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The map label for this gene is clpP [H]

Identifier: 158317029

GI number: 158317029

Start: 6343165

End: 6343809

Strand: Reverse

Name: clpP [H]

Synonym: Franean1_5273

Alternate gene names: 158317029

Gene position: 6343809-6343165 (Counterclockwise)

Preceding gene: 158317030

Following gene: 158317028

Centisome position: 70.63

GC content: 66.05

Gene sequence:

>645_bases
ATGCACGGACCACAGGGCTACTACGGAACGCAGAGCCGGTACGTCCTCCCCAACATCATCGAGAAGACGTCCCGCGGTGA
GTACGGGATGGACCCGTACTCGAAGCTGCTGAAGGAGCGCATCGTCTTCCTCGGCGCGCCGATCGATGACACGTCGGCGA
ACGACGTGATGGCGCAGCTGCTGTTCCTCGAGTCCGAGGACCCGGACCGCGACATCTCGATCTACATCAACTCGCCCGGT
GGGTCGTTCACGTCGCTGACCGCGATCTACGACACCATGCAGTTCGTGCGTCCCGACATCCAGACGATCTGCATGGGCCA
GGCGGCGTCCGCGGCGGCGGTGCTGCTCGCGGCCGGTACCCCCGGCAAGCGGTTCGCGCTGCAGAACAGCCGCATCCTCA
TCCACCAGCCGTCGGCGCAGGGCGAGGGCCAGTCCAGCGACATCGAGATCCAGGCGCGCGAGATCCTGCGCATGCGGTCG
CTGCTGGAGCACATGCTCGCCGAGCACACGGGGCGCACCGAGGAGGCCGTCCGCAAGGACATCGAGCGCGACAAGATCTT
CAGCGCCGACGAGGCCAAGGACTACGGCATCATCGACGAAGTGATCAAGACCCGGAAGTCCTCGCGGCTCGCCTCGGCGC
GCTGA

Upstream 100 bases:

>100_bases
GGGCCCGCCAGGTCCCCAGCGAAGGACCGGTGAGCTGACGCCCGCCGCGGCAGCGAGCCGTCCCGACCCTCGTCACCCGC
TCTCCTCGGAGGCAGTCACC

Downstream 100 bases:

>100_bases
GCCGGCGCCGAGTCGGCCCCGCCGGGCCCGGGCACGGCGGGGCTCACCGGGCCGGCCTCGGTGGGCGCCTCCGGGGCGCC
GCTTCCTCCGTCGGACCCGG

Product: ATP-dependent Clp protease proteolytic subunit

Products: NA

Alternate protein names: Endopeptidase Clp 2 [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MHGPQGYYGTQSRYVLPNIIEKTSRGEYGMDPYSKLLKERIVFLGAPIDDTSANDVMAQLLFLESEDPDRDISIYINSPG
GSFTSLTAIYDTMQFVRPDIQTICMGQAASAAAVLLAAGTPGKRFALQNSRILIHQPSAQGEGQSSDIEIQAREILRMRS
LLEHMLAEHTGRTEEAVRKDIERDKIFSADEAKDYGIIDEVIKTRKSSRLASAR

Sequences:

>Translated_214_residues
MHGPQGYYGTQSRYVLPNIIEKTSRGEYGMDPYSKLLKERIVFLGAPIDDTSANDVMAQLLFLESEDPDRDISIYINSPG
GSFTSLTAIYDTMQFVRPDIQTICMGQAASAAAVLLAAGTPGKRFALQNSRILIHQPSAQGEGQSSDIEIQAREILRMRS
LLEHMLAEHTGRTEEAVRKDIERDKIFSADEAKDYGIIDEVIKTRKSSRLASAR
>Mature_214_residues
MHGPQGYYGTQSRYVLPNIIEKTSRGEYGMDPYSKLLKERIVFLGAPIDDTSANDVMAQLLFLESEDPDRDISIYINSPG
GSFTSLTAIYDTMQFVRPDIQTICMGQAASAAAVLLAAGTPGKRFALQNSRILIHQPSAQGEGQSSDIEIQAREILRMRS
LLEHMLAEHTGRTEEAVRKDIERDKIFSADEAKDYGIIDEVIKTRKSSRLASAR

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Homo sapiens, GI5174419, Length=193, Percent_Identity=49.740932642487, Blast_Score=200, Evalue=8e-52,
Organism=Escherichia coli, GI1786641, Length=192, Percent_Identity=53.125, Blast_Score=230, Evalue=6e-62,
Organism=Caenorhabditis elegans, GI17538017, Length=192, Percent_Identity=45.3125, Blast_Score=179, Evalue=1e-45,
Organism=Drosophila melanogaster, GI20129427, Length=189, Percent_Identity=48.1481481481481, Blast_Score=192, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907
- InterPro:   IPR018215 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 23757; Mature: 23757

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS00381 CLP_PROTEASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHGPQGYYGTQSRYVLPNIIEKTSRGEYGMDPYSKLLKERIVFLGAPIDDTSANDVMAQL
CCCCCCCCCCCCCEECHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
LFLESEDPDRDISIYINSPGGSFTSLTAIYDTMQFVRPDIQTICMGQAASAAAVLLAAGT
HHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCHHHEEEEEECCC
PGKRFALQNSRILIHQPSAQGEGQSSDIEIQAREILRMRSLLEHMLAEHTGRTEEAVRKD
CCCEEEECCCEEEEECCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
IERDKIFSADEAKDYGIIDEVIKTRKSSRLASAR
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MHGPQGYYGTQSRYVLPNIIEKTSRGEYGMDPYSKLLKERIVFLGAPIDDTSANDVMAQL
CCCCCCCCCCCCCEECHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
LFLESEDPDRDISIYINSPGGSFTSLTAIYDTMQFVRPDIQTICMGQAASAAAVLLAAGT
HHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCHHHEEEEEECCC
PGKRFALQNSRILIHQPSAQGEGQSSDIEIQAREILRMRSLLEHMLAEHTGRTEEAVRKD
CCCEEEECCCEEEEECCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
IERDKIFSADEAKDYGIIDEVIKTRKSSRLASAR
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA