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The map label for this gene is lacY [H]

Identifier: 158423835

GI number: 158423835

Start: 2526413

End: 2527576

Strand: Direct

Name: lacY [H]

Synonym: AZC_2211

Alternate gene names: 158423835

Gene position: 2526413-2527576 (Clockwise)

Preceding gene: 158423834

Following gene: 158423837

Centisome position: 47.05

GC content: 69.93

Gene sequence:

>1164_bases
ATGAGCGGTGAGGGGCAGGAACGGGTTCGGCTGGCCTTGCCGGCCGCCTATGCGGGCCTGTTCTTCGCCCTCGGCGTCTA
CATGCCCTTCTTCCCGCTCTGGCTCGGGGAACGCGGGCTCTCGCCCGGCGAGATCGGCACCGCCCTGGCCGTTCCGCTGA
CCACCCGCCTTCTCGCGACGCCAATACTGGGTTGGCTTTCCGATCGCATCGGCAAGCCGCGCGCGGTCCTGCTGCTGCTT
GCGGCACTGACGCTGCTGGTGATGAGCGCGCTGGTTCTCGCCTCCGGCGCGGTGGCGATCTTCCTCATCCTCGGCCTTGC
CGCCATGGCGTGGAACCCGTCCTTTCCGCTGCTGGACGCCTATGCGAGCCGGCAGGCGCGGGCGAAGCGCGTGGATTATG
GCCGCAGCCGCATGTGGGGCTCGGCCTCCTTCATCCTCGCCAATCTTCTCGGTGGATGGCTCGTGGGTGCGGCGGGCGCG
GGCGTCACCGTGCCGCTCATGCTCGCGGGGCACGCGGCCTTCCTGCTCACCTTGGTGATGCTGCCAGAGATGCCCCGCCC
GCCTGCTGCGGCGGGGCTTCACGTCAGCGTGCCGCGGGCGCGGACGGCGCTCGTCATCGGCATTCTGGCGGCGGCCAGCG
TGCAGGCGAGCCATGCGGTGCTCTATGCCTTCGGCTCCGTCACCTGGCAGAAGCAGGGCCTGTCGCTCGGCACCATCGGG
ATGCTCTGGGCTCTTGGCGTCGTCTCGGAAATCGTGCTGTTCCACTTCGGCACGCGGGTGCTGCGGCGCCTGCCGCCGGC
TCTGTTGCTGGCCATCGGCGGTGCGGCGGCAATGGTGCGCTTCGGGGCGATGACGTTCGATCTGCCGCTGGCGCTTCTGC
TGCCGCTGCAACTGCTGCATGGCGCGACCTTTGGCGCCACCTATCTTGGCCTCGTGGAACTGGTGGCCCGCGCCGTGCCC
GAGCATCGGGCGGCAACCGTTCAGTCCCTGGCCGGCTGGACGGTGAGCCTTGCCATGGCGGCAGCGAGCGTCGCGTCAGG
GCCGCTCTTCCAGGCCTTCGGGGCGAACGCATTTTATCTCTCTGTGGCGCTCGGTGCTGTGGGCCTGGTGGCGGCGCTTG
CCTCCGCCGCGCTTCAGCCCCAGAGGTCGGGCGTCGGGGGGTAG

Upstream 100 bases:

>100_bases
CCAGCCTCAAGGCGGCGGACTTTCTCGCCATCGCGCGCACCTATCTCTGAGGGCCGGGCCGCATGCGCGGCCTTCATGAT
TTCCCGGATCCGAGGTCGGC

Downstream 100 bases:

>100_bases
GCGAGGGCGCCGTCGTATCGGATGCCCGGCTGCCGGTCGCGGGCGAGCAGCAGAGGCCCGTCGAGGTCCACCACCTGCGC
CTTCTGGGCCAACAGGAGAG

Product: proton/sugar symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MSGEGQERVRLALPAAYAGLFFALGVYMPFFPLWLGERGLSPGEIGTALAVPLTTRLLATPILGWLSDRIGKPRAVLLLL
AALTLLVMSALVLASGAVAIFLILGLAAMAWNPSFPLLDAYASRQARAKRVDYGRSRMWGSASFILANLLGGWLVGAAGA
GVTVPLMLAGHAAFLLTLVMLPEMPRPPAAAGLHVSVPRARTALVIGILAAASVQASHAVLYAFGSVTWQKQGLSLGTIG
MLWALGVVSEIVLFHFGTRVLRRLPPALLLAIGGAAAMVRFGAMTFDLPLALLLPLQLLHGATFGATYLGLVELVARAVP
EHRAATVQSLAGWTVSLAMAAASVASGPLFQAFGANAFYLSVALGAVGLVAALASAALQPQRSGVGG

Sequences:

>Translated_387_residues
MSGEGQERVRLALPAAYAGLFFALGVYMPFFPLWLGERGLSPGEIGTALAVPLTTRLLATPILGWLSDRIGKPRAVLLLL
AALTLLVMSALVLASGAVAIFLILGLAAMAWNPSFPLLDAYASRQARAKRVDYGRSRMWGSASFILANLLGGWLVGAAGA
GVTVPLMLAGHAAFLLTLVMLPEMPRPPAAAGLHVSVPRARTALVIGILAAASVQASHAVLYAFGSVTWQKQGLSLGTIG
MLWALGVVSEIVLFHFGTRVLRRLPPALLLAIGGAAAMVRFGAMTFDLPLALLLPLQLLHGATFGATYLGLVELVARAVP
EHRAATVQSLAGWTVSLAMAAASVASGPLFQAFGANAFYLSVALGAVGLVAALASAALQPQRSGVGG
>Mature_386_residues
SGEGQERVRLALPAAYAGLFFALGVYMPFFPLWLGERGLSPGEIGTALAVPLTTRLLATPILGWLSDRIGKPRAVLLLLA
ALTLLVMSALVLASGAVAIFLILGLAAMAWNPSFPLLDAYASRQARAKRVDYGRSRMWGSASFILANLLGGWLVGAAGAG
VTVPLMLAGHAAFLLTLVMLPEMPRPPAAAGLHVSVPRARTALVIGILAAASVQASHAVLYAFGSVTWQKQGLSLGTIGM
LWALGVVSEIVLFHFGTRVLRRLPPALLLAIGGAAAMVRFGAMTFDLPLALLLPLQLLHGATFGATYLGLVELVARAVPE
HRAATVQSLAGWTVSLAMAAASVASGPLFQAFGANAFYLSVALGAVGLVAALASAALQPQRSGVGG

Specific function: Probable permease involved in the uptake of 3- phenylpropionic acid [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacY/rafB permease family. HcaT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788886, Length=355, Percent_Identity=29.5774647887324, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1786538, Length=386, Percent_Identity=22.279792746114, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022814
- InterPro:   IPR016196
- InterPro:   IPR005276 [H]

Pfam domain/function: PF01306 LacY_symp [H]

EC number: NA

Molecular weight: Translated: 39968; Mature: 39837

Theoretical pI: Translated: 11.47; Mature: 11.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGEGQERVRLALPAAYAGLFFALGVYMPFFPLWLGERGLSPGEIGTALAVPLTTRLLAT
CCCCCCHHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCHHHHHHHHHHHHHH
PILGWLSDRIGKPRAVLLLLAALTLLVMSALVLASGAVAIFLILGLAAMAWNPSFPLLDA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
YASRQARAKRVDYGRSRMWGSASFILANLLGGWLVGAAGAGVTVPLMLAGHAAFLLTLVM
HHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
LPEMPRPPAAAGLHVSVPRARTALVIGILAAASVQASHAVLYAFGSVTWQKQGLSLGTIG
CCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHH
MLWALGVVSEIVLFHFGTRVLRRLPPALLLAIGGAAAMVRFGAMTFDLPLALLLPLQLLH
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCHHHHHHHHCCHHHHHHHHHHHHHHHHH
GATFGATYLGLVELVARAVPEHRAATVQSLAGWTVSLAMAAASVASGPLFQAFGANAFYL
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHH
SVALGAVGLVAALASAALQPQRSGVGG
HHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SGEGQERVRLALPAAYAGLFFALGVYMPFFPLWLGERGLSPGEIGTALAVPLTTRLLAT
CCCCCHHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCHHHHHHHHHHHHHH
PILGWLSDRIGKPRAVLLLLAALTLLVMSALVLASGAVAIFLILGLAAMAWNPSFPLLDA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
YASRQARAKRVDYGRSRMWGSASFILANLLGGWLVGAAGAGVTVPLMLAGHAAFLLTLVM
HHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
LPEMPRPPAAAGLHVSVPRARTALVIGILAAASVQASHAVLYAFGSVTWQKQGLSLGTIG
CCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHH
MLWALGVVSEIVLFHFGTRVLRRLPPALLLAIGGAAAMVRFGAMTFDLPLALLLPLQLLH
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCHHHHHHHHCCHHHHHHHHHHHHHHHHH
GATFGATYLGLVELVARAVPEHRAATVQSLAGWTVSLAMAAASVASGPLFQAFGANAFYL
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHH
SVALGAVGLVAALASAALQPQRSGVGG
HHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9603882; 9205837; 9278503 [H]