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The map label for this gene is pgsA [H]

Identifier: 160901570

GI number: 160901570

Start: 77232

End: 77741

Strand: Direct

Name: pgsA [H]

Synonym: Pmob_0079

Alternate gene names: 160901570

Gene position: 77232-77741 (Clockwise)

Preceding gene: 160901569

Following gene: 160901571

Centisome position: 3.56

GC content: 34.51

Gene sequence:

>510_bases
ATGAACATACCAAATTTATTGAGTTTTTCTAGGATAATATTAGCCATTCCAATATTCATCCTAACTGTCTTTGGAGAACA
GTTTTATACCGCAGCCTTGGTTTTGTTTATTATAGCTTCCTTAACCGATTGGTTAGACGGTTATGTCGCCAGAAAGACTG
GTCAGGTTACCGATATCGGCAAATTTTTTGATCAAATATCTGACAAAATACTTATAAACTCGGTTTTTATTGCGATGTTG
GGTGTAGGAATTTTGCCTGCCTGGTTTGTTGCAATAATTGTATCAAGAGACACCTTTGTCAGCGGTTTAAGGATGGCAGC
TGCAAATAAAAACATCGTTGTCCCTGCTGATAAGTTTGGTAAACTAAAAACCGTCTTAGAAATCGCTTTAATTATTGTAA
TATATTTGATGCTATGGAATTTTCTAATTACTACTTTGATCTATTTGACCGTTATAATCAGTCTATTATCGGGAGTTAAT
TATACTGTCAAAACCGCCAAACAATTCTAA

Upstream 100 bases:

>100_bases
ATATAAAAAATTTTGGTGACAAAGAACTAACTTTTGGGAATTTTGTCAAGGTGACAATTACTGGTTCATACGAATATGAT
CTGGAAGGAGAAATAGTTGA

Downstream 100 bases:

>100_bases
AAAAGAAAGGAGTCCTAGTATATGACACAGCTAAAAAATGTAAATAACCACAATACCGACAAATTAAGATCCTTCATCGC
CATCGAAACTAATGAAAAAT

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MNIPNLLSFSRIILAIPIFILTVFGEQFYTAALVLFIIASLTDWLDGYVARKTGQVTDIGKFFDQISDKILINSVFIAML
GVGILPAWFVAIIVSRDTFVSGLRMAAANKNIVVPADKFGKLKTVLEIALIIVIYLMLWNFLITTLIYLTVIISLLSGVN
YTVKTAKQF

Sequences:

>Translated_169_residues
MNIPNLLSFSRIILAIPIFILTVFGEQFYTAALVLFIIASLTDWLDGYVARKTGQVTDIGKFFDQISDKILINSVFIAML
GVGILPAWFVAIIVSRDTFVSGLRMAAANKNIVVPADKFGKLKTVLEIALIIVIYLMLWNFLITTLIYLTVIISLLSGVN
YTVKTAKQF
>Mature_169_residues
MNIPNLLSFSRIILAIPIFILTVFGEQFYTAALVLFIIASLTDWLDGYVARKTGQVTDIGKFFDQISDKILINSVFIAML
GVGILPAWFVAIIVSRDTFVSGLRMAAANKNIVVPADKFGKLKTVLEIALIIVIYLMLWNFLITTLIYLTVIISLLSGVN
YTVKTAKQF

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=175, Percent_Identity=32.5714285714286, Blast_Score=77, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI71984834, Length=96, Percent_Identity=38.5416666666667, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71984838, Length=96, Percent_Identity=38.5416666666667, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320059, Length=102, Percent_Identity=41.1764705882353, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24650130, Length=103, Percent_Identity=37.8640776699029, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24650126, Length=103, Percent_Identity=37.8640776699029, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24650128, Length=103, Percent_Identity=37.8640776699029, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 18783; Mature: 18783

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIPNLLSFSRIILAIPIFILTVFGEQFYTAALVLFIIASLTDWLDGYVARKTGQVTDIG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
KFFDQISDKILINSVFIAMLGVGILPAWFVAIIVSRDTFVSGLRMAAANKNIVVPADKFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHH
KLKTVLEIALIIVIYLMLWNFLITTLIYLTVIISLLSGVNYTVKTAKQF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCC
>Mature Secondary Structure
MNIPNLLSFSRIILAIPIFILTVFGEQFYTAALVLFIIASLTDWLDGYVARKTGQVTDIG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
KFFDQISDKILINSVFIAMLGVGILPAWFVAIIVSRDTFVSGLRMAAANKNIVVPADKFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHH
KLKTVLEIALIIVIYLMLWNFLITTLIYLTVIISLLSGVNYTVKTAKQF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7750561; 9384377 [H]