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The map label for this gene is arsR [H]

Identifier: 158423710

GI number: 158423710

Start: 2399232

End: 2399573

Strand: Direct

Name: arsR [H]

Synonym: AZC_2086

Alternate gene names: 158423710

Gene position: 2399232-2399573 (Clockwise)

Preceding gene: 158423697

Following gene: 158423711

Centisome position: 44.68

GC content: 65.5

Gene sequence:

>342_bases
ATGTCAACGAGCAAAAATGCCGCGCCGTCGACCCCGGGCGTCGTGGCGCTGGAAGCCAAAGCGGAGGAAGTGGCGGCGCT
GCTGTCCTCCATGGCCAATGCCAAGCGTCTGCTGGTGCTGTGCCAGCTTGTGGAGGGCGAGCGTTCGGTGGGCGACCTTG
CCGAGGTGGTGGGTCTCAGCCAGTCCGCGCTCTCGCAGCATCTCGCGAAGATGCGCCTGCAAGGGCTCGTGGAGACCCGG
CGGGAAGCACAGACGGTCTATTACCGGCTGGCCAGCGGCGAGGTGCGGCAACTCCTCGAAACGCTCCATGGCATTTTTTG
CGGCGACCTTGCGCCCGCTTGA

Upstream 100 bases:

>100_bases
ATGCCGACTGCCACGCGGATGGCACGATCCAGGGAACCGACGTTGACCATGGGACTCTCCATGTGTAAATTAGAAGATAC
GAATATTAGGTTATTCTAAA

Downstream 100 bases:

>100_bases
ACCGCCATGGGGCGGCCGGCCGGAATGGTCCTTTGGCGGGGGTTGCGCTCGCGCGAAAAAAGGTGAATTAAGCTGACCTA
ATCGCCGCAGTATTCTGTCA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 113; Mature: 112

Protein sequence:

>113_residues
MSTSKNAAPSTPGVVALEAKAEEVAALLSSMANAKRLLVLCQLVEGERSVGDLAEVVGLSQSALSQHLAKMRLQGLVETR
REAQTVYYRLASGEVRQLLETLHGIFCGDLAPA

Sequences:

>Translated_113_residues
MSTSKNAAPSTPGVVALEAKAEEVAALLSSMANAKRLLVLCQLVEGERSVGDLAEVVGLSQSALSQHLAKMRLQGLVETR
REAQTVYYRLASGEVRQLLETLHGIFCGDLAPA
>Mature_112_residues
STSKNAAPSTPGVVALEAKAEEVAALLSSMANAKRLLVLCQLVEGERSVGDLAEVVGLSQSALSQHLAKMRLQGLVETRR
EAQTVYYRLASGEVRQLLETLHGIFCGDLAPA

Specific function: Up-regulates the expression of the hemolysin gene, hlyA, and may promote expression of other virulence determinants in vivo. It may have both positive and negative regulator activities [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789021, Length=92, Percent_Identity=44.5652173913043, Blast_Score=84, Evalue=3e-18,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 11992; Mature: 11861

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSKNAAPSTPGVVALEAKAEEVAALLSSMANAKRLLVLCQLVEGERSVGDLAEVVGLS
CCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
QSALSQHLAKMRLQGLVETRREAQTVYYRLASGEVRQLLETLHGIFCGDLAPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
STSKNAAPSTPGVVALEAKAEEVAALLSSMANAKRLLVLCQLVEGERSVGDLAEVVGLS
CCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
QSALSQHLAKMRLQGLVETRREAQTVYYRLASGEVRQLLETLHGIFCGDLAPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8231807; 9457888; 10952301 [H]