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The map label for this gene is ispH [H]

Identifier: 158423092

GI number: 158423092

Start: 1666889

End: 1667854

Strand: Reverse

Name: ispH [H]

Synonym: AZC_1468

Alternate gene names: 158423092

Gene position: 1667854-1666889 (Counterclockwise)

Preceding gene: 158423093

Following gene: 158423091

Centisome position: 31.06

GC content: 68.12

Gene sequence:

>966_bases
ATGTCCGCTGAAAAGCCCCCTCTCCGCATCCTGCTCTGCGCGCCGCGCGGCTTCTGCGCCGGCGTGGTGCGGGCCATTGA
CGCGGTGGAGCGCGCACTCGCGCTGCACGGTGCACCGGTCTATGTGCGGCATGAGATCGTTCACAACAAATATGTGGTGG
ACGGCCTGCGCAAGAAGGGCGCCGTCTTCGTGGAGGAACTGGACGAGGTGCCGCCCGGCGATGCCCCCGTCATCTTCTCC
GCGCACGGCGTGCCCAGGTCCGTGCCCGAGGCAGCGGCCGCCCGCAACCTCTTCGCCATCGACGCCACCTGCCCGCTGGT
GACCAAGGTCCATCGCGAGGCGCAGTTGCACCACAAGAAGGGCCGGCACGTGCTGCTCATCGGCCATGCCCGCCATCCGG
AAGTGGTCGGCACCATGGGCCAGTTGCCCGAGGGCGCAGTGACGCTGATCGAAACGGCGCAGGATGCCCGCACCATCGCG
CCGGCCGACCCCGAGAATCTCGCCTATGCGACGCAGACGACCCTGTCGCTGGACGACACGGCGGAGATTGTCGCCATCCT
CCGCGCGCGCTTCCCCACCATCGCCGTGCCGCACAAGGAAGACATCTGCTACGCCACCACCAACCGCCAGGAAGCGGTGA
AGAAGGTGGCGCCGCAGGTGGACGCCATGGTGGTGGTGGGCGCGCCCAACTCCTCCAATTCCCAGCGCCTGCGCGAAACC
GCCGAGCGCGAGGGCTGCGCCGTCTCGGTTCTGGTCCAGCGGGCGAGCGACCTCGACTGGTCGCGGCTGTCGGAGCTGAA
GAGCCTCGGCATCACCGCCGGGGCCTCGGCGCCCGAGGTGCTGGTGGAAGAAATCATCGACGCTTTTGCCGAGCGTTACG
ACGTGGATGTGGAAACGGTGACGGCCGCGCAGGAGGATGTGTTCTTTCCGCTTCCCCGCGCGCTGCGCGAAGATGCGGCG
GAGTAG

Upstream 100 bases:

>100_bases
CGCGCCTGAGGGGAGGCTGCCGGGGCCATCCCTGCCCGGGCGCCCGCTTGACAGGATGTGCCCTGCCATCCCATGTCCCC
GGTGAACACCGGGAACACCC

Downstream 100 bases:

>100_bases
AGCGTGGCGGTCTATACGGACGTTTCGGCGGCGAGCCTTTCGGATTATCTCGCCGCTTACGATATCGGCACACTGGTTTC
GTATCACGGCATCGCGGAGG

Product: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MSAEKPPLRILLCAPRGFCAGVVRAIDAVERALALHGAPVYVRHEIVHNKYVVDGLRKKGAVFVEELDEVPPGDAPVIFS
AHGVPRSVPEAAAARNLFAIDATCPLVTKVHREAQLHHKKGRHVLLIGHARHPEVVGTMGQLPEGAVTLIETAQDARTIA
PADPENLAYATQTTLSLDDTAEIVAILRARFPTIAVPHKEDICYATTNRQEAVKKVAPQVDAMVVVGAPNSSNSQRLRET
AEREGCAVSVLVQRASDLDWSRLSELKSLGITAGASAPEVLVEEIIDAFAERYDVDVETVTAAQEDVFFPLPRALREDAA
E

Sequences:

>Translated_321_residues
MSAEKPPLRILLCAPRGFCAGVVRAIDAVERALALHGAPVYVRHEIVHNKYVVDGLRKKGAVFVEELDEVPPGDAPVIFS
AHGVPRSVPEAAAARNLFAIDATCPLVTKVHREAQLHHKKGRHVLLIGHARHPEVVGTMGQLPEGAVTLIETAQDARTIA
PADPENLAYATQTTLSLDDTAEIVAILRARFPTIAVPHKEDICYATTNRQEAVKKVAPQVDAMVVVGAPNSSNSQRLRET
AEREGCAVSVLVQRASDLDWSRLSELKSLGITAGASAPEVLVEEIIDAFAERYDVDVETVTAAQEDVFFPLPRALREDAA
E
>Mature_320_residues
SAEKPPLRILLCAPRGFCAGVVRAIDAVERALALHGAPVYVRHEIVHNKYVVDGLRKKGAVFVEELDEVPPGDAPVIFSA
HGVPRSVPEAAAARNLFAIDATCPLVTKVHREAQLHHKKGRHVLLIGHARHPEVVGTMGQLPEGAVTLIETAQDARTIAP
ADPENLAYATQTTLSLDDTAEIVAILRARFPTIAVPHKEDICYATTNRQEAVKKVAPQVDAMVVVGAPNSSNSQRLRETA
EREGCAVSVLVQRASDLDWSRLSELKSLGITAGASAPEVLVEEIIDAFAERYDVDVETVTAAQEDVFFPLPRALREDAAE

Specific function: Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) [H]

COG id: COG0761

COG function: function code IM; Penicillin tolerance protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispH family [H]

Homologues:

Organism=Escherichia coli, GI1786212, Length=316, Percent_Identity=50.3164556962025, Blast_Score=318, Evalue=3e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003451 [H]

Pfam domain/function: PF02401 LYTB [H]

EC number: =1.17.1.2 [H]

Molecular weight: Translated: 34649; Mature: 34518

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAEKPPLRILLCAPRGFCAGVVRAIDAVERALALHGAPVYVRHEIVHNKYVVDGLRKKG
CCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCC
AVFVEELDEVPPGDAPVIFSAHGVPRSVPEAAAARNLFAIDATCPLVTKVHREAQLHHKK
CHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHC
GRHVLLIGHARHPEVVGTMGQLPEGAVTLIETAQDARTIAPADPENLAYATQTTLSLDDT
CCEEEEEECCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCHH
AEIVAILRARFPTIAVPHKEDICYATTNRQEAVKKVAPQVDAMVVVGAPNSSNSQRLRET
HHHHHHHHHCCCEEECCCCCCCEEEECCHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHH
AEREGCAVSVLVQRASDLDWSRLSELKSLGITAGASAPEVLVEEIIDAFAERYDVDVETV
HHHCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHH
TAAQEDVFFPLPRALREDAAE
HHCCCCCCCCCCHHHHHCCCC
>Mature Secondary Structure 
SAEKPPLRILLCAPRGFCAGVVRAIDAVERALALHGAPVYVRHEIVHNKYVVDGLRKKG
CCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCC
AVFVEELDEVPPGDAPVIFSAHGVPRSVPEAAAARNLFAIDATCPLVTKVHREAQLHHKK
CHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHC
GRHVLLIGHARHPEVVGTMGQLPEGAVTLIETAQDARTIAPADPENLAYATQTTLSLDDT
CCEEEEEECCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCHH
AEIVAILRARFPTIAVPHKEDICYATTNRQEAVKKVAPQVDAMVVVGAPNSSNSQRLRET
HHHHHHHHHCCCEEECCCCCCCEEEECCHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHH
AEREGCAVSVLVQRASDLDWSRLSELKSLGITAGASAPEVLVEEIIDAFAERYDVDVETV
HHHCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHH
TAAQEDVFFPLPRALREDAAE
HHCCCCCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA