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The map label for this gene is clpP1 [H]

Identifier: 158317030

GI number: 158317030

Start: 6343872

End: 6344513

Strand: Reverse

Name: clpP1 [H]

Synonym: Franean1_5274

Alternate gene names: 158317030

Gene position: 6344513-6343872 (Counterclockwise)

Preceding gene: 158317031

Following gene: 158317029

Centisome position: 70.64

GC content: 67.76

Gene sequence:

>642_bases
GTGAGTGACATCGCCGCCCCTGGCCTGGCTGTCCCGGGCCCGAGTCTCCGCTCGCCGGGACAGAATGGCCCCGGCTTCGA
CGAGCAGGTCTTCAACCGTCTCCTCCGTGAGCGGATCATCTTCCTCGGTTCGGTGGTGGAGGACTCGATCGCCAACGCGA
TCTGCGCGCAGCTCCTGCTGCTGAACGCCGAGGACCCCGAGCGGGACATCTTCCTCTACATCAACTCGCCCGGCGGCTCG
GTCAGCGCCGGCATGGCGATCTACGACACCATGCAGTACGTCGAGAATGACGTCGCCACGGTTTCGCTGGGGCTCGCCGC
GTCGATGGGCCAGTTCCTGCTCTGCGCGGGCGCGCCGGGCAAGCGTTACTCGCTGCCGCACGCGCGGATCATGATGCACC
AGCCCTCCGGCGGCATCGGCGGAACGGCGTCCGACATCGCGATCCAGGCGGAGCAGATGCTCTACACCAAGCGGATGATG
CAGGAGCGCATCGCGTTCCACACCGGTCAGCCCGTCGAGCAGATCGAGCGGGACTCCGACCGCGACCGCTGGTTCACCGC
GGACGAGGCGAAGGACTACGGCTTCGTCGACCACGTCGTCCAGCGGGCCCGCCAGGTCCCCAGCGAAGGACCGGTGAGCT
GA

Upstream 100 bases:

>100_bases
GAGCGCGAACATCGAAGGAGAAGCACCGGAACCGGCTCGTGTCACAGATAGTGTCGAGCCGGTCAATCAGACGCCGCCGA
AGGAAGCCGAGGATCCGACC

Downstream 100 bases:

>100_bases
CGCCCGCCGCGGCAGCGAGCCGTCCCGACCCTCGTCACCCGCTCTCCTCGGAGGCAGTCACCATGCACGGACCACAGGGC
TACTACGGAACGCAGAGCCG

Product: endopeptidase Clp

Products: NA

Alternate protein names: Endopeptidase Clp 1 [H]

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MSDIAAPGLAVPGPSLRSPGQNGPGFDEQVFNRLLRERIIFLGSVVEDSIANAICAQLLLLNAEDPERDIFLYINSPGGS
VSAGMAIYDTMQYVENDVATVSLGLAASMGQFLLCAGAPGKRYSLPHARIMMHQPSGGIGGTASDIAIQAEQMLYTKRMM
QERIAFHTGQPVEQIERDSDRDRWFTADEAKDYGFVDHVVQRARQVPSEGPVS

Sequences:

>Translated_213_residues
MSDIAAPGLAVPGPSLRSPGQNGPGFDEQVFNRLLRERIIFLGSVVEDSIANAICAQLLLLNAEDPERDIFLYINSPGGS
VSAGMAIYDTMQYVENDVATVSLGLAASMGQFLLCAGAPGKRYSLPHARIMMHQPSGGIGGTASDIAIQAEQMLYTKRMM
QERIAFHTGQPVEQIERDSDRDRWFTADEAKDYGFVDHVVQRARQVPSEGPVS
>Mature_212_residues
SDIAAPGLAVPGPSLRSPGQNGPGFDEQVFNRLLRERIIFLGSVVEDSIANAICAQLLLLNAEDPERDIFLYINSPGGSV
SAGMAIYDTMQYVENDVATVSLGLAASMGQFLLCAGAPGKRYSLPHARIMMHQPSGGIGGTASDIAIQAEQMLYTKRMMQ
ERIAFHTGQPVEQIERDSDRDRWFTADEAKDYGFVDHVVQRARQVPSEGPVS

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Homo sapiens, GI5174419, Length=171, Percent_Identity=50.2923976608187, Blast_Score=183, Evalue=1e-46,
Organism=Escherichia coli, GI1786641, Length=198, Percent_Identity=53.030303030303, Blast_Score=221, Evalue=4e-59,
Organism=Caenorhabditis elegans, GI17538017, Length=180, Percent_Identity=49.4444444444444, Blast_Score=182, Evalue=8e-47,
Organism=Drosophila melanogaster, GI20129427, Length=185, Percent_Identity=50.2702702702703, Blast_Score=184, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907
- InterPro:   IPR018215 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 23128; Mature: 22997

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS00382 CLP_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDIAAPGLAVPGPSLRSPGQNGPGFDEQVFNRLLRERIIFLGSVVEDSIANAICAQLLL
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNAEDPERDIFLYINSPGGSVSAGMAIYDTMQYVENDVATVSLGLAASMGQFLLCAGAPG
HCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCC
KRYSLPHARIMMHQPSGGIGGTASDIAIQAEQMLYTKRMMQERIAFHTGQPVEQIERDSD
CCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCC
RDRWFTADEAKDYGFVDHVVQRARQVPSEGPVS
CCCEEECCCCCCCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SDIAAPGLAVPGPSLRSPGQNGPGFDEQVFNRLLRERIIFLGSVVEDSIANAICAQLLL
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNAEDPERDIFLYINSPGGSVSAGMAIYDTMQYVENDVATVSLGLAASMGQFLLCAGAPG
HCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCC
KRYSLPHARIMMHQPSGGIGGTASDIAIQAEQMLYTKRMMQERIAFHTGQPVEQIERDSD
CCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCC
RDRWFTADEAKDYGFVDHVVQRARQVPSEGPVS
CCCEEECCCCCCCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA