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The map label for this gene is yycF [H]

Identifier: 159897347

GI number: 159897347

Start: 925874

End: 926677

Strand: Reverse

Name: yycF [H]

Synonym: Haur_0818

Alternate gene names: 159897347

Gene position: 926677-925874 (Counterclockwise)

Preceding gene: 159897348

Following gene: 159897345

Centisome position: 14.6

GC content: 51.87

Gene sequence:

>804_bases
ATGAGTCAAGCTTCGATTTTATTAGTTGATGATGAATTTCCCATTCGCGCCACCCTCGGCGATTTACTGCGGCGACGGGG
CTACGATGTGCAAACTGCCGATAGCGGAGAGGAAGCACTCGACCGCATTGCCCAACGGCCTTTCGATTTGTTTCTTTTGG
ATTTGCGCTTGCCTGGCGTTGATGGCATTACCGTGGCGCAACGGGTACGCGAACGCTATCCCGATGCAGCAATTTTGATT
TTGACCGGCCATGGCTCGCTCGATAGCGCGATCGAAGGCATTCATTTGGGTGTGTTCGACTATATGCTCAAAACTTCTAG
CCCGCAAGATGTGCTGGCGCGAGTCAAGAGTGCGCTTGAGGCTCAAGCCGATCAACGGCATAAAAAAAGCCTCATGAATA
CGCTACAAACGGTGGTTAGCGAGCTTGGTGGCAAACAACAAGAGCCAAGCGAAACCCCAACTCAACAGCCAGCTGGCGAT
CAATGGATTCGCGTCGGTGAGCTAGAAATTGGCTTATGGCGACAAATGGCGCGGCTTGGCGACCAAACCCTGAATCTCAC
GCCAACCGAATTTCGTTTGTTGAGTTGTTTGGCTCAGCAAGCAGGATTGGTGATGAGCTACGCCAATTTGTTACGTTGTG
CCCAAGGCTACGAGGCCGAAAGCAGCGAAGCCGCCGAATTGCTCAAACCGCATATCTACCACTTGCGCCAAAAGATCGAG
CCAGATCCATCAAATCCACGCTATATTTTGACCGTGCGTGGCACTGGCTATGTCTTGGCAGTCGAAGCACCCCAAAGTAA
GTAA

Upstream 100 bases:

>100_bases
GACCCAGCATGGTGGCCAAATCGAGGTTGACAGCACCGTTGGGGTTGGCTCGACCTTCCGTGTTGTGCTACCCTACCAAC
CTAACTAGGAGTATTCTTCG

Downstream 100 bases:

>100_bases
TCAAGCCAGCGCCCAAGCCTTGAAACTTGGGCGCATTGTTTATTGCCCAATTTGCTGCAAAACCTTTTCCTCAAATTTAT
CGCCAATAATGCTGCTCAAG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MSQASILLVDDEFPIRATLGDLLRRRGYDVQTADSGEEALDRIAQRPFDLFLLDLRLPGVDGITVAQRVRERYPDAAILI
LTGHGSLDSAIEGIHLGVFDYMLKTSSPQDVLARVKSALEAQADQRHKKSLMNTLQTVVSELGGKQQEPSETPTQQPAGD
QWIRVGELEIGLWRQMARLGDQTLNLTPTEFRLLSCLAQQAGLVMSYANLLRCAQGYEAESSEAAELLKPHIYHLRQKIE
PDPSNPRYILTVRGTGYVLAVEAPQSK

Sequences:

>Translated_267_residues
MSQASILLVDDEFPIRATLGDLLRRRGYDVQTADSGEEALDRIAQRPFDLFLLDLRLPGVDGITVAQRVRERYPDAAILI
LTGHGSLDSAIEGIHLGVFDYMLKTSSPQDVLARVKSALEAQADQRHKKSLMNTLQTVVSELGGKQQEPSETPTQQPAGD
QWIRVGELEIGLWRQMARLGDQTLNLTPTEFRLLSCLAQQAGLVMSYANLLRCAQGYEAESSEAAELLKPHIYHLRQKIE
PDPSNPRYILTVRGTGYVLAVEAPQSK
>Mature_266_residues
SQASILLVDDEFPIRATLGDLLRRRGYDVQTADSGEEALDRIAQRPFDLFLLDLRLPGVDGITVAQRVRERYPDAAILIL
TGHGSLDSAIEGIHLGVFDYMLKTSSPQDVLARVKSALEAQADQRHKKSLMNTLQTVVSELGGKQQEPSETPTQQPAGDQ
WIRVGELEIGLWRQMARLGDQTLNLTPTEFRLLSCLAQQAGLVMSYANLLRCAQGYEAESSEAAELLKPHIYHLRQKIEP
DPSNPRYILTVRGTGYVLAVEAPQSK

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=258, Percent_Identity=32.5581395348837, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1788394, Length=258, Percent_Identity=32.5581395348837, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1786911, Length=253, Percent_Identity=28.8537549407115, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1790863, Length=264, Percent_Identity=28.4090909090909, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789402, Length=256, Percent_Identity=27.34375, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786599, Length=254, Percent_Identity=27.9527559055118, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI145693140, Length=259, Percent_Identity=27.4131274131274, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1790299, Length=131, Percent_Identity=29.7709923664122, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=35.0877192982456, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790860, Length=262, Percent_Identity=29.0076335877863, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI2367329, Length=256, Percent_Identity=28.515625, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1786784, Length=258, Percent_Identity=27.1317829457364, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788550, Length=132, Percent_Identity=28.7878787878788, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI87082012, Length=252, Percent_Identity=25.3968253968254, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1788905, Length=132, Percent_Identity=32.5757575757576, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787229, Length=258, Percent_Identity=24.8062015503876, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 29619; Mature: 29488

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQASILLVDDEFPIRATLGDLLRRRGYDVQTADSGEEALDRIAQRPFDLFLLDLRLPGV
CCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHEEEEEEECCCC
DGITVAQRVRERYPDAAILILTGHGSLDSAIEGIHLGVFDYMLKTSSPQDVLARVKSALE
CCHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
AQADQRHKKSLMNTLQTVVSELGGKQQEPSETPTQQPAGDQWIRVGELEIGLWRQMARLG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHC
DQTLNLTPTEFRLLSCLAQQAGLVMSYANLLRCAQGYEAESSEAAELLKPHIYHLRQKIE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCC
PDPSNPRYILTVRGTGYVLAVEAPQSK
CCCCCCEEEEEECCCCEEEEEECCCCC
>Mature Secondary Structure 
SQASILLVDDEFPIRATLGDLLRRRGYDVQTADSGEEALDRIAQRPFDLFLLDLRLPGV
CCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHEEEEEEECCCC
DGITVAQRVRERYPDAAILILTGHGSLDSAIEGIHLGVFDYMLKTSSPQDVLARVKSALE
CCHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
AQADQRHKKSLMNTLQTVVSELGGKQQEPSETPTQQPAGDQWIRVGELEIGLWRQMARLG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHC
DQTLNLTPTEFRLLSCLAQQAGLVMSYANLLRCAQGYEAESSEAAELLKPHIYHLRQKIE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCC
PDPSNPRYILTVRGTGYVLAVEAPQSK
CCCCCCEEEEEECCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]