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The map label for this gene is cyoE1 [H]

Identifier: 160877421

GI number: 160877421

Start: 5101249

End: 5102154

Strand: Direct

Name: cyoE1 [H]

Synonym: Sbal195_4319

Alternate gene names: 160877421

Gene position: 5101249-5102154 (Clockwise)

Preceding gene: 160877420

Following gene: 160877422

Centisome position: 95.4

GC content: 49.78

Gene sequence:

>906_bases
ATGGCAAAACCACTCTCAATCACCAGTAGCCTACCCACGTTCAGCGTGACATGGCGCGCCTATTTTGAAATGACTAAACC
TAAAGTGGTCGCACTTATGCTGCTCACTGTCTTAGTCGGCATGTGTTTGGCCGTGCCCCATGCTGTGCCCGTTCAACCTT
TACTCGCAGGCATGCTGGGCATTGCCATGATGGCGGGTTCGGCGGCAGCGTTGAATCATCTGATCGATCGCCGTATCGAT
GGCTTAATGGCACGCACCTACAATCGCCCACTACCCAAAGGGCGTATTTCGGCAACCCGCGCGTTAATTTTCGCCGCTAG
CTTAGGTAGCCTTGGCTTTATCGTCTTATATTCCTTAGTAAATCCACTCACGGCTTGGCTCACCTTTGCCAGCTTGATTG
GTTATGCCTTGGTTTATACTGCCTATTTGAAGCGCGCGACATCACAAAACATTGTGATTGGCGGCCTTGCGGGAGCCATG
CCACCCTTGCTGGGATGGACGGCAGTGACGAACGAATTTCACGGCCATGCACTGTTGTTAGTGATCATCATCTTTACGTG
GACGCCGCCACATTTTTGGGCTCTGGCCATTCACAGACGCGCCGAATATGCCAAAGTGGATATTCCCATGCTGCCGGTTA
CCCACGGTGTCGAGTTTACTAAAACCTGTATTCTGCTTTACACAGTATTGCTGGCGATTGCTTGCCTATTACCTGTGCTG
GTTGGCATGTGTGGGCCCGTGTATTTTGTCTGCTCGAGTTTACTCAGCACCGGATTTATCTATAAAGCATGGCAACTTAA
ATATCGGGATCATGATGGTTTGGCGATGCAAGTGTTCCGCTTCTCTATCTATCATTTGATGTTGTTATTCATGGCATTAC
TGCTCGACCACTATTTGTGGAACTAG

Upstream 100 bases:

>100_bases
GTATTGCCGTGTCTCACAACGGCGGGGCGGCACTACTGCTGCTGACCTTAGTCGCAATCAACTATTTCTTATGGCGCAAA
GCCTAAGCGAGGGCTCCAAG

Downstream 100 bases:

>100_bases
TGTATGCAACTCGTTTGTCGCGCTAACCTGTCGTTATGGAGCCAATAATGCAGAAAAGAATTTTAGTCATCGCCATATTA
TTGATCGGCCTTGGCGGTCT

Product: protoheme IX farnesyltransferase

Products: NA

Alternate protein names: Heme B farnesyltransferase 1; Heme O synthase 1 [H]

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MAKPLSITSSLPTFSVTWRAYFEMTKPKVVALMLLTVLVGMCLAVPHAVPVQPLLAGMLGIAMMAGSAAALNHLIDRRID
GLMARTYNRPLPKGRISATRALIFAASLGSLGFIVLYSLVNPLTAWLTFASLIGYALVYTAYLKRATSQNIVIGGLAGAM
PPLLGWTAVTNEFHGHALLLVIIIFTWTPPHFWALAIHRRAEYAKVDIPMLPVTHGVEFTKTCILLYTVLLAIACLLPVL
VGMCGPVYFVCSSLLSTGFIYKAWQLKYRDHDGLAMQVFRFSIYHLMLLFMALLLDHYLWN

Sequences:

>Translated_301_residues
MAKPLSITSSLPTFSVTWRAYFEMTKPKVVALMLLTVLVGMCLAVPHAVPVQPLLAGMLGIAMMAGSAAALNHLIDRRID
GLMARTYNRPLPKGRISATRALIFAASLGSLGFIVLYSLVNPLTAWLTFASLIGYALVYTAYLKRATSQNIVIGGLAGAM
PPLLGWTAVTNEFHGHALLLVIIIFTWTPPHFWALAIHRRAEYAKVDIPMLPVTHGVEFTKTCILLYTVLLAIACLLPVL
VGMCGPVYFVCSSLLSTGFIYKAWQLKYRDHDGLAMQVFRFSIYHLMLLFMALLLDHYLWN
>Mature_300_residues
AKPLSITSSLPTFSVTWRAYFEMTKPKVVALMLLTVLVGMCLAVPHAVPVQPLLAGMLGIAMMAGSAAALNHLIDRRIDG
LMARTYNRPLPKGRISATRALIFAASLGSLGFIVLYSLVNPLTAWLTFASLIGYALVYTAYLKRATSQNIVIGGLAGAMP
PLLGWTAVTNEFHGHALLLVIIIFTWTPPHFWALAIHRRAEYAKVDIPMLPVTHGVEFTKTCILLYTVLLAIACLLPVLV
GMCGPVYFVCSSLLSTGFIYKAWQLKYRDHDGLAMQVFRFSIYHLMLLFMALLLDHYLWN

Specific function: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group [H]

COG id: COG0109

COG function: function code O; Polyprenyltransferase (cytochrome oxidase assembly factor)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI17921982, Length=193, Percent_Identity=35.2331606217617, Blast_Score=103, Evalue=1e-22,
Organism=Escherichia coli, GI1786631, Length=280, Percent_Identity=35, Blast_Score=164, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI71998235, Length=195, Percent_Identity=32.8205128205128, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6325085, Length=185, Percent_Identity=35.1351351351351, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI19921064, Length=303, Percent_Identity=28.3828382838284, Blast_Score=123, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006369
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 33227; Mature: 33096

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKPLSITSSLPTFSVTWRAYFEMTKPKVVALMLLTVLVGMCLAVPHAVPVQPLLAGMLG
CCCCCCCCCCCCCEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
IAMMAGSAAALNHLIDRRIDGLMARTYNRPLPKGRISATRALIFAASLGSLGFIVLYSLV
HHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NPLTAWLTFASLIGYALVYTAYLKRATSQNIVIGGLAGAMPPLLGWTAVTNEFHGHALLL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHCCCCHHHHH
VIIIFTWTPPHFWALAIHRRAEYAKVDIPMLPVTHGVEFTKTCILLYTVLLAIACLLPVL
HHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VGMCGPVYFVCSSLLSTGFIYKAWQLKYRDHDGLAMQVFRFSIYHLMLLFMALLLDHYLW
HHHHHHHHHHHHHHHHCCHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
N
C
>Mature Secondary Structure 
AKPLSITSSLPTFSVTWRAYFEMTKPKVVALMLLTVLVGMCLAVPHAVPVQPLLAGMLG
CCCCCCCCCCCCEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
IAMMAGSAAALNHLIDRRIDGLMARTYNRPLPKGRISATRALIFAASLGSLGFIVLYSLV
HHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NPLTAWLTFASLIGYALVYTAYLKRATSQNIVIGGLAGAMPPLLGWTAVTNEFHGHALLL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHCCCCHHHHH
VIIIFTWTPPHFWALAIHRRAEYAKVDIPMLPVTHGVEFTKTCILLYTVLLAIACLLPVL
HHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VGMCGPVYFVCSSLLSTGFIYKAWQLKYRDHDGLAMQVFRFSIYHLMLLFMALLLDHYLW
HHHHHHHHHHHHHHHHCCHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
N
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA