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The map label for this gene is tpiA [H]

Identifier: 158423834

GI number: 158423834

Start: 2525601

End: 2526362

Strand: Direct

Name: tpiA [H]

Synonym: AZC_2210

Alternate gene names: 158423834

Gene position: 2525601-2526362 (Clockwise)

Preceding gene: 158423824

Following gene: 158423835

Centisome position: 47.03

GC content: 71.0

Gene sequence:

>762_bases
ATGATGATGTCCGCCGAACGCCGCCCCCTCGTTGCCGGAAATTGGAAGATGAACGGGCTGAAGGCGTCCACGGCGGAAAT
CGGCGCGATCGCGGCCGGTTATAATGCGGCCCTTGCGGGCAAGATCGATCTGCTCCTGTGCCCGCCCGCCACCGTGCTGG
CGCAGGCCGCGACCCTCGCGGACGGCCGTATCCTTGTGGGCGGTCAGGACTGCCACGCCAAGGCGAGCGGCGCCCATACC
GGCGACATCTCCGCCGAGATGCTGGCGGATGCCGGCGCCAAGGCGGTGATCGTCGGCCATTCCGAGCGCCGGGCCGACCA
CCACGAGAGCGATGCCGATGTCCGGGCCAAGGCGGAAGCCGCTTGGCGCGCCGGGCTCGTGGCCGTCATCTGCGTCGGCG
AGAGCGAGGCTCAGCGTCGGGCGGGCGAGCACGGCGCGGTCGTGGCGGCTCAGGTGCGCGGCTCGGTGCCGGATGGCGCG
ACGTCGTCCAATACGGTTGTCGCCTACGAGCCCATCTGGGCCATCGGCACCGGCCTCGTGCCGACGCCGGCCGATGTGGC
GGAAGTCCACGGCATTGTCCGCTCCGTGCTGGCCGAGCGCTTCGGCGCGGCGGCGGGCGGCATGCGCATCCTCTATGGCG
GCTCCGTGAAGCCTGAGAACGCCAAGGCTCTGCTGGGCGCGGCCGATGTGGACGGCGCCCTCGTCGGCGGCGCCAGCCTC
AAGGCGGCGGACTTTCTCGCCATCGCGCGCACCTATCTCTGA

Upstream 100 bases:

>100_bases
CGCCGCAACGGCGCTCGCGCCCCCTGCTACCAGCCTTTTTGCGGTCACGGTTTGCGGCTTCCGGCCGGCTCTGCTAACGG
GGCGGCACCGCAAGCTGGAG

Downstream 100 bases:

>100_bases
GGGCCGGGCCGCATGCGCGGCCTTCATGATTTCCCGGATCCGAGGTCGGCATGAGCGGTGAGGGGCAGGAACGGGTTCGG
CTGGCCTTGCCGGCCGCCTA

Product: triosephosphate isomerase

Products: NA

Alternate protein names: TIM; Triose-phosphate isomerase [H]

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MMMSAERRPLVAGNWKMNGLKASTAEIGAIAAGYNAALAGKIDLLLCPPATVLAQAATLADGRILVGGQDCHAKASGAHT
GDISAEMLADAGAKAVIVGHSERRADHHESDADVRAKAEAAWRAGLVAVICVGESEAQRRAGEHGAVVAAQVRGSVPDGA
TSSNTVVAYEPIWAIGTGLVPTPADVAEVHGIVRSVLAERFGAAAGGMRILYGGSVKPENAKALLGAADVDGALVGGASL
KAADFLAIARTYL

Sequences:

>Translated_253_residues
MMMSAERRPLVAGNWKMNGLKASTAEIGAIAAGYNAALAGKIDLLLCPPATVLAQAATLADGRILVGGQDCHAKASGAHT
GDISAEMLADAGAKAVIVGHSERRADHHESDADVRAKAEAAWRAGLVAVICVGESEAQRRAGEHGAVVAAQVRGSVPDGA
TSSNTVVAYEPIWAIGTGLVPTPADVAEVHGIVRSVLAERFGAAAGGMRILYGGSVKPENAKALLGAADVDGALVGGASL
KAADFLAIARTYL
>Mature_253_residues
MMMSAERRPLVAGNWKMNGLKASTAEIGAIAAGYNAALAGKIDLLLCPPATVLAQAATLADGRILVGGQDCHAKASGAHT
GDISAEMLADAGAKAVIVGHSERRADHHESDADVRAKAEAAWRAGLVAVICVGESEAQRRAGEHGAVVAAQVRGSVPDGA
TSSNTVVAYEPIWAIGTGLVPTPADVAEVHGIVRSVLAERFGAAAGGMRILYGGSVKPENAKALLGAADVDGALVGGASL
KAADFLAIARTYL

Specific function: Plays an important role in several metabolic pathways. [C]

COG id: COG0149

COG function: function code G; Triosephosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the triosephosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI226529917, Length=248, Percent_Identity=41.1290322580645, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI4507645, Length=248, Percent_Identity=41.1290322580645, Blast_Score=159, Evalue=2e-39,
Organism=Escherichia coli, GI1790353, Length=247, Percent_Identity=41.7004048582996, Blast_Score=169, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17536593, Length=244, Percent_Identity=43.4426229508197, Blast_Score=174, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6320255, Length=247, Percent_Identity=42.1052631578947, Blast_Score=189, Evalue=4e-49,
Organism=Drosophila melanogaster, GI28572004, Length=243, Percent_Identity=44.4444444444444, Blast_Score=176, Evalue=1e-44,
Organism=Drosophila melanogaster, GI28572008, Length=243, Percent_Identity=44.4444444444444, Blast_Score=176, Evalue=1e-44,
Organism=Drosophila melanogaster, GI28572006, Length=243, Percent_Identity=44.4444444444444, Blast_Score=176, Evalue=1e-44,

Paralogues:

None

Copy number: 1120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022896
- InterPro:   IPR000652
- InterPro:   IPR020861 [H]

Pfam domain/function: PF00121 TIM [H]

EC number: =5.3.1.1 [H]

Molecular weight: Translated: 25519; Mature: 25519

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00171 TIM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMMSAERRPLVAGNWKMNGLKASTAEIGAIAAGYNAALAGKIDLLLCPPATVLAQAATLA
CCCCCCCCCEEECCEEECCEECCCHHHHEEECCCCEEEECCEEEEECCCHHHHHHHHHCC
DGRILVGGQDCHAKASGAHTGDISAEMLADAGAKAVIVGHSERRADHHESDADVRAKAEA
CCEEEECCCCCCCCCCCCCCCCCHHHHHHCCCCEEEEEECCHHCCCCCCCCCCHHHHHHH
AWRAGLVAVICVGESEAQRRAGEHGAVVAAQVRGSVPDGATSSNTVVAYEPIWAIGTGLV
HHHCCEEEEEEECCCHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEEEECCHHHHCCCCC
PTPADVAEVHGIVRSVLAERFGAAAGGMRILYGGSVKPENAKALLGAADVDGALVGGASL
CCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEECCCCCCEEECCCCC
KAADFLAIARTYL
CHHHHHHHHHHCC
>Mature Secondary Structure
MMMSAERRPLVAGNWKMNGLKASTAEIGAIAAGYNAALAGKIDLLLCPPATVLAQAATLA
CCCCCCCCCEEECCEEECCEECCCHHHHEEECCCCEEEECCEEEEECCCHHHHHHHHHCC
DGRILVGGQDCHAKASGAHTGDISAEMLADAGAKAVIVGHSERRADHHESDADVRAKAEA
CCEEEECCCCCCCCCCCCCCCCCHHHHHHCCCCEEEEEECCHHCCCCCCCCCCHHHHHHH
AWRAGLVAVICVGESEAQRRAGEHGAVVAAQVRGSVPDGATSSNTVVAYEPIWAIGTGLV
HHHCCEEEEEEECCCHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEEEECCHHHHCCCCC
PTPADVAEVHGIVRSVLAERFGAAAGGMRILYGGSVKPENAKALLGAADVDGALVGGASL
CCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEECCCCCCEEECCCCC
KAADFLAIARTYL
CHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA