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The map label for this gene is arsC [H]

Identifier: 159899847

GI number: 159899847

Start: 4198940

End: 4199713

Strand: Direct

Name: arsC [H]

Synonym: Haur_3330

Alternate gene names: 159899847

Gene position: 4198940-4199713 (Clockwise)

Preceding gene: 159899845

Following gene: 159899848

Centisome position: 66.16

GC content: 51.94

Gene sequence:

>774_bases
ATGCAAAGTCTTGGGCTTGAACCACCTGTTGTGCTCAAATTGCTATCGCACGATCTCCGTTGGCGCTTGTTACAACTTTT
AGTCCATAGTGATTATCGGGTGCATGAATGTGTGGCGGCCTTGCAAGCACCAATGAATGTGGTTTCCTATCATTTACGGC
TACTACGCGAAGCCGCCTTGGTGATCGAACGCCGCAGCGAAGCCGATGGCCGTGATGTCTATTACCATCTCGATTTGCCA
AGCTTGCAAACCGCCTACCAAGCGAGTGCCCAAGCCCTGCACCCTGATCTTGATCCATTTGCCGCCAAAACCACCAGCCA
AGCCTATCAACTTAGCAAACCAGTGCGGATTTTATATTTGTGCACCCACAACAGTGCTCGCTCACAGTTGGCCGAGGCAA
TTACCCGCCATCTCGGTGGCTCCATGCTTGATGTAGTGAGCGCCGGAACCCAACCTGCCGAGGTGAATCCTTTGGTCTTA
GCTACTTTGGAAGAAAAAAAGATTTCGAGTGCTGGCCTGTATTCCAAGACACTCCAGCCTTACCTTGAGCAAGATTTCGA
TTATGTGATTACGGTCTGCGATCGCGCTCGTGAACAATGCCCAACGCTTGCTGGCCATCCCACCAGCATGCACTGGAGTT
TTGCCGACCCGCTGCGTGAAACCAGCGAACTAGCCCAAGCTGCCACAATTGAAACCACCGCCCAGCAACTGATGACGCGC
ATTCGCTTTTTGCTGACCACAATCGAGCGCCAACAACGTGAAGGGAGCAAATAA

Upstream 100 bases:

>100_bases
AATCGATGCGCCAGCATCCATCAACATTCATACTTGCTTTTTTGCAATATCGCCAATATACTTCAAAATAATTTGAAACA
ATTTAATTTGGAGTGTTTTT

Downstream 100 bases:

>100_bases
TGGCTTTACGAATTGGCATTAATGGCTTTGGGCGCATGGGGCGGCTCGCATTACGGGCTGGCTGGAATCGCCCAGGATTT
GAATGGGTGCATATCAACGA

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MQSLGLEPPVVLKLLSHDLRWRLLQLLVHSDYRVHECVAALQAPMNVVSYHLRLLREAALVIERRSEADGRDVYYHLDLP
SLQTAYQASAQALHPDLDPFAAKTTSQAYQLSKPVRILYLCTHNSARSQLAEAITRHLGGSMLDVVSAGTQPAEVNPLVL
ATLEEKKISSAGLYSKTLQPYLEQDFDYVITVCDRAREQCPTLAGHPTSMHWSFADPLRETSELAQAATIETTAQQLMTR
IRFLLTTIERQQREGSK

Sequences:

>Translated_257_residues
MQSLGLEPPVVLKLLSHDLRWRLLQLLVHSDYRVHECVAALQAPMNVVSYHLRLLREAALVIERRSEADGRDVYYHLDLP
SLQTAYQASAQALHPDLDPFAAKTTSQAYQLSKPVRILYLCTHNSARSQLAEAITRHLGGSMLDVVSAGTQPAEVNPLVL
ATLEEKKISSAGLYSKTLQPYLEQDFDYVITVCDRAREQCPTLAGHPTSMHWSFADPLRETSELAQAATIETTAQQLMTR
IRFLLTTIERQQREGSK
>Mature_257_residues
MQSLGLEPPVVLKLLSHDLRWRLLQLLVHSDYRVHECVAALQAPMNVVSYHLRLLREAALVIERRSEADGRDVYYHLDLP
SLQTAYQASAQALHPDLDPFAAKTTSQAYQLSKPVRILYLCTHNSARSQLAEAITRHLGGSMLDVVSAGTQPAEVNPLVL
ATLEEKKISSAGLYSKTLQPYLEQDFDYVITVCDRAREQCPTLAGHPTSMHWSFADPLRETSELAQAATIETTAQQLMTR
IRFLLTTIERQQREGSK

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 28846; Mature: 28846

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSLGLEPPVVLKLLSHDLRWRLLQLLVHSDYRVHECVAALQAPMNVVSYHLRLLREAAL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIERRSEADGRDVYYHLDLPSLQTAYQASAQALHPDLDPFAAKTTSQAYQLSKPVRILYL
HHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEEE
CTHNSARSQLAEAITRHLGGSMLDVVSAGTQPAEVNPLVLATLEEKKISSAGLYSKTLQP
EECCHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCEEEEECHHHHHHHCCHHHHHHHH
YLEQDFDYVITVCDRAREQCPTLAGHPTSMHWSFADPLRETSELAQAATIETTAQQLMTR
HHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRFLLTTIERQQREGSK
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQSLGLEPPVVLKLLSHDLRWRLLQLLVHSDYRVHECVAALQAPMNVVSYHLRLLREAAL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIERRSEADGRDVYYHLDLPSLQTAYQASAQALHPDLDPFAAKTTSQAYQLSKPVRILYL
HHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEEE
CTHNSARSQLAEAITRHLGGSMLDVVSAGTQPAEVNPLVLATLEEKKISSAGLYSKTLQP
EECCHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCEEEEECHHHHHHHCCHHHHHHHH
YLEQDFDYVITVCDRAREQCPTLAGHPTSMHWSFADPLRETSELAQAATIETTAQQLMTR
HHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRFLLTTIERQQREGSK
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]