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The map label for this gene is phoP [H]

Identifier: 159899580

GI number: 159899580

Start: 3867620

End: 3868303

Strand: Direct

Name: phoP [H]

Synonym: Haur_3061

Alternate gene names: 159899580

Gene position: 3867620-3868303 (Clockwise)

Preceding gene: 159899579

Following gene: 159899581

Centisome position: 60.94

GC content: 50.58

Gene sequence:

>684_bases
ATGAGCGCAAAGATTTTAATTGTTGAAGACGAGCGCAAAATAGCAGTTGGTTTACAAAATTATTTAGAGGGCGTAGGCTA
TAGCACCATCACCGCCAGCGATGGCCAAGCTGGCCTCGATATGGCACGGCGCGAGCAGCCCGATTTAGTTTTGCTCGATT
TGATGTTGCCTATGGTTGATGGCTTTACGGTTTGTCGTACCTTACGCGCTGAATCAAGCGTGCCAATTATTATGTTAACT
GCTCGGGTCGAGGAAGTCGATTCATTGGCAGGCTTGGAGTTGGGCGCTGACGATTATATTACCAAGCCATTTTCGCCGCG
CCAAGTCGTTGCTCGGATCAAAGCCGTACTACGCCGCGTTAATGGCGAGCTAGAGCCACCCATGATTGTGCGCAAAAGTG
GGATTGAGATCGACTTGCAACGCCGCACCGTCGTGATTGAGCAAAACCCGATCACCAGCCTAACGCCCACCGAATTTGAT
TTATTGGTAACTTTAGTGCGCTCAGCAGGTCGCCCCTTGACCCGTAGCCAATTGCTTGATGCGGTGCAGGGGGAAGAAGG
CGAGGCTTATGATCGCACCGTCGATGCGCATATCAAAAATGTCCGCCGTAAGATCGAGCCAAATCCTAGCGTTCCGCGCT
ATATTTTGACGGTCTTTGGTGTGGGCTACAAATTTGCGGAATAA

Upstream 100 bases:

>100_bases
AAGCAACGCAAACGGCTAGTTTTTTCGCGCAAATAAGCTTTCTTCGCAGATTCTTCACGGGTTCAGGCTACAATACAACC
ATCACCCAGTGGAGGCTTGT

Downstream 100 bases:

>100_bases
GCTATGAAACTGCAACGAAAATTATTATTAACCCACATCGCAGTTGCCCTCGTTGCAATTTTGCTGATTACGGCGGTGGC
CAACTTCACCGTCAATCGCT

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MSAKILIVEDERKIAVGLQNYLEGVGYSTITASDGQAGLDMARREQPDLVLLDLMLPMVDGFTVCRTLRAESSVPIIMLT
ARVEEVDSLAGLELGADDYITKPFSPRQVVARIKAVLRRVNGELEPPMIVRKSGIEIDLQRRTVVIEQNPITSLTPTEFD
LLVTLVRSAGRPLTRSQLLDAVQGEEGEAYDRTVDAHIKNVRRKIEPNPSVPRYILTVFGVGYKFAE

Sequences:

>Translated_227_residues
MSAKILIVEDERKIAVGLQNYLEGVGYSTITASDGQAGLDMARREQPDLVLLDLMLPMVDGFTVCRTLRAESSVPIIMLT
ARVEEVDSLAGLELGADDYITKPFSPRQVVARIKAVLRRVNGELEPPMIVRKSGIEIDLQRRTVVIEQNPITSLTPTEFD
LLVTLVRSAGRPLTRSQLLDAVQGEEGEAYDRTVDAHIKNVRRKIEPNPSVPRYILTVFGVGYKFAE
>Mature_226_residues
SAKILIVEDERKIAVGLQNYLEGVGYSTITASDGQAGLDMARREQPDLVLLDLMLPMVDGFTVCRTLRAESSVPIIMLTA
RVEEVDSLAGLELGADDYITKPFSPRQVVARIKAVLRRVNGELEPPMIVRKSGIEIDLQRRTVVIEQNPITSLTPTEFDL
LVTLVRSAGRPLTRSQLLDAVQGEEGEAYDRTVDAHIKNVRRKIEPNPSVPRYILTVFGVGYKFAE

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=45.0892857142857, Blast_Score=187, Evalue=3e-49,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=41.2280701754386, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=42.6008968609865, Blast_Score=164, Evalue=6e-42,
Organism=Escherichia coli, GI1786599, Length=233, Percent_Identity=40.7725321888412, Blast_Score=160, Evalue=7e-41,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=40.0900900900901, Blast_Score=160, Evalue=7e-41,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=34.1991341991342, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=34.2222222222222, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=35.5555555555556, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=36.4035087719298, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=34.4827586206897, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=37.10407239819, Blast_Score=117, Evalue=4e-28,
Organism=Escherichia coli, GI1790552, Length=221, Percent_Identity=34.841628959276, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=34.051724137931, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=30.3571428571429, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1788550, Length=102, Percent_Identity=34.3137254901961, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI1788521, Length=223, Percent_Identity=27.3542600896861, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25176; Mature: 25044

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAKILIVEDERKIAVGLQNYLEGVGYSTITASDGQAGLDMARREQPDLVLLDLMLPMVD
CCCEEEEEECCCHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHCCCCCEEHHHHHHHHHC
GFTVCRTLRAESSVPIIMLTARVEEVDSLAGLELGADDYITKPFSPRQVVARIKAVLRRV
HHHHHHHHHCCCCCCEEEEECCHHHHHHHHCCEECCCCCCCCCCCHHHHHHHHHHHHHHH
NGELEPPMIVRKSGIEIDLQRRTVVIEQNPITSLTPTEFDLLVTLVRSAGRPLTRSQLLD
CCCCCCCEEEECCCCEEEEECEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHH
AVQGEEGEAYDRTVDAHIKNVRRKIEPNPSVPRYILTVFGVGYKFAE
HHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SAKILIVEDERKIAVGLQNYLEGVGYSTITASDGQAGLDMARREQPDLVLLDLMLPMVD
CCEEEEEECCCHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHCCCCCEEHHHHHHHHHC
GFTVCRTLRAESSVPIIMLTARVEEVDSLAGLELGADDYITKPFSPRQVVARIKAVLRRV
HHHHHHHHHCCCCCCEEEEECCHHHHHHHHCCEECCCCCCCCCCCHHHHHHHHHHHHHHH
NGELEPPMIVRKSGIEIDLQRRTVVIEQNPITSLTPTEFDLLVTLVRSAGRPLTRSQLLD
CCCCCCCEEEECCCCEEEEECEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHH
AVQGEEGEAYDRTVDAHIKNVRRKIEPNPSVPRYILTVFGVGYKFAE
HHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]