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The map label for this gene is aroE [H]

Identifier: 160873165

GI number: 160873165

Start: 42483

End: 43331

Strand: Direct

Name: aroE [H]

Synonym: Sbal195_0039

Alternate gene names: 160873165

Gene position: 42483-43331 (Clockwise)

Preceding gene: 160873163

Following gene: 160873166

Centisome position: 0.79

GC content: 51.59

Gene sequence:

>849_bases
ATGACAGACAGATACGCAGTGTTTGGCAATCCAATTAGCCACAGTAAATCGCCGTTCATCCATGGACAATTTGCCGCGCC
CACCCAAGAGTCATTAACCTATGAAGCTATTCTTGCTCCGGTCGATGGTTTTGAAGCCTCATTGACGGCGTTTTTCAATG
CGGGCGGCAAGGGCGCCAATGTGACAGTGCCTTTTAAGGAGCAAGCTTTTGCGCTGTGTGACAGTATCAGCCCCGAAGCC
AAACTCGCTGGCGCAGTCAACACCTTAAGTTTATTGGCCGATGGAACTATTCGCGGTGATAACACCGACGGCTTAGGGCT
GGTGGCCGATCTCATCGCTAACTTAGGTAGCTTGCAAGATCAGCGCGTGTTACTCATTGGCGCTGGTGGCGCGGCGCGCG
GTTGTATTCTGCCGTTATTAAATGCGGAGATTGCACAACTGACCATCAGCAATCGCACCCACACTAAGGCGCAGCTTTTG
GTCGATATCTTTACTTCTGTAGATAACGGCGCTTACGCGAGTAAAGTCACCGCCGTAGAAATGAGTGAGCTTGCGGGCGA
GTTCGATATCATTATTAATTCAACCTCTGCTAGCCTTGCGGGCGAGTTGCCACCTTTGCCAGCACATATCATCACCACCC
AAACCGTTTGTTATGACATGATGTATGGCGCCTCGGTCACCGCGTTTAACCAATGGGCACTCTCCCAAGGTGCGGCGAAA
GCCATTGATGGGCTAGGTATGTTAGTCGGACAAGCGGCTAAGAGTTTTACCCTATGGCGAGGTGTTGAGCCCGACACCCA
AGTGGTGTTGACGCTTTTGCGGGACAAACTAATGGCAGAGCCTAAGTAG

Upstream 100 bases:

>100_bases
GTGAAACCTAGCGTGAAATTTAGTTGAGCATAATTCGTCTTGCATGGGCTCAAAAGCGCGGTAGACTGCAAAGCCATTGA
ACCTAAAATTTCATATCGCT

Downstream 100 bases:

>100_bases
GAAGCATGAATCAAAGTATTCTTTTCCCCGATCTGCAATATTGGGACGATGCCCAAGGGCAAATCTGTTTTATGGCGCAA
TCGCAGGGGATGAACATCAA

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MTDRYAVFGNPISHSKSPFIHGQFAAPTQESLTYEAILAPVDGFEASLTAFFNAGGKGANVTVPFKEQAFALCDSISPEA
KLAGAVNTLSLLADGTIRGDNTDGLGLVADLIANLGSLQDQRVLLIGAGGAARGCILPLLNAEIAQLTISNRTHTKAQLL
VDIFTSVDNGAYASKVTAVEMSELAGEFDIIINSTSASLAGELPPLPAHIITTQTVCYDMMYGASVTAFNQWALSQGAAK
AIDGLGMLVGQAAKSFTLWRGVEPDTQVVLTLLRDKLMAEPK

Sequences:

>Translated_282_residues
MTDRYAVFGNPISHSKSPFIHGQFAAPTQESLTYEAILAPVDGFEASLTAFFNAGGKGANVTVPFKEQAFALCDSISPEA
KLAGAVNTLSLLADGTIRGDNTDGLGLVADLIANLGSLQDQRVLLIGAGGAARGCILPLLNAEIAQLTISNRTHTKAQLL
VDIFTSVDNGAYASKVTAVEMSELAGEFDIIINSTSASLAGELPPLPAHIITTQTVCYDMMYGASVTAFNQWALSQGAAK
AIDGLGMLVGQAAKSFTLWRGVEPDTQVVLTLLRDKLMAEPK
>Mature_281_residues
TDRYAVFGNPISHSKSPFIHGQFAAPTQESLTYEAILAPVDGFEASLTAFFNAGGKGANVTVPFKEQAFALCDSISPEAK
LAGAVNTLSLLADGTIRGDNTDGLGLVADLIANLGSLQDQRVLLIGAGGAARGCILPLLNAEIAQLTISNRTHTKAQLLV
DIFTSVDNGAYASKVTAVEMSELAGEFDIIINSTSASLAGELPPLPAHIITTQTVCYDMMYGASVTAFNQWALSQGAAKA
IDGLGMLVGQAAKSFTLWRGVEPDTQVVLTLLRDKLMAEPK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=278, Percent_Identity=50.3597122302158, Blast_Score=266, Evalue=1e-72,
Organism=Escherichia coli, GI1787983, Length=286, Percent_Identity=28.3216783216783, Blast_Score=92, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6320332, Length=279, Percent_Identity=27.5985663082437, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 29546; Mature: 29415

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRYAVFGNPISHSKSPFIHGQFAAPTQESLTYEAILAPVDGFEASLTAFFNAGGKGAN
CCCCEEEECCCCCCCCCCEEEEEECCCCHHCCEEEHEEECCCCCHHHHHHEECCCCCCCE
VTVPFKEQAFALCDSISPEAKLAGAVNTLSLLADGTIRGDNTDGLGLVADLIANLGSLQD
EEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHCCCCC
QRVLLIGAGGAARGCILPLLNAEIAQLTISNRTHTKAQLLVDIFTSVDNGAYASKVTAVE
CEEEEEECCCCCCCHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHEEE
MSELAGEFDIIINSTSASLAGELPPLPAHIITTQTVCYDMMYGASVTAFNQWALSQGAAK
HHHHCCCEEEEEECCCCHHCCCCCCCCHHHHHHHHHHHHHHHCCEEHHHHHHHHHCCHHH
AIDGLGMLVGQAAKSFTLWRGVEPDTQVVLTLLRDKLMAEPK
HHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TDRYAVFGNPISHSKSPFIHGQFAAPTQESLTYEAILAPVDGFEASLTAFFNAGGKGAN
CCCEEEECCCCCCCCCCEEEEEECCCCHHCCEEEHEEECCCCCHHHHHHEECCCCCCCE
VTVPFKEQAFALCDSISPEAKLAGAVNTLSLLADGTIRGDNTDGLGLVADLIANLGSLQD
EEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHCCCCC
QRVLLIGAGGAARGCILPLLNAEIAQLTISNRTHTKAQLLVDIFTSVDNGAYASKVTAVE
CEEEEEECCCCCCCHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHEEE
MSELAGEFDIIINSTSASLAGELPPLPAHIITTQTVCYDMMYGASVTAFNQWALSQGAAK
HHHHCCCEEEEEECCCCHHCCCCCCCCHHHHHHHHHHHHHHHCCEEHHHHHHHHHCCHHH
AIDGLGMLVGQAAKSFTLWRGVEPDTQVVLTLLRDKLMAEPK
HHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA