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The map label for this gene is rsbRA [H]

Identifier: 159900933

GI number: 159900933

Start: 5656619

End: 5657434

Strand: Direct

Name: rsbRA [H]

Synonym: Haur_4420

Alternate gene names: 159900933

Gene position: 5656619-5657434 (Clockwise)

Preceding gene: 159900932

Following gene: 159900934

Centisome position: 89.13

GC content: 48.04

Gene sequence:

>816_bases
ATGACCAACTATTACGAAATGTTCAAGCAGCACGAAGAATCGATCGTCGAAACCATTATTACTACCTTGCAAACCCAAAT
TCCTACCTACGGCAAAATATCACGCGATGATGTTCGCAAACGGGTCATCGCTGGGCTTGATCCATATGCCCGCGATTTGG
ATACAGAGCATCCCAAGGCTTTTCCTGATTATTGGCGCGAAACGAGCTACTTACGGGCGCAACAAGGTATTCCTATTGGC
GATTTCTTGCAGGTTTTGCTCCTTTCCACCGATATTATGATTCAGGGTTTGCGCCAAGCCTACCCCGATAGTACCGCTGA
TCAAATTAATGTGATTGAAAAAGGCCATCAAATTACGACCGCTGCGATTGCTGCTGTCTACGAAGGCTTTCAACAACACA
AAGATGAAATTATCTCATCACAAACCTACGCACTGGCCGAAGTTTCATCGCCAATCGTGCCAGTCTATGAAGGCGTTTTG
GTCTTGCCCTTGATTGGCTCAATCGATTCGATGCGGGCAGGCCAAATTATGGAATCGCTGCTTGAATCAATCAACACCTA
TAGCGCAGATGTCGTCATTTTGGATATTACTGGTGTTCCAGTGATCGACACGGGCGTTGCCAATTATTTGTTGCAATCCG
CTCGCGCCGCGCGTTTGCTTGGTTCAACCGTGGTACTGGTCGGGATTGGCGCTGAAATTGCCCAAACGATTGTCCAATTA
GGCATCGATCTTACGGGCATCGTCACCCGCGCCAACTTACAATCGGGCATCGAATACGCCCTAGATTTACAAGGCTTGGC
GATTCGCCCCCGTTAA

Upstream 100 bases:

>100_bases
CAGACAACGGAAGGGTCGTAGAGAAACCCTTCCGTTGGCCAACCCAAGAAGCGAGATAGCTTGGCAATTCGGAAACGTTG
CCAACATTCAAGGAGCCTGC

Downstream 100 bases:

>100_bases
TTAGGCTCAACGCTGTTAAATCAGCATAGTTTTAGAGACTCGGCAGATCGCAGTAGGTTGGCATTTTTATCGCAATCAAA
AAAACCTAAGGTTTTAGGAG

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MTNYYEMFKQHEESIVETIITTLQTQIPTYGKISRDDVRKRVIAGLDPYARDLDTEHPKAFPDYWRETSYLRAQQGIPIG
DFLQVLLLSTDIMIQGLRQAYPDSTADQINVIEKGHQITTAAIAAVYEGFQQHKDEIISSQTYALAEVSSPIVPVYEGVL
VLPLIGSIDSMRAGQIMESLLESINTYSADVVILDITGVPVIDTGVANYLLQSARAARLLGSTVVLVGIGAEIAQTIVQL
GIDLTGIVTRANLQSGIEYALDLQGLAIRPR

Sequences:

>Translated_271_residues
MTNYYEMFKQHEESIVETIITTLQTQIPTYGKISRDDVRKRVIAGLDPYARDLDTEHPKAFPDYWRETSYLRAQQGIPIG
DFLQVLLLSTDIMIQGLRQAYPDSTADQINVIEKGHQITTAAIAAVYEGFQQHKDEIISSQTYALAEVSSPIVPVYEGVL
VLPLIGSIDSMRAGQIMESLLESINTYSADVVILDITGVPVIDTGVANYLLQSARAARLLGSTVVLVGIGAEIAQTIVQL
GIDLTGIVTRANLQSGIEYALDLQGLAIRPR
>Mature_270_residues
TNYYEMFKQHEESIVETIITTLQTQIPTYGKISRDDVRKRVIAGLDPYARDLDTEHPKAFPDYWRETSYLRAQQGIPIGD
FLQVLLLSTDIMIQGLRQAYPDSTADQINVIEKGHQITTAAIAAVYEGFQQHKDEIISSQTYALAEVSSPIVPVYEGVLV
LPLIGSIDSMRAGQIMESLLESINTYSADVVILDITGVPVIDTGVANYLLQSARAARLLGSTVVLVGIGAEIAQTIVQLG
IDLTGIVTRANLQSGIEYALDLQGLAIRPR

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 29751; Mature: 29620

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNYYEMFKQHEESIVETIITTLQTQIPTYGKISRDDVRKRVIAGLDPYARDLDTEHPKA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCC
FPDYWRETSYLRAQQGIPIGDFLQVLLLSTDIMIQGLRQAYPDSTADQINVIEKGHQITT
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHH
AAIAAVYEGFQQHKDEIISSQTYALAEVSSPIVPVYEGVLVLPLIGSIDSMRAGQIMESL
HHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHCCHHHHHHHCCCCHHHHHHHHHHH
LESINTYSADVVILDITGVPVIDTGVANYLLQSARAARLLGSTVVLVGIGAEIAQTIVQL
HHHHHCCCCCEEEEEECCCCEEHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHH
GIDLTGIVTRANLQSGIEYALDLQGLAIRPR
CCCHHHHHHHHHHHHHHHHHEECCCEEECCC
>Mature Secondary Structure 
TNYYEMFKQHEESIVETIITTLQTQIPTYGKISRDDVRKRVIAGLDPYARDLDTEHPKA
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCC
FPDYWRETSYLRAQQGIPIGDFLQVLLLSTDIMIQGLRQAYPDSTADQINVIEKGHQITT
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHH
AAIAAVYEGFQQHKDEIISSQTYALAEVSSPIVPVYEGVLVLPLIGSIDSMRAGQIMESL
HHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHCCHHHHHHHCCCCHHHHHHHHHHH
LESINTYSADVVILDITGVPVIDTGVANYLLQSARAARLLGSTVVLVGIGAEIAQTIVQL
HHHHHCCCCCEEEEEECCCCEEHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHH
GIDLTGIVTRANLQSGIEYALDLQGLAIRPR
CCCHHHHHHHHHHHHHHHHHEECCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]