Click here to switch to the map view.

The map label for this gene is yugH [H]

Identifier: 159901103

GI number: 159901103

Start: 5872986

End: 5874146

Strand: Direct

Name: yugH [H]

Synonym: Haur_4591

Alternate gene names: 159901103

Gene position: 5872986-5874146 (Clockwise)

Preceding gene: 159901102

Following gene: 159901104

Centisome position: 92.54

GC content: 50.39

Gene sequence:

>1161_bases
ATGACGCGCGAACGACTTTCTGCAAGGGTGCAGAGCGTTCCACCTTCAGGGATACGGCGGTTTTTCGATATTGCTGCCAC
AATGGATAATGTGATTTCGCTCGGGATCGGCGAACCAGATTTCGTCACGCCTTACACGATTACCCAAGCTGGGATTCGTT
CATTGCAACAGGGCAAAACTGCCTATACTTCGAATTCTGGGACAATCGAATTACGCCAAGAATTGCAAAAACACCTCAAT
CATTTATATGGACTCAATTATGATCCTGAGAATGAGTTGTTGATTACTGTTGGGGTCAGCGAAGCCTTGCAAAATGCGAT
GCTGGCAACGATCGATCCCGGCGATGAGGTGATTATTCCTGAGCCATGTTTTGTGGCGTATGGCCCAAGTGTAGTGTTTG
CTGGCGGGGTTCCAGTGTATGTCAGCACCTCGGTCGAGCAAGAGTTTCAAGTAACCCGCGAGGCAATCGAGGCCGCGATC
ACGCCGAAAACCAAAGCAATCTTGATTGGCTATCCCAATAATCCAACTGGTGCGGTGATGAGCCGCGAACGCTTGTTGGA
TATCGCTGCCCTAGCTGAGCAATACGATCTCTTAGTATTTTCCGATGAGATTTACGATCGTTTGGTGTATGGCGTTGAAC
ATACCAGCTTTGCCCAATTGCCTGGCATGCGCGATCGTACAATTTTGCTTGGCGGGTTCTCCAAGGCCTATGCCATGACT
GGCTGGCGTTTGGGTTGGTTGGCGGCTAGTGCCGAAATTGCTAATGCTGTGCGCAAAATCCATCAATACGCTATTATGTC
TGCGCCAACCGTAGCCCAATATGCTGGTTTAGCGGCGCTGCAAACTGGCGAAGAAGATGTGCAGCGCATGGTCAGCGAAT
ATGATCGCCGTCGCCAAGTGATTGTGGCTGGATTGCGCCAAATTGGCTTGCCAACTTTCGAGCCACAGGGTGCATTCTAT
GTCTTTCCACAAGTTAGTAGCCTTGGCCTAACCAGCGAAGCCTTTGTCGAAGGCTTGCTCTATCGTGAAAAAGTGGCAGT
TGTGCCAGGCGATGCCTTTGGCCCAAGCGGCGCTGGCTTCGTGCGCATGTGCTACGCTACCAGCATGGATAATATCGAAA
CTGCCTTAGAACGAATTGAGCGCTACGTTCGTTCATTGTAA

Upstream 100 bases:

>100_bases
TCCCCCTGAGTTGCTGCGGCAATTCAGGGGGATGTTTTTTTGCAAAATGACTGTGGTATCATACACCCGCGATCCAAATC
AAGCAGCCAAGGAGGCAGCC

Downstream 100 bases:

>100_bases
ATTTAATGAGGATGCGCCATGAGTTCCGAATCATCTGTTGAATGTACTCGCTGTAAACGACAGCTTAAAGCCGATGAGGT
GCGCATGGCGCAACCGTTGA

Product: class I and II aminotransferase

Products: N-succinyl-2-L-amino-6-oxoheptanedioate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MTRERLSARVQSVPPSGIRRFFDIAATMDNVISLGIGEPDFVTPYTITQAGIRSLQQGKTAYTSNSGTIELRQELQKHLN
HLYGLNYDPENELLITVGVSEALQNAMLATIDPGDEVIIPEPCFVAYGPSVVFAGGVPVYVSTSVEQEFQVTREAIEAAI
TPKTKAILIGYPNNPTGAVMSRERLLDIAALAEQYDLLVFSDEIYDRLVYGVEHTSFAQLPGMRDRTILLGGFSKAYAMT
GWRLGWLAASAEIANAVRKIHQYAIMSAPTVAQYAGLAALQTGEEDVQRMVSEYDRRRQVIVAGLRQIGLPTFEPQGAFY
VFPQVSSLGLTSEAFVEGLLYREKVAVVPGDAFGPSGAGFVRMCYATSMDNIETALERIERYVRSL

Sequences:

>Translated_386_residues
MTRERLSARVQSVPPSGIRRFFDIAATMDNVISLGIGEPDFVTPYTITQAGIRSLQQGKTAYTSNSGTIELRQELQKHLN
HLYGLNYDPENELLITVGVSEALQNAMLATIDPGDEVIIPEPCFVAYGPSVVFAGGVPVYVSTSVEQEFQVTREAIEAAI
TPKTKAILIGYPNNPTGAVMSRERLLDIAALAEQYDLLVFSDEIYDRLVYGVEHTSFAQLPGMRDRTILLGGFSKAYAMT
GWRLGWLAASAEIANAVRKIHQYAIMSAPTVAQYAGLAALQTGEEDVQRMVSEYDRRRQVIVAGLRQIGLPTFEPQGAFY
VFPQVSSLGLTSEAFVEGLLYREKVAVVPGDAFGPSGAGFVRMCYATSMDNIETALERIERYVRSL
>Mature_385_residues
TRERLSARVQSVPPSGIRRFFDIAATMDNVISLGIGEPDFVTPYTITQAGIRSLQQGKTAYTSNSGTIELRQELQKHLNH
LYGLNYDPENELLITVGVSEALQNAMLATIDPGDEVIIPEPCFVAYGPSVVFAGGVPVYVSTSVEQEFQVTREAIEAAIT
PKTKAILIGYPNNPTGAVMSRERLLDIAALAEQYDLLVFSDEIYDRLVYGVEHTSFAQLPGMRDRTILLGGFSKAYAMTG
WRLGWLAASAEIANAVRKIHQYAIMSAPTVAQYAGLAALQTGEEDVQRMVSEYDRRRQVIVAGLRQIGLPTFEPQGAFYV
FPQVSSLGLTSEAFVEGLLYREKVAVVPGDAFGPSGAGFVRMCYATSMDNIETALERIERYVRSL

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=420, Percent_Identity=29.5238095238095, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI169881279, Length=420, Percent_Identity=29.5238095238095, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI56713254, Length=393, Percent_Identity=30.7888040712468, Blast_Score=172, Evalue=4e-43,
Organism=Homo sapiens, GI56713256, Length=393, Percent_Identity=30.7888040712468, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI169881281, Length=302, Percent_Identity=29.4701986754967, Blast_Score=145, Evalue=9e-35,
Organism=Homo sapiens, GI4507369, Length=414, Percent_Identity=25.8454106280193, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI187936925, Length=393, Percent_Identity=24.1730279898219, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI14211921, Length=393, Percent_Identity=24.1730279898219, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI149944424, Length=381, Percent_Identity=23.0971128608924, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI1788722, Length=399, Percent_Identity=31.077694235589, Blast_Score=191, Evalue=6e-50,
Organism=Escherichia coli, GI1786816, Length=363, Percent_Identity=27.8236914600551, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1788627, Length=371, Percent_Identity=29.6495956873315, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1787710, Length=258, Percent_Identity=27.5193798449612, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790797, Length=303, Percent_Identity=25.4125412541254, Blast_Score=83, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17567369, Length=410, Percent_Identity=31.4634146341463, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI71994472, Length=413, Percent_Identity=30.5084745762712, Blast_Score=172, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI71994476, Length=413, Percent_Identity=30.5084745762712, Blast_Score=171, Evalue=6e-43,
Organism=Caenorhabditis elegans, GI17567663, Length=310, Percent_Identity=28.0645161290323, Blast_Score=112, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6322401, Length=321, Percent_Identity=29.2834890965732, Blast_Score=138, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6320317, Length=339, Percent_Identity=25.3687315634218, Blast_Score=76, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6323118, Length=340, Percent_Identity=24.7058823529412, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28573069, Length=417, Percent_Identity=30.4556354916067, Blast_Score=184, Evalue=8e-47,
Organism=Drosophila melanogaster, GI24646114, Length=417, Percent_Identity=30.4556354916067, Blast_Score=184, Evalue=8e-47,
Organism=Drosophila melanogaster, GI28573067, Length=417, Percent_Identity=30.4556354916067, Blast_Score=184, Evalue=8e-47,
Organism=Drosophila melanogaster, GI28573065, Length=417, Percent_Identity=30.4556354916067, Blast_Score=184, Evalue=8e-47,
Organism=Drosophila melanogaster, GI18859735, Length=377, Percent_Identity=25.7294429708223, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24641770, Length=395, Percent_Identity=23.5443037974684, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24641760, Length=395, Percent_Identity=23.5443037974684, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24641768, Length=395, Percent_Identity=23.5443037974684, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24641766, Length=395, Percent_Identity=23.5443037974684, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24641764, Length=395, Percent_Identity=23.5443037974684, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI45551451, Length=395, Percent_Identity=23.5443037974684, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.17

Molecular weight: Translated: 42340; Mature: 42209

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRERLSARVQSVPPSGIRRFFDIAATMDNVISLGIGEPDFVTPYTITQAGIRSLQQGKT
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCC
AYTSNSGTIELRQELQKHLNHLYGLNYDPENELLITVGVSEALQNAMLATIDPGDEVIIP
EEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHCCCEEEEECCCCCEECC
EPCFVAYGPSVVFAGGVPVYVSTSVEQEFQVTREAIEAAITPKTKAILIGYPNNPTGAVM
CCCEEEECCCEEEECCCCEEEECCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHH
SRERLLDIAALAEQYDLLVFSDEIYDRLVYGVEHTSFAQLPGMRDRTILLGGFSKAYAMT
HHHHHHHHHHHHHHHCEEEECHHHHHHHHHCCCCCCHHHCCCCCCCEEEEECCHHHHHHC
GWRLGWLAASAEIANAVRKIHQYAIMSAPTVAQYAGLAALQTGEEDVQRMVSEYDRRRQV
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHH
IVAGLRQIGLPTFEPQGAFYVFPQVSSLGLTSEAFVEGLLYREKVAVVPGDAFGPSGAGF
HHHHHHHHCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHEEEECCCCCCCCCCCCH
VRMCYATSMDNIETALERIERYVRSL
HHHHHHHCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TRERLSARVQSVPPSGIRRFFDIAATMDNVISLGIGEPDFVTPYTITQAGIRSLQQGKT
CHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCC
AYTSNSGTIELRQELQKHLNHLYGLNYDPENELLITVGVSEALQNAMLATIDPGDEVIIP
EEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHCCCEEEEECCCCCEECC
EPCFVAYGPSVVFAGGVPVYVSTSVEQEFQVTREAIEAAITPKTKAILIGYPNNPTGAVM
CCCEEEECCCEEEECCCCEEEECCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHH
SRERLLDIAALAEQYDLLVFSDEIYDRLVYGVEHTSFAQLPGMRDRTILLGGFSKAYAMT
HHHHHHHHHHHHHHHCEEEECHHHHHHHHHCCCCCCHHHCCCCCCCEEEEECCHHHHHHC
GWRLGWLAASAEIANAVRKIHQYAIMSAPTVAQYAGLAALQTGEEDVQRMVSEYDRRRQV
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHH
IVAGLRQIGLPTFEPQGAFYVFPQVSSLGLTSEAFVEGLLYREKVAVVPGDAFGPSGAGF
HHHHHHHHCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHEEEECCCCCCCCCCCCH
VRMCYATSMDNIETALERIERYVRSL
HHHHHHHCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-succinyl-L-2,6-diaminoheptanedioate; 2-oxoglutarate

Specific reaction: N-succinyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate = N-succinyl-2-L-amino-6-oxoheptanedioate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377 [H]