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The map label for this gene is rsbRA [H]

Identifier: 159900934

GI number: 159900934

Start: 5657546

End: 5658361

Strand: Direct

Name: rsbRA [H]

Synonym: Haur_4421

Alternate gene names: 159900934

Gene position: 5657546-5658361 (Clockwise)

Preceding gene: 159900933

Following gene: 159900939

Centisome position: 89.14

GC content: 47.3

Gene sequence:

>816_bases
ATGTCAGATTTAGCAGCTTTTTACACCAAACACTTTGATGAAATTATCGACACTACGATCGAATTAATTCAAGCCAATGT
GGTTGAATATAGCAAAATGGCGCGTGATGAGCTTAAAAAGCGAGCTGTTGCCGCCATCGATGCATTAATTCGCGATTTAC
GTGAGCCAGATATCCATGCCTACCAACAACATATGCGAGCGATAAGCTATGAGCGCTTCCGCCAAAATATTCCATTAAAT
AGCGTTCAACAAGTCTTGCGCAGCATTAATCAAGCGACCTCCAATACATTTCGCAAATACTATGCTGAAGATCCCATCCT
TTTGCTCGAAATGGTCGAACGCCTGCATGAGCTAACCGAAGAAGGTATGATGGGCATGTTCAATGGCTATGAAGATGCCC
AAATCGAAATTATCTCCAACCAAGAATCTGCCTTAGCCGAAGTTTCATCACCAATCGTGCCAGTTTATGGTGGAATTCTG
GTGTTGCCACTGATTGGCTCAGTTGATTCGCGGCGAGCTGGCCAAATTATGGAAGCCCTGCTCGAAGCAATCAACACCTA
TAGCGCCGATGTCGTGATTTTGGATATTACGGGTGTTCCGGTGATCGATACTGGCGTTGCCAATTATCTCCTCCAAGCTG
CTCGTGCTGCACGTTTGCTCGGCTCGACCGTGGTGCTGGTGGGGATTGGCGCTGAAATTGCCCAAACGATTGTTCAATTG
GGCATCGATTTGACTGGGATTGTTACCCGCGCCAACCTGCAAGCCGGAGTTGAATATGCGCTCGAATTGCAAGGCCTAGC
GATTCGCCCGCGCTAA

Upstream 100 bases:

>100_bases
GCTGTTAAATCAGCATAGTTTTAGAGACTCGGCAGATCGCAGTAGGTTGGCATTTTTATCGCAATCAAAAAAACCTAAGG
TTTTAGGAGGGCTCGCAACT

Downstream 100 bases:

>100_bases
ACATTAATTGCCTGAGCCACGTCATTTTTTGGTTTGGCGTGGCCTAGCCTTTGGCGATAATTTGGCCGACCGCAGCTTGC
AGGGTTGCGGCGGTCGCGAC

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MSDLAAFYTKHFDEIIDTTIELIQANVVEYSKMARDELKKRAVAAIDALIRDLREPDIHAYQQHMRAISYERFRQNIPLN
SVQQVLRSINQATSNTFRKYYAEDPILLLEMVERLHELTEEGMMGMFNGYEDAQIEIISNQESALAEVSSPIVPVYGGIL
VLPLIGSVDSRRAGQIMEALLEAINTYSADVVILDITGVPVIDTGVANYLLQAARAARLLGSTVVLVGIGAEIAQTIVQL
GIDLTGIVTRANLQAGVEYALELQGLAIRPR

Sequences:

>Translated_271_residues
MSDLAAFYTKHFDEIIDTTIELIQANVVEYSKMARDELKKRAVAAIDALIRDLREPDIHAYQQHMRAISYERFRQNIPLN
SVQQVLRSINQATSNTFRKYYAEDPILLLEMVERLHELTEEGMMGMFNGYEDAQIEIISNQESALAEVSSPIVPVYGGIL
VLPLIGSVDSRRAGQIMEALLEAINTYSADVVILDITGVPVIDTGVANYLLQAARAARLLGSTVVLVGIGAEIAQTIVQL
GIDLTGIVTRANLQAGVEYALELQGLAIRPR
>Mature_270_residues
SDLAAFYTKHFDEIIDTTIELIQANVVEYSKMARDELKKRAVAAIDALIRDLREPDIHAYQQHMRAISYERFRQNIPLNS
VQQVLRSINQATSNTFRKYYAEDPILLLEMVERLHELTEEGMMGMFNGYEDAQIEIISNQESALAEVSSPIVPVYGGILV
LPLIGSVDSRRAGQIMEALLEAINTYSADVVILDITGVPVIDTGVANYLLQAARAARLLGSTVVLVGIGAEIAQTIVQLG
IDLTGIVTRANLQAGVEYALELQGLAIRPR

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 29929; Mature: 29798

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLAAFYTKHFDEIIDTTIELIQANVVEYSKMARDELKKRAVAAIDALIRDLREPDIHA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
YQQHMRAISYERFRQNIPLNSVQQVLRSINQATSNTFRKYYAEDPILLLEMVERLHELTE
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
EGMMGMFNGYEDAQIEIISNQESALAEVSSPIVPVYGGILVLPLIGSVDSRRAGQIMEAL
HCCHHHCCCCCCCEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LEAINTYSADVVILDITGVPVIDTGVANYLLQAARAARLLGSTVVLVGIGAEIAQTIVQL
HHHHHCCCCCEEEEEECCCCEEHHHHHHHHHHHHHHHHHHCCHHHEEECCHHHHHHHHHH
GIDLTGIVTRANLQAGVEYALELQGLAIRPR
CCCHHHHHHHHHHHHHHHHHHHCCCEECCCC
>Mature Secondary Structure 
SDLAAFYTKHFDEIIDTTIELIQANVVEYSKMARDELKKRAVAAIDALIRDLREPDIHA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
YQQHMRAISYERFRQNIPLNSVQQVLRSINQATSNTFRKYYAEDPILLLEMVERLHELTE
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
EGMMGMFNGYEDAQIEIISNQESALAEVSSPIVPVYGGILVLPLIGSVDSRRAGQIMEAL
HCCHHHCCCCCCCEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LEAINTYSADVVILDITGVPVIDTGVANYLLQAARAARLLGSTVVLVGIGAEIAQTIVQL
HHHHHCCCCCEEEEEECCCCEEHHHHHHHHHHHHHHHHHHCCHHHEEECCHHHHHHHHHH
GIDLTGIVTRANLQAGVEYALELQGLAIRPR
CCCHHHHHHHHHHHHHHHHHHHCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]