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The map label for this gene is pdhS [H]

Identifier: 159897671

GI number: 159897671

Start: 1306365

End: 1308260

Strand: Reverse

Name: pdhS [H]

Synonym: Haur_1142

Alternate gene names: 159897671

Gene position: 1308260-1306365 (Counterclockwise)

Preceding gene: 159897674

Following gene: 159897670

Centisome position: 20.61

GC content: 48.79

Gene sequence:

>1896_bases
ATGCCTCGGAAATTGAAATGGCCACTCGCTGGAGCATGGCAACGCCGCTTGATTAAAGCAACTCGCCGTAAAGATGTAAC
GCTTGAGCAATTTCCGGTTGGCTTGGTTTGGTTTCAAGGCTCACAGGTTTTTTTTAATCAAGCGGTCACGGCGATGATTG
GCTATAGCAATGCGGAAATTGCGACAACTGAGCAATGGTTTAGCACCTTGTATGGCCCTGAAGCCGCCAGCATGCGCCAA
TTGTATGCAACAACCTCGGCAGCGACCTTAGGCCAGACAATCCATGGCTTTGTCGTGAATCGCCAGAACCAAAGTTGCCT
TTTAGAATGTACGTTGGCTTCCCATGGCCATCGTCAGGTTTGGTTGGTACGCGATATTACCGAGAGCAATCGGCTTGAGC
GCTTGCTGTTGCAAACTGAACAAACCGCCCGCGTCGGCGGCTGGGAGATCGATTTGCGCACCAACCAAGTATTTTGGACG
CGCGAAATGTACCATATTTTGGATACCACAGCACACGAATACACGCCCACGATTGAGAATCAGAATTTTTTCCATACCAA
TGCCACGTTAATCCAACTTGAGGCAATTTTTCGCCAAATGATCGAGCAGCGTGGCTCGTTTGATATGAGTGTGGAAATGC
GGACGTTTCGGGGGCGTTCGTTCTGGGGTCGTTTTACTGGGCGAGTTGAGCTAGAGTTTGGCCAGCCAATCAAAATTTAT
GGCTCGTTGCAAGATGTAACTGAGCACCATCAATTAACTGAGGCCTTGCGGGTGGCCGAGCACGACTATCGCACAATTTT
TGAAACCACCAAAATTGGCATCTTTCGCATTACTCCCGATGGACGGGTGTTACGGGCTAATCCGGCGTTGGTGCGCTTGG
CGGGCTTTGCCCATGAACATGAATTGGTCGATTATGTGGCCGATTTAACCACGATGTATGTTGAGCCGCAGCGCTTTGAA
TACTTGCGTGAGCTGCTGCAAACCAATGGCTCGTATGATGAAATTGAATCGGAAGTTTATCGGCCTGCCACTGGCGAACG
GATTTGGATCAGCGAGACCTCGCGTTTGGTGTATGCTGAGGATGGCTCGATGCTCTACGCCGAAGGCACGATTCAAGAAA
TTACGGCACGCAAACAGGTCGAAGAGGCGTTGCGCCATGCCCGTGATGCTGCCGAAGCCGCCAATCATGCCAAAAGCACT
TTTTTGGCCAATATGAGCCACGAGCTGCGCACGCCACTGAATGCAATTATTGGCTATAGCGAATTGCTGATGGACGATAC
TGATTTTGATGATCCGACGATGGTTGAGCAGTTTCGCCATGATATTGCGCAAATTAATGATGCAGGTCATCAATTGCTCA
ATTTGGTCAACGATGTGCTTGATTTGGCCAAAGTTGAGGCTGGCAAATATCAAGTTGCTGCTGAAACCTTCGATCTCAAC
AGCCTTGTACGTGATTTGATTGCCACAATTAACCCAATGGCTCAGAAAAATGCCAATAGCCTTTACTTTGAGCCAAACAA
ACATCTGCCGTTAATTCATACTGATCGCTCGATGTTGCGCCAGATTTTGCTGAATTTATTGAGTAATGCCGCCAAATTTA
CCAAAGCAGGCAGCATCAACATCAGCGTCAGCTTTGATCCAGCCAGCCAACATGTGCAATGTCGGGTGCGCGATACTGGC
ATTGGTATGAACGATGAGCAAATGCAGCGTTTGTTTGAGCCATTTACCCAAGGTGATGCCTCGACGACGCGGCGCTATGG
TGGCACTGGCTTGGGCTTGGCGCTTTGTCGCCATTTTATCGAACTATTGAATGGCTCAATTCAAGTTGAAAGTGTCTTTG
GCCAAGGCTCGATCTTTACCATTGTCTTTCCATGCTTGGTTGAGGCAATTGATTAG

Upstream 100 bases:

>100_bases
ATTGGCTTAAAAAGCCGCTAAAACTACTTGGATCGTGGGCTTTCTCATACTACAATACAGCATAGACCTTAGGCTTGAAA
CTTGTGTTGTGAGGATCGTT

Downstream 100 bases:

>100_bases
GCAGATTGCTACATACTTTGGGAATTTAAGCATGCTGGCTGAGGCCGCTAGCGGCAAGCAATTTAACAACCTTTTGTGCA
CTTTGTACAAATAGCGTGAT

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 631; Mature: 630

Protein sequence:

>631_residues
MPRKLKWPLAGAWQRRLIKATRRKDVTLEQFPVGLVWFQGSQVFFNQAVTAMIGYSNAEIATTEQWFSTLYGPEAASMRQ
LYATTSAATLGQTIHGFVVNRQNQSCLLECTLASHGHRQVWLVRDITESNRLERLLLQTEQTARVGGWEIDLRTNQVFWT
REMYHILDTTAHEYTPTIENQNFFHTNATLIQLEAIFRQMIEQRGSFDMSVEMRTFRGRSFWGRFTGRVELEFGQPIKIY
GSLQDVTEHHQLTEALRVAEHDYRTIFETTKIGIFRITPDGRVLRANPALVRLAGFAHEHELVDYVADLTTMYVEPQRFE
YLRELLQTNGSYDEIESEVYRPATGERIWISETSRLVYAEDGSMLYAEGTIQEITARKQVEEALRHARDAAEAANHAKST
FLANMSHELRTPLNAIIGYSELLMDDTDFDDPTMVEQFRHDIAQINDAGHQLLNLVNDVLDLAKVEAGKYQVAAETFDLN
SLVRDLIATINPMAQKNANSLYFEPNKHLPLIHTDRSMLRQILLNLLSNAAKFTKAGSINISVSFDPASQHVQCRVRDTG
IGMNDEQMQRLFEPFTQGDASTTRRYGGTGLGLALCRHFIELLNGSIQVESVFGQGSIFTIVFPCLVEAID

Sequences:

>Translated_631_residues
MPRKLKWPLAGAWQRRLIKATRRKDVTLEQFPVGLVWFQGSQVFFNQAVTAMIGYSNAEIATTEQWFSTLYGPEAASMRQ
LYATTSAATLGQTIHGFVVNRQNQSCLLECTLASHGHRQVWLVRDITESNRLERLLLQTEQTARVGGWEIDLRTNQVFWT
REMYHILDTTAHEYTPTIENQNFFHTNATLIQLEAIFRQMIEQRGSFDMSVEMRTFRGRSFWGRFTGRVELEFGQPIKIY
GSLQDVTEHHQLTEALRVAEHDYRTIFETTKIGIFRITPDGRVLRANPALVRLAGFAHEHELVDYVADLTTMYVEPQRFE
YLRELLQTNGSYDEIESEVYRPATGERIWISETSRLVYAEDGSMLYAEGTIQEITARKQVEEALRHARDAAEAANHAKST
FLANMSHELRTPLNAIIGYSELLMDDTDFDDPTMVEQFRHDIAQINDAGHQLLNLVNDVLDLAKVEAGKYQVAAETFDLN
SLVRDLIATINPMAQKNANSLYFEPNKHLPLIHTDRSMLRQILLNLLSNAAKFTKAGSINISVSFDPASQHVQCRVRDTG
IGMNDEQMQRLFEPFTQGDASTTRRYGGTGLGLALCRHFIELLNGSIQVESVFGQGSIFTIVFPCLVEAID
>Mature_630_residues
PRKLKWPLAGAWQRRLIKATRRKDVTLEQFPVGLVWFQGSQVFFNQAVTAMIGYSNAEIATTEQWFSTLYGPEAASMRQL
YATTSAATLGQTIHGFVVNRQNQSCLLECTLASHGHRQVWLVRDITESNRLERLLLQTEQTARVGGWEIDLRTNQVFWTR
EMYHILDTTAHEYTPTIENQNFFHTNATLIQLEAIFRQMIEQRGSFDMSVEMRTFRGRSFWGRFTGRVELEFGQPIKIYG
SLQDVTEHHQLTEALRVAEHDYRTIFETTKIGIFRITPDGRVLRANPALVRLAGFAHEHELVDYVADLTTMYVEPQRFEY
LRELLQTNGSYDEIESEVYRPATGERIWISETSRLVYAEDGSMLYAEGTIQEITARKQVEEALRHARDAAEAANHAKSTF
LANMSHELRTPLNAIIGYSELLMDDTDFDDPTMVEQFRHDIAQINDAGHQLLNLVNDVLDLAKVEAGKYQVAAETFDLNS
LVRDLIATINPMAQKNANSLYFEPNKHLPLIHTDRSMLRQILLNLLSNAAKFTKAGSINISVSFDPASQHVQCRVRDTGI
GMNDEQMQRLFEPFTQGDASTTRRYGGTGLGLALCRHFIELLNGSIQVESVFGQGSIFTIVFPCLVEAID

Specific function: Functions as a polar differentiation marker. Essential protein that, by localizing in the old pole of dividing cells, controls cell division and maturation, probably through control of DivK phosphorylation status and cellular distribution, which in turn r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm. Note=Localizes at the old pole of dividing cells. Colocalizes with divK (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=254, Percent_Identity=36.6141732283465, Blast_Score=162, Evalue=5e-41,
Organism=Escherichia coli, GI1789149, Length=237, Percent_Identity=37.1308016877637, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI48994928, Length=269, Percent_Identity=35.3159851301115, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1788713, Length=259, Percent_Identity=33.976833976834, Blast_Score=142, Evalue=7e-35,
Organism=Escherichia coli, GI87081816, Length=246, Percent_Identity=34.1463414634146, Blast_Score=129, Evalue=8e-31,
Organism=Escherichia coli, GI1788549, Length=377, Percent_Identity=27.0557029177719, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1786912, Length=289, Percent_Identity=28.3737024221453, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1786600, Length=228, Percent_Identity=30.2631578947368, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1790436, Length=224, Percent_Identity=31.6964285714286, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1788393, Length=285, Percent_Identity=28.0701754385965, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1790861, Length=238, Percent_Identity=28.9915966386555, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1789808, Length=235, Percent_Identity=26.3829787234043, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1786783, Length=249, Percent_Identity=26.1044176706827, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788279, Length=227, Percent_Identity=26.431718061674, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI87082128, Length=225, Percent_Identity=27.5555555555556, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1790346, Length=237, Percent_Identity=25.7383966244726, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1790551, Length=209, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=79, Percent_Identity=40.5063291139241, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 71845; Mature: 71714

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRKLKWPLAGAWQRRLIKATRRKDVTLEQFPVGLVWFQGSQVFFNQAVTAMIGYSNAEI
CCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCEEEEEECCCHHHHHHHHHHHHCCCCCCE
ATTEQWFSTLYGPEAASMRQLYATTSAATLGQTIHGFVVNRQNQSCLLECTLASHGHRQV
EEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCEEEEEEECCCCCCEE
WLVRDITESNRLERLLLQTEQTARVGGWEIDLRTNQVFWTREMYHILDTTAHEYTPTIEN
EEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEHHHHHHHHHCCCCCCCCCCCC
QNFFHTNATLIQLEAIFRQMIEQRGSFDMSVEMRTFRGRSFWGRFTGRVELEFGQPIKIY
CCEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEECEEEEEECCCCEEEE
GSLQDVTEHHQLTEALRVAEHDYRTIFETTKIGIFRITPDGRVLRANPALVRLAGFAHEH
ECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCEEEECCCCEEEEECCCHHH
ELVDYVADLTTMYVEPQRFEYLRELLQTNGSYDEIESEVYRPATGERIWISETSRLVYAE
HHHHHHHHHHHHEECHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEECCCEEEEEC
DGSMLYAEGTIQEITARKQVEEALRHARDAAEAANHAKSTFLANMSHELRTPLNAIIGYS
CCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCHHHHHHCHH
ELLMDDTDFDDPTMVEQFRHDIAQINDAGHQLLNLVNDVLDLAKVEAGKYQVAAETFDLN
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHH
SLVRDLIATINPMAQKNANSLYFEPNKHLPLIHTDRSMLRQILLNLLSNAAKFTKAGSIN
HHHHHHHHHCCHHHHCCCCCEEECCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCEEE
ISVSFDPASQHVQCRVRDTGIGMNDEQMQRLFEPFTQGDASTTRRYGGTGLGLALCRHFI
EEEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHH
ELLNGSIQVESVFGQGSIFTIVFPCLVEAID
HHHCCCEEEEEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
PRKLKWPLAGAWQRRLIKATRRKDVTLEQFPVGLVWFQGSQVFFNQAVTAMIGYSNAEI
CCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCEEEEEECCCHHHHHHHHHHHHCCCCCCE
ATTEQWFSTLYGPEAASMRQLYATTSAATLGQTIHGFVVNRQNQSCLLECTLASHGHRQV
EEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCEEEEEEECCCCCCEE
WLVRDITESNRLERLLLQTEQTARVGGWEIDLRTNQVFWTREMYHILDTTAHEYTPTIEN
EEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEHHHHHHHHHCCCCCCCCCCCC
QNFFHTNATLIQLEAIFRQMIEQRGSFDMSVEMRTFRGRSFWGRFTGRVELEFGQPIKIY
CCEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEECEEEEEECCCCEEEE
GSLQDVTEHHQLTEALRVAEHDYRTIFETTKIGIFRITPDGRVLRANPALVRLAGFAHEH
ECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCEEEECCCCEEEEECCCHHH
ELVDYVADLTTMYVEPQRFEYLRELLQTNGSYDEIESEVYRPATGERIWISETSRLVYAE
HHHHHHHHHHHHEECHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEECCCEEEEEC
DGSMLYAEGTIQEITARKQVEEALRHARDAAEAANHAKSTFLANMSHELRTPLNAIIGYS
CCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCHHHHHHCHH
ELLMDDTDFDDPTMVEQFRHDIAQINDAGHQLLNLVNDVLDLAKVEAGKYQVAAETFDLN
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHH
SLVRDLIATINPMAQKNANSLYFEPNKHLPLIHTDRSMLRQILLNLLSNAAKFTKAGSIN
HHHHHHHHHCCHHHHCCCCCEEECCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCEEE
ISVSFDPASQHVQCRVRDTGIGMNDEQMQRLFEPFTQGDASTTRRYGGTGLGLALCRHFI
EEEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHH
ELLNGSIQVESVFGQGSIFTIVFPCLVEAID
HHHCCCEEEEEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA