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The map label for this gene is dnaC [H]

Identifier: 160902436

GI number: 160902436

Start: 1031299

End: 1032669

Strand: Direct

Name: dnaC [H]

Synonym: Pmob_0972

Alternate gene names: 160902436

Gene position: 1031299-1032669 (Clockwise)

Preceding gene: 160902435

Following gene: 160902437

Centisome position: 47.54

GC content: 37.42

Gene sequence:

>1371_bases
ATGGAACTTACTTCTTTTACCCCTCCTAATAGTAAAGAAGCTGAAGAGTCGGTCATAGGTAGCATCTTTTTAGACCCTTC
CATACTTCCTGACGTAATCGAAGAGGTAAGATGGGAAGACTTCTACTACGAAAATAATAAAACAATATTTAAAGTTATGG
AAGAACTTTTCGACAAAGGGGAACCTGTTGATACCGTATCCGTTATTGAAAAATTAAGAGAATCTAACCTTTTACAGAAA
ATCGGTGGAGAAGATACAATAATTTATTTAGCTCAGGTTGTTCCAACAACGGCTAATGTGATGTATTATACCCAAATTGT
CAAAGAGAAAGCCCTTTTAAGAGCTTTAATAAACGCATCTTCCGAGATAGTTGATGCCGTAAGAAATATTGGAGATGCCC
AAGAAGTTTTAGAGTATGCCGAAAAGAGAATATTTTCTATAGCCGAAGCCCGTGCCACCAGAACGTATGATCTTTTATCC
AACGTAATGCATGATGTTTTTGAACAGATAGAAGAATTGAAAAATAGGGCTCAAAAAGGTGAGGGAAATCTTGTTACTGG
GGTTTCTACTGGATTCAAACCTTTGGACAGGATGACTTCAGGATTTCATAGATCTGAGTTAATTATCATCGCCGCTAGAC
CATCAATGGGTAAAACCTCTTTTGCCGCAAATATTGCAACCAACATGGCTTTACAGGCAAATATTGCCGTGGCAATCTTT
AGTTTGGAAATGTCGAAAGAACAGTTAGCTAACAGGATTTTATGTTCTGAAGCAAAAGTAGACTTACACAAGGTTAGAAC
TGGACAAATCTCTGACGAAGAGTGGGAAAAATTAGTTCAAAAAGCAGGAGAATTATCAAAGTCAAGGCTTATTTTTGACG
ACGAACCAGATTTATCCCCTAGACTCCTGAGGGCTAAAGCACGGAGAATGAAAAGAGAATACGGCATTGAAGTAATCTTT
ATCGATTACTTACAATTGATGACTTCTAGATCTAAAGGTTATGAGAGCAGACAACAAGAAATAACAGAGATATCAAGATC
CTTGAAATTGCTCGCTAGAGAGTTAAATATCACTGTCGTTGCTTTATCTCAACTTTCTCGTGCAGTTGAGCAAAGAGAAG
ATAAAAGGCCTCGATTAAGTGATCTCAGAGAATCAGGAGCAATTGAGCAGGATGCCGACCTCGTTATGTTTTTGTACAGA
GATTCATATTACAAAAGGAAAAAAGATGAGCCAGGAAAAGATACTTTAAATGATGAACATGAAGCAGAACTTATTGTAGG
TAAGCAAAGAAACGGGCCCGTTGGAACCATAAAACTAACTTTCAATCCTAAACTTGCAACTTTTTACACCTCTGATAGAG
GATATCAGTAA

Upstream 100 bases:

>100_bases
AAAAATGGACAAAAATGGACTGTTAGGCCTTTTAATAAGTATTGGAATTTTTGCCTTATCTTATTTTTTGAGCTTATTAG
TTTGATCGAGGTGTATGCAA

Downstream 100 bases:

>100_bases
GTTTAGAAACAAGATTTTGATTTAAAAGGGTTACAGGGGTGCTGAAATAAGTTTTAGCTTTTTTAAAAAGTATAATTACA
TTGAAAGGGGGTAAAATATG

Product: replicative DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MELTSFTPPNSKEAEESVIGSIFLDPSILPDVIEEVRWEDFYYENNKTIFKVMEELFDKGEPVDTVSVIEKLRESNLLQK
IGGEDTIIYLAQVVPTTANVMYYTQIVKEKALLRALINASSEIVDAVRNIGDAQEVLEYAEKRIFSIAEARATRTYDLLS
NVMHDVFEQIEELKNRAQKGEGNLVTGVSTGFKPLDRMTSGFHRSELIIIAARPSMGKTSFAANIATNMALQANIAVAIF
SLEMSKEQLANRILCSEAKVDLHKVRTGQISDEEWEKLVQKAGELSKSRLIFDDEPDLSPRLLRAKARRMKREYGIEVIF
IDYLQLMTSRSKGYESRQQEITEISRSLKLLARELNITVVALSQLSRAVEQREDKRPRLSDLRESGAIEQDADLVMFLYR
DSYYKRKKDEPGKDTLNDEHEAELIVGKQRNGPVGTIKLTFNPKLATFYTSDRGYQ

Sequences:

>Translated_456_residues
MELTSFTPPNSKEAEESVIGSIFLDPSILPDVIEEVRWEDFYYENNKTIFKVMEELFDKGEPVDTVSVIEKLRESNLLQK
IGGEDTIIYLAQVVPTTANVMYYTQIVKEKALLRALINASSEIVDAVRNIGDAQEVLEYAEKRIFSIAEARATRTYDLLS
NVMHDVFEQIEELKNRAQKGEGNLVTGVSTGFKPLDRMTSGFHRSELIIIAARPSMGKTSFAANIATNMALQANIAVAIF
SLEMSKEQLANRILCSEAKVDLHKVRTGQISDEEWEKLVQKAGELSKSRLIFDDEPDLSPRLLRAKARRMKREYGIEVIF
IDYLQLMTSRSKGYESRQQEITEISRSLKLLARELNITVVALSQLSRAVEQREDKRPRLSDLRESGAIEQDADLVMFLYR
DSYYKRKKDEPGKDTLNDEHEAELIVGKQRNGPVGTIKLTFNPKLATFYTSDRGYQ
>Mature_456_residues
MELTSFTPPNSKEAEESVIGSIFLDPSILPDVIEEVRWEDFYYENNKTIFKVMEELFDKGEPVDTVSVIEKLRESNLLQK
IGGEDTIIYLAQVVPTTANVMYYTQIVKEKALLRALINASSEIVDAVRNIGDAQEVLEYAEKRIFSIAEARATRTYDLLS
NVMHDVFEQIEELKNRAQKGEGNLVTGVSTGFKPLDRMTSGFHRSELIIIAARPSMGKTSFAANIATNMALQANIAVAIF
SLEMSKEQLANRILCSEAKVDLHKVRTGQISDEEWEKLVQKAGELSKSRLIFDDEPDLSPRLLRAKARRMKREYGIEVIF
IDYLQLMTSRSKGYESRQQEITEISRSLKLLARELNITVVALSQLSRAVEQREDKRPRLSDLRESGAIEQDADLVMFLYR
DSYYKRKKDEPGKDTLNDEHEAELIVGKQRNGPVGTIKLTFNPKLATFYTSDRGYQ

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=447, Percent_Identity=44.9664429530201, Blast_Score=359, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 51857; Mature: 51857

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELTSFTPPNSKEAEESVIGSIFLDPSILPDVIEEVRWEDFYYENNKTIFKVMEELFDKG
CCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCHHHEEEECCCHHHHHHHHHHHCC
EPVDTVSVIEKLRESNLLQKIGGEDTIIYLAQVVPTTANVMYYTQIVKEKALLRALINAS
CCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHCCH
SEIVDAVRNIGDAQEVLEYAEKRIFSIAEARATRTYDLLSNVMHDVFEQIEELKNRAQKG
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EGNLVTGVSTGFKPLDRMTSGFHRSELIIIAARPSMGKTSFAANIATNMALQANIAVAIF
CCCEEEECCCCCHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHEEEECEEEEEE
SLEMSKEQLANRILCSEAKVDLHKVRTGQISDEEWEKLVQKAGELSKSRLIFDDEPDLSP
EHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCHHHCCEEECCCCCCCH
RLLRAKARRMKREYGIEVIFIDYLQLMTSRSKGYESRQQEITEISRSLKLLARELNITVV
HHHHHHHHHHHHHHCCEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCHHEE
ALSQLSRAVEQREDKRPRLSDLRESGAIEQDADLVMFLYRDSYYKRKKDEPGKDTLNDEH
HHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCEEEEEHHHHHHHHCCCCCCCCCCCCCC
EAELIVGKQRNGPVGTIKLTFNPKLATFYTSDRGYQ
CCEEEEECCCCCCEEEEEEEECCCEEEEEECCCCCC
>Mature Secondary Structure
MELTSFTPPNSKEAEESVIGSIFLDPSILPDVIEEVRWEDFYYENNKTIFKVMEELFDKG
CCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCHHHEEEECCCHHHHHHHHHHHCC
EPVDTVSVIEKLRESNLLQKIGGEDTIIYLAQVVPTTANVMYYTQIVKEKALLRALINAS
CCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHCCH
SEIVDAVRNIGDAQEVLEYAEKRIFSIAEARATRTYDLLSNVMHDVFEQIEELKNRAQKG
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EGNLVTGVSTGFKPLDRMTSGFHRSELIIIAARPSMGKTSFAANIATNMALQANIAVAIF
CCCEEEECCCCCHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHEEEECEEEEEE
SLEMSKEQLANRILCSEAKVDLHKVRTGQISDEEWEKLVQKAGELSKSRLIFDDEPDLSP
EHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCHHHCCEEECCCCCCCH
RLLRAKARRMKREYGIEVIFIDYLQLMTSRSKGYESRQQEITEISRSLKLLARELNITVV
HHHHHHHHHHHHHHCCEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCHHEE
ALSQLSRAVEQREDKRPRLSDLRESGAIEQDADLVMFLYRDSYYKRKKDEPGKDTLNDEH
HHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCEEEEEHHHHHHHHCCCCCCCCCCCCCC
EAELIVGKQRNGPVGTIKLTFNPKLATFYTSDRGYQ
CCEEEEECCCCCCEEEEEEEECCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]