRLTYRKVNELLSDNCSEEVKKEIEFLKPELEMMRELMELLSEKRKERGSIIDIESNE
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCEEEEECCE
VHFEFDEKGYVKDIIPVERGLSEKMIEEFMVLANETVASYFDVQGLPFIYRIHENPDPDV
EEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHH
LLQLRNYLDMLGINVKFPQNIHPKVLQEILEKTKNHPLSKNIQMMLVRSMKRALYSEENV
HHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCC
GHFGLASSSYTHFTSPIRRYPDLVVHRLLKEFIKYKGTLSKKEIKKYSEMLPEIAKNSSE
CCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHH
MERVADQAEWDLIDMKKVEYISRHIGEVFWVYITGVTRFGLFVEIPQKMISGLIHISELS
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHEECC
DDYYIYDERDNTLKGERTGNVYRIGDKLQAKVVRADKIGTEVDFIPYTEDDFEKLKREHP
CCEEEEECCCCCCCCCCCCCEEEECCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCC
HAKIKVNKKNKKKRKKS
CCEEEECCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]