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The map label for this gene is thrB

Identifier: 158423091

GI number: 158423091

Start: 1665920

End: 1666885

Strand: Reverse

Name: thrB

Synonym: AZC_1467

Alternate gene names: 158423091

Gene position: 1666885-1665920 (Counterclockwise)

Preceding gene: 158423092

Following gene: 158423090

Centisome position: 31.04

GC content: 66.56

Gene sequence:

>966_bases
GTGGCGGTCTATACGGACGTTTCGGCGGCGAGCCTTTCGGATTATCTCGCCGCTTACGATATCGGCACACTGGTTTCGTA
TCACGGCATCGCGGAGGGCGTGGAGAATTCCAACTTCCTCGTCCAGACCACGACCGCGAGCTTCATCCTCACGCTCTATG
AGAAGCGCGTCGATCCGGCCGACCTGCCCTTCTTCATCGGCCTGATGCAGCATCTGGCGGCGAACGGCATTTCGTGCCCG
CAGCCGGTGGCCATGCGCGACGGCACCATGCTCGGCACCCTTGCCGGCCGCCCCTGCGCCATCGTGACCTTCCTTCCCGG
CGTGTCCGTGCGCAAGCCCACCGCCGCCAACTGCGGACAGCTCGGACGCGCGCTGGCGCAACTGCATCTTGCGGGTGCGG
GCTTCGAGATCACTCGCCGCAATGCCCTTTCCGTGTCCGGCTGGCGGCCTTTGTTCGAGGCGGCAGGCCCGCGCACCGAT
ACGGTCCATCCCGGCCTTGCGGCGATCATCACCGAGGAACTGGCCGCGCACGAGGCCCACTGGCCCGCCGCGCTTCCGGC
CGGTGTGATCCATGCGGATCTCTTCCCGGACAACGCCTTCTTCCTCGATGACACCCTCTCCGGCATCATCGACTTCTACT
TCGCCTGCAACGATCTCTTTGCTTATGACGTGGCCGTGTGCCTGAACGCCTGGTGCTTCGAGGCGGACGGCGCCTTCAAC
GCCACCAAGGGTCGGGCGCTGCTCGCCGGCTACCAGGCGGTGCGCCCGATGGAAGCGGCTGAGGTGGAGGCCCTGCCCCA
GCTCGCCCGCGGCGCCGCCCTGCGCTTCCTGCTCACGCGGCTGGTGGACTGGCTGAACGTGCCGGAAGGCGCCCTCGTGC
GCCCCAAAGACCCCTTGGAATATCTGAGGAAGCTACGCTTCCACCGGGCCGTAGCCAGCGCCCGCGACTATGGACTTGCC
GCATGA

Upstream 100 bases:

>100_bases
CGAGCGTTACGACGTGGATGTGGAAACGGTGACGGCCGCGCAGGAGGATGTGTTCTTTCCGCTTCCCCGCGCGCTGCGCG
AAGATGCGGCGGAGTAGAGC

Downstream 100 bases:

>100_bases
GCCGGGTGGAGATCTGGACCGACGGCGCCTGCTCGGGCAATCCCGGCCCCGGCGGCTGGGGCGCCATCCTGCGCTCCGGT
CCGCACGAGAAGGAACTGAA

Product: homoserine kinase

Products: NA

Alternate protein names: HK; HSK

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MAVYTDVSAASLSDYLAAYDIGTLVSYHGIAEGVENSNFLVQTTTASFILTLYEKRVDPADLPFFIGLMQHLAANGISCP
QPVAMRDGTMLGTLAGRPCAIVTFLPGVSVRKPTAANCGQLGRALAQLHLAGAGFEITRRNALSVSGWRPLFEAAGPRTD
TVHPGLAAIITEELAAHEAHWPAALPAGVIHADLFPDNAFFLDDTLSGIIDFYFACNDLFAYDVAVCLNAWCFEADGAFN
ATKGRALLAGYQAVRPMEAAEVEALPQLARGAALRFLLTRLVDWLNVPEGALVRPKDPLEYLRKLRFHRAVASARDYGLA
A

Sequences:

>Translated_321_residues
MAVYTDVSAASLSDYLAAYDIGTLVSYHGIAEGVENSNFLVQTTTASFILTLYEKRVDPADLPFFIGLMQHLAANGISCP
QPVAMRDGTMLGTLAGRPCAIVTFLPGVSVRKPTAANCGQLGRALAQLHLAGAGFEITRRNALSVSGWRPLFEAAGPRTD
TVHPGLAAIITEELAAHEAHWPAALPAGVIHADLFPDNAFFLDDTLSGIIDFYFACNDLFAYDVAVCLNAWCFEADGAFN
ATKGRALLAGYQAVRPMEAAEVEALPQLARGAALRFLLTRLVDWLNVPEGALVRPKDPLEYLRKLRFHRAVASARDYGLA
A
>Mature_320_residues
AVYTDVSAASLSDYLAAYDIGTLVSYHGIAEGVENSNFLVQTTTASFILTLYEKRVDPADLPFFIGLMQHLAANGISCPQ
PVAMRDGTMLGTLAGRPCAIVTFLPGVSVRKPTAANCGQLGRALAQLHLAGAGFEITRRNALSVSGWRPLFEAAGPRTDT
VHPGLAAIITEELAAHEAHWPAALPAGVIHADLFPDNAFFLDDTLSGIIDFYFACNDLFAYDVAVCLNAWCFEADGAFNA
TKGRALLAGYQAVRPMEAAEVEALPQLARGAALRFLLTRLVDWLNVPEGALVRPKDPLEYLRKLRFHRAVASARDYGLAA

Specific function: Unknown

COG id: COG2334

COG function: function code R; Putative homoserine kinase type II (protein kinase fold)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pseudomonas-type thrB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KHSE_AZOC5 (A8HX69)

Other databases:

- EMBL:   AP009384
- RefSeq:   YP_001524383.1
- ProteinModelPortal:   A8HX69
- SMR:   A8HX69
- GeneID:   5688245
- GenomeReviews:   AP009384_GR
- KEGG:   azc:AZC_1467
- HOGENOM:   HBG309377
- OMA:   ADLFRDN
- ProtClustDB:   PRK05231
- BioCyc:   ACAU438753:AZC_1467-MONOMER
- HAMAP:   MF_00301
- InterPro:   IPR002575
- InterPro:   IPR005280
- InterPro:   IPR011009
- TIGRFAMs:   TIGR00938

Pfam domain/function: PF01636 APH; SSF56112 Kinase_like

EC number: =2.7.1.39

Molecular weight: Translated: 34480; Mature: 34349

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVYTDVSAASLSDYLAAYDIGTLVSYHGIAEGVENSNFLVQTTTASFILTLYEKRVDPA
CCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHCCCCC
DLPFFIGLMQHLAANGISCPQPVAMRDGTMLGTLAGRPCAIVTFLPGVSVRKPTAANCGQ
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCEEEEEECCCCCCCCCCCCCHHH
LGRALAQLHLAGAGFEITRRNALSVSGWRPLFEAAGPRTDTVHPGLAAIITEELAAHEAH
HHHHHHHHHHCCCCEEEECCCCEECCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCC
WPAALPAGVIHADLFPDNAFFLDDTLSGIIDFYFACNDLFAYDVAVCLNAWCFEADGAFN
CCCCCCCCCEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCC
ATKGRALLAGYQAVRPMEAAEVEALPQLARGAALRFLLTRLVDWLNVPEGALVRPKDPLE
CCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHH
YLRKLRFHRAVASARDYGLAA
HHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AVYTDVSAASLSDYLAAYDIGTLVSYHGIAEGVENSNFLVQTTTASFILTLYEKRVDPA
CEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHCCCCC
DLPFFIGLMQHLAANGISCPQPVAMRDGTMLGTLAGRPCAIVTFLPGVSVRKPTAANCGQ
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCEEEEEECCCCCCCCCCCCCHHH
LGRALAQLHLAGAGFEITRRNALSVSGWRPLFEAAGPRTDTVHPGLAAIITEELAAHEAH
HHHHHHHHHHCCCCEEEECCCCEECCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCC
WPAALPAGVIHADLFPDNAFFLDDTLSGIIDFYFACNDLFAYDVAVCLNAWCFEADGAFN
CCCCCCCCCEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCC
ATKGRALLAGYQAVRPMEAAEVEALPQLARGAALRFLLTRLVDWLNVPEGALVRPKDPLE
CCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHH
YLRKLRFHRAVASARDYGLAA
HHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA