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The map label for this gene is (rmlA1 [H]

Identifier: 160902403

GI number: 160902403

Start: 992379

End: 993251

Strand: Direct

Name: (rmlA1 [H]

Synonym: Pmob_0938

Alternate gene names: 160902403

Gene position: 992379-993251 (Clockwise)

Preceding gene: 160902402

Following gene: 160902404

Centisome position: 45.74

GC content: 33.56

Gene sequence:

>873_bases
GTGAAAGGCATAATCCTTGCAGGGGGAAATGGCACAAGACTTTACCCTATCACTAAAGGGCTAAGTAAACAACTTCTTCC
GATATACGATAAACCAATGATCTACTATCCACTATCAACGATAATGTTGGCAGGGATAAGAGAAATTTTAATAATTTCTA
ATCCAGCATATATTGATATGTACAAAAGACTATTAAACGATGGAAGTCATTTAGGGCTAAAGATAGAATACAAAATTCAA
GAAAAACCAAGAGGGCTAGCCGACGCTTTCATTGTTGGCGAAGATTTTGTTGGTGAAGATAGTGCTTGTTTAATCCTTGG
AGATAATGTTTTTTATGGGCAAGACTTTGTTCCAAAATTAAAAAAAGCCGCAAAGTTAGAAAAAGGTGCTATCATTTTTG
GATATTATGTAAATAATCCAACAGAATTTGGAGTTGTAGAATTTGATGAAAATAACAAAGCGGTTAGTTTAGAAGAAAAA
CCTTCGAATCCAAAGTCAAAGTACGCAGTACCTGGATTATATTTTTATGATAACACTGTAGTAGAAAAAGCAAAAAATCT
CCAACCTTCAGATAGAGGAGAGCTAGAAATAACCGATTTGAATAGAATATATTTAGAAGAAAATGAATTGAATGTTGAAG
TCTTAGGAAGAGGTATAGCATGGTTAGACACAGGTACTTACGATGGACTTGCAAATGCCGCTGACTTTGTTAGAACCATT
CAAAAAAGAACTGGTTTATACATCGCTTGTTTGGAAGAAATAGCCTACAGGAACAAATGGATAACAAAAGAAGAATTGAT
TAAATTGGGTAAAGAATATGAAAAGACTGAATATGGTCAATACATTCTTAGATTTGCGAGTGATATAAATTGA

Upstream 100 bases:

>100_bases
TCGGAAAGAATTTTAACCTTGCCTTTATATGCTGATTTAGAATTATCAGATGTAGATCGAATATGTGATATTATAAGAAA
TATTTGAATGAGGTGATATT

Downstream 100 bases:

>100_bases
GTATCTTAGTAACAGGGGTAGCTGGATTCATAGGAAGTAACTTCGTATACTACTACTTAAGAAAACACAAAGACAAAAAG
ATAATAGGTTTAGACAAACT

Product: glucose-1-phosphate thymidylyltransferase

Products: NA

Alternate protein names: dTDP-glucose pyrophosphorylase; dTDP-glucose synthase [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MKGIILAGGNGTRLYPITKGLSKQLLPIYDKPMIYYPLSTIMLAGIREILIISNPAYIDMYKRLLNDGSHLGLKIEYKIQ
EKPRGLADAFIVGEDFVGEDSACLILGDNVFYGQDFVPKLKKAAKLEKGAIIFGYYVNNPTEFGVVEFDENNKAVSLEEK
PSNPKSKYAVPGLYFYDNTVVEKAKNLQPSDRGELEITDLNRIYLEENELNVEVLGRGIAWLDTGTYDGLANAADFVRTI
QKRTGLYIACLEEIAYRNKWITKEELIKLGKEYEKTEYGQYILRFASDIN

Sequences:

>Translated_290_residues
MKGIILAGGNGTRLYPITKGLSKQLLPIYDKPMIYYPLSTIMLAGIREILIISNPAYIDMYKRLLNDGSHLGLKIEYKIQ
EKPRGLADAFIVGEDFVGEDSACLILGDNVFYGQDFVPKLKKAAKLEKGAIIFGYYVNNPTEFGVVEFDENNKAVSLEEK
PSNPKSKYAVPGLYFYDNTVVEKAKNLQPSDRGELEITDLNRIYLEENELNVEVLGRGIAWLDTGTYDGLANAADFVRTI
QKRTGLYIACLEEIAYRNKWITKEELIKLGKEYEKTEYGQYILRFASDIN
>Mature_290_residues
MKGIILAGGNGTRLYPITKGLSKQLLPIYDKPMIYYPLSTIMLAGIREILIISNPAYIDMYKRLLNDGSHLGLKIEYKIQ
EKPRGLADAFIVGEDFVGEDSACLILGDNVFYGQDFVPKLKKAAKLEKGAIIFGYYVNNPTEFGVVEFDENNKAVSLEEK
PSNPKSKYAVPGLYFYDNTVVEKAKNLQPSDRGELEITDLNRIYLEENELNVEVLGRGIAWLDTGTYDGLANAADFVRTI
QKRTGLYIACLEEIAYRNKWITKEELIKLGKEYEKTEYGQYILRFASDIN

Specific function: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis [H]

COG id: COG1209

COG function: function code M; dTDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-1-phosphate thymidylyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790224, Length=283, Percent_Identity=61.4840989399293, Blast_Score=370, Evalue=1e-104,
Organism=Escherichia coli, GI1788351, Length=290, Percent_Identity=60.6896551724138, Blast_Score=362, Evalue=1e-101,
Organism=Escherichia coli, GI1788355, Length=237, Percent_Identity=23.6286919831224, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI133931050, Length=191, Percent_Identity=24.0837696335079, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320148, Length=256, Percent_Identity=26.5625, Blast_Score=65, Evalue=9e-12,
Organism=Drosophila melanogaster, GI21355443, Length=227, Percent_Identity=24.6696035242291, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24644084, Length=227, Percent_Identity=24.6696035242291, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005907
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.24 [H]

Molecular weight: Translated: 32785; Mature: 32785

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGIILAGGNGTRLYPITKGLSKQLLPIYDKPMIYYPLSTIMLAGIREILIISNPAYIDM
CCEEEEECCCCCEEEEECCCCCCCCCCCCCCCEEEECHHHHHHHCCCEEEEECCCHHHHH
YKRLLNDGSHLGLKIEYKIQEKPRGLADAFIVGEDFVGEDSACLILGDNVFYGQDFVPKL
HHHHHCCCCEEEEEEEEEECCCCCCCHHEEEECCCCCCCCCEEEEEECCEEECCCHHHHH
KKAAKLEKGAIIFGYYVNNPTEFGVVEFDENNKAVSLEEKPSNPKSKYAVPGLYFYDNTV
HHHHHCCCCCEEEEEEECCCCEEEEEEECCCCCEEEECCCCCCCCCCCCCCEEEEECCHH
VEKAKNLQPSDRGELEITDLNRIYLEENELNVEVLGRGIAWLDTGTYDGLANAADFVRTI
HHHHHCCCCCCCCCEEEEECEEEEEECCCCEEEEEECCEEEEECCCCCCHHHHHHHHHHH
QKRTGLYIACLEEIAYRNKWITKEELIKLGKEYEKTEYGQYILRFASDIN
HHHCCEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKGIILAGGNGTRLYPITKGLSKQLLPIYDKPMIYYPLSTIMLAGIREILIISNPAYIDM
CCEEEEECCCCCEEEEECCCCCCCCCCCCCCCEEEECHHHHHHHCCCEEEEECCCHHHHH
YKRLLNDGSHLGLKIEYKIQEKPRGLADAFIVGEDFVGEDSACLILGDNVFYGQDFVPKL
HHHHHCCCCEEEEEEEEEECCCCCCCHHEEEECCCCCCCCCEEEEEECCEEECCCHHHHH
KKAAKLEKGAIIFGYYVNNPTEFGVVEFDENNKAVSLEEKPSNPKSKYAVPGLYFYDNTV
HHHHHCCCCCEEEEEEECCCCEEEEEEECCCCCEEEECCCCCCCCCCCCCCEEEEECCHH
VEKAKNLQPSDRGELEITDLNRIYLEENELNVEVLGRGIAWLDTGTYDGLANAADFVRTI
HHHHHCCCCCCCCCEEEEECEEEEEECCCCEEEEEECCEEEEECCCCCCHHHHHHHHHHH
QKRTGLYIACLEEIAYRNKWITKEELIKLGKEYEKTEYGQYILRFASDIN
HHHCCEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]