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The map label for this gene is gap3 [H]

Identifier: 159899848

GI number: 159899848

Start: 4199713

End: 4200726

Strand: Direct

Name: gap3 [H]

Synonym: Haur_3331

Alternate gene names: 159899848

Gene position: 4199713-4200726 (Clockwise)

Preceding gene: 159899847

Following gene: 159899849

Centisome position: 66.17

GC content: 50.79

Gene sequence:

>1014_bases
ATGGCTTTACGAATTGGCATTAATGGCTTTGGGCGCATGGGGCGGCTCGCATTACGGGCTGGCTGGAATCGCCCAGGATT
TGAATGGGTGCATATCAACGAACTCAAAGGCGATGCTGCAACCGCCGCCCATTTACTGGCTTTTGATTCAGTTCATGGCC
GCTGGAATCATGGAGTCTCATCGCAAGAGCAAGCCCTGATGATCGAGCAACAACGCCTGAGTTATAGCAATCATTCAACA
ATTGAAGCAACCGATTGGGCTAGCCATGAGGTTGATCTGGTGCTGGAATGCTCAGGCAAATTTCGTAGCCCAGAGCAACT
AGCTGGCTATTTTGCGGCTGGAGTTAAAACCGTGATCGTTGCCGCACCCGTAAAACAGGGTGCACTCAACATCGTGATGG
GAGTTAATGATCAGCTTTATGATCCGCAGCAGCATCGTTTATTAACTGCCGCCTCGTGCACCACCAATTGTTTAGCGCCC
ATTGTCAAAGTTGTGCATGAACAATTCGGCATTAAGCATGGCATGATCACCACAATTCACGATATGACCAATACCCAAAA
TCTGATCGATGCACCGCACAAAGATTTACGCCGTGCCCGCGCCGCCAGCCAATCGCTGATTCCTACCAGCACAGGCTCAG
CCAGCGCAATTGGCATGATCTTTCCAGAATTAGCAGGTCGTTTGGATGGTGTGGCGATTCGCGTGCCTTTGTTGAATGCC
TCGCTGACCGATTGTGTCTTTGAATTGGCCCAACCAACCACCAGTGAAGCGGTTAATCGGGCTTTGGCGGAGGCTAGTCG
CGGAGCGCTCAAAGACATTTTGGGCTATGAAGAACGGCCCTTAGTTTCAGTCGATTACAAGGGCGATCCACGTTCGGCGA
TTATCGATGCAGCGCTGACGACCGTTACCAACCAAACTCAATTGAAAATTATGGCTTGGTACGACAACGAAATTGGCTAT
GTGAATCGAATGTTGGAGCTAGCCGCTAAGGTCGCCCAACTTCAGGCGGGCTAG

Upstream 100 bases:

>100_bases
CCCAAGCTGCCACAATTGAAACCACCGCCCAGCAACTGATGACGCGCATTCGCTTTTTGCTGACCACAATCGAGCGCCAA
CAACGTGAAGGGAGCAAATA

Downstream 100 bases:

>100_bases
GAGCCGACTATGCAGCAACAATTCAAAGAGTATGCGATTGTTACCGCCGCTTATTGGGCCTTTACATTGACCGATGGCGC
GTTGCGTATGTTGGTCTTGT

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MALRIGINGFGRMGRLALRAGWNRPGFEWVHINELKGDAATAAHLLAFDSVHGRWNHGVSSQEQALMIEQQRLSYSNHST
IEATDWASHEVDLVLECSGKFRSPEQLAGYFAAGVKTVIVAAPVKQGALNIVMGVNDQLYDPQQHRLLTAASCTTNCLAP
IVKVVHEQFGIKHGMITTIHDMTNTQNLIDAPHKDLRRARAASQSLIPTSTGSASAIGMIFPELAGRLDGVAIRVPLLNA
SLTDCVFELAQPTTSEAVNRALAEASRGALKDILGYEERPLVSVDYKGDPRSAIIDAALTTVTNQTQLKIMAWYDNEIGY
VNRMLELAAKVAQLQAG

Sequences:

>Translated_337_residues
MALRIGINGFGRMGRLALRAGWNRPGFEWVHINELKGDAATAAHLLAFDSVHGRWNHGVSSQEQALMIEQQRLSYSNHST
IEATDWASHEVDLVLECSGKFRSPEQLAGYFAAGVKTVIVAAPVKQGALNIVMGVNDQLYDPQQHRLLTAASCTTNCLAP
IVKVVHEQFGIKHGMITTIHDMTNTQNLIDAPHKDLRRARAASQSLIPTSTGSASAIGMIFPELAGRLDGVAIRVPLLNA
SLTDCVFELAQPTTSEAVNRALAEASRGALKDILGYEERPLVSVDYKGDPRSAIIDAALTTVTNQTQLKIMAWYDNEIGY
VNRMLELAAKVAQLQAG
>Mature_336_residues
ALRIGINGFGRMGRLALRAGWNRPGFEWVHINELKGDAATAAHLLAFDSVHGRWNHGVSSQEQALMIEQQRLSYSNHSTI
EATDWASHEVDLVLECSGKFRSPEQLAGYFAAGVKTVIVAAPVKQGALNIVMGVNDQLYDPQQHRLLTAASCTTNCLAPI
VKVVHEQFGIKHGMITTIHDMTNTQNLIDAPHKDLRRARAASQSLIPTSTGSASAIGMIFPELAGRLDGVAIRVPLLNAS
LTDCVFELAQPTTSEAVNRALAEASRGALKDILGYEERPLVSVDYKGDPRSAIIDAALTTVTNQTQLKIMAWYDNEIGYV
NRMLELAAKVAQLQAG

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=334, Percent_Identity=37.7245508982036, Blast_Score=254, Evalue=9e-68,
Organism=Homo sapiens, GI7657116, Length=326, Percent_Identity=38.3435582822086, Blast_Score=248, Evalue=6e-66,
Organism=Escherichia coli, GI1788079, Length=334, Percent_Identity=39.2215568862275, Blast_Score=261, Evalue=5e-71,
Organism=Escherichia coli, GI1789295, Length=339, Percent_Identity=39.8230088495575, Blast_Score=251, Evalue=5e-68,
Organism=Caenorhabditis elegans, GI17534677, Length=335, Percent_Identity=37.0149253731343, Blast_Score=249, Evalue=1e-66,
Organism=Caenorhabditis elegans, GI17534679, Length=335, Percent_Identity=36.7164179104478, Blast_Score=248, Evalue=2e-66,
Organism=Caenorhabditis elegans, GI17568413, Length=334, Percent_Identity=36.8263473053892, Blast_Score=244, Evalue=6e-65,
Organism=Caenorhabditis elegans, GI32566163, Length=334, Percent_Identity=36.8263473053892, Blast_Score=244, Evalue=6e-65,
Organism=Saccharomyces cerevisiae, GI6321631, Length=332, Percent_Identity=37.9518072289157, Blast_Score=262, Evalue=5e-71,
Organism=Saccharomyces cerevisiae, GI6322468, Length=332, Percent_Identity=37.9518072289157, Blast_Score=260, Evalue=2e-70,
Organism=Saccharomyces cerevisiae, GI6322409, Length=332, Percent_Identity=37.9518072289157, Blast_Score=258, Evalue=9e-70,
Organism=Drosophila melanogaster, GI19922412, Length=324, Percent_Identity=37.962962962963, Blast_Score=250, Evalue=9e-67,
Organism=Drosophila melanogaster, GI85725000, Length=325, Percent_Identity=38.4615384615385, Blast_Score=246, Evalue=1e-65,
Organism=Drosophila melanogaster, GI22023983, Length=325, Percent_Identity=38.4615384615385, Blast_Score=246, Evalue=1e-65,
Organism=Drosophila melanogaster, GI17933600, Length=325, Percent_Identity=37.8461538461538, Blast_Score=243, Evalue=1e-64,
Organism=Drosophila melanogaster, GI18110149, Length=325, Percent_Identity=37.8461538461538, Blast_Score=243, Evalue=1e-64,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36590; Mature: 36459

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALRIGINGFGRMGRLALRAGWNRPGFEWVHINELKGDAATAAHLLAFDSVHGRWNHGVS
CEEEEECCCCCHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCC
SQEQALMIEQQRLSYSNHSTIEATDWASHEVDLVLECSGKFRSPEQLAGYFAAGVKTVIV
CCHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCEEEEE
AAPVKQGALNIVMGVNDQLYDPQQHRLLTAASCTTNCLAPIVKVVHEQFGIKHGMITTIH
ECCCCCCCEEEEECCCCCCCCCHHHCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEH
DMTNTQNLIDAPHKDLRRARAASQSLIPTSTGSASAIGMIFPELAGRLDGVAIRVPLLNA
HHCCCHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCC
SLTDCVFELAQPTTSEAVNRALAEASRGALKDILGYEERPLVSVDYKGDPRSAIIDAALT
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHH
TVTNQTQLKIMAWYDNEIGYVNRMLELAAKVAQLQAG
HHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ALRIGINGFGRMGRLALRAGWNRPGFEWVHINELKGDAATAAHLLAFDSVHGRWNHGVS
EEEEECCCCCHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCC
SQEQALMIEQQRLSYSNHSTIEATDWASHEVDLVLECSGKFRSPEQLAGYFAAGVKTVIV
CCHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCEEEEE
AAPVKQGALNIVMGVNDQLYDPQQHRLLTAASCTTNCLAPIVKVVHEQFGIKHGMITTIH
ECCCCCCCEEEEECCCCCCCCCHHHCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEH
DMTNTQNLIDAPHKDLRRARAASQSLIPTSTGSASAIGMIFPELAGRLDGVAIRVPLLNA
HHCCCHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCC
SLTDCVFELAQPTTSEAVNRALAEASRGALKDILGYEERPLVSVDYKGDPRSAIIDAALT
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHH
TVTNQTQLKIMAWYDNEIGYVNRMLELAAKVAQLQAG
HHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8378350 [H]